标题
Autophagy promotes mammalian survival by suppressing oxidative stress and p53
作者
关键词
-
出版物
GENES & DEVELOPMENT
Volume 34, Issue 9-10, Pages 688-700
出版商
Cold Spring Harbor Laboratory
发表日期
2020-03-20
DOI
10.1101/gad.335570.119
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Targeted therapy based on p53 reactivation reduces both glioblastoma cell growth and resistance to temozolomide
- (2019) Iris Forte et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- LC3-Associated Endocytosis Facilitates β-Amyloid Clearance and Mitigates Neurodegeneration in Murine Alzheimer’s Disease
- (2019) Bradlee L. Heckmann et al. CELL
- Role of tumor and host autophagy in cancer metabolism
- (2019) Laura Poillet-Perez et al. GENES & DEVELOPMENT
- Cancer Cells Upregulate NRF2 Signaling to Adapt to Autophagy Inhibition
- (2019) Christina G. Towers et al. DEVELOPMENTAL CELL
- Cellular quality control by the ubiquitin-proteasome system and autophagy
- (2019) Christian Pohl et al. SCIENCE
- Nutlin-3, A p53-Mdm2 Antagonist for Nasopharyngeal Carcinoma Treatment
- (2018) Voon Yee-Lin et al. MINI-REVIEWS IN MEDICINAL CHEMISTRY
- Autophagy protein ATG16L1 prevents necroptosis in the intestinal epithelium
- (2017) Yu Matsuzawa-Ishimoto et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Census and evaluation of p53 target genes
- (2017) M Fischer ONCOGENE
- Intrinsic Autophagy Is Required for the Maintenance of Intestinal Stem Cells and for Irradiation-Induced Intestinal Regeneration
- (2017) Jumpei Asano et al. Cell Reports
- Autophagy provides metabolic substrates to maintain energy charge and nucleotide pools in Ras-driven lung cancer cells
- (2016) Jessie Yanxiang Guo et al. GENES & DEVELOPMENT
- p62/Sqstm1 promotes malignancy of HCV-positive hepatocellular carcinoma through Nrf2-dependent metabolic reprogramming
- (2016) Tetsuya Saito et al. Nature Communications
- Sequential cancer mutations in cultured human intestinal stem cells
- (2015) Jarno Drost et al. NATURE
- Molecular characterization of LC3-associated phagocytosis reveals distinct roles for Rubicon, NOX2 and autophagy proteins
- (2015) Jennifer Martinez et al. NATURE CELL BIOLOGY
- p53 in survival, death and metabolic health: a lifeguard with a licence to kill
- (2015) Flore Kruiswijk et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Autophagy at the crossroads of catabolism and anabolism
- (2015) Jasvinder Kaur et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Inhibition of autophagy attenuates pancreatic cancer growth independent ofTP53/TRP53status
- (2014) Annan Yang et al. Autophagy
- Redox regulation of antioxidants, autophagy, and the response to stress: Implications for electrophile therapeutics
- (2014) Anna-Liisa Levonen et al. FREE RADICAL BIOLOGY AND MEDICINE
- Functional Role of Autophagy-Mediated Proteome Remodeling in Cell Survival Signaling and Innate Immunity
- (2014) Robin Mathew et al. MOLECULAR CELL
- Quantitative proteomics identifies NCOA4 as the cargo receptor mediating ferritinophagy
- (2014) Joseph D. Mancias et al. NATURE
- Autophagy Is Critical for Pancreatic Tumor Growth and Progression in Tumors with p53 Alterations
- (2014) A. Yang et al. Cancer Discovery
- Autophagy Is Required for Glucose Homeostasis and Lung Tumor Maintenance
- (2014) G. Karsli-Uzunbas et al. Cancer Discovery
- Noncanonical Autophagy Promotes the Visual Cycle
- (2013) Ji-Young Kim et al. CELL
- Global genomic profiling reveals an extensive p53-regulated autophagy program contributing to key p53 responses
- (2013) D. Kenzelmann Broz et al. GENES & DEVELOPMENT
- Autophagy suppresses progression of K-ras-induced lung tumors to oncocytomas and maintains lipid homeostasis
- (2013) J. Y. Guo et al. GENES & DEVELOPMENT
- Phosphorylation of p62 Activates the Keap1-Nrf2 Pathway during Selective Autophagy
- (2013) Yoshinobu Ichimura et al. MOLECULAR CELL
- p53 status determines the role of autophagy in pancreatic tumour development
- (2013) Mathias T. Rosenfeldt et al. NATURE
- Autophagy Opposes p53-Mediated Tumor Barrier to Facilitate Tumorigenesis in a Model of PALB2-Associated Hereditary Breast Cancer
- (2013) Y. Huo et al. Cancer Discovery
- Autophagy Sustains Mitochondrial Glutamine Metabolism and Growth of BrafV600E-Driven Lung Tumors
- (2013) A. M. Strohecker et al. Cancer Discovery
- DRAM-1 encodes multiple isoforms that regulate autophagy
- (2012) Li Yen Mah et al. Autophagy
- P53 Mdm2 Inhibitors
- (2012) Kareem Khoury et al. CURRENT PHARMACEUTICAL DESIGN
- Autophagy: Renovation of Cells and Tissues
- (2011) Noboru Mizushima et al. CELL
- Pancreatic cancers require autophagy for tumor growth
- (2011) S. Yang et al. GENES & DEVELOPMENT
- Autophagy machinery mediates macroendocytic processing and entotic cell death by targeting single membranes
- (2011) Oliver Florey et al. NATURE CELL BIOLOGY
- Microtubule-associated protein 1 light chain 3 alpha (LC3)-associated phagocytosis is required for the efficient clearance of dead cells
- (2011) J. Martinez et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The role of the Atg1/ULK1 complex in autophagy regulation
- (2010) Noboru Mizushima CURRENT OPINION IN CELL BIOLOGY
- Molecular mechanism and physiological role of pexophagy
- (2010) Ravi Manjithaya et al. FEBS LETTERS
- A Noncanonical Mechanism of Nrf2 Activation by Autophagy Deficiency: Direct Interaction between Keap1 and p62
- (2010) A. Lau et al. MOLECULAR AND CELLULAR BIOLOGY
- The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1
- (2010) Masaaki Komatsu et al. NATURE CELL BIOLOGY
- Autophagy and Metabolism
- (2010) J. D. Rabinowitz et al. SCIENCE
- p53 mediates mitochondria dysfunction-triggered autophagy activation and cell death in rat striatum
- (2009) Xing-Ding Zhang et al. Autophagy
- Autophagy Suppresses Tumorigenesis through Elimination of p62
- (2009) Robin Mathew et al. CELL
- Mdm2-mediated ubiquitylation: p53 and beyond
- (2009) J-C Marine et al. CELL DEATH AND DIFFERENTIATION
- PUMA- and Bax-induced autophagy contributes to apoptosis
- (2009) K S Yee et al. CELL DEATH AND DIFFERENTIATION
- A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells
- (2008) Ken Cadwell et al. NATURE
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationPublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More