标题
Computational Prediction and Validation of Tumor-Associated Neoantigens
作者
关键词
-
出版物
Frontiers in Immunology
Volume 11, Issue -, Pages -
出版商
Frontiers Media SA
发表日期
2020-01-24
DOI
10.3389/fimmu.2020.00027
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Virus-specific memory T cells populate tumors and can be repurposed for tumor immunotherapy
- (2019) Pamela C. Rosato et al. Nature Communications
- Neoantigen-directed immune escape in lung cancer evolution
- (2019) Rachel Rosenthal et al. NATURE
- Unleashing Type-2 Dendritic Cells to Drive Protective Antitumor CD4+ T Cell Immunity
- (2019) Mikhail Binnewies et al. CELL
- Systemic clinical tumor regressions and potentiation of PD1 blockade with in situ vaccination
- (2019) Linda Hammerich et al. NATURE MEDICINE
- Immunogenic neoantigens derived from gene fusions stimulate T cell responses
- (2019) Wei Yang et al. NATURE MEDICINE
- Mass spectrometry–based identification of MHC-bound peptides for immunopeptidomics
- (2019) Anthony W. Purcell et al. Nature Protocols
- Induction of neoantigen-reactive T cells from healthy donors
- (2019) Muhammad Ali et al. Nature Protocols
- The Antigen Processing and Presentation Machinery in Lymphatic Endothelial Cells
- (2019) Laura Santambrogio et al. Frontiers in Immunology
- T-Scan: A Genome-wide Method for the Systematic Discovery of T Cell Epitopes
- (2019) Tomasz Kula et al. CELL
- MHC-II neoantigens shape tumour immunity and response to immunotherapy
- (2019) Elise Alspach et al. NATURE
- Developing neoantigen-targeted T cell–based treatments for solid tumors
- (2019) Tori N. Yamamoto et al. NATURE MEDICINE
- Neoantigen Dissimilarity to the Self-Proteome Predicts Immunogenicity and Response to Immune Checkpoint Blockade
- (2019) Lee P. Richman et al. Cell Systems
- Immunopeptidomics of colorectal cancer organoids reveals a sparse HLA class I neoantigen landscape and no increase in neoantigens with interferon or MEK-inhibitor treatment
- (2019) Alice Newey et al. Journal for ImmunoTherapy of Cancer
- Population-level distribution and putative immunogenicity of cancer neoepitopes
- (2018) Mary A. Wood et al. BMC CANCER
- Antigen Identification for Orphan T Cell Receptors Expressed on Tumor-Infiltrating Lymphocytes
- (2018) Marvin H. Gee et al. CELL
- T cells specific for post-translational modifications escape intrathymic tolerance induction
- (2018) Bruno Raposo et al. Nature Communications
- A cloning and expression system to probe T cell receptor specificity and assess functional avidity to neoantigens
- (2018) Zhuting Hu et al. BLOOD
- Comprehensive Analysis of Alternative Splicing Across Tumors from 8,705 Patients
- (2018) André Kahles et al. CANCER CELL
- Cancer-Specific Splicing Changes and the Potential for Splicing-Derived Neoantigens
- (2018) Luisa Escobar Hoyos et al. CANCER CELL
- The Partnership for Accelerating Cancer Therapies
- (2018) Rebecca G. Baker et al. CANCER JOURNAL
- Isolation of a Structural Mechanism for Uncoupling T Cell Receptor Signaling from Peptide-MHC Binding
- (2018) Leah V. Sibener et al. CELL
- Whole-exome sequencing capture kit biases yield false negative mutation calls in TCGA cohorts
- (2018) Victor G. Wang et al. PLoS One
- Biological Consequences of Major Histocompatibility Class-II Expression by Tumor Cells in Cancer
- (2018) Margaret L Axelrod et al. CLINICAL CANCER RESEARCH
- Actively personalized vaccination trial for newly diagnosed glioblastoma
- (2018) Norbert Hilf et al. NATURE
- Neoantigen vaccine generates intratumoral T cell responses in phase Ib glioblastoma trial
- (2018) Derin B. Keskin et al. NATURE
- Publisher Correction: Robust prediction of response to immune checkpoint blockade therapy in metastatic melanoma
- (2018) Noam Auslander et al. NATURE MEDICINE
- Dendritic Cells but Not Macrophages Sense Tumor Mitochondrial DNA for Cross-priming through Signal Regulatory Protein α Signaling
- (2017) Meng Michelle Xu et al. IMMUNITY
