Metformin-induced suppression of IFN-α via mTORC1 signalling following seasonal vaccination is associated with impaired antibody responses in type 2 diabetes
出版年份 2020 全文链接
标题
Metformin-induced suppression of IFN-α via mTORC1 signalling following seasonal vaccination is associated with impaired antibody responses in type 2 diabetes
作者
关键词
-
出版物
Scientific Reports
Volume 10, Issue 1, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2020-02-24
DOI
10.1038/s41598-020-60213-0
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Antibody Responses to Influenza A/H1N1pdm09 Virus After Pandemic and Seasonal Influenza Vaccination in Healthcare Workers: A 5-Year Follow-up Study
- (2018) Mai-Chi Trieu et al. CLINICAL INFECTIOUS DISEASES
- IDF Diabetes Atlas: Global estimates of diabetes prevalence for 2017 and projections for 2045
- (2018) N.H. Cho et al. DIABETES RESEARCH AND CLINICAL PRACTICE
- Metformin and Autoimmunity: A “New Deal” of an Old Drug
- (2018) Francesco Ursini et al. Frontiers in Immunology
- Glibenclamide Reduces Primary Human Monocyte Functions Against Tuberculosis Infection by Enhancing M2 Polarization
- (2018) Chidchamai Kewcharoenwong et al. Frontiers in Immunology
- The double burden of diabetes and global infection in low and middle-income countries
- (2018) Susanna Dunachie et al. TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE
- Germinal Center Selection and Affinity Maturation Require Dynamic Regulation of mTORC1 Kinase
- (2017) Jonatan Ersching et al. IMMUNITY
- Boosting of post-exposure human T-cell and B-cell recall responsesin vivobyBurkholderia pseudomallei-related proteins
- (2017) Arnone Nithichanon et al. IMMUNOLOGY
- Type I interferon signaling is required for the APOBEC3/Rfv3-dependent neutralizing antibody response but not innate retrovirus restriction
- (2017) Bradley S. Barrett et al. Retrovirology
- Benefits of flu vaccination for persons with diabetes mellitus: A review
- (2017) M. Goeijenbier et al. VACCINE
- Influenza Virus and Glycemic Variability in Diabetes: A Killer Combination?
- (2017) Katina D. Hulme et al. Frontiers in Microbiology
- NETosis before and after Hyperglycemic Control in Type 2 Diabetes Mellitus Patients
- (2017) Agostina Carestia et al. PLoS One
- Anti-Inflammatory Effects of Metformin Irrespective of Diabetes StatusNovelty and Significance
- (2016) Amy R. Cameron et al. CIRCULATION RESEARCH
- Diabetes Care: “Taking It to the Limit One More Time”
- (2016) William T. Cefalu et al. DIABETES CARE
- Whole-Virion Influenza Vaccine Recalls an Early Burst of High-Affinity Memory B Cell Response through TLR Signaling
- (2016) Taishi Onodera et al. JOURNAL OF IMMUNOLOGY
- A systems study reveals concurrent activation of AMPK and mTOR by amino acids
- (2016) Piero Dalle Pezze et al. Nature Communications
- mTOR Regulation of Lymphoid Cells in Immunity to Pathogens
- (2016) Rachael Keating et al. Frontiers in Immunology
- Glibenclamide impairs responses of neutrophils against Burkholderia pseudomallei by reduction of intracellular glutathione
- (2016) Chidchamai Kewcharoenwong et al. Scientific Reports
- Long-Term Immunogenicity and Safety of a Conventional Influenza Vaccine in Patients with Type 2 Diabetes
- (2015) Yu Bin Seo et al. Clinical and Vaccine Immunology
- Systems Analysis of Immunity to Influenza Vaccination across Multiple Years and in Diverse Populations Reveals Shared Molecular Signatures
- (2015) Helder I. Nakaya et al. IMMUNITY
- The antibody response to influenza vaccination is not impaired in type 2 diabetics
