标题
Cannabinoids and the expanded endocannabinoid system in neurological disorders
作者
关键词
-
出版物
Nature Reviews Neurology
Volume 16, Issue 1, Pages 9-29
出版商
Springer Science and Business Media LLC
发表日期
2019-12-13
DOI
10.1038/s41582-019-0284-z
参考文献
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Transient Receptor Potential Vanilloid 1 Modulates Central Inflammation in Multiple Sclerosis
- (2019) Mario Stampanoni Bassi et al. Frontiers in Neurology
- The Expanded Endocannabinoid System/Endocannabinoidome as a Potential Target for Treating Diabetes Mellitus
- (2019) Alain Veilleux et al. Current Diabetes Reports
- Oleoylethanolamide increases the expression of PPAR-Α and reduces appetite and body weight in obese people: A clinical trial
- (2018) Payahoo Laleh et al. APPETITE
- Antibiotic-induced microbiota perturbation causes gut endocannabinoidome changes, hippocampal neuroglial reorganization and depression in mice
- (2018) F. Guida et al. BRAIN BEHAVIOR AND IMMUNITY
- The Pharmacokinetics and the Pharmacodynamics of Cannabinoids
- (2018) C.J. Lucas et al. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
- Cannabidiol exerts antiepileptic effects by restoring hippocampal interneuron functions in a temporal lobe epilepsy model
- (2018) Archie A Khan et al. BRITISH JOURNAL OF PHARMACOLOGY
- Allosteric modulators of cannabinoid receptor 1: developing compounds for improved specificity
- (2018) Rachel Dopart et al. DRUG METABOLISM REVIEWS
- Open-label use of Highly* purified CBD (Epidiolex®) in patients with CDKL5 deficiency disorder and Aicardi, Dup15q, and Doose syndromes
- (2018) Orrin Devinsky et al. EPILEPSY & BEHAVIOR
- Clinical response to Nabiximols correlates with the downregulation of immune pathways in multiple sclerosis
- (2018) M. Sorosina et al. EUROPEAN JOURNAL OF NEUROLOGY
- Investigational cannabinoids in seizure disorders, what have we learned thus far?
- (2018) Dejana Ružić Zečević et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
- Sativex® as Add-on therapy Vs. further optimized first-line ANTispastics (SAVANT) in resistant multiple sclerosis spasticity: a double-blind, placebo-controlled randomised clinical trial
- (2018) Jolana Markovà et al. INTERNATIONAL JOURNAL OF NEUROSCIENCE
- Cannabinoid CB2 receptors in the mouse brain: relevance for Alzheimer’s disease
- (2018) Alicia López et al. Journal of Neuroinflammation
- Cannabidiol in patients with seizures associated with Lennox-Gastaut syndrome (GWPCARE4): a randomised, double-blind, placebo-controlled phase 3 trial
- (2018) Elizabeth A Thiele et al. LANCET
- Surprising outcomes in cannabinoid CB1/CB2 receptor double knockout mice in two models of ischemia
- (2018) Sara Jane Ward et al. LIFE SCIENCES
- Anticonvulsive effects of endocannabinoids; an investigation to determine the role of regulatory components of endocannabinoid metabolism in the Pentylenetetrazol induced tonic- clonic seizures
- (2018) Parisa Zareie et al. METABOLIC BRAIN DISEASE
- The expression of cannabinoid type 1 receptor and 2-arachidonoyl glycerol synthesizing/degrading enzymes is altered in basal ganglia during the active phase of levodopa-induced dyskinesia
- (2018) Estefania Rojo-Bustamante et al. NEUROBIOLOGY OF DISEASE
- Astroglial CB 1 Receptors Determine Synaptic D-Serine Availability to Enable Recognition Memory
- (2018) Laurie M. Robin et al. NEURON
- N -Oleoyl-glycine reduces nicotine reward and withdrawal in mice
- (2018) Giulia Donvito et al. NEUROPHARMACOLOGY
