Immunopeptidomics of colorectal cancer organoids reveals a sparse HLA class I neoantigen landscape and no increase in neoantigens with interferon or MEK-inhibitor treatment
出版年份 2019 全文链接
标题
Immunopeptidomics of colorectal cancer organoids reveals a sparse HLA class I neoantigen landscape and no increase in neoantigens with interferon or MEK-inhibitor treatment
作者
关键词
-
出版物
Journal for ImmunoTherapy of Cancer
Volume 7, Issue 1, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2019-11-18
DOI
10.1186/s40425-019-0769-8
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Multi-omics discovery of exome-derived neoantigens in hepatocellular carcinoma
- (2019) Markus W. Löffler et al. Genome Medicine
- CEA expression heterogeneity and plasticity confer resistance to the CEA-targeting bispecific immunotherapy antibody cibisatamab (CEA-TCB) in patient-derived colorectal cancer organoids
- (2019) Reyes Gonzalez-Exposito et al. Journal for ImmunoTherapy of Cancer
- Genomic and Transcriptomic Determinants of Therapy Resistance and Immune Landscape Evolution during Anti-EGFR Treatment in Colorectal Cancer
- (2019) Andrew Woolston et al. CANCER CELL
- Atezolizumab with or without cobimetinib versus regorafenib in previously treated metastatic colorectal cancer (IMblaze370): a multicentre, open-label, phase 3, randomised, controlled trial
- (2019) Cathy Eng et al. LANCET ONCOLOGY
- Robust prediction of HLA class II epitopes by deep motif deconvolution of immunopeptidomes
- (2019) Julien Racle et al. NATURE BIOTECHNOLOGY
- Mapping the HLA ligandome of Colorectal Cancer Reveals an Imprint of Malignant Cell Transformation
- (2018) Markus W. Löffler et al. CANCER RESEARCH
- Personalized vaccines for cancer immunotherapy
- (2018) Ugur Sahin et al. SCIENCE
- Genetic Mechanisms of Immune Evasion in Colorectal Cancer
- (2018) Catherine S. Grasso et al. Cancer Discovery
- Identification of non-mutated neoantigens presented by TAP-deficient tumors
- (2018) Koen A. Marijt et al. JOURNAL OF EXPERIMENTAL MEDICINE
- The PRIDE database and related tools and resources in 2019: improving support for quantification data
- (2018) Yasset Perez-Riverol et al. NUCLEIC ACIDS RESEARCH
- Mass Spectrometry Profiling of HLA-Associated Peptidomes in Mono-allelic Cells Enables More Accurate Epitope Prediction
- (2017) Jennifer G. Abelin et al. IMMUNITY
- High-throughput and Sensitive Immunopeptidomics Platform Reveals Profound Interferonγ-Mediated Remodeling of the Human Leukocyte Antigen (HLA) Ligandome
- (2017) Chloe Chong et al. MOLECULAR & CELLULAR PROTEOMICS
- Personalized RNA mutanome vaccines mobilize poly-specific therapeutic immunity against cancer
- (2017) Ugur Sahin et al. NATURE
- An immunogenic personal neoantigen vaccine for patients with melanoma
- (2017) Patrick A. Ott et al. NATURE
- The immunopeptidomic landscape of ovarian carcinomas
- (2017) Heiko Schuster et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Patient HLA class I genotype influences cancer response to checkpoint blockade immunotherapy
- (2017) Diego Chowell et al. SCIENCE
- Mutational signatures reveal the dynamic interplay of risk factors and cellular processes during liver tumorigenesis
- (2017) Eric Letouzé et al. Nature Communications
- Pan-cancer Immunogenomic Analyses Reveal Genotype-Immunophenotype Relationships and Predictors of Response to Checkpoint Blockade
- (2017) Pornpimol Charoentong et al. Cell Reports
- ‘Hotspots’ of Antigen Presentation Revealed by Human Leukocyte Antigen Ligandomics for Neoantigen Prioritization
- (2017) Markus Müller et al. Frontiers in Immunology
- Loss of IFN-γ Pathway Genes in Tumor Cells as a Mechanism of Resistance to Anti-CTLA-4 Therapy
- (2016) Jianjun Gao et al. CELL
- Mass spectrometry-based antigen discovery for cancer immunotherapy
- (2016) Michal Bassani-Sternberg et al. CURRENT OPINION IN IMMUNOLOGY
- MAP Kinase Inhibition Promotes T Cell and Anti-tumor Activity in Combination with PD-L1 Checkpoint Blockade
- (2016) Peter J.R. Ebert et al. IMMUNITY
- Unsupervised HLA Peptidome Deconvolution Improves Ligand Prediction Accuracy and Predicts Cooperative Effects in Peptide–HLA Interactions
- (2016) Michal Bassani-Sternberg et al. JOURNAL OF IMMUNOLOGY
- The Perseus computational platform for comprehensive analysis of (prote)omics data
- (2016) Stefka Tyanova et al. NATURE METHODS
- Global proteogenomic analysis of human MHC class I-associated peptides derived from non-canonical reading frames
- (2016) Céline M. Laumont et al. Nature Communications
- Direct identification of clinically relevant neoepitopes presented on native human melanoma tissue by mass spectrometry
- (2016) Michal Bassani-Sternberg et al. Nature Communications
- Prospective Derivation of a Living Organoid Biobank of Colorectal Cancer Patients
- (2015) Marc van de Wetering et al. CELL
- The BRAF and MEK Inhibitors Dabrafenib and Trametinib: Effects on Immune Function and in Combination with Immunomodulatory Antibodies Targeting PD-1, PD-L1, and CTLA-4
- (2015) L. Liu et al. CLINICAL CANCER RESEARCH
- Comprehensive analysis of cancer-associated somatic mutations in class I HLA genes
- (2015) Sachet A Shukla et al. NATURE BIOTECHNOLOGY
- PD-1 Blockade in Tumors with Mismatch-Repair Deficiency
- (2015) Dung T. Le et al. NEW ENGLAND JOURNAL OF MEDICINE
- Immunogenicity of somatic mutations in human gastrointestinal cancers
- (2015) E. Tran et al. SCIENCE
- HLA Class II Antigen Expression in Colorectal Carcinoma Tumors as a Favorable Prognostic Marker
- (2015) Giuseppe Sconocchia et al. NEOPLASIA
- Clinical Effects of Adjuvant Active Specific Immunotherapy Differ between Patients with Microsatellite-Stable and Microsatellite-Instable Colon Cancer
- (2011) V. A. de Weger et al. CLINICAL CANCER RESEARCH
- Long-term Expansion of Epithelial Organoids From Human Colon, Adenoma, Adenocarcinoma, and Barrett's Epithelium
- (2011) Toshiro Sato et al. GASTROENTEROLOGY
- Identification of FAM46D as a novel cancer/testis antigen using EST data and serological analysis
- (2009) Fabiana Bettoni et al. GENOMICS
- Systematic Characterisation of Cellular Localisation and Expression Profiles of Proteins Containing MHC Ligands
- (2009) Agnieszka S. Juncker et al. PLoS One
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started