- (2015) Patricia A. Sheridan et al. VACCINE
- Peering into the Crystal Ball: Influenza Pandemics and Vaccine Efficacy
- (2014) Matthew S. Miller et al. CELL
- Global Analyses of Human Immune Variation Reveal Baseline Predictors of Postvaccination Responses
- (2014) John S. Tsang et al. CELL
- Host-directed therapy of tuberculosis based on interleukin-1 and type I interferon crosstalk
- (2014) Katrin D. Mayer-Barber et al. NATURE
- Immunogenicity of influenza A(H1N1)pdm09 vaccine in patients with diabetes mellitus
- (2014) Yumi Egawa et al. Human Vaccines & Immunotherapeutics
- B Cell-Specific Deficiencies in mTOR Limit Humoral Immune Responses
- (2013) S. Zhang et al. JOURNAL OF IMMUNOLOGY
- B Cell-Intrinsic TLR7 Signaling Is Required for Optimal B Cell Responses during Chronic Viral Infection
- (2013) J. M. Clingan et al. JOURNAL OF IMMUNOLOGY
- Toll-like receptor 3 and RIG-I-like receptor activation induces innate antiviral responses in mouse ovarian granulosa cells
- (2013) Keqin Yan et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- The kinase mTOR modulates the antibody response to provide cross-protective immunity to lethal infection with influenza virus
- (2013) Rachael Keating et al. NATURE IMMUNOLOGY
- Updates of mTOR Inhibitors
- (2012) Hongyu Zhou et al. Anti-Cancer Agents in Medicinal Chemistry
- HI responses induced by seasonal influenza vaccination are associated with clinical protection and with seroprotection against non-homologous strains
- (2012) Willem Luytjes et al. VACCINE
- Cellular and molecular mechanisms of metformin: an overview
- (2011) Benoit Viollet et al. CLINICAL SCIENCE
- Programming the magnitude and persistence of antibody responses with innate immunity
- (2011) Sudhir Pai Kasturi et al. NATURE
- Toll-like Receptor 7 Controls the Anti-Retroviral Germinal Center Response
- (2011) Edward P. Browne PLoS Pathogens
- Advances in the vaccination of the elderly against influenza: role of a high-dose vaccine
- (2010) Seth J Sullivan et al. Expert Review of Vaccines
- Systems Vaccinology
- (2010) Bali Pulendran et al. IMMUNITY
- Interferon-α and -β in kidney inflammation
- (2010) Hans-Joachim Anders et al. KIDNEY INTERNATIONAL
- Plasmacytoid Dendritic Cells Delineate Immunogenicity of Influenza Vaccine Subtypes
- (2010) S. Koyama et al. Science Translational Medicine
- Safety, immunogencity, and efficacy of a cold-adapted A/Ann Arbor/6/60 (H2N2) vaccine in mice and ferrets
- (2009) Grace L. Chen et al. VIROLOGY
- The Pathology of Influenza Virus Infections
- (2008) Jeffery K. Taubenberger et al. Annual Review of Pathology-Mechanisms of Disease
- PI3K is critical for the nuclear translocation of IRF-7 and type I IFN production by human plasmacytoid predendritic cells in response to TLR activation
- (2008) Cristiana Guiducci et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Translational control of the innate immune response through IRF-7
- (2008) Rodney Colina et al. NATURE
- RAPping production of type I interferon in pDCs through mTOR
- (2008) Mauro Costa-Mattioli et al. NATURE IMMUNOLOGY
- Toll-like receptor–mediated induction of type I interferon in plasmacytoid dendritic cells requires the rapamycin-sensitive PI(3)K-mTOR-p70S6K pathway
- (2008) Weiping Cao et al. NATURE IMMUNOLOGY
- Role of the Akt pathway in mRNA translation of interferon-stimulated genes
- (2008) S. Kaur et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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