DeepRiPP integrates multiomics data to automate discovery of novel ribosomally synthesized natural products
出版年份 2019 全文链接
标题
DeepRiPP integrates multiomics data to automate discovery of novel ribosomally synthesized natural products
作者
关键词
-
出版物
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 117, Issue 1, Pages 371-380
出版商
Proceedings of the National Academy of Sciences
发表日期
2019-12-24
DOI
10.1073/pnas.1901493116
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Evaluation of strategies for the assembly of diverse bacterial genomes using MinION long-read sequencing
- (2019) Sarah Goldstein et al. BMC GENOMICS
- Bioinformatic Expansion and Discovery of Thiopeptide Antibiotics
- (2018) Christopher J. Schwalen et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Novel soil bacteria possess diverse genes for secondary metabolite biosynthesis
- (2018) Alexander Crits-Christoph et al. NATURE
- A primer on deep learning in genomics
- (2018) James Zou et al. NATURE GENETICS
- The antiSMASH database version 2: a comprehensive resource on secondary metabolite biosynthetic gene clusters
- (2018) Kai Blin et al. NUCLEIC ACIDS RESEARCH
- A new genome-mining tool redefines the lasso peptide biosynthetic landscape
- (2017) Jonathan I Tietz et al. Nature Chemical Biology
- RiPPMiner: a bioinformatics resource for deciphering chemical structures of RiPPs based on prediction of cleavage and cross-links
- (2017) Priyesh Agrawal et al. NUCLEIC ACIDS RESEARCH
- PRISM 3: expanded prediction of natural product chemical structures from microbial genomes
- (2017) Michael A. Skinnider et al. NUCLEIC ACIDS RESEARCH
- antiSMASH 4.0—improvements in chemistry prediction and gene cluster boundary identification
- (2017) Kai Blin et al. NUCLEIC ACIDS RESEARCH
- Comparative analysis of chemical similarity methods for modular natural products with a hypothetical structure enumeration algorithm
- (2017) Michael A. Skinnider et al. Journal of Cheminformatics
- Natural Products as Sources of New Drugs from 1981 to 2014
- (2016) David J. Newman et al. JOURNAL OF NATURAL PRODUCTS
- Deep learning for computational biology
- (2016) Christof Angermueller et al. Molecular Systems Biology
- New tools for reconstruction and heterologous expression of natural product biosynthetic gene clusters
- (2016) Yunzi Luo et al. NATURAL PRODUCT REPORTS
- Polyketide and nonribosomal peptide retro-biosynthesis and global gene cluster matching
- (2016) Chris A Dejong et al. Nature Chemical Biology
- Assembly and clustering of natural antibiotics guides target identification
- (2016) Chad W Johnston et al. Nature Chemical Biology
- Dereplication of peptidic natural products through database search of mass spectra
- (2016) Hosein Mohimani et al. Nature Chemical Biology
- Genomic charting of ribosomally synthesized natural product chemical space facilitates targeted mining
- (2016) Michael A. Skinnider et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Exploration of Nonribosomal Peptide Families with an Automated Informatic Search Algorithm
- (2015) Lian Yang et al. CHEMISTRY & BIOLOGY
- Regulating malonyl-CoA metabolism via synthetic antisense RNAs for enhanced biosynthesis of natural products
- (2015) Yaping Yang et al. METABOLIC ENGINEERING
- Predicting the sequence specificities of DNA- and RNA-binding proteins by deep learning
- (2015) Babak Alipanahi et al. NATURE BIOTECHNOLOGY
- Computational approaches to natural product discovery
- (2015) Marnix H Medema et al. Nature Chemical Biology
- Genomes to natural products PRediction Informatics for Secondary Metabolomes (PRISM)
- (2015) Michael A. Skinnider et al. NUCLEIC ACIDS RESEARCH
- An automated Genomes-to-Natural Products platform (GNP) for the discovery of modular natural products
