标题
Gliotransmission: A Novel Target for the Development of Antiseizure Drugs
作者
关键词
-
出版物
NEUROSCIENTIST
Volume -, Issue -, Pages 107385842090147
出版商
SAGE Publications
发表日期
2020-01-24
DOI
10.1177/1073858420901474
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- The role of astrocytic glutamate transporters GLT-1 and GLAST in neurological disorders: Potential targets for neurotherapeutics
- (2019) Edward Pajarillo et al. NEUROPHARMACOLOGY
- Pharmacoresistance – Epidemiology, mechanisms, and impact on epilepsy treatment
- (2019) Mubeen Janmohamed et al. NEUROPHARMACOLOGY
- Safety and efficacy of adjunctive cenobamate (YKP3089) in patients with uncontrolled focal seizures: a multicentre, double-blind, randomised, placebo-controlled, dose-response trial
- (2019) Gregory L Krauss et al. LANCET NEUROLOGY
- Interictal regional paroxysmal fast activity on scalp EEG is common in patients with underlying gliosis
- (2018) Gopal Krishna Dash et al. CLINICAL NEUROPHYSIOLOGY
- Epidemiologist’s view: Addressing the epilepsy surgery treatment gap with minimally-invasive techniques
- (2018) Nicholas K. Schiltz et al. EPILEPSY RESEARCH
- Role of Purinergic Receptor P2Y1 in Spatiotemporal Ca2+Dynamics in Astrocytes
- (2018) Eiji Shigetomi et al. JOURNAL OF NEUROSCIENCE
- Purinergic modulation of glutamate transmission: An expanding role in stress-linked neuropathology
- (2018) J. Mayhew et al. NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
- Pannexin-1 channels contribute to seizure generation in human epileptic brain tissue and in a mouse model of epilepsy
- (2018) Elena Dossi et al. Science Translational Medicine
- Ca2+ Signals in Astrocytes Facilitate Spread of Epileptiform Activity
- (2018) Kjell Heuser et al. CEREBRAL CORTEX
- Progress report on new antiepileptic drugs: A summary of the Fourteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XIV). I. Drugs in preclinical and early clinical development
- (2018) Meir Bialer et al. EPILEPSIA
- Investigational small molecules in phase II clinical trials for the treatment of epilepsy
- (2018) Marco Greco et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
- Blocking TNFα-driven astrocyte purinergic signaling restores normal synaptic activity during epileptogenesis
- (2018) Ljiljana Nikolic et al. GLIA
- Astroglial Ca2+-Dependent Hyperexcitability Requires P2Y1 Purinergic Receptors and Pannexin-1 Channel Activation in a Chronic Model of Epilepsy
- (2018) Mario Wellmann et al. Frontiers in Cellular Neuroscience
- Altered hippocampal interneuron activity precedes ictal onset
- (2018) Mitra L Miri et al. eLife
- Expression and function of the metabotropic purinergic P2Y receptor family in experimental seizure models and patients with drug-refractory epilepsy
- (2017) Mariana Alves et al. EPILEPSIA
- Subcellular reorganization and altered phosphorylation of the astrocytic gap junction protein connexin43 in human and experimental temporal lobe epilepsy
- (2017) Tushar Deshpande et al. GLIA
- Region-specific deletions of the glutamate transporter GLT1 differentially affect seizure activity and neurodegeneration in mice
- (2017) Junya Sugimoto et al. GLIA
- Selective Silencing of Hippocampal Parvalbumin Interneurons Induces Development of Recurrent Spontaneous Limbic Seizures in Mice
- (2017) Meinrad Drexel et al. JOURNAL OF NEUROSCIENCE
- Animal Models of Seizures and Epilepsy: Past, Present, and Future Role for the Discovery of Antiseizure Drugs
- (2017) Wolfgang Löscher NEUROCHEMICAL RESEARCH
- The National Institute of Neurological Disorders and Stroke (NINDS) Epilepsy Therapy Screening Program (ETSP)
- (2017) John H. Kehne et al. NEUROCHEMICAL RESEARCH
- Histopathological Findings in Brain Tissue Obtained during Epilepsy Surgery
- (2017) Ingmar Blumcke et al. NEW ENGLAND JOURNAL OF MEDICINE
- Role of the purinergic signaling in epilepsy
- (2017) Marek Cieślak et al. Pharmacological Reports
- Transformation of Astrocytes to a Neuroprotective Phenotype by Microglia via P2Y 1 Receptor Downregulation
- (2017) Youichi Shinozaki et al. Cell Reports
- Drug-Resistant Epilepsy: Multiple Hypotheses, Few Answers
- (2017) Fei Tang et al. Frontiers in Neurology
- Anti-Epileptic Drug Combination Efficacy in an In Vitro Seizure Model – Phenytoin and Valproate, Lamotrigine and Valproate
- (2017) Kim Det Taing et al. PLoS One
- ABC Transporters and Drug Resistance in Patients with Epilepsy
- (2016) Maria Feldmann et al. CURRENT PHARMACEUTICAL DESIGN
- Transient P2X7 Receptor Antagonism Produces Lasting Reductions in Spontaneous Seizures and Gliosis in Experimental Temporal Lobe Epilepsy
- (2016) Alba Jimenez-Pacheco et al. JOURNAL OF NEUROSCIENCE
- Brivaracetam add-on for refractory focal epilepsy
- (2016) Simona Lattanzi et al. NEUROLOGY
- Crucial role of astrocytes in temporal lobe epilepsy
- (2016) C. Steinhäuser et al. NEUROSCIENCE
