Article
Engineering, Chemical
Ana Todorovic, Luka Sturm, Ana Salevic-Jelic, Steva Levic, Ilja Gasan Osojnik Crnivec, Iztok Prislan, Mihaela Skrt, Ana Bjekovic, Natasa Poklar Ulrih, Viktor Nedovic
Summary: This study aimed to encapsulate anthocyanin-rich bilberry extract using freeze-drying and investigate the effects of different wall materials and extract contents on the properties of the encapsulates. The use of maltodextrin provided the best protection to the anthocyanins. The obtained encapsulates have potential for the development of food products with added nutritional benefits.
Review
Agricultural Engineering
Asmaa Al-Hamayda, Basim Abu-Jdayil, Mutamed Ayash, Joy Tannous
Summary: Natural gums are commonly used in various industries as stabilizers, thickeners, gelling agents, and emulsifiers. They can also act as carriers for food additives and have good barrier characteristics. Microencapsulation, especially spray drying, is an effective technique for improving the dispersion of bioactive substances in food. Arabic gum is an effective and safe antimicrobial and antioxidant additive in food, but its utility in the industrial encapsulation process is currently limited.
INDUSTRIAL CROPS AND PRODUCTS
(2023)
Article
Engineering, Chemical
Monchawan Wangkulangkool, Danupol Ketthaisong, Ratchada Tangwongchai, Thidarut Boonmars, Khomsorn Lomthaisong
Summary: Encapsulation using whey protein and gum arabic as wall materials was used to protect chia oil from oxidation. The spray-drying and freeze-drying methods produced microcapsules with different powder characteristics. Microcapsules produced by spray drying had higher encapsulation efficiency compared to freeze drying. After 6 months of storage, the encapsulated powders had low acid and peroxide values, suggesting a successful encapsulation process to protect chia oil from oxidation.
Article
Biochemistry & Molecular Biology
Eloize Silva Alves, Cintia Stefhany Ripke Ferreira, Paulo Ricardo Souza, Andressa Rafaella Silva Bruni, Matheus Campos Castro, Bruno Henrique Figueiredo Saqueti, Oscar Oliveira Santos, Grasiele Scaramal Madrona, Jesui Vergilio Visentainer
Summary: This study investigated the effects of maltodextrin and gum arabic on freeze-dried human milk (HM), aiming to improve its quality and solubility. The results showed that both coatings led to higher solubility and better stabilization of HM, with gum arabic demonstrating superior performance. The combination of gum arabic and maltodextrin also showed promising results, indicating their potential synergistic effects.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Engineering, Environmental
Mohamed Abdin, Mohamed Abdelbaset Salama, R. M. A. Gawad, Mohamed Ahmed Fathi, Fawze Alnadari
Summary: An efficient method based on encapsulation efficiency of Syzygium cumini anthocyanin extract was established using stable concentration of the extract and sodium alginate, interacting with different concentrations of maltodextrin, gum Arabic, and chitosan as carriers. The study found that the SA and CH particles had a surface like-sheet structure with high encapsulation efficiency and unique peaks in Fourier transform-infrared spectroscopy. Additionally, the SA and GA particles showed reduced degradation rate of the extract compared to other particles, with no significant differences in color properties during storage days.
JOURNAL OF POLYMERS AND THE ENVIRONMENT
(2021)
Article
Chemistry, Physical
Miki Kadowaki, Tsutashi Matsuura, Hiroyuki Imanaka, Naoyuki Ishida, Koreyoshi Imamura
Summary: This study found that gum arabic is an ideal substance to prevent aggregation of Au nanoparticles during freeze-thawing and freeze-drying at low concentrations. Surface enhanced infrared spectroscopic analysis showed that gum arabic molecules were concentrated in the unfrozen liquid on the Au coating in the frozen state, while carboxylic groups in gum arabic molecules became closer to the Au surface in the freeze-dried state. Due to its high thickening property, gum arabic plays an important role in minimizing the aggregation of AuNPs during freeze-thawing, and the freeze-dried gum arabic forms a rigid amorphous matrix with an affinity for the Au surface, resulting in the inhibition of aggregation.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2022)
Article
Chemistry, Applied
Mahmood Alizadeh-Sani, Milad Tavassoli, David Julian McClements, Hamed Hamishehkar
Summary: A novel multifunctional halochromic packaging material was developed by immobilizing saffron petal anthocyanins within a biopolymer matrix, showing potential applications in food packaging. The color of the films changed depending on pH and ammonia gas levels, providing visual color-changing properties.