- Cannabinoid CB1 and CB2 Receptors, and Monoacylglycerol Lipase Gene Expression Alterations in the Basal Ganglia of Patients with Parkinson’s Disease
- (2018) Francisco Navarrete et al. Neurotherapeutics
- Palmitoylethanolamide Dampens Reactive Astrogliosis and Improves Neuronal Trophic Support in a Triple Transgenic Model of Alzheimer’s Disease: In Vitro and In Vivo Evidence
- (2018) Maria Rosanna Bronzuoli et al. Oxidative Medicine and Cellular Longevity
- Early alteration of distribution and activity of hippocampal type-1 cannabinoid receptor in Alzheimer’s disease-like mice overexpressing the human mutant amyloid precursor protein
- (2018) Mauro Maccarrone et al. PHARMACOLOGICAL RESEARCH
- Analysis of endocannabinoid receptors and enzymes in the post-mortem motor cortex and spinal cord of amyotrophic lateral sclerosis patients
- (2018) Francisco Espejo-Porras et al. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration
- Emerging strategies targeting CB 2 cannabinoid receptor: Biased agonism and allosterism
- (2018) Paula Morales et al. BIOCHEMICAL PHARMACOLOGY
- Gut microbiota, cannabinoid system and neuroimmune interactions: New perspectives in multiple sclerosis
- (2018) L. Mestre et al. BIOCHEMICAL PHARMACOLOGY
- Cannabinoid pharmacology/therapeutics in chronic degenerative disorders affecting the central nervous system
- (2018) Maria S. Aymerich et al. BIOCHEMICAL PHARMACOLOGY
- Cannabidiol improves frequency and severity of seizures and reduces adverse events in an open-label add-on prospective study
- (2018) Jerzy P. Szaflarski et al. EPILEPSY & BEHAVIOR
- Resolution of inflammation is altered in chronic heart failure and entails a dysfunctional responsiveness of T lymphocytes
- (2018) Valerio Chiurchiù et al. FASEB JOURNAL
- CB2 Cannabinoid Receptor Agonist Ameliorates Alzheimer-Like Phenotype in AβPP/PS1 Mice
- (2018) Ester Aso et al. JOURNAL OF ALZHEIMERS DISEASE
- Type-1 Cannabinoid Receptor Activity During Alzheimer's Disease Progression
- (2018) Iván Manuel et al. JOURNAL OF ALZHEIMERS DISEASE
- Cannabis-Based Medicine Reduces Multiple Pathological Processes in AβPP/PS1 Mice
- (2018) Ester Aso et al. JOURNAL OF ALZHEIMERS DISEASE
- Long-Term Cannabidiol Treatment Prevents the Development of Social Recognition Memory Deficits in Alzheimer's Disease Transgenic Mice
- (2018) David Cheng et al. JOURNAL OF ALZHEIMERS DISEASE
- New approaches and challenges to targeting the endocannabinoid system
- (2018) Vincenzo Di Marzo NATURE REVIEWS DRUG DISCOVERY
- Medical cannabis: A needs analysis for people with epilepsy
- (2018) Arti Kerai et al. Complementary Therapies in Clinical Practice
- Emerging Role of Diet and Microbiota Interactions in Neuroinflammation
- (2018) Mathangi Janakiraman et al. Frontiers in Immunology
- The level of evidence of medical marijuana use for treating disabilities: a scoping review
- (2018) Nichole Stetten et al. DISABILITY AND REHABILITATION
- Inhibition of Transient Receptor Potential Vanilloid 1 Attenuates Blood–Brain Barrier Disruption after Traumatic Brain Injury in Mice
- (2018) Dian-xu Yang et al. JOURNAL OF NEUROTRAUMA
- Invited Review: From nose to gut – the role of the microbiome in neurological disease
- (2018) J. S. Bell et al. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY
- Interactions between cannabidiol and commonly used antiepileptic drugs
- (2017) Tyler E. Gaston et al. EPILEPSIA
- Anti-excitotoxic effects of cannabidiol are partly mediated by enhancement of NCX2 and NCX3 expression in animal model of cerebral ischemia
