标题
ALS Genetics, Mechanisms, and Therapeutics: Where Are We Now?
作者
关键词
-
出版物
Frontiers in Neuroscience
Volume 13, Issue -, Pages -
出版商
Frontiers Media SA
发表日期
2019-12-06
DOI
10.3389/fnins.2019.01310
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- ALS-implicated protein TDP-43 sustains levels of STMN2, a mediator of motor neuron growth and repair
- (2019) Joseph R. Klim et al. NATURE NEUROSCIENCE
- Caspase-4 mediates cytoplasmic accumulation of TDP-43 in the primate brains
- (2019) Peng Yin et al. ACTA NEUROPATHOLOGICA
- Misfolded SOD1 inclusions in patients with mutations in C9orf72 and other ALS/FTD-associated genes
- (2019) Karin Forsberg et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- Multi-platform discovery of haplotype-resolved structural variation in human genomes
- (2019) Mark J. P. Chaisson et al. Nature Communications
- Comprehensive evaluation and characterisation of short read general-purpose structural variant calling software
- (2019) Daniel L. Cameron et al. Nature Communications
- Genetic polymorphisms in amyotrophic lateral sclerosis: Evidence for implication in detoxification pathways of environmental toxicants
- (2018) Efthimios Dardiotis et al. ENVIRONMENT INTERNATIONAL
- New FIG4 gene mutations causing aggressive ALS
- (2018) C. Bertolin et al. EUROPEAN JOURNAL OF NEUROLOGY
- TDP-43 post-translational modifications in health and disease
- (2018) Emanuele Buratti EXPERT OPINION ON THERAPEUTIC TARGETS
- Oligogenic genetic variation of neurodegenerative disease genes in 980 postmortem human brains
- (2018) Michael J Keogh et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- NEK1 genetic variability in a Belgian cohort of ALS and ALS-FTD patients
- (2018) Hung Phuoc Nguyen et al. NEUROBIOLOGY OF AGING
- Molecular epidemiological study of familial amyotrophic lateral sclerosis in Japanese population by whole-exome sequencing and identification of novel HNRNPA1 mutation
- (2018) Hiroya Naruse et al. NEUROBIOLOGY OF AGING
- ATXN1 intermediate-length polyglutamine expansions are associated with amyotrophic lateral sclerosis
- (2018) Serena Lattante et al. NEUROBIOLOGY OF AGING
- Mutation screening of NEK1 in Chinese ALS patients
- (2018) Shi Shu et al. NEUROBIOLOGY OF AGING
- Identification of compound heterozygous variants in OPTN in an ALS-FTD patient from the CReATe consortium: a case report
- (2018) Cyril Pottier et al. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration
- Modeling Protein Aggregation and the Heat Shock Response in ALS iPSC-Derived Motor Neurons
- (2018) Emily R. Seminary et al. Frontiers in Neuroscience
- Inotersen: First Global Approval
- (2018) Susan J. Keam DRUGS
- FIG4 variants in central European patients with amyotrophic lateral sclerosis: a whole-exome and targeted sequencing study
- (2017) Alma Osmanovic et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- Clinical efficacy of edaravone for the treatment of amyotrophic lateral sclerosis
- (2017) Hideyuki Sawada EXPERT OPINION ON PHARMACOTHERAPY
- How the discovery of ISS-N1 led to the first medical therapy for spinal muscular atrophy
- (2017) N N Singh et al. GENE THERAPY
- Defects in optineurin- and myosin VI-mediated cellular trafficking in amyotrophic lateral sclerosis
- (2017) Vinod Sundaramoorthy et al. HUMAN MOLECULAR GENETICS
- Oligodendroglia: metabolic supporters of neurons
- (2017) Thomas Philips et al. JOURNAL OF CLINICAL INVESTIGATION
- Microglia and C9orf72 in neuroinflammation and ALS and frontotemporal dementia
- (2017) Deepti Lall et al. JOURNAL OF CLINICAL INVESTIGATION
- Neuron-to-Neuron Transfer of FUS in Drosophila Primary Neuronal Culture Is Enhanced by ALS-Associated Mutations
- (2017) Sébastien Feuillette et al. JOURNAL OF MOLECULAR NEUROSCIENCE
- Fasciculation in amyotrophic lateral sclerosis: origin and pathophysiological relevance
- (2017) Mamede de Carvalho et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- Genetic epidemiology of amyotrophic lateral sclerosis: a systematic review and meta-analysis
- (2017) Zhang-Yu Zou et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- Therapeutic reduction of ataxin-2 extends lifespan and reduces pathology in TDP-43 mice
- (2017) Lindsay A. Becker et al. NATURE
- Neurotoxic reactive astrocytes are induced by activated microglia
- (2017) Shane A. Liddelow et al. NATURE
- The chemical evolution of oligonucleotide therapies of clinical utility
- (2017) Anastasia Khvorova et al. NATURE BIOTECHNOLOGY
- The impact of structural variation on human gene expression
- (2017) Colby Chiang et al. NATURE GENETICS
- Burden of rare variants in ALS genes influences survival in familial and sporadic ALS
- (2017) Shirley Yin-Yu Pang et al. NEUROBIOLOGY OF AGING
- ATXN2 trinucleotide repeat length correlates with risk of ALS
- (2017) William Sproviero et al. NEUROBIOLOGY OF AGING
- Genetic and Pathological Assessment of hnRNPA1, hnRNPA2/B1, and hnRNPA3 in Familial and Sporadic Amyotrophic Lateral Sclerosis
- (2017) Jennifer A. Fifita et al. Neurodegenerative Diseases
- Meta-analysis of pharmacogenetic interactions in amyotrophic lateral sclerosis clinical trials
- (2017) Ruben P.A. van Eijk et al. NEUROLOGY
- Lost in Transportation: Nucleocytoplasmic Transport Defects in ALS and Other Neurodegenerative Diseases
- (2017) Hong Joo Kim et al. NEURON
- RNA Misprocessing in C9orf72-Linked Neurodegeneration
- (2017) Holly V. Barker et al. Frontiers in Cellular Neuroscience
- HDAC6 inhibition reverses axonal transport defects in motor neurons derived from FUS-ALS patients
- (2017) Wenting Guo et al. Nature Communications
- Age-related penetrance of the C9orf72 repeat expansion
- (2017) Natalie A. Murphy et al. Scientific Reports
- ALS Clinical Trials Review: 20 Years of Failure. Are We Any Closer to Registering a New Treatment?