FOOD HYDROCOLLOIDS
(2021)
Article
Chemistry, Applied
Linyuan Liu, Duoduo Zhang, Xiaoxiao Song, Mi Guo, Ziwei Wang, Fang Geng, Xingtao Zhou, Shaoping Nie
Summary: In this study, the encapsulation of anthocyanins with Gelatin/Gellan gum was investigated to protect anthocyanins from degradation in the stomach and enhance their release in the small intestine. The results showed that Gelatin/Gellan gum = 8/2 had the most compact and stable structure, and the compound hydrogels did not inhibit the proliferation of normal rat intestinal epithelial cells (IEC-6), indicating the effectiveness and safety of this method.
FOOD HYDROCOLLOIDS
(2022)
Article
Food Science & Technology
Siyi Peng, Jiajia Zhao, Yaru Wang, Fang Chen, Xiaosong Hu, Lingjun Ma, Junfu Ji
Summary: In this study, the stability of L-menthol was improved by microencapsulation and different powder drying techniques were compared. The best results were obtained by using a mass ratio of 2:1 (alpha-LA: GA) and drying the microencapsulated particles using non-thermal spray freeze drying (SFD). The SFD particles had a spherical and porous structure with the highest porosity (86.82%) and showed enhanced flavor retention during high humidity storage. The porous structure of SFD powders also allowed rapid rehydration and the release of L-menthol followed Fickian diffusion.
FOOD RESEARCH INTERNATIONAL
(2023)
Article
Engineering, Chemical
Ulas Baysan, Asli Zungur Bastioglu, Necmiye Oznur Coskun, Dilara Konuk Takma, Eda Ulkeryildiz Balcuk, Hilal Sahin-Nadeem, Mehmet Koc
Summary: This study investigated the effects of coating materials on encapsulated propolis using spray and freeze drying methods. The emulsion properties influenced the physical and chemical properties of the final product, which varied depending on the encapsulation method and coating materials used. The freeze drying method showed higher product yield compared to spray drying, with encapsulation efficiency consistently above 95% in both drying methods, indicating effective encapsulation processes.
Article
Food Science & Technology
Kritika Buranachokpaisan, Rattana Muangrat
Summary: Oil extracted from pressed sesame seed cake using supercritical CO2 can be encapsulated into microcapsules through coacervation and subsequent spray drying or freeze drying methods. The microcapsule wall materials consist of a mixture of gum arabic and gelatin or whey protein isolate at different weight ratios and pH levels. Freeze drying with a ratio of 1:1 of whey protein isolate to gum arabic at pH 3.5 achieved the highest encapsulation efficiency (>70%) and resulted in high content of sesamin, sesamolin, and tocopherols in the encapsulated oil powder. The commercial wall material SYLOID (R) 244FP also showed high encapsulation efficiency (79.93%) and resulted in similar high content of bioactive compounds in the encapsulated oil powder.
FOOD AND BIOPROCESS TECHNOLOGY
(2023)
Article
Pharmacology & Pharmacy
Marija Banozic, Malgorzata Krzywonos, Krunoslav Aladic, Hanna Pinkowska, Igor Mucha, Adrianna Zlocinska, Stela Jokic
Summary: This study evaluated the encapsulation of hesperidin using freeze drying and spray drying techniques with maltodextrin and gum arabic. The results showed that these encapsulation techniques significantly improved the solubility and stability of hesperidin, while also enhancing its flow properties.
