Topoisomerases Modulate the Timing of Meiotic DNA Breakage and Chromosome Morphogenesis in Saccharomyces cerevisiae

SNP-ChIP: a versatile and tag-free method to quantify changes in protein binding across the genome

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Persistent DNA-break potential near telomeres increases initiation of meiotic recombination on short chromosomes

(2019) Vijayalakshmi V. Subramanian et al.   Nature Communications

The demethylase NMAD-1 regulates DNA replication and repair in the Caenorhabditis elegans germline

(2019) Simon Yuan Wang et al.   PLoS Genetics

A nucleotide resolution map of Top2-linked DNA breaks in the yeast and human genome

(2019) William H. Gittens et al.   Nature Communications

Pervasive, Coordinated Protein-Level Changes Driven by Transcript Isoform Switching during Meiosis

(2018) Ze Cheng et al.   CELL

TOPII and chromosome movement help remove interlocks between entangled chromosomes during meiosis

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Condensin-Dependent Chromatin Compaction Represses Transcription Globally during Quiescence

(2018) Sarah G. Swygert et al.   MOLECULAR CELL

Contrasting evolutionary genome dynamics between domesticated and wild yeasts

(2017) Jia-Xing Yue et al.   NATURE GENETICS

Reduced dosage of the chromosome axis factor Red1 selectively disrupts the meiotic recombination checkpoint in Saccharomyces cerevisiae

(2017) Tovah E. Markowitz et al.   PLoS Genetics

Meiotic recombination modulates the structure and dynamics of the synaptonemal complex during C. elegans meiosis

(2017) Divya Pattabiraman et al.   PLoS Genetics

The Identification of a Novel Mutant Allele of topoisomerase II in Caenorhabditis elegans Reveals a Unique Role in Chromosome Segregation During Spermatogenesis

(2016) Aimee Jaramillo-Lambert et al.   GENETICS

Roles of eukaryotic topoisomerases in transcription, replication and genomic stability

(2016) Yves Pommier et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Chromosome Synapsis Alleviates Mek1-Dependent Suppression of Meiotic DNA Repair

(2016) Vijayalakshmi V. Subramanian et al.   PLOS BIOLOGY

The Identification of a Novel Mutant Allele of topoisomerase II in Caenorhabditis elegans Reveals a Unique Role in Chromosome Segregation During Spermatogenesis

(2016) Aimee Jaramillo-Lambert et al.   GENETICS

High-Resolution Global Analysis of the Influences of Bas1 and Ino4 Transcription Factors on Meiotic DNA Break Distributions inSaccharomyces cerevisiae

(2015) Xuan Zhu et al.   GENETICS

Top3-Rmi1 DNA Single-Strand Decatenase Is Integral to the Formation and Resolution of Meiotic Recombination Intermediates

(2015) Hardeep Kaur et al.   MOLECULAR CELL

Pervasive and Essential Roles of the Top3-Rmi1 Decatenase Orchestrate Recombination and Facilitate Chromosome Segregation in Meiosis

(2015) Shangming Tang et al.   MOLECULAR CELL

The yeast genome undergoes significant topological reorganization in quiescence

(2015) Mark T. Rutledge et al.   NUCLEIC ACIDS RESEARCH

Nonparadoxical evolutionary stability of the recombination initiation landscape in yeast

(2015) I. Lam et al.   SCIENCE

Recombination, Pairing, and Synapsis of Homologs during Meiosis

(2015) Denise Zickler et al.   Cold Spring Harbor Perspectives in Biology

Transcription dynamically patterns the meiotic chromosome-axis interface

(2015) Xiaoji Sun et al.   eLife

High-Resolution Global Analysis of the Influences of Bas1 and Ino4 Transcription Factors on Meiotic DNA Break Distributions inSaccharomyces cerevisiae

(2015) Xuan Zhu et al.   GENETICS

Topoisomerase II mediates meiotic crossover interference

(2014) Liangran Zhang et al.   NATURE

Homologue engagement controls meiotic DNA break number and distribution

(2014) Drew Thacker et al.   NATURE

Mechanism and Regulation of Meiotic Recombination Initiation

(2014) Isabel Lam et al.   Cold Spring Harbor Perspectives in Biology

Topoisomerase II Is Required for the Proper Separation of Heterochromatic Regions during Drosophila melanogaster Female Meiosis

(2014) Stacie E. Hughes et al.   PLoS Genetics

The Analysis of Mutant Alleles of Different Strength Reveals Multiple Functions of Topoisomerase 2 in Regulation of Drosophila Chromosome Structure

(2014) Valentina Mengoli et al.   PLoS Genetics

featureCounts: an efficient general purpose program for assigning sequence reads to genomic features

(2013) Y. Liao et al.   BIOINFORMATICS

Cohesin removal precedes topoisomerase IIα-dependent decatenation at centromeres in male mammalian meiosis II

(2013) Rocío Gómez et al.   CHROMOSOMA

Programmed induction of DNA double strand breaks during meiosis: setting up communication between DNA and the chromosome structure

(2013) Valérie Borde et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

A novel chromatin tether domain controls topoisomerase IIα dynamics and mitotic chromosome formation

(2013) Andrew B. Lane et al.   JOURNAL OF CELL BIOLOGY

Meiotic chromosome structures constrain and respond to designation of crossover sites

(2013) Diana E. Libuda et al.   NATURE

Count-based differential expression analysis of RNA sequencing data using R and Bioconductor

(2013) Simon Anders et al.   Nature Protocols

Transcription-generated torsional stress destabilizes nucleosomes

(2013) Sheila S Teves et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Pch2 is a hexameric ring ATPase that remodels the chromosome axis protein Hop1

(2013) C. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ATR/Mec1 prevents lethal meiotic recombination initiation on partially replicated chromosomes in budding yeast

(2013) Hannah G Blitzblau et al.   eLife

TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions

(2013) Daehwan Kim et al.   GENOME BIOLOGY

BLM Helicase Ortholog Sgs1 Is a Central Regulator of Meiotic Recombination Intermediate Metabolism

(2012) Arnaud De Muyt et al.   MOLECULAR CELL

Measurement of mRNA abundance using RNA-seq data: RPKM measure is inconsistent among samples

(2012) Günter P. Wagner et al.   THEORY IN BIOSCIENCES

A Hierarchical Combination of Factors Shapes the Genome-wide Topography of Yeast Meiotic Recombination Initiation

(2011) Jing Pan et al.   CELL

All tangled up: how cells direct, manage and exploit topoisomerase function

(2011) Seychelle M. Vos et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Topoisomerase II binds nucleosome-free DNA and acts redundantly with topoisomerase I to enhance recruitment of RNA Pol II in budding yeast

(2011) A. S. Sperling et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Mec1- and PP4-Dependent Checkpoint Couples Centromere Pairing to Meiotic Recombination

(2010) Jill E. Falk et al.   DEVELOPMENTAL CELL

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

Yeast Pch2 promotes domainal axis organization, timely recombination progression, and arrest of defective recombinosomes during meiosis

(2008) G. V. Borner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Model-based Analysis of ChIP-Seq (MACS)

(2008) Yong Zhang et al.   GENOME BIOLOGY