- (2017) Dmitry Petrov et al. Frontiers in Aging Neuroscience
- Advances in the delivery of RNA therapeutics: from concept to clinical reality
- (2017) James C. Kaczmarek et al. Genome Medicine
- TBK1: a new player in ALS linking autophagy and neuroinflammation
- (2017) James A. Oakes et al. Molecular Brain
- Young-onset rapidly progressive ALS associated with heterozygous FUS mutation
- (2017) Marta Gromicho et al. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration
- Direct Reprogramming Rather than iPSC-Based Reprogramming Maintains Aging Hallmarks in Human Motor Neurons
- (2017) Yu Tang et al. Frontiers in Molecular Neuroscience
- The Enigmatic Role of C9ORF72 in Autophagy
- (2017) Melissa Nassif et al. Frontiers in Neuroscience
- Genetic Correction of SOD1 Mutant iPSCs Reveals ERK and JNK Activated AP1 as a Driver of Neurodegeneration in Amyotrophic Lateral Sclerosis
- (2017) Akshay Bhinge et al. Stem Cell Reports
- Role of Neuroinflammation in Amyotrophic Lateral Sclerosis: Cellular Mechanisms and Therapeutic Implications
- (2017) Jia Liu et al. Frontiers in Immunology
- NEK1mutations in familial amyotrophic lateral sclerosis
- (2016) David Brenner et al. BRAIN
- Mechanisms of FUS mutations in familial amyotrophic lateral sclerosis
- (2016) Yulei Shang et al. BRAIN RESEARCH
- Toxic gain of function from mutant FUS protein is crucial to trigger cell autonomous motor neuron loss
- (2016) Jelena Scekic‐Zahirovic et al. EMBO JOURNAL
- Optineurin: The autophagy connection
- (2016) Hongyu Ying et al. EXPERIMENTAL EYE RESEARCH
- Excitotoxicity in ALS: Overstimulation, or overreaction?
- (2016) Anna E. King et al. EXPERIMENTAL NEUROLOGY
- Structural variants can be more informative for disease diagnostics, prognostics and translation than current SNP mapping and exon sequencing
- (2016) Allen D. Roses et al. Expert Opinion on Drug Metabolism & Toxicology
- TDP-43 binds and transports G-quadruplex-containing mRNAs into neurites for local translation
- (2016) Akira Ishiguro et al. GENES TO CELLS
- Physiological functions and pathobiology of TDP-43 and FUS/TLS proteins
- (2016) Antonia Ratti et al. JOURNAL OF NEUROCHEMISTRY
- Insights into the pathogenic mechanisms of Chromosome 9 open reading frame 72 (C9orf72) repeat expansions
- (2016) Tiffany W. Todd et al. JOURNAL OF NEUROCHEMISTRY
- Directly converted patient-specific induced neurons mirror the neuropathology of FUS with disrupted nuclear localization in amyotrophic lateral sclerosis
- (2016) Su Min Lim et al. Molecular Neurodegeneration
- Eteplirsen Approved for Duchenne Muscular Dystrophy: The FDA Faces a Difficult Choice
- (2016) Cy A Stein MOLECULAR THERAPY
- NEK1 variants confer susceptibility to amyotrophic lateral sclerosis
- (2016) Kevin P Kenna et al. NATURE GENETICS
- Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis
- (2016) Wouter van Rheenen et al. NATURE GENETICS
- Modeling ALS with motor neurons derived from human induced pluripotent stem cells
- (2016) Samuel Sances et al. NATURE NEUROSCIENCE
- TBK1 is associated with ALS and ALS-FTD in Sardinian patients
- (2016) Giuseppe Borghero et al. NEUROBIOLOGY OF AGING
- Gain of Toxicity from ALS/FTD-Linked Repeat Expansions in C9ORF72 Is Alleviated by Antisense Oligonucleotides Targeting GGGGCC-Containing RNAs
- (2016) Jie Jiang et al. NEURON
- Prevalence of brain and spinal cord inclusions, including dipeptide repeat proteins, in patients with the C9ORF72 hexanucleotide repeat expansion: a systematic neuropathological review
- (2016) L. J. Schipper et al. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY
- Increased cytoplasmicTARDBPmRNA in affected spinal motor neurons in ALS caused by abnormal autoregulation of TDP-43
- (2016) Akihide Koyama et al. NUCLEIC ACIDS RESEARCH
- Two familial ALS proteins function in prevention/repair of transcription-associated DNA damage
- (2016) Sarah J. Hill et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Loss-of-function mutations in the C9ORF72 mouse ortholog cause fatal autoimmune disease
- (2016) Aaron Burberry et al. Science Translational Medicine
- Principles and Properties of Stress Granules
- (2016) David S.W. Protter et al. TRENDS IN CELL BIOLOGY
- ALS-associated mutant FUS induces selective motor neuron degeneration through toxic gain of function
- (2016) Aarti Sharma et al. Nature Communications
- Direct Lineage Reprogramming Reveals Disease-Specific Phenotypes of Motor Neurons from Human ALS Patients
- (2016) Meng-Lu Liu et al. Cell Reports
- Genetic analysis of patients with familial and sporadic amyotrophic lateral sclerosis in a Brazilian Research Center
- (2016) Gerson Chadi et al. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration
- An Amyloid-Like Pathological Conformation of TDP-43 Is Stabilized by Hypercooperative Hydrogen Bonds
- (2016) Miguel Mompeán et al. Frontiers in Molecular Neuroscience
- Establishment of In Vitro FUS-Associated Familial Amyotrophic Lateral Sclerosis Model Using Human Induced Pluripotent Stem Cells
- (2016) Naoki Ichiyanagi et al. Stem Cell Reports
- Genotype-phenotype correlations of amyotrophic lateral sclerosis
- (2016) Hong-Fu Li et al. Translational Neurodegeneration
- Heterogeneity of cerebral TDP-43 pathology in sporadic amyotrophic lateral sclerosis: Evidence for clinico-pathologic subtypes
- (2016) Ryoko Takeuchi et al. Acta Neuropathologica Communications