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
(2023)
Article
Chemistry, Applied
Sina Makouie, Mohammad Alizadeh, Omid Maleki, Asghar Khosrowshahi
Summary: By using freeze-drying technology and a mixture of whey protein isolate, Arabic gum, and Zedo gum, microencapsulation of Nigella sativa seed oil can produce samples with optimal characteristics. The study showed that lower particle size and better dispersion can be achieved by adding more Arabic gum and whey protein isolate.
FLAVOUR AND FRAGRANCE JOURNAL
(2021)
Article
Food Science & Technology
Hamid Gharanjig, Marjan Iri, Mozhgan Hosseinnezhad, Kamaladin Gharanjig, Seid Mahdi Jafari
Summary: An optimum concentration of Angum gum and cress seed gum enhanced the thermal stability of anthocyanins from black barberry. The presence of SF-AG and CSG in their optimum concentration improved the heat stability of anthocyanin extract. Moreover, physical molecular bondings were observed and plateau or flake-like micro-particles were detected.
JOURNAL OF FOOD SCIENCE
(2022)
Article
Biochemistry & Molecular Biology
Aleksandra A. Jovanovic, Steva M. Levic, Vladimir B. Pavlovic, Smilja B. Markovic, Rada V. Pjanovic, Verica B. Dordevic, Viktor Nedovic, Branko M. Bugarski
Summary: The study compared freeze drying and spray drying for processing wild thyme drugs, finding that freeze drying was more effective in terms of total powder yield and polyphenol content. Gelatin as a coating agent improved TPC recovery and reduced material deposition on the drying chamber wall, leading to differences in polyphenol content in the resulting powders.
Review
Food Science & Technology
Shahida Anusha Siddiqui, Nur Alim Bahmid, Ahmed Taha, Ibrahim Khalifa, Sipper Khan, Hadis Rostamabadi, Seid Mahdi Jafari
Summary: The importance of a healthy diet in well-being has led to a growing interest in designing functional food products enriched with biologically active molecules. Polyphenolic compounds (phenolics), as nature-inspired bioactive components, have been found to have potential in medical interventions. However, the limitations in their application in the food industry, such as instability, poor solubility, and low bioavailability, can be overcome with advances in encapsulation technology.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Article
Chemistry, Applied
Saeid Jafari, Seid Mahdi Jafari, Mahdi Ebrahimi, Isaya Kijpatanasilp, Kitipong Assatarakul
Summary: This article summarizes the findings of almost 70 studies on spray drying encapsulation of fruit products over the last decade. The composition and type of carriers were found to be important in maintaining the physicochemical, structural, and functional aspects of microcapsules. Bioactive-microcapsules have shown promising results in food products for enrichment, fortification, coloring, and stability enhancement, but further research is needed to ensure low toxicity and improved bioaccessibility. Spray drying encapsulation of bioactive compounds in fruit products could provide new possibilities for controlled delivery of beneficial compounds and prevention or treatment of a wide range of diseases.
FOOD HYDROCOLLOIDS
(2023)
Article
Chemistry, Physical
Hashem Andishmand, Sodeif Azadmard-damirchi, Hamed Hamishekar, MoammadAli Torbati, Mohammad Saeed Kharazmi, Geoffrey P. Savage, Chen Tan, Seid Mahdi Jafari
Summary: Pomegranate peel, a main byproduct of pomegranate fruit, contains rich phenolic compounds with antioxidant, antimicrobial, and health effects. This article reviews recent advancements in the design and fabrication of nano-delivery systems for pomegranate peel bioactive compounds, focusing on lipid-based nanocarriers such as solid lipid nanoparticles, nanostructured lipid carriers, and vesicular nanocarriers. These lipid-based nanocarriers have low toxicity, large-scale production feasibility, easy synthesis, and high biocompatibility, making them a promising approach for enhancing the quality, safety, shelf life, and health benefits of pomegranate products.
ADVANCES IN COLLOID AND INTERFACE SCIENCE
(2023)
Article
Chemistry, Physical
Chen Tan, Yuqian Zhu, Hamed Ahari, Seid Mahdi Jafari, Baoguo Sun, Jing Wang
Summary: Sonochemistry has potential in synthesizing or modifying new micro/nanomaterials, especially in the production of cross-linked emulsions for drug delivery. However, the use of sonochemical emulsions for delivering bioactive compounds from food sources is still at an early stage. Expanding the use of sonochemistry as a tool for engineering bioactive delivery systems will make the approach more versatile and increase its applications in the food industry.
