标题
Structure guided prediction of Pyrazinamide resistance mutations in pncA
作者
关键词
-
出版物
Scientific Reports
Volume 10, Issue 1, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2020-02-05
DOI
10.1038/s41598-020-58635-x
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Underestimated pyrazinamide resistance may compromise outcomes of pyrazinamide containing regimens for treatment of drug susceptible and multi-drug-resistant tuberculosis in Tanzania
- (2019) Saumu Pazia Juma et al. BMC INFECTIOUS DISEASES
- Empirical ways to identify novel Bedaquiline resistance mutations in AtpE
- (2019) Malancha Karmakar et al. PLoS One
- Analysis of a Novel pncA Mutation for Susceptibility to Pyrazinamide Therapy
- (2018) Malancha Karmakar et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- NGL viewer: web-based molecular graphics for large complexes
- (2018) Alexander S Rose et al. BIOINFORMATICS
- Frequent transmission of the Mycobacterium tuberculosis Beijing lineage and positive selection for the EsxW Beijing variant in Vietnam
- (2018) Kathryn E. Holt et al. NATURE GENETICS
- DynaMut: predicting the impact of mutations on protein conformation, flexibility and stability
- (2018) Carlos HM Rodrigues et al. NUCLEIC ACIDS RESEARCH
- Prediction of Susceptibility to First-Line Tuberculosis Drugs by DNA Sequencing
- (2018) NEW ENGLAND JOURNAL OF MEDICINE
- Understanding molecular consequences of putative drug resistant mutations in Mycobacterium tuberculosis
- (2018) Stephanie Portelli et al. Scientific Reports
- A standardised method for interpreting the association between mutations and phenotypic drug resistance in Mycobacterium tuberculosis
- (2017) Paolo Miotto et al. EUROPEAN RESPIRATORY JOURNAL
- Combating mutations in genetic disease and drug resistance: understanding molecular mechanisms to guide drug design
- (2017) Amanda T.S. Albanaz et al. Expert Opinion on Drug Discovery
- Arpeggio: A Web Server for Calculating and Visualising Interatomic Interactions in Protein Structures
- (2017) Harry C Jubb et al. JOURNAL OF MOLECULAR BIOLOGY
- A comprehensive characterization of PncA polymorphisms that confer resistance to pyrazinamide
- (2017) Adam N. Yadon et al. Nature Communications
- Genetic Determinants of Drug Resistance inMycobacterium tuberculosisand Their Diagnostic Value
- (2016) Maha R. Farhat et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Missense mutations in the unfoldase ClpC1 of the caseinolytic protease complex are associated with pyrazinamide resistance in Mycobacterium tuberculosis
- (2016) Michelle Yee et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Mycobacterium tuberculosis whole genome sequencing and protein structure modelling provides insights into anti-tuberculosis drug resistance
- (2016) Jody Phelan et al. BMC Medicine
- CSM-lig: a web server for assessing and comparing protein–small molecule affinities
- (2016) Douglas E.V. Pires et al. NUCLEIC ACIDS RESEARCH
- Variation in Human Cytochrome P-450 Drug-Metabolism Genes: A Gateway to the Understanding of Plasmodium vivax Relapses
- (2016) Ana Carolina Rios Silvino et al. PLoS One
- mCSM-lig: quantifying the effects of mutations on protein-small molecule affinity in genetic disease and emergence of drug resistance
- (2016) Douglas E. V. Pires et al. Scientific Reports
- The Presence, Persistence and Functional Properties of Plasmodium vivax Duffy Binding Protein II Antibodies Are Influenced by HLA Class II Allelic Variants
- (2016) Flora S. Kano et al. PLoS Neglected Tropical Diseases
- The Inosine Monophosphate Dehydrogenase, GuaB2, Is a Vulnerable New Bactericidal Drug Target for Tuberculosis
- (2016) Vinayak Singh et al. ACS Infectious Diseases
- Essential but Not Vulnerable: Indazole Sulfonamides Targeting Inosine Monophosphate Dehydrogenase as Potential Leads against Mycobacterium tuberculosis
- (2016) Yumi Park et al. ACS Infectious Diseases
- In silico functional dissection of saturation mutagenesis: Interpreting the relationship between phenotypes and changes in protein stability, interactions and activity