- ALS-linked misfolded SOD1 species have divergent impacts on mitochondria
- (2016) Sarah Pickles et al. Acta Neuropathologica Communications
- Pathogenesis of FUS-associated ALS and FTD: insights from rodent models
- (2016) Matthew Nolan et al. Acta Neuropathologica Communications
- C9orf72 ablation causes immune dysregulation characterized by leukocyte expansion, autoantibody production and glomerulonephropathy in mice
- (2016) Amanda Atanasio et al. Scientific Reports
- Antisense oligonucleotides in therapy for neurodegenerative disorders
- (2015) Melvin M. Evers et al. ADVANCED DRUG DELIVERY REVIEWS
- Isoform-specific antibodies reveal distinct subcellular localizations of C9orf72 in amyotrophic lateral sclerosis
- (2015) Shangxi Xiao et al. ANNALS OF NEUROLOGY
- C9orf72 ablation in mice does not cause motor neuron degeneration or motor deficits
- (2015) Max Koppers et al. ANNALS OF NEUROLOGY
- From transcriptomic to protein level changes in TDP-43 and FUS loss-of-function cell models
- (2015) Claudia Colombrita et al. Biochimica et Biophysica Acta-Gene Regulatory Mechanisms
- V42. De novo mutations in the FUS gene are a frequent cause of sporadic ALS in very young patients
- (2015) A. Hübers et al. CLINICAL NEUROPHYSIOLOGY
- ALS mutant FUS proteins are recruited into stress granules in induced pluripotent stem cell-derived motoneurons
- (2015) J. Lenzi et al. Disease Models & Mechanisms
- Prion-like domains in RNA binding proteins are essential for building subnuclear paraspeckles
- (2015) Sven Hennig et al. JOURNAL OF CELL BIOLOGY
- UNC13A confers risk for sporadic ALS and influences survival in a Spanish cohort
- (2015) Jose Manuel Vidal-Taboada et al. JOURNAL OF NEUROLOGY
- TUBA4A gene analysis in sporadic amyotrophic lateral sclerosis: identification of novel mutations
- (2015) Viviana Pensato et al. JOURNAL OF NEUROLOGY
- Autophagy receptor defects and ALS-FTLD
- (2015) Veronika Majcher et al. MOLECULAR AND CELLULAR NEUROSCIENCE
- Cytoplasmic mislocalization of RNA splicing factors and aberrant neuronal gene splicing in TDP-43 transgenic pig brain
- (2015) Guohao Wang et al. Molecular Neurodegeneration
- GGGGCC repeat expansion in C9orf72 compromises nucleocytoplasmic transport
- (2015) Brian D. Freibaum et al. NATURE
- Haploinsufficiency of TBK1 causes familial ALS and fronto-temporal dementia
- (2015) Axel Freischmidt et al. NATURE NEUROSCIENCE
- Novel mutations support a role for Profilin 1 in the pathogenesis of ALS
- (2015) Bradley N. Smith et al. NEUROBIOLOGY OF AGING
- De novo FUS mutations are the most frequent genetic cause in early-onset German ALS patients
- (2015) Annemarie Hübers et al. NEUROBIOLOGY OF AGING
- Stepwise acquirement of hallmark neuropathology in FUS-ALS iPSC models depends on mutation type and neuronal aging
- (2015) Julia Japtok et al. NEUROBIOLOGY OF DISEASE
- Molecular classification of amyotrophic lateral sclerosis by unsupervised clustering of gene expression in motor cortex
- (2015) Eleonora Aronica et al. NEUROBIOLOGY OF DISEASE
- Epidemiology of Amyotrophic Lateral Sclerosis and Effect of Riluzole on Disease Course
- (2015) Hakan Cetin et al. NEUROEPIDEMIOLOGY
- In silico analysis of SIGMAR1 variant (rs4879809) segregating in a consanguineous Pakistani family showing amyotrophic lateral sclerosis without frontotemporal lobar dementia
- (2015) Muhammad Ikram Ullah et al. NEUROGENETICS
- Familial Amyotrophic Lateral Sclerosis
- (2015) Kevin Boylan NEUROLOGIC CLINICS
- Human C9ORF72 Hexanucleotide Expansion Reproduces RNA Foci and Dipeptide Repeat Proteins but Not Neurodegeneration in BAC Transgenic Mice
- (2015) Owen M. Peters et al. NEURON
- C9orf72 BAC Transgenic Mice Display Typical Pathologic Features of ALS/FTD
- (2015) Jacqueline G. O’Rourke et al. NEURON
- Studies of alternative isoforms provide insight into TDP-43 autoregulation and pathogenesis
- (2015) S. D'Alton et al. RNA
- C9ORF72 repeat expansions in mice cause TDP-43 pathology, neuronal loss, and behavioral deficits
- (2015) J. Chew et al. SCIENCE
- Exome sequencing in amyotrophic lateral sclerosis identifies risk genes and pathways
- (2015) E. T. Cirulli et al. SCIENCE
- An acetylation switch controls TDP-43 function and aggregation propensity
- (2015) Todd J. Cohen et al. Nature Communications
- A Systematic Analysis of Factors Localized to Damaged Chromatin Reveals PARP-Dependent Recruitment of Transcription Factors
- (2015) Lior Izhar et al. Cell Reports
- FUS Interacts with HSP60 to Promote Mitochondrial Damage
- (2015) Jianwen Deng et al. PLoS Genetics
- Early lethality and neuronal proteinopathy in mice expressing cytoplasm-targeted FUS that lacks the RNA recognition motif
- (2015) Hannah K. Robinson et al. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration
- Golgi fragmentation in amyotrophic lateral sclerosis, an overview of possible triggers and consequences
- (2015) Vinod Sundaramoorthy et al. Frontiers in Neuroscience
- Genotype-phenotype relationship in hereditary amyotrophic lateral sclerosis
- (2015) Satoshi Yamashita et al. Translational Neurodegeneration
- FUS/TLS deficiency causes behavioral and pathological abnormalities distinct from amyotrophic lateral sclerosis
- (2015) Yoshihiro Kino et al. Acta Neuropathologica Communications
- Prion-like Mechanism in Amyotrophic Lateral Sclerosis: are Protein Aggregates the Key?
