A hypothesis for pathobiology and treatment of COVID‐19 : The centrality of ACE1 / ACE2 imbalance
出版年份 2020 全文链接
标题
A hypothesis for pathobiology and treatment of
COVID‐19
: The centrality of
ACE1
/
ACE2
imbalance
作者
关键词
-
出版物
BRITISH JOURNAL OF PHARMACOLOGY
Volume -, Issue -, Pages -
出版商
Wiley
发表日期
2020-04-25
DOI
10.1111/bph.15082
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- COVID-19: Gastrointestinal manifestations and potential fecal-oral transmission
- (2020) Jinyang Gu et al. GASTROENTEROLOGY
- SARS-CoV-2: a potential novel etiology of fulminant myocarditis
- (2020) Chen Chen et al. HERZ
- Angiotensin-converting enzyme 2 (ACE2) as a SARS-CoV-2 receptor: molecular mechanisms and potential therapeutic target
- (2020) Haibo Zhang et al. INTENSIVE CARE MEDICINE
- Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China
- (2020) Zunyou Wu et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- The epidemiology and pathogenesis of coronavirus disease (COVID-19) outbreak
- (2020) Hussin A. Rothan et al. JOURNAL OF AUTOIMMUNITY
- Coronavirus infections and immune responses
- (2020) Geng Li et al. JOURNAL OF MEDICAL VIROLOGY
- Understanding of COVID‐19 based on current evidence
- (2020) Pengfei Sun et al. JOURNAL OF MEDICAL VIROLOGY
- Pulmonary pathology of early phase 2019 novel coronavirus (COVID-19) pneumonia in two patients with lung cancer
- (2020) Sufang Tian et al. Journal of Thoracic Oncology
- Receptor recognition by novel coronavirus from Wuhan: An analysis based on decade-long structural studies of SARS
- (2020) Yushun Wan et al. JOURNAL OF VIROLOGY
- Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China
- (2020) Chaolin Huang et al. LANCET
- COVID-19: combining antiviral and anti-inflammatory treatments
- (2020) Justin Stebbing et al. LANCET INFECTIOUS DISEASES
- A pneumonia outbreak associated with a new coronavirus of probable bat origin
- (2020) Peng Zhou et al. NATURE
- Time Course of Lung Changes On Chest CT During Recovery From 2019 Novel Coronavirus (COVID-19) Pneumonia
- (2020) Feng Pan et al. RADIOLOGY
- Clinical and biochemical indexes from 2019-nCoV infected patients linked to viral loads and lung injury
- (2020) Yingxia Liu et al. Science China-Life Sciences
- High expression of ACE2 receptor of 2019-nCoV on the epithelial cells of oral mucosa
- (2020) Hao Xu et al. International Journal of Oral Science
- Pathological findings of COVID-19 associated with acute respiratory distress syndrome
- (2020) Zhe Xu et al. Lancet Respiratory Medicine
- The Vasoactive Mas Receptor in Essential Hypertension
- (2020) Amalie L. Povlsen et al. Journal of Clinical Medicine
- Clinical Features of 85 Fatal Cases of COVID-19 from Wuhan. A Retrospective Observational Study
- (2020) Yingzhen Du et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Inhibition of SARS-CoV-2 Infections in Engineered Human Tissues Using Clinical-Grade Soluble Human ACE2
- (2020) Vanessa Monteil et al. CELL
- Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein
- (2020) Alexandra C. Walls et al. CELL
- Risks of ACE Inhibitor and ARB Usage in COVID‐19: Evaluating the Evidence
- (2020) Krishna Sriram et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- SARS-CoV-2: a storm is raging
- (2020) Savannah F. Pedersen et al. JOURNAL OF CLINICAL INVESTIGATION
- Coronavirus Disease 2019 (COVID‐19): What we know?
