Targeted Inhibition of Gut Microbial Trimethylamine N-Oxide Production Reduces Renal Tubulointerstitial Fibrosis and Functional Impairment in a Murine Model of Chronic Kidney Disease
出版年份 2020 全文链接
标题
Targeted Inhibition of Gut Microbial Trimethylamine N-Oxide Production Reduces Renal Tubulointerstitial Fibrosis and Functional Impairment in a Murine Model of Chronic Kidney Disease
作者
关键词
-
出版物
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
Volume 40, Issue 5, Pages 1239-1255
出版商
Ovid Technologies (Wolters Kluwer Health)
发表日期
2020-03-26
DOI
10.1161/atvbaha.120.314139
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Trimethylamine N-Oxide and Cardiovascular Outcomes in Patients with End-stage Kidney Disease Receiving Maintenance Hemodialysis
- (2019) Jason R. Stubbs et al. Clinical Journal of the American Society of Nephrology
- Widespread Translational Control of Fibrosis in the Human Heart by RNA-Binding Proteins
- (2019) Sonia Chothani et al. CIRCULATION
- Trimethylamine N-Oxide Binds and Activates PERK to Promote Metabolic Dysfunction
- (2019) Sifan Chen et al. Cell Metabolism
- Isoproterenol Disrupts Intestinal Barriers Activating Gut-Liver-Axis: Effects on Intestinal Mucus and Vascular Barrier as Entry Sites
- (2019) Marcel Sorribas et al. DIGESTION
- Protein Intake at Twice the RDA in Older Men Increases Circulatory Concentrations of the Microbiome Metabolite Trimethylamine-N-Oxide (TMAO)
- (2019) Mitchell et al. Nutrients
- Mechanisms of Renal Fibrosis
- (2018) Benjamin D. Humphreys Annual Review of Physiology
- Extended Duration Nocturnal Hemodialysis and Changes in Plasma Metabolite Profiles
- (2018) Sahir Kalim et al. Clinical Journal of the American Society of Nephrology
- Development of a gut microbe–targeted nonlethal therapeutic to inhibit thrombosis potential
- (2018) Adam B. Roberts et al. NATURE MEDICINE
- Impact of chronic dietary red meat, white meat, or non-meat protein on trimethylamine N-oxide metabolism and renal excretion in healthy men and women
- (2018) Zeneng Wang et al. EUROPEAN HEART JOURNAL
- Gut microbe-generated metabolite trimethylamine-N-oxide as cardiovascular risk biomarker: a systematic review and dose-response meta-analysis
- (2017) Gabriele Giacomo Schiattarella et al. EUROPEAN HEART JOURNAL
- Circulating trimethylamine N-oxide and the risk of cardiovascular diseases: a systematic review and meta-analysis of 11 prospective cohort studies
- (2017) Jiaqian Qi et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- The Role of β-Adrenergic Overstimulation in the Early Stages of Renal Injury
- (2017) Mariana Charleaux de Ponte et al. KIDNEY & BLOOD PRESSURE RESEARCH
- Evaluation of the impact of gut microbiota on uremic solute accumulation by a CE-TOFMS–based metabolomics approach
- (2017) Eikan Mishima et al. KIDNEY INTERNATIONAL
- Gut Microbiota Metabolites and Risk of Major Adverse Cardiovascular Disease Events and Death: A Systematic Review and Meta‐Analysis of Prospective Studies
- (2017) Yoriko Heianza et al. Journal of the American Heart Association
- TMAO is Associated with Mortality: Impact of Modestly Impaired Renal Function
- (2017) Eke G. Gruppen et al. Scientific Reports
- Modulation of a Circulating Uremic Solute via Rational Genetic Manipulation of the Gut Microbiota
- (2016) A. Sloan Devlin et al. Cell Host & Microbe
- TrimethylamineN-Oxide and Cardiovascular Events in Hemodialysis Patients
- (2016) Tariq Shafi et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Advanced chronic kidney disease populations have elevated trimethylamine N-oxide levels associated with increased cardiovascular events
- (2016) Richard B. Kim et al. KIDNEY INTERNATIONAL
- DADA2: High-resolution sample inference from Illumina amplicon data
- (2016) Benjamin J Callahan et al. NATURE METHODS
- Trimethylamine N‐Oxide Promotes Vascular Inflammation Through Signaling of Mitogen‐Activated Protein Kinase and Nuclear Factor‐κB
- (2016) Marcus M. Seldin et al. Journal of the American Heart Association
- Serum Trimethylamine-N-Oxide Is Strongly Related to Renal Function and Predicts Outcome in Chronic Kidney Disease
- (2016) Catharina Missailidis et al. PLoS One
- Association of FMO3 Variants and Trimethylamine N-Oxide Concentration, Disease Progression, and Mortality in CKD Patients
- (2016) Cassianne Robinson-Cohen et al. PLoS One
- Non-lethal Inhibition of Gut Microbial Trimethylamine Production for the Treatment of Atherosclerosis
- (2015) Zeneng Wang et al. CELL