- (2015) Shynrye Lee et al. Experimental Neurobiology
- Amyotrophic lateral sclerosis onset is influenced by the burden of rare variants in known amyotrophic lateral sclerosis genes
- (2014) Janet Cady et al. ANNALS OF NEUROLOGY
- Mutations in the CHCHD10 gene are a common cause of familial amyotrophic lateral sclerosis
- (2014) Janel O. Johnson et al. BRAIN
- Sequestration of multiple RNA recognition motif-containing proteins by C9orf72 repeat expansions
- (2014) Johnathan Cooper-Knock et al. BRAIN
- A mitochondrial origin for frontotemporal dementia and amyotrophic lateral sclerosis through CHCHD10 involvement
- (2014) Sylvie Bannwarth et al. BRAIN
- Species-dependent neuropathology in transgenic SOD1 pigs
- (2014) Huaqiang Yang et al. CELL RESEARCH
- C9ORF72, implicated in amytrophic lateral sclerosis and frontotemporal dementia, regulates endosomal trafficking
- (2014) Manal A. Farg et al. HUMAN MOLECULAR GENETICS
- ALS-associated mutation FUS-R521C causes DNA damage and RNA splicing defects
- (2014) Haiyan Qiu et al. JOURNAL OF CLINICAL INVESTIGATION
- Safety and efficacy of ceftriaxone for amyotrophic lateral sclerosis: a multi-stage, randomised, double-blind, placebo-controlled trial
- (2014) Merit E Cudkowicz et al. LANCET NEUROLOGY
- Resolving the complexity of the human genome using single-molecule sequencing
- (2014) Mark J. P. Chaisson et al. NATURE
- Mutations in the Matrin 3 gene cause familial amyotrophic lateral sclerosis
- (2014) Janel O Johnson et al. NATURE NEUROSCIENCE
- Screening of CHCHD10 in a French cohort confirms the involvement of this gene in frontotemporal dementia with amyotrophic lateral sclerosis patients
- (2014) Annabelle Chaussenot et al. NEUROBIOLOGY OF AGING
- Reduced C9orf72 protein levels in frontal cortex of amyotrophic lateral sclerosis and frontotemporal degeneration brain with the C9ORF72 hexanucleotide repeat expansion
- (2014) Adrian J. Waite et al. NEUROBIOLOGY OF AGING
- Identify mutation in amyotrophic lateral sclerosis cases using HaloPlex target enrichment system
- (2014) Zhi-Jun Liu et al. NEUROBIOLOGY OF AGING
- Discovery of a Biomarker and Lead Small Molecules to Target r(GGGGCC)-Associated Defects in c9FTD/ALS
- (2014) Zhaoming Su et al. NEURON
- Axonal Transport of TDP-43 mRNA Granules Is Impaired by ALS-Causing Mutations
- (2014) Nael H. Alami et al. NEURON
- Exome-wide Rare Variant Analysis Identifies TUBA4A Mutations Associated with Familial ALS
- (2014) Bradley N. Smith et al. NEURON
- Loss of nuclear TDP-43 in amyotrophic lateral sclerosis (ALS) causes altered expression of splicing machinery and widespread dysregulation of RNA splicing in motor neurones
- (2014) J. Robin Highley et al. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY
- Allele-Specific Knockdown of ALS-Associated Mutant TDP-43 in Neural Stem Cells Derived from Induced Pluripotent Stem Cells
- (2014) Agnes L. Nishimura et al. PLoS One
- Confirmatory double-blind, parallel-group, placebo-controlled study of efficacy and safety of edaravone (MCI-186) in amyotrophic lateral sclerosis patients
- (2014) Koji Abe et al. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration
- Golgi fragmentation precedes neuromuscular denervation and is associated with endosome abnormalities in SOD1-ALS mouse motor neurons
- (2014) Vera van Dis et al. Acta Neuropathologica Communications
- Antisense transcripts of the expanded C9ORF72 hexanucleotide repeat form nuclear RNA foci and undergo repeat-associated non-ATG translation in c9FTD/ALS
- (2013) Tania F. Gendron et al. ACTA NEUROPATHOLOGICA
- Frontotemporal dementia–amyotrophic lateral sclerosis syndrome locus on chromosome 16p12.1–q12.2: genetic, clinical and neuropathological analysis
- (2013) Carol Dobson-Stone et al. ACTA NEUROPATHOLOGICA
- hnRNP A3 binds to GGGGCC repeats and is a constituent of p62-positive/TDP43-negative inclusions in the hippocampus of patients with C9orf72 mutations
- (2013) Kohji Mori et al. ACTA NEUROPATHOLOGICA
- Modeling key pathological features of frontotemporal dementia with C9ORF72 repeat expansion in iPSC-derived human neurons
- (2013) Sandra Almeida et al. ACTA NEUROPATHOLOGICA
- ERBB4 Mutations that Disrupt the Neuregulin-ErbB4 Pathway Cause Amyotrophic Lateral Sclerosis Type 19
- (2013) Yuji Takahashi et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Stages of pTDP-43 pathology in amyotrophic lateral sclerosis
- (2013) Johannes Brettschneider et al. ANNALS OF NEUROLOGY
- Genetic and Epigenetic Variations in iPSCs: Potential Causes and Implications for Application
- (2013) Gaoyang Liang et al. Cell Stem Cell
- A genome-wide association meta-analysis identifies a novel locus at 17q11.2 associated with sporadic amyotrophic lateral sclerosis
- (2013) I. Fogh et al. HUMAN MOLECULAR GENETICS
- A patient-derived olfactory stem cell disease model for ataxia-telangiectasia
- (2013) Romal Stewart et al. HUMAN MOLECULAR GENETICS
- ALS mutant FUS disrupts nuclear localization and sequesters wild-type FUS within cytoplasmic stress granules
- (2013) Caroline Vance et al. HUMAN MOLECULAR GENETICS