- Mass Spectrometry Profiling of HLA-Associated Peptidomes in Mono-allelic Cells Enables More Accurate Epitope Prediction
- (2017) Jennifer G. Abelin et al. IMMUNITY
- Guidelines for Validation of Next-Generation Sequencing–Based Oncology Panels
- (2017) Lawrence J. Jennings et al. JOURNAL OF MOLECULAR DIAGNOSTICS
- Insertion-and-deletion-derived tumour-specific neoantigens and the immunogenic phenotype: a pan-cancer analysis
- (2017) Samra Turajlic et al. LANCET ONCOLOGY
- Personalized RNA mutanome vaccines mobilize poly-specific therapeutic immunity against cancer
- (2017) Ugur Sahin et al. NATURE
- Quantifiable predictive features define epitope-specific T cell receptor repertoires
- (2017) Pradyot Dash et al. NATURE
- Identification of unique neoantigen qualities in long-term survivors of pancreatic cancer
- (2017) Vinod P. Balachandran et al. NATURE
- A neoantigen fitness model predicts tumour response to checkpoint blockade immunotherapy
- (2017) Marta Łuksza et al. NATURE
- An immunogenic personal neoantigen vaccine for patients with melanoma
- (2017) Patrick A. Ott et al. NATURE
- Generation of higher affinity T cell receptors by antigen-driven differentiation of progenitor T cells in vitro
- (2017) Thomas M Schmitt et al. NATURE BIOTECHNOLOGY
- The problem with neoantigen prediction
- (2017) NATURE BIOTECHNOLOGY
- Fast and accurate HLA typing from short-read next-generation sequence data with xHLA
- (2017) Chao Xie et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade
- (2017) Dung T. Le et al. SCIENCE
- Neoantigen Vaccines Pass the Immunogenicity Test
- (2017) Gerald P. Linette et al. TRENDS IN MOLECULAR MEDICINE
- Precision Oncology: The Road Ahead
- (2017) Daniela Senft et al. TRENDS IN MOLECULAR MEDICINE
- Pan-cancer Immunogenomic Analyses Reveal Genotype-Immunophenotype Relationships and Predictors of Response to Checkpoint Blockade
- (2017) Pornpimol Charoentong et al. Cell Reports
- Identification of Glycopeptides as Posttranslationally Modified Neoantigens in Leukemia
- (2017) Stacy A. Malaker et al. Cancer Immunology Research
- Identification and Characterization of Neoantigens As Well As Respective Immune Responses in Cancer Patients
- (2017) Eva Bräunlein et al. Frontiers in Immunology
- Neoantigens Generated by Individual Mutations and Their Role in Cancer Immunity and Immunotherapy
- (2017) Mirjana Efremova et al. Frontiers in Immunology
- Novel metrics to measure coverage in whole exome sequencing datasets reveal local and global non-uniformity
- (2017) Qingyu Wang et al. Scientific Reports
- Uptake of synthetic naked RNA by skin-resident dendritic cells via macropinocytosis allows antigen expression and induction of T-cell responses in mice
- (2016) Abderraouf Selmi et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Genomic and Transcriptomic Features of Response to Anti-PD-1 Therapy in Metastatic Melanoma
- (2016) Willy Hugo et al. CELL
- Integrative Analyses of Colorectal Cancer Show Immunoscore Is a Stronger Predictor of Patient Survival Than Microsatellite Instability
- (2016) Bernhard Mlecnik et al. IMMUNITY
- Vaccine adjuvants as potential cancer immunotherapeutics
- (2016) Burcu Temizoz et al. INTERNATIONAL IMMUNOLOGY
- Comparison of exome-based HLA class I genotyping tools: identification of platform-specific genotyping errors
- (2016) Kazuma Kiyotani et al. JOURNAL OF HUMAN GENETICS
- Immunotherapy: Cancer vaccine triggers antiviral-type defences
- (2016) Jolanda De Vries et al. NATURE
- Systemic RNA delivery to dendritic cells exploits antiviral defence for cancer immunotherapy
- (2016) Lena M. Kranz et al. NATURE
- Rekindling cancer vaccines
- (2016) Malorye Allison Branca NATURE BIOTECHNOLOGY
- Prospects for gene-engineered T cell immunotherapy for solid cancers
- (2016) Christopher A Klebanoff et al. NATURE MEDICINE
- T-Cell Transfer Therapy Targeting Mutant KRAS in Cancer
- (2016) Eric Tran et al. NEW ENGLAND JOURNAL OF MEDICINE
- Density of immunogenic antigens does not explain the presence or absence of the T-cell–inflamed tumor microenvironment in melanoma