- Effect of a Symbiotic Gel (Lactobacillus acidophilus + Bifidobacterium lactis + Inulin) on Presence and Severity of Gastrointestinal Symptoms in Hemodialysis Patients
- (2015) Daniela Viramontes-Hörner et al. JOURNAL OF RENAL NUTRITION
- Associations of Trimethylamine N-Oxide With Nutritional and Inflammatory Biomarkers and Cardiovascular Outcomes in Patients New to Dialysis
- (2015) George A. Kaysen et al. JOURNAL OF RENAL NUTRITION
- Serum Trimethylamine-N-Oxide is Elevated in CKD and Correlates with Coronary Atherosclerosis Burden
- (2015) J. R. Stubbs et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Patiromer in Patients with Kidney Disease and Hyperkalemia Receiving RAAS Inhibitors
- (2015) Matthew R. Weir et al. NEW ENGLAND JOURNAL OF MEDICINE
- Renal Denervation Findings on Cardiac and Renal Fibrosis in Rats with Isoproterenol Induced Cardiomyopathy
- (2015) Qian Liu et al. Scientific Reports
- The effect of probiotics on serum levels of cytokine and endotoxin in peritoneal dialysis patients: a randomised, double-blind, placebo-controlled trial
- (2015) I.-K. Wang et al. Beneficial Microbes
- Gut-Microbiota-Metabolite Axis in Early Renal Function Decline
- (2015) Clara Barrios et al. PLoS One
- Mechanism of Prominent Trimethylamine Oxide (TMAO) Accumulation in Hemodialysis Patients
- (2015) Xin Hai et al. PLoS One
- Expansion of Urease- and Uricase-Containing, Indole- and p-Cresol-Forming and Contraction of Short-Chain Fatty Acid-Producing Intestinal Microbiota in ESRD
- (2014) Jakk Wong et al. AMERICAN JOURNAL OF NEPHROLOGY
- Measurement of trimethylamine-N-oxide by stable isotope dilution liquid chromatography tandem mass spectrometry
- (2014) Zeneng Wang et al. ANALYTICAL BIOCHEMISTRY
- Waste Not, Want Not: Why Rarefying Microbiome Data Is Inadmissible
- (2014) Paul J. McMurdie et al. PLoS Computational Biology
- A Combined Epidemiologic and Metabolomic Approach Improves CKD Prediction
- (2013) E. P. Rhee et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- p -Cresyl sulfate causes renal tubular cell damage by inducing oxidative stress by activation of NADPH oxidase
- (2013) Hiroshi Watanabe et al. KIDNEY INTERNATIONAL
- Albuminuria is associated with too few glomeruli and too much testosterone
- (2013) David A. Long et al. KIDNEY INTERNATIONAL
- phyloseq: An R Package for Reproducible Interactive Analysis and Graphics of Microbiome Census Data
- (2013) Paul J. McMurdie et al. PLoS One
- KDOQI Clinical Practice Guideline for Diabetes and CKD: 2012 Update
- (2012) AMERICAN JOURNAL OF KIDNEY DISEASES
- Suppression of Klotho expression by protein-bound uremic toxins is associated with increased DNA methyltransferase expression and DNA hypermethylation
- (2012) Chiao-Yin Sun et al. KIDNEY INTERNATIONAL
- Chronic kidney disease alters intestinal microbial flora
- (2012) Nosratola D. Vaziri et al. KIDNEY INTERNATIONAL
- Uremic Toxins Induce Kidney Fibrosis by Activating Intrarenal Renin–Angiotensin–Aldosterone System Associated Epithelial-to-Mesenchymal Transition
- (2012) Chiao-Yin Sun et al. PLoS One
- Microbial conversion of choline to trimethylamine requires a glycyl radical enzyme
- (2012) S. Craciun et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Early Sympathetic Activation in the Initial Clinical Stages of Chronic Renal Failure
- (2011) Guido Grassi et al. HYPERTENSION
- Transcutaneous assessment of renal function in conscious rats with a device for measuring FITC-sinistrin disappearance curves
- (2011) Daniel Schock-Kusch et al. KIDNEY INTERNATIONAL
- Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease
- (2011) Zeneng Wang et al. NATURE
- p-Cresol and Cardiovascular Risk in Mild-to-Moderate Kidney Disease
- (2010) B. K. I. Meijers et al. Clinical Journal of the American Society of Nephrology
- Discovering the false discovery rate
- (2010) Yoav Benjamini JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES B-STATISTICAL METHODOLOGY
- QIIME allows analysis of high-throughput community sequencing data
- (2010) J Gregory Caporaso et al. NATURE METHODS
- Removal of uraemic retention solutes in standard bicarbonate haemodialysis and long-hour slow-flow bicarbonate haemodialysis
- (2010) C. Basile et al. NEPHROLOGY DIALYSIS TRANSPLANTATION
- Operons
- (2009) Anne E. Osbourn et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Structural Analysis of Sensor Domains from the TMAO-Responsive Histidine Kinase Receptor TorS
- (2009) Jason O. Moore et al. STRUCTURE
- Sympathetic Activation in Chronic Renal Failure
- (2008) M. P. Schlaich et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now