Gigantol Targets Cancer Stem Cells and Destabilizes Tumors via the Suppression of the PI3K/AKT and JAK/STAT Pathways in Ectopic Lung Cancer Xenografts
出版年份 2019 全文链接
标题
Gigantol Targets Cancer Stem Cells and Destabilizes Tumors via the Suppression of the PI3K/AKT and JAK/STAT Pathways in Ectopic Lung Cancer Xenografts
作者
关键词
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出版物
Cancers
Volume 11, Issue 12, Pages 2032
出版商
MDPI AG
发表日期
2019-12-20
DOI
10.3390/cancers11122032
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Signal Transducer and Activator of Transcription (STATs) Proteins in Cancer and Inflammation: Functions and Therapeutic Implication
- (2019) Chin-Yap Loh et al. Frontiers in Oncology
- PDIA6 modulates apoptosis and autophagy of non-small cell lung cancer cells via the MAP4K1/JNK signaling pathway
- (2019) Yuxin Bai et al. EBioMedicine
- Moscatilin Inhibits Growth of Human Esophageal Cancer Xenograft and Sensitizes Cancer Cells to Radiotherapy
- (2019) Wun-Ke Chen et al. Journal of Clinical Medicine
- Targeting Cancer Stem Cells: A Strategy for Effective Eradication of Cancer
- (2019) Masahiro Shibata et al. Cancers
- Gigantol inhibits Wnt/β-catenin signaling and exhibits anticancer activity in breast cancer cells
- (2018) Shubin Yu et al. BMC Complementary and Alternative Medicine
- Cancer statistics, 2018
- (2018) Rebecca L. Siegel et al. CA-A CANCER JOURNAL FOR CLINICIANS
- STAT3, stem cells, cancer stem cells and p63
- (2018) Michaela Galoczova et al. CELLULAR & MOLECULAR BIOLOGY LETTERS
- Targeting the IL-6/JAK/STAT3 signalling axis in cancer
- (2018) Daniel E. Johnson et al. Nature Reviews Clinical Oncology
- Up-Regulation of PI 3-Kinases and the Activation of PI3K-Akt Signaling Pathway in Cancer Stem-Like Cells Through DNA Hypomethylation Mediated by the Cancer Microenvironment
- (2018) Aung Ko Ko Oo et al. Translational Oncology
- Structure-Based Classification and Anti-Cancer Effects of Plant Metabolites
- (2018) Seong-Ah Shin et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- The Akt/mTOR pathway in cancer stem/progenitor cells is a potential therapeutic target for glioblastoma and neuroblastoma
- (2018) Hisham F. Bahmad et al. Oncotarget
- Gigantol has Protective Effects against High Glucose-Evoked Nephrotoxicity in Mouse Glomerulus Mesangial Cells by Suppressing ROS/MAPK/NF-κB Signaling Pathways
- (2018) Mei-Fen Chen et al. MOLECULES
- Cancer stem cell pipeline flounders
- (2018) Ken Garber NATURE REVIEWS DRUG DISCOVERY
- PANTHER version 14: more genomes, a new PANTHER GO-slim and improvements in enrichment analysis tools
- (2018) Huaiyu Mi et al. NUCLEIC ACIDS RESEARCH
- STRING v11: protein–protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets
- (2018) Damian Szklarczyk et al. NUCLEIC ACIDS RESEARCH
- Gigantol from Dendrobium chrysotoxum Lindl. binds and inhibits aldose reductase gene to exert its anti-cataract activity: An in vitro mechanistic study
- (2017) Jie Wu et al. JOURNAL OF ETHNOPHARMACOLOGY
- Cancer Stem Cell–Suppressing Activity of Chrysotoxine, a Bibenzyl fromDendrobium pulchellum
- (2017) Narumol Bhummaphan et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Cancer stem cells revisited
- (2017) Eduard Batlle et al. NATURE MEDICINE
- The relationship between tumor cell density in the pretreatment biopsy and survival after chemotherapy in OE02 trial esophageal cancer patients.
