期刊
ANNALS OF NEUROLOGY
卷 68, 期 1, 页码 102-107出版社
WILEY
DOI: 10.1002/ana.21993
关键词
-
资金
- ALS Therapy Alliance
- Angel Fund
- Pierre L. de Bourgknecht ALS Research Foundation
- Al-Athel ALS Research Foundation
- ALS Family Charitable Foundation
- Packard Center for ALS Research
- American Academy of Neurology Foundation/ALS Association
- National Institute of Neurological Disorders and Stroke [IRO1NS050557-03]
- NIH National Institute of Environmental Health Sciences [RO1ES09883-04A2]
- Italian Ministry of Health [ex Art.56, n.533F/N1, RF2007/INN644440]
- Peviani family
Three clustered, homologous paraoxonase genes (PON1, PON2, and PON3) have roles in preventing lipid oxidation and detoxifying organophosphates. Recent reports describe a genetic association between the PON genes and sporadic amyotrophic lateral sclerosis (ALS). We now report that in genomic DNA from individuals with familial and sporadic ALS, we have identified at least 7 PON gene mutations that are predicted to alter PON function. ANN NEUROL 2010;68:102-107
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据
分享论文