- (2017) Sepideh Khaksar et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Preliminary Evidence on Cannabis Effectiveness and Tolerability for Adults With Tourette Syndrome
- (2017) Elia Abi-Jaoude et al. JOURNAL OF NEUROPSYCHIATRY AND CLINICAL NEUROSCIENCES
- Inhibition of Endocannabinoid Degradation Improves Outcomes from Mild Traumatic Brain Injury: A Mechanistic Role for Synaptic Hyperexcitability
- (2017) Jacques Mayeux et al. JOURNAL OF NEUROTRAUMA
- Alleviation of Neuropathology by Inhibition of Monoacylglycerol Lipase in APP Transgenic Mice Lacking CB2 Receptors
- (2017) Jian Zhang et al. MOLECULAR NEUROBIOLOGY
- Commensal bacteria make GPCR ligands that mimic human signalling molecules
- (2017) Louis J. Cohen et al. NATURE
- Cannabidiol reduces brain damage and improves functional recovery in a neonatal rat model of arterial ischemic stroke
- (2017) Maria Ceprián et al. NEUROPHARMACOLOGY
- Evaluation of monoacylglycerol lipase as a therapeutic target in a transgenic mouse model of ALS
- (2017) Noemi Pasquarelli et al. NEUROPHARMACOLOGY
- Synaptic functions of endocannabinoid signaling in health and disease
- (2017) Alfonso Araque et al. NEUROPHARMACOLOGY
- Trial of Cannabidiol for Drug-Resistant Seizures in the Dravet Syndrome
- (2017) Orrin Devinsky et al. NEW ENGLAND JOURNAL OF MEDICINE
- Regulation of gut luminal serotonin by commensal microbiota in mice
- (2017) Tomokazu Hata et al. PLoS One
- Cannabidiol attenuates seizures and social deficits in a mouse model of Dravet syndrome
- (2017) Joshua S. Kaplan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cannabinoid CB2 receptor ligand profiling reveals biased signalling and off-target activity
- (2017) Marjolein Soethoudt et al. Nature Communications
- A randomised controlled cross-over double-blind pilot study protocol on THC:CBD oromucosal spray efficacy as an add-on therapy for post-stroke spasticity
- (2017) Lucio Marinelli et al. BMJ Open
- Cannabinoid Receptor 2 Signaling in Neurodegenerative Disorders: From Pathogenesis to a Promising Therapeutic Target
- (2017) Tommaso Cassano et al. Frontiers in Neuroscience
- Sativex in the management of multiple sclerosis-related spasticity: An overview of the last decade of clinical evaluation
- (2017) Sabrina Giacoppo et al. Multiple Sclerosis and Related Disorders
- Blockade of CB1 cannabinoid receptor alters gut microbiota and attenuates inflammation and diet-induced obesity
- (2017) Pegah Mehrpouya-Bahrami et al. Scientific Reports
- Gut-brain Axis: Role of Lipids in the Regulation of Inflammation, Pain and CNS Diseases
- (2017) Roberto Russo et al. CURRENT MEDICINAL CHEMISTRY
- Upper motor neuron evaluation in multiple sclerosis patients treated with Sativex®
- (2016) A. Carotenuto et al. ACTA NEUROLOGICA SCANDINAVICA
- GABA production and structure of gadB / gadC genes in Lactobacillus and Bifidobacterium strains from human microbiota
- (2016) R.A. Yunes et al. ANAEROBE
- Fatty acid amide hydrolase inhibition for the symptomatic relief of Parkinson’s disease
- (2016) Marta Celorrio et al. BRAIN BEHAVIOR AND IMMUNITY
- CB1 receptor antagonism prevents long-term hyperexcitability after head injury by regulation of dynorphin-KOR system and mGluR5 in rat hippocampus
- (2016) Xiu Wang et al. BRAIN RESEARCH
- The pharmacology of palmitoylethanolamide and first data on the therapeutic efficacy of some of its new formulations
- (2016) Stefania Petrosino et al. BRITISH JOURNAL OF PHARMACOLOGY
- The Role of the Endocannabinoid System in the Brain–Gut Axis