ADVANCES IN COLLOID AND INTERFACE SCIENCE
(2023)
Article
Chemistry, Physical
P. Barciela, M. Carpena, Ning-Yang Li, Chao Liu, S. M. Jafari, J. Simal-Gandara, M. A. Prieto
Summary: Nanotechnology has opened a new frontier in the food industry by providing new ways of controlling and structuring products with greater market value, especially in areas such as food processing, preservation, and packaging. Macroalgae have been recognized as a potential source of secondary metabolites, such as phenolic compounds, pigments, and polysaccharides, which can be used for biosynthesis of metal nanoparticles (NPs). These biosynthesized metal NPs derived from macroalgae show advantages in terms of cost, production time, and biocompatibility, making them suitable for various applications in the food industry, such as nanoencapsulation, nanocomposites, and biosensors. However, the potential toxicity of metal NPs should be considered, and applicable regulations need to ensure their safe use.
ADVANCES IN COLLOID AND INTERFACE SCIENCE
(2023)
Article
Chemistry, Physical
Mohammadreza Rostami, Nima Beheshtizadeh, Faezeh Esmaeili Ranjbar, Nahid Najafi, Azam Ahmadi, Parisa Ahmadi, Hadis Rostamabadi, Zahra Pazhouhnia, Elham Assadpour, Mina Mirzanajafi-Zanjani, Misagh Fathi Kisomi, Mohammad Saeed Kharazmi, Seid Mahdi Jafari
Summary: Electrospinning is a convenient, adaptive, and scalable technique for manufacturing nano/micro/macro-fibers. Protein-based electrospun fibers have desirable properties such as biocompatibility, low toxicity, degradability, and solvolysis. This paper provides an overview of protein-based biomaterials and their potential for electrospinning. It also showcases the applications of electrospun protein fibers in the food and biomedical industries and discusses the future prospects and challenges they present.
ADVANCES IN COLLOID AND INTERFACE SCIENCE
(2023)
Review
Chemistry, Multidisciplinary
Milad Hadidi, Chen Tan, Elham Assadpour, Mohammad Saeed Kharazmi, Seid Mahdi Jafari
Summary: The high prevalence of chronic illnesses has become a concern, and bioactive compounds have shown potential as health-enhancing substances. However, their application is limited due to solubility and bioavailability issues. Plant proteins have emerged as green alternatives for designing nanocarriers, offering compatibility with bioactives and unique functional properties. Recent studies have demonstrated the use of emerging plant proteins as nanocarriers for protection and delivery of bioactives. These proteins can improve solubility, stability, and bioavailability, especially when combined with other biopolymers. This review covers the sources and importance of plant proteins, encapsulation techniques, and their application as nanocarriers for food bioactives.
JOURNAL OF CONTROLLED RELEASE
(2023)
Article
Food Science & Technology
Khashayar Sarabandi, Alireaza Dashipour, Zahra Izadi, Zahra Akbarbaglu, Iman Katouzian, Seid Mahdi Jafari
Summary: The study investigated the composition of proteins and hydrolysates of bellflower, Persian willow, and bitter orange under the influence of different proteases. The results showed that flower pollen contains amide regions and secondary structures, and is rich in hydrophobic amino acids, antioxidants, and essential types. The hydrolyzed samples had higher digestibility and nutritional quality than the original protein. The inhibition of free radicals and the growth of bacteria were affected by protein type and enzyme, indicating that hydrolyzed flower pollens can be used as natural antioxidants and antibacterial agents in food and dietary products.
