West Nile virus capsid protein inhibits autophagy by AMP-activated protein kinase degradation in neurological disease development

Direct Activation of Adenosine Monophosphate-Activated Protein Kinase (AMPK) by PF-06409577 Inhibits Flavivirus Infection through Modification of Host Cell Lipid Metabolism

(2018) Nereida Jiménez de Oya et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

A novel reverse genetics system for production of infectious West Nile virus using homologous recombination in mammalian cells

(2017) Shintaro Kobayashi et al.   JOURNAL OF VIROLOGICAL METHODS

Valosin-containing protein (VCP/p97) plays a role in the replication of West Nile virus

(2017) Wallaya Phongphaew et al.   VIRUS RESEARCH

E3 Ubiquitin Ligase Nedd4 Promotes Japanese Encephalitis Virus Replication by Suppressing Autophagy in Human Neuroblastoma Cells

(2017) Qingqiang Xu et al.   Scientific Reports

DENV up-regulates the HMG-CoA reductase activity through the impairment of AMPK phosphorylation: A potential antiviral target

(2017) Rubén Soto-Acosta et al.   PLoS Pathogens

Rab8b Regulates Transport of West Nile Virus Particles from Recycling Endosomes

(2016) Shintaro Kobayashi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The ubiquitin-proteasome system is essential for the productive entry of Japanese encephalitis virus

(2016) Shaobo Wang et al.   VIROLOGY

Analysis of the role of autophagy inhibition by two complementary human cytomegalovirus BECN1/Beclin 1-binding proteins

(2015) Lina Mouna et al.   Autophagy

Degradation of AMPK by a Cancer-Specific Ubiquitin Ligase

(2015) Carlos T. Pineda et al.   CELL

In vitro growth, pathogenicity and serological characteristics of the Japanese encephalitis virus genotype V Muar strain

(2015) Shigeru Tajima et al.   JOURNAL OF GENERAL VIROLOGY

The Pathogenesis of 3 Neurotropic Flaviviruses in a Mouse Model Depends on the Route of Neuroinvasion After Viremia

(2015) Noriyo Nagata et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

A Japanese Encephalitis Virus Genotype 5 Molecular Clone Is Highly Neuropathogenic in a Mouse Model: Impact of the Structural Protein Region on Virulence

(2015) Mélissanne de Wispelaere et al.   JOURNAL OF VIROLOGY

Autophagy inhibits viral genome replication and gene expression stages in West Nile virus infection

(2014) Shintaro Kobayashi et al.   VIRUS RESEARCH

Autophagy and Viruses: Adversaries or Allies?

(2013) Xiaonan Dong et al.   Journal of Innate Immunity

Autophagosomes form at ER–mitochondria contact sites

(2013) Maho Hamasaki et al.   NATURE

Identification of a candidate therapeutic autophagy-inducing peptide

(2013) Sanae Shoji-Kawata et al.   NATURE

Cysteine Residues in the Major Capsid Protein, Vp1, of the JC Virus Are Important for Protein Stability and Oligomer Formation

(2013) Shintaro Kobayashi et al.   PLoS One

Genetic Screens in Human Cells Using the CRISPR-Cas9 System

(2013) Tim Wang et al.   SCIENCE

AMPK-dependent phosphorylation of ULK1 regulates ATG9 localization

(2012) Hildegard I.D. Mack et al.   Autophagy

In vivo imaging of proteasome inhibition using a proteasome-sensitive fluorescent reporter

(2012) Isao Momose et al.   CANCER SCIENCE

Regulation of AMPK by the Ubiquitin Proteasome System

(2011) Makhosazane Zungu et al.   AMERICAN JOURNAL OF PATHOLOGY

Accumulation of ubiquitinated proteins is related to West Nile virus-induced neuronal apoptosis

(2011) Shintaro Kobayashi et al.   NEUROPATHOLOGY

Multiple Aggregates and Aggresomes of C-Terminal Truncated Human αA-Crystallins in Mammalian Cells and Protection by αB-Crystallin

(2011) Ilangovan Raju et al.   PLoS One

Beclin-1 Targeting for Viral Immune Escape

(2011) Christian Münz   Viruses-Basel

Novel Cell- and Tissue-Based Assays for Detecting Misfolded and Aggregated Protein Accumulation Within Aggresomes and Inclusion Bodies

(2010) Dee Shen et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Ubiquitin accumulation in autophagy-deficient mice is dependent on the Nrf2-mediated stress response pathway: a potential role for protein aggregation in autophagic substrate selection

(2010) Brigit E. Riley et al.   JOURNAL OF CELL BIOLOGY

Autophagy, antiviral immunity, and viral countermeasures

(2009) Sanae Shoji-Kawata et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Autophagy pathway intersects with HIV-1 biosynthesis and regulates viral yields in macrophages

(2009) George B. Kyei et al.   JOURNAL OF CELL BIOLOGY

Autophagy and viral neurovirulence

(2008) Anthony Orvedahl et al.   CELLULAR MICROBIOLOGY

Autophagy fights disease through cellular self-digestion

(2008) Noboru Mizushima et al.   NATURE

Disruption of Neuronal Autophagy by Infected Microglia Results in Neurodegeneration

(2008) Mehrdad Alirezaei et al.   PLoS One