- The ALS disease-associated mutant TDP-43 impairs mitochondrial dynamics and function in motor neurons
- (2013) Wenzhang Wang et al. HUMAN MOLECULAR GENETICS
- TARDBPandFUSMutations Associated with Amyotrophic Lateral Sclerosis: Summary and Update
- (2013) Serena Lattante et al. HUMAN MUTATION
- The RNA-binding Protein Fused in Sarcoma (FUS) Functions Downstream of Poly(ADP-ribose) Polymerase (PARP) in Response to DNA Damage
- (2013) Adam S. Mastrocola et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Intranuclear Aggregation of Mutant FUS/TLS as a Molecular Pathomechanism of Amyotrophic Lateral Sclerosis
- (2013) Takao Nomura et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Fused in Sarcoma (FUS) Protein Lacking Nuclear Localization Signal (NLS) and Major RNA Binding Motifs Triggers Proteinopathy and Severe Motor Phenotype in Transgenic Mice
- (2013) Tatyana A. Shelkovnikova et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Delineating the genetic heterogeneity of ALS using targeted high-throughput sequencing
- (2013) Kevin P Kenna et al. JOURNAL OF MEDICAL GENETICS
- Foot-and-Mouth Disease Virus 3C Protease Induces Fragmentation of the Golgi Compartment and Blocks Intra-Golgi Transport
- (2013) Z. Zhou et al. JOURNAL OF VIROLOGY
- An antisense oligonucleotide against SOD1 delivered intrathecally for patients with SOD1 familial amyotrophic lateral sclerosis: a phase 1, randomised, first-in-man study
- (2013) Timothy M Miller et al. LANCET NEUROLOGY
- The wobbler mouse, an ALS animal model
- (2013) Jakob Maximilian Moser et al. MOLECULAR GENETICS AND GENOMICS
- Genetics of amyotrophic lateral sclerosis: an update
- (2013) Sheng Chen et al. Molecular Neurodegeneration
- Mutations in prion-like domains in hnRNPA2B1 and hnRNPA1 cause multisystem proteinopathy and ALS
- (2013) Hong Joo Kim et al. NATURE
- Degeneration and impaired regeneration of gray matter oligodendrocytes in amyotrophic lateral sclerosis
- (2013) Shin H Kang et al. NATURE NEUROSCIENCE
- Interaction of FUS and HDAC1 regulates DNA damage response and repair in neurons
- (2013) Wen-Yuan Wang et al. NATURE NEUROSCIENCE
- State of play in amyotrophic lateral sclerosis genetics
- (2013) Alan E Renton et al. NATURE NEUROSCIENCE
- Emerging roles of astrocytes in neural circuit development
- (2013) Laura E. Clarke et al. NATURE REVIEWS NEUROSCIENCE
- Axonal transport deficits and neurodegenerative diseases
- (2013) Stéphanie Millecamps et al. NATURE REVIEWS NEUROSCIENCE
- Genetic analysis of SS18L1 in French amyotrophic lateral sclerosis
- (2013) Elisa Teyssou et al. NEUROBIOLOGY OF AGING
- Global Epidemiology of Amyotrophic Lateral Sclerosis: A Systematic Review of the Published Literature
- (2013) A. Chiò et al. NEUROEPIDEMIOLOGY
- Mutations in the gene encoding p62 in Japanese patients with amyotrophic lateral sclerosis
- (2013) M. Hirano et al. NEUROLOGY
- Unconventional Translation of C9ORF72 GGGGCC Expansion Generates Insoluble Polypeptides Specific to c9FTD/ALS
- (2013) Peter E.A. Ash et al. NEURON
- RNA Toxicity from the ALS/FTD C9ORF72 Expansion Is Mitigated by Antisense Intervention
- (2013) Christopher J. Donnelly et al. NEURON
- PARP-1 dependent recruitment of the amyotrophic lateral sclerosis-associated protein FUS/TLS to sites of oxidative DNA damage
- (2013) Stuart L. Rulten et al. NUCLEIC ACIDS RESEARCH
- Molecular Imaging of Microglial Activation in Amyotrophic Lateral Sclerosis
- (2013) Philippe Corcia et al. PLoS One
- Genome-Wide Copy Number Variation in Sporadic Amyotrophic Lateral Sclerosis in the Turkish Population: Deletion of EPHA3 Is a Possible Protective Factor
- (2013) Özgün Uyan et al. PLoS One
- Targeted degradation of sense and antisense C9orf72 RNA foci as therapy for ALS and frontotemporal degeneration
- (2013) C. Lagier-Tourenne et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- ALS-linked TDP-43 mutations produce aberrant RNA splicing and adult-onset motor neuron disease without aggregation or loss of nuclear TDP-43
- (2013) E. S. Arnold et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Targeting RNA Foci in iPSC-Derived Motor Neurons from ALS Patients with a C9ORF72 Repeat Expansion
- (2013) D. Sareen et al. Science Translational Medicine
- Prion-like Properties of Pathological TDP-43 Aggregates from Diseased Brains
- (2013) Takashi Nonaka et al. Cell Reports
- Hexanucleotide Repeats in ALS/FTD Form Length-Dependent RNA Foci, Sequester RNA Binding Proteins, and Are Neurotoxic
- (2013) Youn-Bok Lee et al. Cell Reports
- ALS-Associated FUS Mutations Result in Compromised FUS Alternative Splicing and Autoregulation
- (2013) Yueqin Zhou et al. PLoS Genetics
- Gain-of-function mutations in the ALS8 causative gene VAPB have detrimental effects on neurons and muscles
- (2013) M. Sanhueza et al. Biology Open
- Overexpression of human wild-type FUS causes progressive motor neuron degeneration in an age- and dose-dependent fashion
- (2012) Jacqueline C. Mitchell et al. ACTA NEUROPATHOLOGICA
- Replication of association of CHRNA4 rare variants with sporadic amyotrophic lateral sclerosis: The Italian multicentre study
