Genetically engineered proteins with two active sites for enhanced biocatalysis and synergistic chemo- and biocatalysis
出版年份 2019 全文链接
标题
Genetically engineered proteins with two active sites for enhanced biocatalysis and synergistic chemo- and biocatalysis
作者
关键词
-
出版物
Nature Catalysis
Volume -, Issue -, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2019-12-17
DOI
10.1038/s41929-019-0394-4
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Rational Engineering of Multiple Active Sites in an Ester Hydrolase
- (2018) Gerard Santiago et al. BIOCHEMISTRY
- Rational redesign of the active site of selenosubtilisin with strongly enhanced glutathione peroxidase activity
- (2018) Tingting Wang et al. JOURNAL OF CATALYSIS
- A Rational Active-Site Redesign Converts a Decarboxylase into a C═C Hydratase: “Tethered Acetate” Supports Enantioselective Hydration of 4-Hydroxystyrenes
- (2018) Stefan E. Payer et al. ACS Catalysis
- Engineered Biomolecular Catalysts
- (2017) Kara L. Bren JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Adaptive simulations, towards interactive protein-ligand modeling
- (2017) Daniel Lecina et al. Scientific Reports
- Directed evolution of artificial metalloenzymes for in vivo metathesis
- (2016) Markus Jeschek et al. NATURE
- An artificial metalloenzyme with the kinetics of native enzymes
- (2016) P. Dydio et al. SCIENCE
- Rational Enzyme Engineering Through Biophysical and Biochemical Modeling
- (2016) Sandra Acebes et al. ACS Catalysis
- Synthesis of a heterogeneous artificial metallolipase with chimeric catalytic activity
- (2015) M. Filice et al. CHEMICAL COMMUNICATIONS
- Artificial metalloenzymes derived from three-helix bundles
- (2015) Alison G Tebo et al. CURRENT OPINION IN CHEMICAL BIOLOGY
- New Tricks for Old Proteins: Single Mutations in a Nonenzymatic Protein Give Rise to Various Enzymatic Activities
- (2015) Yurii S. Moroz et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Histidine Orientation Modulates the Structure and Dynamics of a de Novo Metalloenzyme Active Site
- (2015) Matthew R. Ross et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Novel artificial metalloenzymes by in vivo incorporation of metal-binding unnatural amino acids
- (2015) Ivana Drienovská et al. Chemical Science
- Short peptides self-assemble to produce catalytic amyloids
- (2014) Caroline M. Rufo et al. Nature Chemistry
- De Novo Design of an Artificial Bis[4Fe-4S] Binding Protein
- (2013) Anindya Roy et al. BIOCHEMISTRY
- Influence of Active Site Location on Catalytic Activity in de Novo-Designed Zinc Metalloenzymes
- (2013) Melissa L. Zastrow et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Precision is essential for efficient catalysis in an evolved Kemp eliminase
- (2013) Rebecca Blomberg et al. NATURE
- Elementary tetrahelical protein design for diverse oxidoreductase functions
- (2013) Tammer A Farid et al. Nature Chemical Biology
- Artificial Metalloenzymes and Metallopeptide Catalysts for Organic Synthesis
- (2013) Jared C. Lewis ACS Catalysis
- Enantioselective Artificial Metalloenzymes by Creation of a Novel Active Site at the Protein Dimer Interface
- (2012) Jeffrey Bos et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Catalysis by a De Novo Zinc-Mediated Protein Interface: Implications for Natural Enzyme Evolution and Rational Enzyme Engineering
- (2012) Bryan S. Der et al. BIOCHEMISTRY
- Computational Design of Catalytic Dyads and Oxyanion Holes for Ester Hydrolysis
- (2012) Florian Richter et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Computational redesign of a mononuclear zinc metalloenzyme for organophosphate hydrolysis
- (2012) Sagar D Khare et al. Nature Chemical Biology
- Diminishing returns and tradeoffs constrain the laboratory optimization of an enzyme
- (2012) Nobuhiko Tokuriki et al. Nature Communications
- Optimization of the In-Silico-Designed Kemp Eliminase KE70 by Computational Design and Directed Evolution
- (2011) Olga Khersonsky et al. JOURNAL OF MOLECULAR BIOLOGY
- Hydrolytic catalysis and structural stabilization in a designed metalloprotein
- (2011) Melissa L. Zastrow et al. Nature Chemistry
- Kemp elimination catalysts by computational enzyme design
- (2008) Daniela Röthlisberger et al. NATURE
- De Novo Computational Design of Retro-Aldol Enzymes
- (2008) L. Jiang et al. SCIENCE
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationPublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More