- (2020) Feng He et al. JOURNAL OF MEDICAL VIROLOGY
- The Novel Coronavirus 2019 epidemic and kidneys
- (2020) Saraladevi Naicker et al. KIDNEY INTERNATIONAL
- Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study
- (2020) Fei Zhou et al. LANCET
- Temporal profiles of viral load in posterior oropharyngeal saliva samples and serum antibody responses during infection by SARS-CoV-2: an observational cohort study
- (2020) Kelvin Kai-Wang To et al. LANCET INFECTIOUS DISEASES
- Breadth of concomitant immune responses prior to patient recovery: a case report of non-severe COVID-19
- (2020) Irani Thevarajan et al. NATURE MEDICINE
- Renin–Angiotensin–Aldosterone System Inhibitors in Patients with Covid-19
- (2020) Muthiah Vaduganathan et al. NEW ENGLAND JOURNAL OF MEDICINE
- Susceptibility of ferrets, cats, dogs, and other domesticated animals to SARS–coronavirus 2
- (2020) Jianzhong Shi et al. SCIENCE
- SARS-CoV-2 (COVID-19) by the numbers
- (2020) Yinon M Bar-On et al. eLife
- Single-cell RNA-seq data analysis on the receptor ACE2 expression reveals the potential risk of different human organs vulnerable to 2019-nCoV infection
- (2020) Xin Zou et al. Frontiers of Medicine
- The Renin-Angiotensin System: Going Beyond the Classical Paradigms
- (2019) Robson A. Souza Santos et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Exogenous angiotensin (1-7) directly inhibits epithelial-mesenchymal transformation induced by transforming growth factor-β1 in alveolar epithelial cells
- (2019) Min Shao et al. BIOMEDICINE & PHARMACOTHERAPY
- THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Ion channels
- (2019) Stephen P H Alexander et al. BRITISH JOURNAL OF PHARMACOLOGY
- THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: G protein‐coupled receptors
- (2019) Stephen P H Alexander et al. BRITISH JOURNAL OF PHARMACOLOGY
- THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Enzymes
- (2019) Stephen P H Alexander et al. BRITISH JOURNAL OF PHARMACOLOGY
- A Dynamic Variation of Pulmonary ACE2 Is Required to Modulate Neutrophilic Inflammation in Response to Pseudomonas aeruginosa Lung Infection in Mice
- (2019) Chhinder P. Sodhi et al. JOURNAL OF IMMUNOLOGY
- Renin-angiotensin-system, a potential pharmacological candidate, in acute respiratory distress syndrome during mechanical ventilation
- (2019) Di Wang et al. PULMONARY PHARMACOLOGY & THERAPEUTICS
- Targeting the renin–angiotensin system as novel therapeutic strategy for pulmonary diseases
- (2018) Wan Shun Daniel Tan et al. CURRENT OPINION IN PHARMACOLOGY
- Eccentric Overload Muscle Damage is Attenuated By a Novel Angiotensin- (1-7) Treatment
- (2018) Lenice Becker et al. INTERNATIONAL JOURNAL OF SPORTS MEDICINE
- Novel ACE2-Fc chimeric fusion provides long-lasting hypertension control and organ protection in mouse models of systemic renin angiotensin system activation
- (2018) Pan Liu et al. KIDNEY INTERNATIONAL
- Angiotensin II Signal Transduction: An Update on Mechanisms of Physiology and Pathophysiology
- (2018) Steven J. Forrester et al. PHYSIOLOGICAL REVIEWS
- The ACE2/Angiotensin-(1–7)/MAS Axis of the Renin-Angiotensin System: Focus on Angiotensin-(1–7)
- (2018) Robson Augusto Souza Santos et al. PHYSIOLOGICAL REVIEWS
- Immunosenescence and Inflamm-Aging As Two Sides of the Same Coin: Friends or Foes?