- (2012) Mario Sabatelli et al. Amyotrophic Lateral Sclerosis
- Non-human primate model of amyotrophic lateral sclerosis with cytoplasmic mislocalization of TDP-43
- (2012) Azusa Uchida et al. BRAIN
- A patient-derived stem cell model of hereditary spastic paraplegia with SPAST mutations
- (2012) G. Abrahamsen et al. Disease Models & Mechanisms
- Autoregulation of TDP-43 mRNA levels involves interplay between transcription, splicing, and alternative polyA site selection
- (2012) S. E. Avendano-Vazquez et al. GENES & DEVELOPMENT
- Evaluating the role of the FUS/TLS-related gene EWSR1 in amyotrophic lateral sclerosis
- (2012) Julien Couthouis et al. HUMAN MOLECULAR GENETICS
- C19orf12 mutations in neurodegeneration with brain iron accumulation mimicking juvenile amyotrophic lateral sclerosis
- (2012) M. Deschauer et al. JOURNAL OF NEUROLOGY
- Ubiquilin 2mutations in Italian patients with amyotrophic lateral sclerosis and frontotemporal dementia
- (2012) Cinzia Gellera et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- Cellular reprogramming to reset epigenetic signatures
- (2012) Kyle J. Hewitt et al. MOLECULAR ASPECTS OF MEDICINE
- Expression of Fused in sarcoma mutations in mice recapitulates the neuropathology of FUS proteinopathies and provides insight into disease pathogenesis
- (2012) Christophe Verbeeck et al. Molecular Neurodegeneration
- Oligodendroglia metabolically support axons and contribute to neurodegeneration
- (2012) Youngjin Lee et al. NATURE
- Mutations in the profilin 1 gene cause familial amyotrophic lateral sclerosis
- (2012) Chi-Hong Wu et al. NATURE
- EPHA4 is a disease modifier of amyotrophic lateral sclerosis in animal models and in humans
- (2012) Annelies Van Hoecke et al. NATURE MEDICINE
- Divergent roles of ALS-linked proteins FUS/TLS and TDP-43 intersect in processing long pre-mRNAs
- (2012) Clotilde Lagier-Tourenne et al. NATURE NEUROSCIENCE
- De novo FUS gene mutations are associated with juvenile-onset sporadic amyotrophic lateral sclerosis in China
- (2012) Zhang-Yu Zou et al. NEUROBIOLOGY OF AGING
- SQSTM1 mutations in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
- (2012) E. Rubino et al. NEUROLOGY
- Knockdown of the Drosophila Fused in Sarcoma (FUS) Homologue Causes Deficient Locomotive Behavior and Shortening of Motoneuron Terminal Branches
- (2012) Hiroshi Sasayama et al. PLoS One
- Ataxin-2-Like Is a Regulator of Stress Granules and Processing Bodies
- (2012) Christian Kaehler et al. PLoS One
- FUS-NLS/Transportin 1 Complex Structure Provides Insights into the Nuclear Targeting Mechanism of FUS and the Implications in ALS
- (2012) Chunyan Niu et al. PLoS One
- Mutant induced pluripotent stem cell lines recapitulate aspects of TDP-43 proteinopathies and reveal cell-specific vulnerability
- (2012) B. Bilican et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Drug Screening for ALS Using Patient-Specific Induced Pluripotent Stem Cells
- (2012) N. Egawa et al. Science Translational Medicine
- Concise Review: Patient-Derived Olfactory Stem Cells: New Models for Brain Diseases
- (2012) Alan Mackay-Sim STEM CELLS
- C9orf72 hexanucleotide repeat associated with amyotrophic lateral sclerosis and frontotemporal dementia forms RNA G-quadruplexes
- (2012) Pietro Fratta et al. Scientific Reports
- Mutational analysis reveals the FUS homolog TAF15 as a candidate gene for familial amyotrophic lateral sclerosis
- (2011) N. Ticozzi et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS
- A mutation in sigma-1 receptor causes juvenile amyotrophic lateral sclerosis
- (2011) Amr Al-Saif et al. ANNALS OF NEUROLOGY
- SQSTM1 Mutations in Familial and Sporadic Amyotrophic Lateral Sclerosis
- (2011) Faisal Fecto ARCHIVES OF NEUROLOGY
- Altered Cell Cycle Dynamics in Schizophrenia
- (2011) Yongjun Fan et al. BIOLOGICAL PSYCHIATRY
- FET proteins TAF15 and EWS are selective markers that distinguish FTLD with FUS pathology from amyotrophic lateral sclerosis with FUS mutations
- (2011) Manuela Neumann et al. BRAIN
- Modelling the Effects of Penetrance and Family Size on Rates of Sporadic and Familial Disease
- (2011) Ammar Al-Chalabi et al. HUMAN HEREDITY
- A non-invasive method to isolate the neuronal linage from the nasal epithelium from schizophrenic and bipolar diseases
- (2011) G. Benítez-King et al. JOURNAL OF NEUROSCIENCE METHODS
- The Ewing Sarcoma Protein Regulates DNA Damage-Induced Alternative Splicing
- (2011) Maria Paola Paronetto et al. MOLECULAR CELL
- Human Senataxin Resolves RNA/DNA Hybrids Formed at Transcriptional Pause Sites to Promote Xrn2-Dependent Termination
- (2011) Konstantina Skourti-Stathaki et al. MOLECULAR CELL
- Expression of mutant TDP-43 induces neuronal dysfunction in transgenic mice
- (2011) Ya-Fei Xu et al. Molecular Neurodegeneration
- MicroRNA-mediated conversion of human fibroblasts to neurons
- (2011) Andrew S. Yoo et al. NATURE
- Mutations in UBQLN2 cause dominant X-linked juvenile and adult-onset ALS and ALS/dementia
- (2011) Han-Xiang Deng et al. NATURE
- Induction of human neuronal cells by defined transcription factors
- (2011) Zhiping P. Pang et al. NATURE