- (2015) Chad W. Johnston et al. Nature Communications
- Automated Genome Mining of Ribosomal Peptide Natural Products
- (2014) Hosein Mohimani et al. ACS Chemical Biology
- Nucleophilic 1,4-Additions for Natural Product Discovery
- (2014) Courtney L. Cox et al. ACS Chemical Biology
- Insights into Secondary Metabolism from a Global Analysis of Prokaryotic Biosynthetic Gene Clusters
- (2014) Peter Cimermancic et al. CELL
- Automated Identification of Depsipeptide Natural Products by an Informatic Search Algorithm
- (2014) Michael A. Skinnider et al. CHEMBIOCHEM
- NRPquest: Coupling Mass Spectrometry and Genome Mining for Nonribosomal Peptide Discovery
- (2014) Hosein Mohimani et al. JOURNAL OF NATURAL PRODUCTS
- A roadmap for natural product discovery based on large-scale genomics and metabolomics
- (2014) James R Doroghazi et al. Nature Chemical Biology
- Heterologous Expression of the Thiopeptide Antibiotic GE2270 from Planobispora rosea ATCC 53733 in Streptomyces coelicolor Requires Deletion of Ribosomal Genes from the Expression Construct
- (2014) Katrin Flinspach et al. PLoS One
- Structural investigation of ribosomally synthesized natural products by hypothetical structure enumeration and evaluation using tandem MS
- (2014) Q. Zhang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Pep2Path: Automated Mass Spectrometry-Guided Genome Mining of Peptidic Natural Products
- (2014) Marnix H. Medema et al. PLoS Computational Biology
- Genome mining of the Streptomyces avermitilis genome and development of genome-minimized hosts for heterologous expression of biosynthetic gene clusters
- (2013) Haruo Ikeda et al. JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY
- MS/MS networking guided analysis of molecule and gene cluster families
- (2013) D. D. Nguyen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- PKMiner: a database for exploring type II polyketide synthases
- (2012) Jinki Kim et al. BMC MICROBIOLOGY
- Antibiotics: A New Hope
- (2012) Gerard D. Wright CHEMISTRY & BIOLOGY
- Sequential deletion of all the polyketide synthase and nonribosomal peptide synthetase biosynthetic gene clusters and a 900-kb subtelomeric sequence of the linear chromosome of Streptomyces coelicolor
- (2012) Min Zhou et al. FEMS MICROBIOLOGY LETTERS
- Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature
- (2012) Paul G. Arnison et al. NATURAL PRODUCT REPORTS
- DoBISCUIT: a database of secondary metabolite biosynthetic gene clusters
- (2012) Natsuko Ichikawa et al. NUCLEIC ACIDS RESEARCH
- ClusterMine360: a database of microbial PKS/NRPS biosynthesis
- (2012) Kyle R. Conway et al. NUCLEIC ACIDS RESEARCH
- The Natural Product Domain Seeker NaPDoS: A Phylogeny Based Bioinformatic Tool to Classify Secondary Metabolite Gene Diversity
- (2012) Nadine Ziemert et al. PLoS One
- Dereplicating nonribosomal peptides using an informatic search algorithm for natural products (iSNAP) discovery
- (2012) A. Ibrahim et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A mass spectrometry–guided genome mining approach for natural product peptidogenomics
- (2011) Roland D Kersten et al. Nature Chemical Biology
- Genome-minimized Streptomyces host for the heterologous expression of secondary metabolism
- (2010) M. Komatsu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Catalytic promiscuity in the biosynthesis of cyclic peptide secondary metabolites in planktonic marine cyanobacteria
- (2010) B. Li et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Automated genome mining for natural products
- (2009) Michael HT Li et al. BMC BIOINFORMATICS
- Drug Discovery and Natural Products: End of an Era or an Endless Frontier?
- (2009) J. W.-H. Li et al. SCIENCE
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now