- (2018) Tamas Fulop et al. Frontiers in Immunology
- Inflammageing: chronic inflammation in ageing, cardiovascular disease, and frailty
- (2018) Luigi Ferrucci et al. Nature Reviews Cardiology
- Immunomodulatory properties of captopril, an ACE inhibitor, on LPS-induced lung inflammation and fibrosis as well as oxidative stress
- (2018) Javad Boskabadi et al. INFLAMMOPHARMACOLOGY
- Angiotensin-(1-7)-mediated Mas1 receptor/NF-κB-p65 signaling is involved in a cigarette smoke-induced chronic obstructive pulmonary disease mouse model
- (2017) Yong Zhang et al. ENVIRONMENTAL TOXICOLOGY
- The IUPHAR/BPS Guide to PHARMACOLOGY in 2018: updates and expansion to encompass the new guide to IMMUNOPHARMACOLOGY
- (2017) Simon D Harding et al. NUCLEIC ACIDS RESEARCH
- Pathogenic human coronavirus infections: causes and consequences of cytokine storm and immunopathology
- (2017) Rudragouda Channappanavar et al. Seminars in Immunopathology
- Angiotensin-(1-7) Promotes Resolution of Neutrophilic Inflammation in a Model of Antigen-Induced Arthritis in Mice
- (2017) Lívia C. Barroso et al. Frontiers in Immunology
- Chronic allergic pulmonary inflammation is aggravated in angiotensin-(1–7) Mas receptor knockout mice
- (2016) Giselle S. Magalhães et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Role of the ACE2/Angiotensin 1–7 Axis of the Renin–Angiotensin System in Heart Failure
- (2016) Vaibhav B. Patel et al. CIRCULATION RESEARCH
- Role of the receptor Mas in macrophage-mediated inflammation in vivo
- (2016) Anna Hammer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Angiotensin receptor blockers: Focus on cardiac and renal injury
- (2016) Somasundaram Arumugam et al. TRENDS IN CARDIOVASCULAR MEDICINE
- The Effect of Endogenous Angiotensin II on Alveolar Fluid Clearance in Rats with Acute Lung Injury
- (2016) Jia Deng et al. Canadian Respiratory Journal
- The Angiotensin-Converting Enzyme 2/Angiotensin (1–7)/Mas Axis Protects Against Lung Fibroblast Migration and Lung Fibrosis by Inhibiting the NOX4-Derived ROS-Mediated RhoA/Rho Kinase Pathway
- (2015) Ying Meng et al. ANTIOXIDANTS & REDOX SIGNALING
- Mesenchymal Stem Cells Overexpressing Angiotensin-Converting Enzyme 2 Rescue Lipopolysaccharide-Induced Lung Injury
- (2015) Hongli He et al. CELL TRANSPLANTATION
- Angiotensin-Converting Enzyme 2 Attenuates Bleomycin-Induced Lung Fibrosis in Mice
- (2015) Lifang Wang et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Immune Cell and Other Noncardiomyocyte Regulation of Cardiac Hypertrophy and Remodeling
- (2015) R. A. Frieler et al. CIRCULATION
- Correction: The Role of Angiotensin II and Cyclic AMP in Alveolar Active Sodium Transport
- (2015) Reem Ismael-Badarneh et al. PLoS One
- Angiotensin II receptor blocker as a novel therapy in acute lung injury induced by avian influenza A H5N1 virus infection in mouse
- (2015) YiWu Yan et al. Science China-Life Sciences
- Angiotensin-Converting Enzyme Inhibition Attenuates Lipopolysaccharide-Induced Lung Injury by Regulating the Balance Between Angiotensin-Converting Enzyme and Angiotensin-Converting Enzyme 2 and Inhibiting Mitogen-Activated Protein Kinase Activation
- (2015) Yingchuan Li et al. SHOCK
- Development of animal models against emerging coronaviruses: From SARS to MERS coronavirus
- (2015) Troy C. Sutton et al. VIROLOGY
- T cell-mediated immune response to respiratory coronaviruses
- (2014) Rudragouda Channappanavar et al. IMMUNOLOGIC RESEARCH
- Tanshinone IIA Attenuates Bleomycin-Induced Pulmonary Fibrosis via Modulating Angiotensin-Converting Enzyme 2/ Angiotensin-(1-7) Axis in Rats
- (2014) Huajie Wu et al. International Journal of Medical Sciences