JOURNAL OF FOOD SCIENCE
(2023)
Article
Food Science & Technology
Alireza Sadeghi, Maryam Ebrahimi, Mohammad Saeed Kharazmi, Seid Mahdi Jafari
Summary: There is a growing interest in using next-generation probiotics (NGPs) combined with nanomaterials (NMs) for targeted delivery and improved functionality in food and pharmaceutical products. NMs as carriers or coatings have pivotal importance in the applications of NGPs. However, potential inhibitory effects, interactions with food components, and concerns about toxicity and biosafety need to be considered. This review highlights recent studies on the capabilities of NMs to enhance the functionalities of NGPs for innovative applications.
Article
Food Science & Technology
Khashayar Sarabandi, Maryam Mohammadi, Zahra Akbarbaglu, Marjan Ghorbani, Shahla Najafi, Sara Safaeian Laein, Seid Mahdi Jafari
Summary: The effect of enzymatic hydrolysis of apricot kernel protein with different proteases on the amino acid content, degree of hydrolysis, antioxidant, and antibacterial characteristics of the resulting hydrolyzates was investigated. The study showed that the hydrolyzates had high digestibility and can serve as a source of nutrients and antioxidants. The type of enzyme used affected the solubility, water- and oil-holding capacity, and various antioxidant and antibacterial activities.
FOOD SCIENCE & NUTRITION
(2023)
Article
Food Science & Technology
Sanaz Ghasemi, Elham Assadpour, Mohammad Saeed Kharazmi, Shima Jafarzadeh, Masoumeh Zargar, Seid Mahdi Jafari
Summary: Orange peel oil (OPO) was encapsulated within biopolymer nanocomposites to improve its bioavailability and stability. The encapsulation efficiency was in the range of 70-88%, and the nanoscale size of the particles was confirmed. The release profile of OPO differed under different pH and temperature conditions, with the Higuchi model providing the best fit to the experimental data. The encapsulated OPO showed promising characteristics for food flavoring applications.
Review
Chemistry, Medicinal
Elham Assadpour, Atefe Rezaei, Sabya Sachi Das, Balaga Venkata Krishna Rao, Sandeep Kumar Singh, Mohammad Saeed Kharazmi, Niraj Kumar Jha, Saurabh Kumar Jha, Miguel A. A. Prieto, Seid Mahdi Jafari
Summary: Researchers have developed nanocarriers to enhance the oral bioavailability of Cannabidiol (CBD), improving its therapeutic efficacy and ability to treat various diseases.
Review
Chemistry, Physical
Shahida Anusha Siddiqui, Shubhra Singh, Nur Alim Bahmid, Taha Mehany, Douglas J. H. Shyu, Elham Assadpour, Narjes Malekjani, Roberto Castro-Munoz, Seid Mahdi Jafari
Summary: This paper systematically analyzes the identification of original articles using Scopus and Google Scholar on active packaging as a novel technology for controlling the release of antimicrobial agents in food packaging systems. The encapsulation of bioactives enhances their bioavailability and stability, and mathematical models play an important role in understanding and predicting their release behavior during transportation and storage. However, few studies have formulated parameters for mathematical models to achieve specific release mechanisms for the quality and safety of foods.
COLLOIDS AND INTERFACES
(2023)
Article
Food Science & Technology
Danial Dehnad, Bahareh Emadzadeh, Behrouz Ghorani, Ghadir Rajabzadeh, Seid Mahdi Jafari
Summary: This research comprehensively studied the characteristics of high hydrostatic pressure-treated soy protein isolate solutions and electrospun fibers. High hydrostatic pressure treatment resulted in smaller fiber size, reduced crystallinity, increased melting point, and the formation of hydrogen bonds between denatured soy protein isolate and polyvinyl alcohol.
Article
Pharmacology & Pharmacy
Mohammad Yousefi, Seid Mahdi Jafari, Hossein Ahangari, Ali Ehsani
Summary: The study investigated the effects of nanoliposomes containing crocin and nisin in milk samples. Three formulations were prepared and compared, and the optimal formulation was found to contain 4 mg crocin, 4.5 mg nisin, and 40 mg lecithin. The nanoliposomes showed promising results in reducing redness and inhibiting bacterial growth in milk.