- (2016) Stefani Spranger et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The "cancer immunogram"
- (2016) C. U. Blank et al. SCIENCE
- Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade
- (2016) N. McGranahan et al. SCIENCE
- Direct identification of clinically relevant neoepitopes presented on native human melanoma tissue by mass spectrometry
- (2016) Michal Bassani-Sternberg et al. Nature Communications
- Proteomics of Human Dendritic Cell Subsets Reveals Subset-Specific Surface Markers and Differential Inflammasome Function
- (2016) Kuntal Worah et al. Cell Reports
- Genomic Correlates of Immune-Cell Infiltrates in Colorectal Carcinoma
- (2016) Marios Giannakis et al. Cell Reports
- A Survey of Computational Tools to Analyze and Interpret Whole Exome Sequencing Data
- (2016) Jennifer D. Hintzsche et al. International Journal of Genomics
- Abstract 4864: VarDict: A novel and versatile variant caller for next-generation sequencing in cancer research
- (2015) Zhongwu Lai et al. CANCER RESEARCH
- New Strategies in Engineering T-cell Receptor Gene-Modified T cells to More Effectively Target Malignancies
- (2015) T. M. Schmitt et al. CLINICAL CANCER RESEARCH
- Immunogenic peptide discovery in cancer genomes
- (2015) Alexandra Snyder et al. CURRENT OPINION IN GENETICS & DEVELOPMENT
- TCR affinity for p/MHC formed by tumor antigens that are self-proteins: impact on efficacy and toxicity
- (2015) Jennifer D Stone et al. CURRENT OPINION IN IMMUNOLOGY
- Safety and Antitumor Activity of Anti–PD-1 Antibody, Nivolumab, in Patients With Platinum-Resistant Ovarian Cancer
- (2015) Junzo Hamanishi et al. JOURNAL OF CLINICAL ONCOLOGY
- Identification of human T-cell receptors with optimal affinity to cancer antigens using antigen-negative humanized mice
- (2015) Matthias Obenaus et al. NATURE BIOTECHNOLOGY
- Comprehensive analysis of cancer-associated somatic mutations in class I HLA genes
- (2015) Sachet A Shukla et al. NATURE BIOTECHNOLOGY
- Nivolumab versus Docetaxel in Advanced Squamous-Cell Non–Small-Cell Lung Cancer
- (2015) Julie Brahmer et al. NEW ENGLAND JOURNAL OF MEDICINE
- Nivolumab versus Everolimus in Advanced Renal-Cell Carcinoma
- (2015) Robert J. Motzer et al. NEW ENGLAND JOURNAL OF MEDICINE
- Genomic correlates of response to CTLA-4 blockade in metastatic melanoma
- (2015) E. M. Van Allen et al. SCIENCE
- Neoantigens in cancer immunotherapy
- (2015) T. N. Schumacher et al. SCIENCE
- A dendritic cell vaccine increases the breadth and diversity of melanoma neoantigen-specific T cells
- (2015) B. M. Carreno et al. SCIENCE
- Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer
- (2015) N. A. Rizvi et al. SCIENCE
- A comprehensive assessment of somatic mutation detection in cancer using whole-genome sequencing
- (2015) Tyler S. Alioto et al. Nature Communications
- Performance comparison of four commercial human whole-exome capture platforms
- (2015) Daichi Shigemizu et al. Scientific Reports
- Exome Sequencing: Current and Future Perspectives
- (2015) Amanda Warr et al. G3-Genes Genomes Genetics
- HLAreporter: a tool for HLA typing from next generation sequencing data
- (2015) Yazhi Huang et al. Genome Medicine
- Cross-presentation of cell-associated antigens by MHC class I in dendritic cell subsets
- (2015) Enric Gutiérrez-Martínez Frontiers in Immunology
- OptiType: precision HLA typing from next-generation sequencing data
- (2014) András Szolek et al. BIOINFORMATICS
- Inference of high resolution HLA types using genome-wide RNA or DNA sequencing reads
- (2014) Yu Bai et al. BMC GENOMICS
- Performance comparison of four exome capture systems for deep sequencing
- (2014) Chandra Sekhar Chilamakuri et al. BMC GENOMICS
- Dissecting the Tumor Myeloid Compartment Reveals Rare Activating Antigen-Presenting Cells Critical for T Cell Immunity
- (2014) Miranda L. Broz et al. CANCER CELL
- Dendritic cell maturation: functional specialization through signaling specificity and transcriptional programming