- T Cell Responses to Whole SARS Coronavirus in Humans
- (2014) C. K.-f. Li et al. JOURNAL OF IMMUNOLOGY
- Molecular pathology of emerging coronavirus infections
- (2014) Lisa E Gralinski et al. JOURNAL OF PATHOLOGY
- Losartan attenuates microvascular permeability in mechanical ventilator-induced lung injury in diabetic mice
- (2014) Chang Chen et al. MOLECULAR BIOLOGY REPORTS
- Phagocytic cells contribute to the antibody-mediated elimination of pulmonary-infected SARS coronavirus
- (2014) Fumihiko Yasui et al. VIROLOGY
- Tissue Renin–Angiotensin Systems: A Unifying Hypothesis of Metabolic Disease
- (2014) Jeppe Skov et al. Frontiers in Endocrinology
- Abrogation of ER stress-induced apoptosis of alveolar epithelial cells by angiotensin 1–7
- (2013) Bruce D. Uhal et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- WNT/β-Catenin Signaling Induces IL-1β Expression by Alveolar Epithelial Cells in Pulmonary Fibrosis
- (2013) Verena Aumiller et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Angiotensin-Converting Enzyme 2/Angiotensin-(1-7)/Mas Axis Protects against Lung Fibrosis by Inhibiting the MAPK/NF-κB Pathway
- (2013) Ying Meng et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Fibrosis of two: Epithelial cell-fibroblast interactions in pulmonary fibrosis
- (2013) Norihiko Sakai et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Angiotensin II type 1 and 2 receptors and lymphatic vessels modulate lung remodeling and fibrosis in systemic sclerosis and idiopathic pulmonary fibrosis
- (2013) ER Parra et al. Clinics
- Inhalation delivery of Telmisartan enhances intratumoral distribution of nanoparticles in lung cancer models
- (2013) Chandraiah Godugu et al. JOURNAL OF CONTROLLED RELEASE
- Novel Inhibitors of Severe Acute Respiratory Syndrome Coronavirus Entry That Act by Three Distinct Mechanisms
- (2013) A. O. Adedeji et al. JOURNAL OF VIROLOGY
- Population-Based Study of Statins, Angiotensin II Receptor Blockers, and Angiotensin-Converting Enzyme Inhibitors on Pneumonia-Related Outcomes
- (2012) E. M. Mortensen et al. CLINICAL INFECTIOUS DISEASES
- Renin–angiotensin system blockade: a novel therapeutic approach in chronic obstructive pulmonary disease
- (2012) Dinesh Shrikrishna et al. CLINICAL SCIENCE
- Decreased Risk of Radiation Pneumonitis With Incidental Concurrent Use of Angiotensin-Converting Enzyme Inhibitors and Thoracic Radiation Therapy
- (2012) Jordan Kharofa et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- Apoptosis signaling in influenza virus propagation, innate host defense, and lung injury
- (2012) Susanne Herold et al. JOURNAL OF LEUKOCYTE BIOLOGY
- The Role of Alveolar Epithelial Cells in Initiating and Shaping Pulmonary Immune Responses: Communication between Innate and Adaptive Immune Systems
- (2012) Olga D. Chuquimia et al. PLoS One
- Risk of pneumonia associated with use of angiotensin converting enzyme inhibitors and angiotensin receptor blockers: systematic review and meta-analysis
- (2012) D. Caldeira et al. BMJ-British Medical Journal
- Angiotensin II increases the permeability and PV-1 expression of endothelial cells
- (2011) Csaba Bodor et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Regulation of alveolar epithelial cell survival by the ACE-2/angiotensin 1–7/Mas axis
- (2011) Bruce D. Uhal et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Angiotensin signalling in pulmonary fibrosis
- (2011) Bruce D. Uhal et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Mitigation of Late Renal and Pulmonary Injury After Hematopoietic Stem Cell Transplantation