ADVANCED PHARMACEUTICAL BULLETIN
(2023)
Review
Chemistry, Applied
Xingran Kou, Dongdong Su, Fei Pan, Xiwei Xu, Qingran Meng, Qinfei Ke
Summary: This review provides a systematic discussion of the application of molecular dynamics (MD) simulations in aroma compounds (ACs)/cyclodextrins (CDs) inclusion complexes (ICs). It covers the establishment of the simulation process, parameter selection, model evaluation, and various application cases, summarizing the major achievements and challenges of this method.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Haoyu Yu, Quanbin Zhang, Ammad Ahmad Farooqi, Jing Wang, Yang Yue, Lihua Geng, Ning Wu
Summary: Brown algae are rich in fucoidan, which has been found to have anti-cancer and anti-metastasis effects. Fucoidan inhibits tumor cell growth, proliferation, and metastasis, and also promotes immune responses in the tumor microenvironment.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Liang Dong, Yanan Li, Hailin Cong, Bing Yu, Youqing Shen
Summary: Gene therapy is a revolutionary treatment that requires suitable vectors for protecting and releasing exogenous nucleic acids in target cells. Chitosan, as a non-viral vector, has gained attention due to its good biocompatibility and ability to load large amounts of nucleic acids. This paper summarizes the potential of chitosan and its derivatives as gene delivery vector materials, discusses factors influencing transfection efficiency, performance evaluation, ways to optimize infectious efficiency, and current research development directions. It also provides an outlook on the future prospects of chitosan.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ana Iglesias-Mejuto, Beatriz Magarinos, Tania Ferreira-Goncalves, Ricardo Starbird-Perez, Carmen Alvarez-Lorenzo, Catarina Pinto Reis, Ines Ardao, Carlos A. Garcia-Gonzalez
Summary: This study developed a novel processing strategy to manufacture drug-loaded and personalized aerogels with nanostructures. The aerogels demonstrated bioactivity and antimicrobial effects, promoting bone regeneration and preventing infections in bone tissue engineering.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Zhenxu Shi, Dimei Yang, Yan Zhou, Xinyu Chen, Lin Gan, Jin Huang
Summary: This study proposes a micro-assembly method to improve the photoluminescent properties of crystalline cellulose nanocrystals (CNCs) by organizing them within a sub-micrometer-sized metal-organic framework and coating with TiO2. The TiO2 coating prevents CNC assembly breakdown and allows information to be revealed using screenprinted labels for anti-counterfeiting purposes.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Xuejiao Liu, Bin Fu, Jierong Chen, Zhenyu Sun, Dongdong Zheng, Zhonghua Li, Bing Gu, Ying Zhang, Haojie Lu
Summary: Liver disease is a major cause of global mortality, and identifying biomarkers for diagnosing its progression is crucial for improving outcomes. Targeted mass spectrometry is a powerful tool for verifying biomarker candidates and clinical applications, particularly for glycoproteins translation. However, the limitation of analyzing only one sample per run has become apparent. In this study, a high-throughput intact N-glycopeptides quantification strategy was developed, allowing the validation of 20 samples per run with an average analysis time of 3 minutes per sample. The strategy was applied in a cohort of 461 serum samples and identified a panel of 10 IgG N-glycopeptides that have strong clinical utility in evaluating the severity of liver disease.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Qian Wang, Hao Jiang, Hongli Zhang, Weiqiao Lu, Xiao Wang, Wenfeng Xu, Jia Li, Youjing Lv, Guoyun Li, Chao Cai, Guangli Yu
Summary: This study proposes a novel strategy of antibody-beta-glucan conjugates (AGC) to enhance the antitumor immune response to immune checkpoint blockade (ICB) therapy. AGC demonstrated powerful tumor suppression and promoted interaction between tumor cells and dendritic cells (DCs), thereby enhancing immunotherapeutic benefits.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Chaeyeon Lee, Sojeong Lee, Sang Wook Kang