- Characterizing the RNA targets and position-dependent splicing regulation by TDP-43
- (2011) James R Tollervey et al. NATURE NEUROSCIENCE
- A novel heterozygous nonsense mutation of the OPTN gene segregating in a Danish family with ALS
- (2011) Zeynep Tümer et al. NEUROBIOLOGY OF AGING
- Exome sequencing reveals SPG11 mutations causing juvenile ALS
- (2011) Hussein Daoud et al. NEUROBIOLOGY OF AGING
- UNC13A is a modifier of survival in amyotrophic lateral sclerosis
- (2011) Frank P. Diekstra et al. NEUROBIOLOGY OF AGING
- Expanded GGGGCC Hexanucleotide Repeat in Noncoding Region of C9ORF72 Causes Chromosome 9p-Linked FTD and ALS
- (2011) Mariely DeJesus-Hernandez et al. NEURON
- A Hexanucleotide Repeat Expansion in C9ORF72 Is the Cause of Chromosome 9p21-Linked ALS-FTD
- (2011) Alan E. Renton et al. NEURON
- NRF2 Activation Restores Disease Related Metabolic Deficiencies in Olfactory Neurosphere-Derived Cells from Patients with Sporadic Parkinson's Disease
- (2011) Anthony L. Cook et al. PLoS One
- A yeast functional screen predicts new candidate ALS disease genes
- (2011) J. Couthouis et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- FUS Transgenic Rats Develop the Phenotypes of Amyotrophic Lateral Sclerosis and Frontotemporal Lobar Degeneration
- (2011) Cao Huang et al. PLoS Genetics
- Loss of murine TDP-43 disrupts motor function and plays an essential role in embryogenesis
- (2010) Brian C. Kraemer et al. ACTA NEUROPATHOLOGICA
- A randomized, placebo-controlled trial of memantine for functional disability in amyotrophic lateral sclerosis
- (2010) Mamede de Carvalho et al. Amyotrophic Lateral Sclerosis
- Senataxin mutations and amyotrophic lateral sclerosis
- (2010) Michio Hirano et al. Amyotrophic Lateral Sclerosis
- Paraoxonase gene mutations in amyotrophic lateral sclerosis
- (2010) Nicola Ticozzi et al. ANNALS OF NEUROLOGY
- Sigma nonopioid intracellular receptor 1 mutations cause frontotemporal lobar degeneration-motor neuron disease
- (2010) Agnes A. Luty et al. ANNALS OF NEUROLOGY
- SPATACSIN mutations cause autosomal recessive juvenile amyotrophic lateral sclerosis
- (2010) A. Orlacchio et al. BRAIN
- A Review of the Neural Mechanisms of Action and Clinical Efficiency of Riluzole in Treating Amyotrophic Lateral Sclerosis: What have we Learned in the Last Decade?
- (2010) Mark C. Bellingham CNS Neuroscience & Therapeutics
- Neurotoxic effects of TDP-43 overexpression in C. elegans
- (2010) Peter E.A. Ash et al. HUMAN MOLECULAR GENETICS
- Disruption of endocytic trafficking in frontotemporal dementia with CHMP2B mutations
- (2010) Hazel Urwin et al. HUMAN MOLECULAR GENETICS
- An estimate of amyotrophic lateral sclerosis heritability using twin data
- (2010) A. Al-Chalabi et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- Phosphorylation Promotes Neurotoxicity in a Caenorhabditis elegans Model of TDP-43 Proteinopathy
- (2010) N. F. Liachko et al. JOURNAL OF NEUROSCIENCE
- Neuronal biomarkers from patients with mental illnesses: a novel method through nasal biopsy combined with laser-captured microdissection
- (2010) K Tajinda et al. MOLECULAR PSYCHIATRY
- Myelination and support of axonal integrity by glia
- (2010) Klaus-Armin Nave NATURE
- Ataxin-2 intermediate-length polyglutamine expansions are associated with increased risk for ALS
- (2010) Andrew C. Elden et al. NATURE
- Mutations of optineurin in amyotrophic lateral sclerosis
- (2010) Hirofumi Maruyama et al. NATURE
- A novel peripherin gene (PRPH) mutation identified in one sporadic amyotrophic lateral sclerosis patient
- (2010) Lucia Corrado et al. NEUROBIOLOGY OF AGING
- Progressive motor weakness in transgenic mice expressing human TDP-43
- (2010) Nancy R. Stallings et al. NEUROBIOLOGY OF DISEASE
- Exome Sequencing Reveals VCP Mutations as a Cause of Familial ALS
- (2010) Janel O. Johnson et al. NEURON
- AMPA receptor-mediated neuronal death in sporadic ALS
- (2010) Shin Kwak et al. NEUROPATHOLOGY
- Mutations in CHMP2B in Lower Motor Neuron Predominant Amyotrophic Lateral Sclerosis (ALS)
- (2010) Laura E. Cox et al. PLoS One
- Novel Antibodies Reveal Inclusions Containing Non-Native SOD1 in Sporadic ALS Patients
- (2010) Karin Forsberg et al. PLoS One
- Olfactory Stem Cells, a New Cellular Model for Studying Molecular Mechanisms Underlying Familial Dysautonomia
- (2010) Nathalie Boone et al. PLoS One
- Structural basis for the wobbler mouse neurodegenerative disorder caused by mutation in the Vps54 subunit of the GARP complex
- (2010) F. J. Perez-Victoria et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Deletion of TDP-43 down-regulates Tbc1d1, a gene linked to obesity, and alters body fat metabolism
- (2010) P.-M. Chiang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Familial amyotrophic lateral sclerosis is associated with a mutation in D-amino acid oxidase
- (2010) J. Mitchell et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Deficits in axonal transport precede ALS symptoms in vivo
- (2010) L. G. Bilsland et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- TDP-43 transgenic mice develop spastic paralysis and neuronal inclusions characteristic of ALS and frontotemporal lobar degeneration