- (2011) Eric P. Cohen et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- Acute respiratory distress syndrome leads to reduced ratio of ACE/ACE2 activities and is prevented by angiotensin-(1-7) or an angiotensin II receptor antagonist
- (2011) Roelie M Wösten-van Asperen et al. JOURNAL OF PATHOLOGY
- Unknown
- (2011) Jochen Grommes et al. MOLECULAR MEDICINE
- Radiation damage to the lung: Mitigation by angiotensin-converting enzyme (ACE) inhibitors
- (2011) MEETHA MEDHORA et al. RESPIROLOGY
- Over-expression of angiotensin II type 2 receptor gene induces cell death in lung adenocarcinoma cells
- (2010) Lara Pickel et al. CANCER BIOLOGY & THERAPY
- Differential susceptibility to epithelial-mesenchymal transition (EMT) of alveolar, bronchial and intestinal epithelial cells in vitro and the effect of angiotensin II receptor inhibition
- (2010) Stephen T. Buckley et al. CELL AND TISSUE RESEARCH
- Angiotensin-II-induced apoptosis requires regulation of nucleolin and Bcl-xL by SHP-2 in primary lung endothelial cells
- (2010) Y. H. Lee et al. JOURNAL OF CELL SCIENCE
- Anti-Inflammatory Effects of the Activation of the Angiotensin-(1-7) Receptor, Mas, in Experimental Models of Arthritis
- (2010) K. D. da Silveira et al. JOURNAL OF IMMUNOLOGY
- Angiotensin1-9 antagonises pro-hypertrophic signalling in cardiomyocytes via the angiotensin type 2 receptor
- (2010) M. Flores-Muñoz et al. JOURNAL OF PHYSIOLOGY-LONDON
- Chronic Inflammation in Obesity and the Metabolic Syndrome
- (2010) Rosário Monteiro et al. MEDIATORS OF INFLAMMATION
- Losartan attenuates chronic cigarette smoke exposure-induced pulmonary arterial hypertension in rats: Possible involvement of angiotensin-converting enzyme-2
- (2010) Su-Xia Han et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- SARS-coronavirus modulation of myocardial ACE2 expression and inflammation in patients with SARS
- (2009) G. Y. Oudit et al. EUROPEAN JOURNAL OF CLINICAL INVESTIGATION
- The angiotensin II type 2 receptor in cardiovascular disease
- (2009) Catherine A Lemarié et al. JOURNAL OF THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM
- Differential Downregulation of ACE2 by the Spike Proteins of Severe Acute Respiratory Syndrome Coronavirus and Human Coronavirus NL63
- (2009) I. Glowacka et al. JOURNAL OF VIROLOGY
- Fas inhibition attenuates lipopolysaccharide-induced apoptosis and cytokine release of rat type II alveolar epithelial cells
- (2009) Xinhua Ma et al. MOLECULAR BIOLOGY REPORTS
- LOSARTAN PREVENTS SEPSIS-INDUCED ACUTE LUNG INJURY AND DECREASES ACTIVATION OF NUCLEAR FACTORκB AND MITOGEN-ACTIVATED PROTEIN KINASES
- (2009) Lihan Shen et al. SHOCK
- Evasion by Stealth: Inefficient Immune Activation Underlies Poor T Cell Response and Severe Disease in SARS-CoV-Infected Mice
- (2009) Jincun Zhao et al. PLoS Pathogens
- Angiotensin converting enzyme-2 is protective but downregulated in human and experimental lung fibrosis
- (2008) Xiaopeng Li et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- AT2 receptors: Functional relevance in cardiovascular disease
- (2008) Emma S. Jones et al. PHARMACOLOGY & THERAPEUTICS
- Modulation of TNF- -converting enzyme by the spike protein of SARS-CoV and ACE2 induces TNF- production and facilitates viral entry
- (2008) S. Haga et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- ACE mediates ventilator-induced lung injury in rats via angiotensin II but not bradykinin
- (2007) R. M. Wosten-van Asperen et al. EUROPEAN RESPIRATORY JOURNAL
- SARS-CoV replicates in primary human alveolar type II cell cultures but not in type I-like cells
- (2007) Eric C. Mossel et al. VIROLOGY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search