- (2016) Douglas E. V. Pires et al. Scientific Reports
- Better prediction of functional effects for sequence variants
- (2015) Maximilian Hecht et al. BMC GENOMICS
- Mycobacterium tuberculosispncAPolymorphisms That Do Not Confer Pyrazinamide Resistance at a Breakpoint Concentration of 100 Micrograms per Milliliter in MGIT: TABLE 1
- (2015) Michael G. Whitfield et al. JOURNAL OF CLINICAL MICROBIOLOGY
- Mycobacterial DNA Extraction for Whole-Genome Sequencing from Early Positive Liquid (MGIT) Cultures
- (2015) Antonina A. Votintseva et al. JOURNAL OF CLINICAL MICROBIOLOGY
- Efficiency and safety of the combination of moxifloxacin, pretomanid (PA-824), and pyrazinamide during the first 8 weeks of antituberculosis treatment: a phase 2b, open-label, partly randomised trial in patients with drug-susceptible or drug-resistant pulmonary tuberculosis
- (2015) Rodney Dawson et al. LANCET
- Genome-wide Mycobacterium tuberculosis variation (GMTV) database: a new tool for integrating sequence variations and epidemiology
- (2014) Ekaterina N Chernyaeva et al. BMC GENOMICS
- DUET: a server for predicting effects of mutations on protein stability using an integrated computational approach
- (2014) D. E. V. Pires et al. NUCLEIC ACIDS RESEARCH
- Mycobacterium tuberculosis Pyrazinamide Resistance Determinants: a Multicenter Study
- (2014) P. Miotto et al. mBio
- Potent hepatitis C inhibitors bind directly to NS5A and reduce its affinity for RNA
- (2014) David B. Ascher et al. Scientific Reports
- Aspartate decarboxylase (PanD) as a new target of pyrazinamide in Mycobacterium tuberculosis
- (2014) Wanliang Shi et al. Emerging Microbes & Infections
- mCSM: predicting the effects of mutations in proteins using graph-based signatures
- (2013) Douglas E. V. Pires et al. BIOINFORMATICS
- Proficiency of drug susceptibility testing of Mycobacterium tuberculosis against pyrazinamide: the Swedish experience
- (2013) S. Hoffner et al. INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE
- Systematic Analysis of Pyrazinamide-Resistant Spontaneous Mutants and Clinical Isolates of Mycobacterium tuberculosis
- (2012) Karolien Stoffels et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Predicting the Functional Effect of Amino Acid Substitutions and Indels
- (2012) Yongwook Choi et al. PLoS One
- Routine Use of Microbial Whole Genome Sequencing in Diagnostic and Public Health Microbiology
- (2012) Claudio U. Köser et al. PLoS Pathogens
- Pyrazinamide Susceptibility Testing in Mycobacterium tuberculosis: a Systematic Review with Meta-Analyses
- (2011) Kwok Chiu Chang et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Validation of pncA Gene Sequencing in Combination with the Mycobacterial Growth Indicator Tube Method To Test Susceptibility of Mycobacterium tuberculosis to Pyrazinamide
- (2011) S. O. Simons et al. JOURNAL OF CLINICAL MICROBIOLOGY
- SDM--a server for predicting effects of mutations on protein stability and malfunction
- (2011) C. L. Worth et al. NUCLEIC ACIDS RESEARCH
- Crystal Structure of the Pyrazinamidase of Mycobacterium tuberculosis: Insights into Natural and Acquired Resistance to Pyrazinamide
- (2011) Stéphanie Petrella et al. PLoS One
- Pyrazinamide Inhibits Trans-Translation in Mycobacterium tuberculosis
- (2011) W. Shi et al. SCIENCE
- Potential for Erroneous Results Indicating Resistance When Using the Bactec MGIT 960 System for Testing Susceptibility ofMycobacterium tuberculosisto Pyrazinamide
- (2009) Pamela Chedore et al. JOURNAL OF CLINICAL MICROBIOLOGY
- Characterisation of pncA mutations in clinical Mycobacterium tuberculosis isolates in New Zealand
- (2009) Sushil Pandey et al. PATHOLOGY
- Tuberculosis Drug Resistance Mutation Database
- (2009) Andreas Sandgren et al. PLOS MEDICINE
- A Once-Weekly R207910-containing Regimen Exceeds Activity of the Standard Daily Regimen in Murine Tuberculosis
- (2008) Nicolas Veziris et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now