Is Lactate an Oncometabolite? Evidence Supporting a Role for Lactate in the Regulation of Transcriptional Activity of Cancer-Related Genes in MCF7 Breast Cancer Cells
出版年份 2020 全文链接
标题
Is Lactate an Oncometabolite? Evidence Supporting a Role for Lactate in the Regulation of Transcriptional Activity of Cancer-Related Genes in MCF7 Breast Cancer Cells
作者
关键词
-
出版物
Frontiers in Oncology
Volume 9, Issue -, Pages -
出版商
Frontiers Media SA
发表日期
2020-01-14
DOI
10.3389/fonc.2019.01536
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- How do mutations affecting the breast cancer genes BRCA1 and BRCA2 cause cancer susceptibility?
- (2019) Ashok R. Venkitaraman DNA REPAIR
- Metabolic regulation of gene expression by histone lactylation
- (2019) Di Zhang et al. NATURE
- Glutamine blockade induces divergent metabolic programs to overcome tumor immune evasion
- (2019) Robert D. Leone et al. SCIENCE
- Lactate-mediated epigenetic reprogramming regulates formation of human pancreatic cancer-associated fibroblasts
- (2019) Tushar D Bhagat et al. eLife
- Do the associations of sedentary behaviour with cardiovascular disease mortality and cancer mortality differ by physical activity level? A systematic review and harmonised meta-analysis of data from 850 060 participants
- (2018) Ulf Ekelund et al. BRITISH JOURNAL OF SPORTS MEDICINE
- The Science and Translation of Lactate Shuttle Theory
- (2018) George A. Brooks Cell Metabolism
- Expression and mutations of BRCA in breast cancer and ovarian cancer: Evidence from bioinformatics analyses
- (2018) Zhu Wang et al. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- Somatic mutant clones colonize the human esophagus with age
- (2018) Iñigo Martincorena et al. SCIENCE
- A metabolic core model elucidates how enhanced utilization of glucose and glutamine, with enhanced glutamine-dependent lactate production, promotes cancer cell growth: The WarburQ effect
- (2017) Chiara Damiani et al. PLoS Computational Biology
- Limits of aerobic metabolism in cancer cells
- (2017) Jorge Fernandez-de-Cossio-Diaz et al. Scientific Reports
- Reexamining cancer metabolism: lactate production for carcinogenesis could be the purpose and explanation of the Warburg Effect
- (2016) Iñigo San-Millán et al. CARCINOGENESIS
- KRAS, BRAF, and PIK3CA mutations, and patient prognosis in 126 pancreatic cancers: pyrosequencing technology and literature review
- (2016) Lei Zhou et al. MEDICAL ONCOLOGY
- Effects of BRCA1- and BRCA2-Related Mutations on Ovarian and Breast Cancer Survival: A Meta-analysis
- (2014) Q. Zhong et al. CLINICAL CANCER RESEARCH
- Antitumor Activity of 7-Aminocarboxycoumarin Derivatives, a New Class of Potent Inhibitors of Lactate Influx but Not Efflux
- (2014) N. Draoui et al. MOLECULAR CANCER THERAPEUTICS
- The PI3K/AKT/mTOR pathway in breast cancer: targets, trials and biomarkers
- (2014) Elisavet Paplomata et al. Therapeutic Advances in Medical Oncology
- Synthesis and pharmacological evaluation of carboxycoumarins as a new antitumor treatment targeting lactate transport in cancer cells
- (2013) Nihed Draoui et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Blocking Lactate Export by Inhibiting the Myc Target MCT1 Disables Glycolysis and Glutathione Synthesis
- (2013) J. R. Doherty et al. CANCER RESEARCH
- Role of hypoxia-inducible factors in breast cancer metastasis
- (2013) Daniele M Gilkes et al. Future Oncology
- Lactate kinetics at the lactate threshold in trained and untrained men
- (2013) Laurent A. Messonnier et al. JOURNAL OF APPLIED PHYSIOLOGY
- Cancer Genome Landscapes
- (2013) B. Vogelstein et al. SCIENCE
- Exercise tames the wild side of the Myc network: a hypothesis
- (2012) Kishorchandra Gohil et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- The scaffold protein MEK Partner 1 is required for the survival of estrogen receptor positive breast cancer cells
- (2012) Mihaela Marina et al. Cell Communication and Signaling
- Targeting the Lactate Transporter MCT1 in Endothelial Cells Inhibits Lactate-Induced HIF-1 Activation and Tumor Angiogenesis
- (2012) Pierre Sonveaux et al. PLoS One
- Lactate Activates HIF-1 in Oxidative but Not in Warburg-Phenotype Human Tumor Cells
- (2012) Christophe J. De Saedeleer et al. PLoS One
- Ketones and lactate increase cancer cell “stemness,” driving recurrence, metastasis and poor clinical outcome in breast cancer
- (2011) Ubaldo E. Martinez-Outschoorn et al. CELL CYCLE
- Global quantification of mammalian gene expression control
- (2011) Björn Schwanhäusser et al. NATURE
- An Autocrine Lactate Loop Mediates Insulin-Dependent Inhibition of Lipolysis through GPR81
- (2010) Kashan Ahmed et al. Cell Metabolism
- Deciphering the Role of PI3K/Akt/mTOR Pathway in Breast Cancer Biology and Pathogenesis
- (2010) Priscilla F. McAuliffe et al. Clinical Breast Cancer
- Mitochondrial and plasma membrane lactate transporter and lactate dehydrogenase isoform expression in breast cancer cell lines
- (2010) Rajaa Hussien et al. PHYSIOLOGICAL GENOMICS
- Accumulation of driver and passenger mutations during tumor progression
- (2010) I. Bozic et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- MYC-Induced Cancer Cell Energy Metabolism and Therapeutic Opportunities
- (2009) C. V. Dang et al. CLINICAL CANCER RESEARCH
- HIF-1: upstream and downstream of cancer metabolism
- (2009) Gregg L Semenza CURRENT OPINION IN GENETICS & DEVELOPMENT
- Cell-cell and intracellular lactate shuttles
- (2009) George A. Brooks JOURNAL OF PHYSIOLOGY-LONDON
- How is mRNA expression predictive for protein expression? A correlation study on human circulating monocytes
- (2008) Yanfang Guo et al. ACTA BIOCHIMICA ET BIOPHYSICA SINICA
- Roles of p53, Myc and HIF-1 in Regulating Glycolysis — the Seventh Hallmark of Cancer
- (2008) S. J. Yeung et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Expression of BRCA1 protein in breast cancer and its prognostic significance
- (2008) Emad A. Rakha et al. HUMAN PATHOLOGY
- Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice
- (2008) Pierre Sonveaux et al. JOURNAL OF CLINICAL INVESTIGATION
- Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction
- (2008) D. R. Wise et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Become a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get StartedAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started