- (2014) M. Dalod et al. EMBO JOURNAL
- Predicting immunogenic tumour mutations by combining mass spectrometry and exome sequencing
- (2014) Mahesh Yadav et al. NATURE
- MPDL3280A (anti-PD-L1) treatment leads to clinical activity in metastatic bladder cancer
- (2014) Thomas Powles et al. NATURE
- PD-1 blockade induces responses by inhibiting adaptive immune resistance
- (2014) Paul C. Tumeh et al. NATURE
- Cancer Immunotherapy Based on Mutation-Specific CD4+ T Cells in a Patient with Epithelial Cancer
- (2014) E. Tran et al. SCIENCE
- Detailed comparison of two popular variant calling packages for exome and targeted exon studies
- (2014) Charles D. Warden et al. PeerJ
- Human Dendritic Cell Functional Specialization in Steady-State and Inflammation
- (2014) Arjan Boltjes et al. Frontiers in Immunology
- The Dendritic Cell Lineage: Ontogeny and Function of Dendritic Cells and Their Subsets in the Steady State and the Inflamed Setting
- (2013) Miriam Merad et al. Annual Review of Immunology
- Pathways of Antigen Processing
- (2013) Janice S. Blum et al. Annual Review of Immunology
- Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples
- (2013) Kristian Cibulskis et al. NATURE BIOTECHNOLOGY
- Mining exomic sequencing data to identify mutated antigens recognized by adoptively transferred tumor-reactive T cells
- (2013) Paul F Robbins et al. NATURE MEDICINE
- HLA Haplotyping from RNA-seq Data Using Hierarchical Read Weighting
- (2013) Hyunsung John Kim et al. PLoS One
- Sequencing quality assessment tools to enable data-driven informatics for high throughput genomics
- (2013) Richard M. Leggett et al. Frontiers in Genetics
- STAR: ultrafast universal RNA-seq aligner
- (2012) Alexander Dobin et al. BIOINFORMATICS
- Experimental models to investigate the function of dendritic cell subsets: challenges and implications
- (2012) D. G. Hancock et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
- Safety, Activity, and Immune Correlates of Anti–PD-1 Antibody in Cancer
- (2012) Suzanne L. Topalian et al. NEW ENGLAND JOURNAL OF MEDICINE
- A fast and accurate SNP detection algorithm for next-generation sequencing data
- (2012) Feng Xu et al. Nature Communications
- HLA typing from RNA-Seq sequence reads
- (2012) Sebastian Boegel et al. Genome Medicine
- Derivation of HLA types from shotgun sequence datasets
- (2012) René L Warren et al. Genome Medicine
- SomaticSniper: identification of somatic point mutations in whole genome sequencing data
- (2011) David E. Larson et al. BIOINFORMATICS
- Engineering Dendritic Cells to Enhance Cancer Immunotherapy
- (2011) Jeanette E Boudreau et al. MOLECULAR THERAPY
- Performance comparison of exome DNA sequencing technologies
- (2011) Michael J Clark et al. NATURE BIOTECHNOLOGY
- A framework for variation discovery and genotyping using next-generation DNA sequencing data
- (2011) Mark A DePristo et al. NATURE GENETICS
- Fast and accurate long-read alignment with Burrows–Wheeler transform
- (2010) Heng Li et al. BIOINFORMATICS
- MHC Class II epitope predictive algorithms
- (2010) Morten Nielsen et al. IMMUNOLOGY
- Human CD141+(BDCA-3)+dendritic cells (DCs) represent a unique myeloid DC subset that cross-presents necrotic cell antigens
- (2010) Sarah L. Jongbloed et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Improved Survival with Ipilimumab in Patients with Metastatic Melanoma
- (2010) F. Stephen Hodi et al. NEW ENGLAND JOURNAL OF MEDICINE
- Increasing functional avidity of TCR-redirected T cells by removing definedN-glycosylation sites in the TCR constant domain
- (2009) Jürgen Kuball et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Immune Response Against Frameshift-Induced Neopeptides in HNPCC Patients and Healthy HNPCC Mutation Carriers
- (2008) Yvette Schwitalle et al. GASTROENTEROLOGY
- Class II major histocompatibility complex tetramer staining: progress, problems, and prospects
- (2008) Sabrina S. Vollers et al. IMMUNOLOGY
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