- (2010) Hans Wils et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The multiple roles of TDP-43 in pre-mRNA processing and gene expression regulation
- (2010) Emanuele Buratti et al. RNA Biology
- Oligodendrocytes: biology and pathology
- (2009) Monika Bradl et al. ACTA NEUROPATHOLOGICA
- Deleterious Variants of FIG4, a Phosphoinositide Phosphatase, in Patients with ALS
- (2009) Clement Y. Chow et al. AMERICAN JOURNAL OF HUMAN GENETICS
- A phase II trial of talampanel in subjects with amyotrophic lateral sclerosis
- (2009) Robert M. Pascuzzi et al. Amyotrophic Lateral Sclerosis
- Prognostic factors in ALS: A critical review
- (2009) Adriano Chiò et al. Amyotrophic Lateral Sclerosis
- Recognition and Processing of Ubiquitin-Protein Conjugates by the Proteasome
- (2009) Daniel Finley Annual Review of Biochemistry
- Oligomerization of Mutant SOD1 in Mitochondria of Motoneuronal Cells Drives Mitochondrial Damage and Cell Toxicity
- (2009) Mauro Cozzolino et al. ANTIOXIDANTS & REDOX SIGNALING
- TDP-43 Redistribution is an Early Event in Sporadic Amyotrophic Lateral Sclerosis
- (2009) Maria Teresa Giordana et al. BRAIN PATHOLOGY
- TDP-43, a neuro-pathosignature factor, is essential for early mouse embryogenesis
- (2009) Lien-Szu Wu et al. GENESIS
- Rare missense variants of neuronal nicotinic acetylcholine receptor altering receptor function are associated with sporadic amyotrophic lateral sclerosis
- (2009) M. Sabatelli et al. HUMAN MOLECULAR GENETICS
- Gain and loss of function of ALS-related mutations of TARDBP (TDP-43) cause motor deficits in vivo
- (2009) Edor Kabashi et al. HUMAN MOLECULAR GENETICS
- Molecular Neuropathology of TDP-43 Proteinopathies
- (2009) Manuela Neumann INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- TDP-43 Is a Developmentally Regulated Protein Essential for Early Embryonic Development
- (2009) Chantelle F. Sephton et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Finding the missing heritability of complex diseases
- (2009) Teri A. Manolio et al. NATURE
- A large-scale international meta-analysis of paraoxonase gene polymorphisms in sporadic ALS
- (2009) A. -M. Wills et al. NEUROLOGY
- A novel form of juvenile recessive ALS maps to loci on 6p25 and 21q22
- (2009) Russell J. Butterfield et al. NEUROMUSCULAR DISORDERS
- Mutations in FUS, an RNA Processing Protein, Cause Familial Amyotrophic Lateral Sclerosis Type 6
- (2009) C. Vance et al. SCIENCE
- Mutations in the FUS/TLS Gene on Chromosome 16 Cause Familial Amyotrophic Lateral Sclerosis
- (2009) T. J. Kwiatkowski et al. SCIENCE
- Neuropathy Target Esterase Gene Mutations Cause Motor Neuron Disease
- (2008) Shirley Rainier et al. AMERICAN JOURNAL OF HUMAN GENETICS
- A common haplotype within the PON1 promoter region is associated with sporadic ALS
- (2008) John E. Landers et al. Amyotrophic Lateral Sclerosis
- TDP-43mutation in familial amyotrophic lateral sclerosis
- (2008) Akio Yokoseki et al. ANNALS OF NEUROLOGY
- TDP-43A315T mutation in familial motor neuron disease
- (2008) Michael A. Gitcho et al. ANNALS OF NEUROLOGY
- Development of a High-Throughput Microarray-Based Resequencing System for Neurological Disorders and Its Application to Molecular Genetics of Amyotrophic Lateral Sclerosis
- (2008) Yuji Takahashi et al. ARCHIVES OF NEUROLOGY
- Features of trinucleotide repeat instability in vivo
- (2008) Irina V Kovtun et al. CELL RESEARCH
- Variants of the elongator protein 3 ( ELP3 ) gene are associated with motor neuron degeneration
- (2008) Claire L. Simpson et al. HUMAN MOLECULAR GENETICS
- Structural determinants of the cellular localization and shuttling of TDP-43
- (2008) Y. M. Ayala et al. JOURNAL OF CELL SCIENCE
- Anterior horn cells with abnormal TDP-43 immunoreactivities show fragmentation of the Golgi apparatus in ALS
- (2008) Yukio Fujita et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
- Progranulin (PGRN) expression in ALS: An immunohistochemical study
- (2008) D. Irwin et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
- TARDBP mutations in amyotrophic lateral sclerosis with TDP-43 neuropathology: a genetic and histopathological analysis
- (2008) Vivianna M Van Deerlin et al. LANCET NEUROLOGY
- TARDBP mutations in individuals with sporadic and familial amyotrophic lateral sclerosis
- (2008) Edor Kabashi et al. NATURE GENETICS
- Association of paraoxonase gene cluster polymorphisms with ALS in France, Quebec, and Sweden
- (2008) P. N. Valdmanis et al. NEUROLOGY
- Wobbler mice modeling motor neuron disease display elevated transactive response DNA binding protein
- (2008) J.S. Dennis et al. NEUROSCIENCE
- TDP-43 Mutations in Familial and Sporadic Amyotrophic Lateral Sclerosis
- (2008) J. Sreedharan et al. SCIENCE
- Simple sequence repeats: genetic modulators of brain function and behavior
- (2008) John W. Fondon et al. TRENDS IN NEUROSCIENCES
- Novel Mutations in TARDBP (TDP-43) in Patients with Familial Amyotrophic Lateral Sclerosis
- (2008) Nicola J. Rutherford et al. PLoS Genetics
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started