IMAC capture of recombinant protein from unclarified mammalian cell feed streams

Baseline carcinoembryonic antigen (CEA) serum levels predict bevacizumab-based treatment response in metastatic colorectal cancer

(2014) Gerald W. Prager et al.   CANCER SCIENCE

Identification and characterization of host cell protein product-associated impurities in monoclonal antibody bioprocessing

(2013) Nicholas E. Levy et al.   BIOTECHNOLOGY AND BIOENGINEERING

Metabolic analysis of antibody producing CHO cells in fed-batch production

(2013) Jason Dean et al.   BIOTECHNOLOGY AND BIOENGINEERING

Evaluation of a novel pneumatic bioreactor system for culture of recombinant Chinese hamster ovary cells

(2013) Jae Choon Kim et al.   BIOTECHNOLOGY AND BIOPROCESS ENGINEERING

Consequences of glycan truncation on Fc structural integrity

(2013) Patrick M Buck et al.   mAbs

Preparative Purification of Recombinant Proteins: Current Status and Future Trends

(2013) Mayank Saraswat et al.   Biomed Research International

Immobilized metal ion affinity chromatography: a review on its applications

(2012) Randy Chi Fai Cheung et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Isotype and glycoform selection for antibody therapeutics

(2012) Roy Jefferis   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

The dynamics of the CHO host cell protein profile during clarification and protein A capture in a platform antibody purification process

(2012) Catherine E.M. Hogwood et al.   BIOTECHNOLOGY AND BIOENGINEERING

Integrated continuous production of recombinant therapeutic proteins

(2012) Veena Warikoo et al.   BIOTECHNOLOGY AND BIOENGINEERING

Recombinant protein expression and purification: A comprehensive review of affinity tags and microbial applications

(2012) Carissa L. Young et al.   Biotechnology Journal

State-of-the-art in downstream processing of monoclonal antibodies: Process trends in design and validation

(2012) P. A. Marichal-Gallardo et al.   BIOTECHNOLOGY PROGRESS

Are axial and radial flow chromatography different?

(2012) Tamara Besselink et al.   JOURNAL OF CHROMATOGRAPHY A

Mammalian cell protein expression for biopharmaceutical production

(2011) Jianwei Zhu   BIOTECHNOLOGY ADVANCES

An overview of enzymatic reagents for the removal of affinity tags

(2011) David S. Waugh   PROTEIN EXPRESSION AND PURIFICATION

Targeting CEA in Pancreas Cancer Xenografts with a Mutated scFv-Fc Antibody Fragment

(2011) Mark D Girgis et al.   EJNMMI Research

Fragmentation of a highly purified monoclonal antibody attributed to residual CHO cell protease activity

(2010) Sharon X. Gao et al.   BIOTECHNOLOGY AND BIOENGINEERING

Production of recombinant proteins by microbes and higher organisms

(2009) Arnold L. Demain et al.   BIOTECHNOLOGY ADVANCES

25 years of recombinant proteins from reactor-grown cells — Where do we go from here?

(2009) David L. Hacker et al.   BIOTECHNOLOGY ADVANCES

Step change in the efficiency of centrifugation through cell engineering: co-expression ofStaphylococcal nucleaseto reduce the viscosity of the bioprocess feedstock

(2009) B. Balasundaram et al.   BIOTECHNOLOGY AND BIOENGINEERING

Engineering complex-type N-glycosylation in Pichia pastoris using GlycoSwitch technology

(2009) Pieter P Jacobs et al.   Nature Protocols

The effects of culture conditions on the glycosylation of secreted human placental alkaline phosphatase produced in Chinese hamster ovary cells

(2008) Jong Hyun Nam et al.   BIOTECHNOLOGY AND BIOENGINEERING

Fluorophore-conjugated anti-CEA Antibody for the Intraoperative Imaging of Pancreatic and Colorectal Cancer

(2008) Sharmeela Kaushal et al.   JOURNAL OF GASTROINTESTINAL SURGERY

Shaken, Not Stirred: Mechanical Stress Testing of an IgG1 Antibody

(2008) Sylvia Kiese et al.   JOURNAL OF PHARMACEUTICAL SCIENCES