- Active dendrites regulate the impact of gliotransmission on rat hippocampal pyramidal neurons
- (2016) Sufyan Ashhad et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Activity-dependent switch of GABAergic inhibition into glutamatergic excitation in astrocyte-neuron networks
- (2016) Gertrudis Perea et al. eLife
- Plasticity of Hippocampal Excitatory-Inhibitory Balance: Missing the Synaptic Control in the Epileptic Brain
- (2016) Christian Bonansco et al. NEURAL PLASTICITY
- NMDA receptor NR2B subunits contribute to PTZ-kindling-induced hippocampal astrocytosis and oxidative stress
- (2015) Xinjian Zhu et al. BRAIN RESEARCH BULLETIN
- Perampanel: A Review in Drug-Resistant Epilepsy
- (2015) James E. Frampton DRUGS
- Enhanced astroglial Ca2+signaling increases excitatory synaptic strength in the epileptic brain
- (2015) Carla Álvarez-Ferradas et al. GLIA
- The inhibitory neurotransmitter GABA evokes long-lasting Ca2+oscillations in cortical astrocytes
- (2015) Letizia Mariotti et al. GLIA
- Parvalbumin-Positive Inhibitory Interneurons Oppose Propagation But Favor Generation of Focal Epileptiform Activity
- (2015) M. Sessolo et al. JOURNAL OF NEUROSCIENCE
- Activation of calcineurin underlies altered trafficking of α2 subunit containing GABAA receptors during prolonged epileptiform activity
- (2015) Ramona Eckel et al. NEUROPHARMACOLOGY
- Increased extracellular levels of glutamate in the hippocampus of chronically epileptic rats
- (2015) M. Soukupova et al. NEUROSCIENCE
- MTLE with hippocampal sclerosis in adult as a syndrome
- (2015) M. Baulac REVUE NEUROLOGIQUE
- Exocytosis of gliotransmitters from cortical astrocytes: implications for synaptic plasticity and aging
- (2014) Ulyana Lalo et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Connexons and pannexons: newcomers in neurophysiology
- (2014) Giselle Cheung et al. Frontiers in Cellular Neuroscience
- A new rapid kindling variant for induction of cortical epileptogenesis in freely moving rats
- (2014) Juan Carlos Morales et al. Frontiers in Cellular Neuroscience
- Contribution of Aberrant GluK2-Containing Kainate Receptors to Chronic Seizures in Temporal Lobe Epilepsy
- (2014) Angélique Peret et al. Cell Reports
- Increased neocortical expression of the P2X7 receptor after status epilepticus and anticonvulsant effect of P2X7 receptor antagonist A-438079
- (2013) Alba Jimenez-Pacheco et al. EPILEPSIA
- Astrocyte calcium signaling and epilepsy
- (2012) Giorgio Carmignoto et al. GLIA
- Astrocytes Mediate In Vivo Cholinergic-Induced Synaptic Plasticity
- (2012) Marta Navarrete et al. PLOS BIOLOGY
- Astrocytes Are Endogenous Regulators of Basal Transmission at Central Synapses
- (2011) Aude Panatier et al. CELL
- Kindling-induced asymmetric accumulation of hippocampal 7S SNARE complexes correlates with enhanced glutamate release
- (2011) Elena A. Matveeva et al. EPILEPSIA
- Glutamate released spontaneously from astrocytes sets the threshold for synaptic plasticity
- (2011) Christian Bonansco et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Functional contributions of astrocytes in synchronization of a neuronal network model
- (2011) Mahmood Amiri et al. JOURNAL OF THEORETICAL BIOLOGY
- Targeting Pannexin1 Improves Seizure Outcome
- (2011) Marcelo F. Santiago et al. PLoS One
- Microglia activation triggers astrocyte-mediated modulation of excitatory neurotransmission
- (2011) O. Pascual et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Critical review of current animal models of seizures and epilepsy used in the discovery and development of new antiepileptic drugs
- (2011) Wolfgang Löscher SEIZURE-EUROPEAN JOURNAL OF EPILEPSY
- Astrocytic function and its alteration in the epileptic brain
- (2010) Ronald Jabs et al. EPILEPSIA
- Glutamate and GABA in the balance: Convergent pathways sustain seizures during status epilepticus
- (2010) David E. Naylor EPILEPSIA
- Glia-Dependent Switch of Kainate Receptor Presynaptic Action
- (2010) V. D. J. Bonfardin et al. JOURNAL OF NEUROSCIENCE
- Selective induction of astrocytic gliosis generates deficits in neuronal inhibition
- (2010) Pavel I Ortinski et al. NATURE NEUROSCIENCE
- An Excitatory Loop with Astrocytes Contributes to Drive Neurons to Seizure Threshold
- (2010) Marta Gómez-Gonzalo et al. PLOS BIOLOGY
- Excitatory amino acid transporters EAAT-1 and EAAT-2 in temporal lobe and hippocampus in intractable temporal lobe epilepsy
- (2009) SINAN SARAC et al. APMIS
- Different phases of afterdischarge during rapid kindling procedure in mice
- (2009) Alberto E. Musto et al. EPILEPSY RESEARCH
- Subunit-Specific Trafficking of GABAA Receptors during Status Epilepticus
- (2008) H. P. Goodkin et al. JOURNAL OF NEUROSCIENCE
- The pilocarpine model of temporal lobe epilepsy
- (2008) Giulia Curia et al. JOURNAL OF NEUROSCIENCE METHODS
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started