Summary: The study aims to enhance the properties of porous membranes by addressing the limitations associated with phase separation. By using cellulose acetate and citric acid, the researchers were able to fabricate membranes with improved mechanical strength and thermal stability. The cross-linking effect of citric acid resulted in a more uniform pore structure and higher porosity.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Tejaswini Kolipaka, Giriraj Pandey, Noella Abraham, Dadi A. Srinivasarao, Rajeev Singh Raghuvanshi, P. S. Rajinikanth, Vidya Tickoo, Saurabh Srivastava
Summary: This review focuses on the design and application of polysaccharide-based hydrogel wound dressings, highlighting aspects such as biocompatibility, biodegradability, drug entrapment, moisturizing ability, swelling, and mechanical properties. Additionally, various crosslinking methods and recent developments in stimuli-responsive hydrogels are discussed.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Anqi Xu, Nan Zhang, Shixing Su, Hongyu Shi, Daoqiang Lu, Xifeng Li, Xin Zhang, Xin Feng, Zhuohua Wen, Gengwu Ma, Mengshi Huang, Chi Huang, Yuqi Hu, Hao Yuan, Qinwen Liu, Daogang Guan, Jun Wang, Chuanzhi Duan
Summary: The study presents a one-pot radical polymerization method to fabricate a hydrogel with adhesive properties, which can effectively treat bacterial-infected diabetic wounds and accelerate wound healing.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Montarop Yamabhai, Munthipha Khamphio, Thae Thae Min, Chai Noy Soem, Nguyen Cao Cuong, Waheni Rizki Aprilia, Krisanai Luesukprasert, Karsidete Teeranitayatarn, Atthaphon Maneedaeng, Tina R. Tuveng, Silje B. Lorentzen, Simen Antonsen, Paiboon Jitprasertwong, Vincent G. H. Eijsink
Summary: The study investigates the bioconversion of chitosan into soluble anti-inflammatory chitosan oligosaccharides (CHOS) using an enzyme. The results show that the generated CHOS have anti-inflammatory activity, but the magnitude of the activity depends on the substrate and production process. Different methods of dissolving chitosan also affect the properties of CHOS. The study highlights the importance of quality assurance in CHOS preparations.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Wen Cao, Jiangping Wu, Xinya Zhao, Zixu Li, Jie Yu, Taili Shao, Xuefeng Hou, Lutan Zhou, Chunfei Wang, Guodong Wang, Jun Han
Summary: In this study, a water-soluble polysaccharide (PLP1) was successfully isolated and purified from Pueraria lobata. It was found that PLP1 was composed of specific glycosidic units and exhibited a better free radical-scavenging ability. Moreover, PLP1 effectively protected the liver against acute alcoholic liver disease (ALD) in mice.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ya Su, Yaqian Liu, Xueyan Hu, Yueqi Lu, Jinyuan Zhang, Wenbo Jin, Wang Liu, Yan Shu, Yuen Yee Cheng, Wenfang Li, Yi Nie, Bo Pan, Kedong Song
Summary: A 3D printed scaffold based on carbon dots-curcumin nano-drug release has been developed for drug delivery after breast cancer surgery. The scaffold showed effective inhibition of tumor growth, antibacterial activity, and promotion of wound healing, making it a promising approach for preventing tumor recurrence.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ekaterina Sokolova, Diane Jouanneau, Antonin Chevenier, Murielle Jam, Nathalie Desban, Pierre Colas, Elizabeth Ficko-Blean, Gurvan Michel
Summary: Carrageenans, a compound synthesized in red algae, have various biological properties and are valuable in the pharmaceutical and cosmetic industries. Their fine structure affects wound healing, oxidative processes, hemostasis, and inflammation. Enzymatic modification of carrageenans produces oligosaccharides that bind to natural human serum antibodies and specific antibodies, showing potential for therapeutic applications.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Yan Shi, Miao Yu, Kaijin Qiu, Tiantian Kong, Chunjing Guo, Wenxue Zhang, Daquan Chen, Ming Kong
Summary: In this study, functionalized transfersomes were developed to co-deliver doxorubicin and 1MT towards primary tumors and tumor draining lymph nodes via transdermal administration using microneedles. The results showed that the nano-complexed microneedles exhibited a stronger suppression in tumor growth compared to the intravenous group.
CARBOHYDRATE POLYMERS
(2024)