- (2017) Matthew D. Hale et al. JOURNAL OF CLINICAL ONCOLOGY
- A comparison of Ki-67 counting methods in luminal Breast Cancer: The Average Method vs. the Hot Spot Method
- (2017) Min Hye Jang et al. PLoS One
- Potential Anti-metastasis Natural Compounds for Lung Cancer
- (2016) PITHI CHANVORACHOTE et al. ANTICANCER RESEARCH
- Gigantol Inhibits Epithelial to Mesenchymal Process in Human Lung Cancer Cells
- (2016) Thitita Unahabhokha et al. Evidence-based Complementary and Alternative Medicine
- The MaxQuant computational platform for mass spectrometry-based shotgun proteomics
- (2016) Stefka Tyanova et al. Nature Protocols
- Enrichr: a comprehensive gene set enrichment analysis web server 2016 update
- (2016) Maxim V. Kuleshov et al. NUCLEIC ACIDS RESEARCH
- Gigantol attenuates the proliferation of human liver cancer HepG2 cells through the PI3K/Akt/NF-κB signaling pathway
- (2016) Huanhuan Chen et al. ONCOLOGY REPORTS
- The attenuation of epithelial to mesenchymal transition and induction of anoikis by gigantol in human lung cancer H460 cells
- (2016) Thitita Unahabhokha et al. TUMOR BIOLOGY
- Significance of different response evaluation criteria in predicting progression-free survival of lung cancer with certain imaging characteristics
- (2016) Dengxia Yang et al. Thoracic Cancer
- Gigantol Suppresses Cancer Stem Cell-Like Phenotypes in Lung Cancer Cells
- (2015) Narumol Bhummaphan et al. Evidence-based Complementary and Alternative Medicine
- jvenn: an interactive Venn diagram viewer
- (2014) Philippe Bardou et al. BMC BIOINFORMATICS
- IL-2 Enhances Cervical Cancer Cells Proliferation and JAK3/STAT5 Phosphorylation at Low Doses, While at High Doses IL-2 Has Opposite Effects
- (2014) Arturo Valle-Mendiola et al. CANCER INVESTIGATION
- Gigantol, a Bibenzyl from Dendrobium draconis, Inhibits the Migratory Behavior of Non-Small Cell Lung Cancer Cells
- (2014) Sopanya Charoenrungruang et al. JOURNAL OF NATURAL PRODUCTS
- Alpha-Smooth Muscle Actin (ACTA2) Is Required for Metastatic Potential of Human Lung Adenocarcinoma
- (2013) H. W. Lee et al. CLINICAL CANCER RESEARCH
- Activation of ERK1/2 and Akt is associated with cisplatin resistance in human lung cancer cells
- (2013) Mei Wang et al. JOURNAL OF CHEMOTHERAPY
- Non-small cell lung cancer cells survived ionizing radiation treatment display cancer stem cell and epithelial-mesenchymal transition phenotypes
- (2013) Roberto Gomez-Casal et al. Molecular Cancer
- Development of PI3K/AKT/mTOR Pathway Inhibitors and Their Application in Personalized Therapy for Non–Small-Cell Lung Cancer
- (2012) Vassiliki Papadimitrakopoulou Journal of Thoracic Oncology
- NIH Image to ImageJ: 25 years of image analysis
- (2012) Caroline A Schneider et al. NATURE METHODS
- RNA-Seq analysis in MeV
- (2011) E. A. Howe et al. BIOINFORMATICS
- Changes in Tumor Density in Patients with Advanced Hepatocellular Carcinoma Treated with Sunitinib
- (2011) S. Faivre et al. CLINICAL CANCER RESEARCH
- A new phenanthrenequinone fromDendrobium draconis
- (2011) Boonchoo Sritularak et al. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
- From Cancer Stem Cells to Tumor Maintenance in Melanoma
- (2011) Mizuho Fukunaga-Kalabis et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- JAK1 Activates STAT3 Activity in Non-Small-Cell Lung Cancer Cells and IL-6 Neutralizing Antibodies Can Suppress JAK1-STAT3 Signaling
- (2011) L. Song et al. MOLECULAR CANCER THERAPEUTICS
- Modified RECIST (mRECIST) Assessment for Hepatocellular Carcinoma
- (2010) Riccardo Lencioni et al. SEMINARS IN LIVER DISEASE
- Moscatilin, a bibenzyl derivative from the India orchid Dendrobrium loddigesii, suppresses tumor angiogenesis and growth in vitro and in vivo
- (2009) An-Chi Tsai et al. CANCER LETTERS
- PI3K pathway regulates survival of cancer stem cells residing in the perivascular niche following radiation in medulloblastoma in vivo
- (2008) D. Hambardzumyan et al. GENES & DEVELOPMENT
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