- (2016) Keith A. Sharkey et al. GASTROENTEROLOGY
- Gingival Stromal Cells as an In Vitro Model: Cannabidiol Modulates Genes Linked With Amyotrophic Lateral Sclerosis
- (2016) Thangavelu Soundara Rajan et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Cannabidiol as a Potential Treatment for Febrile Infection-Related Epilepsy Syndrome (FIRES) in the Acute and Chronic Phases
- (2016) Jacqueline S. Gofshteyn et al. JOURNAL OF CHILD NEUROLOGY
- Development and Pharmacological Characterization of Selective Blockers of 2-Arachidonoyl Glycerol Degradation with Efficacy in Rodent Models of Multiple Sclerosis and Pain
- (2016) Margherita Brindisi et al. JOURNAL OF MEDICINAL CHEMISTRY
- A double-blind, randomized, cross-over, placebo-controlled, pilot trial with Sativex in Huntington’s disease
- (2016) Jose Luis López-Sendón Moreno et al. JOURNAL OF NEUROLOGY
- Efficacy and safety of cannabinoid oromucosal spray for multiple sclerosis spasticity
- (2016) F Patti et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- Effects of tetrahydrocannabinol on balance and gait in patients with dementia: A randomised controlled crossover trial
- (2016) Geke AH van den Elsen et al. JOURNAL OF PSYCHOPHARMACOLOGY
- Cannabidiol in patients with treatment-resistant epilepsy: an open-label interventional trial
- (2016) Orrin Devinsky et al. LANCET NEUROLOGY
- Allosteric Modulation: An Alternate Approach Targeting the Cannabinoid CB1 Receptor
- (2016) Thuy Nguyen et al. MEDICINAL RESEARCH REVIEWS
- A cannabinoid link between mitochondria and memory
- (2016) Etienne Hebert-Chatelain et al. NATURE
- Cannabinoid Type 2 Receptors Mediate a Cell Type-Specific Plasticity in the Hippocampus
- (2016) A. Vanessa Stempel et al. NEURON
- Oral Palmitoylethanolamide Treatment Is Associated with Reduced Cutaneous Adverse Effects of Interferon-β1a and Circulating Proinflammatory Cytokines in Relapsing–Remitting Multiple Sclerosis
- (2016) Nicola S. Orefice et al. Neurotherapeutics
- Modulation of monocytes by bioactive lipid anandamide in multiple sclerosis involves distinct Toll-like receptors
- (2016) Valerio Chiurchiù et al. PHARMACOLOGICAL RESEARCH
- Orexin-A represses satiety-inducing POMC neurons and contributes to obesity via stimulation of endocannabinoid signaling
- (2016) Giovanna Morello et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Acetylcholine receptors from human muscle as pharmacological targets for ALS therapy
- (2016) Eleonora Palma et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Potential of the cannabinoid CB2 receptor as a pharmacological target against inflammation in Parkinson's disease
- (2016) Yolanda Gómez-Gálvez et al. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
- Therapeutic potential of cannabis-related drugs
- (2016) Stephen P.H. Alexander PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
- Tetrahydrocannabinol in Behavioral Disturbances in Dementia: A Crossover Randomized Controlled Trial
- (2015) Geke A.H. van den Elsen et al. AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY
- Chronic oleoylethanolamide treatment improves spatial cognitive deficits through enhancing hippocampal neurogenesis after transient focal cerebral ischemia
- (2015) Li-chao Yang et al. BIOCHEMICAL PHARMACOLOGY
- The role of cannabinoids in adult neurogenesis
- (2015) Jack A Prenderville et al. BRITISH JOURNAL OF PHARMACOLOGY
- Palmitoylethanolamide attenuates PTZ-induced seizures through CB1 and CB2 receptors
- (2015) Iraj Aghaei et al. EPILEPSY RESEARCH
- Attenuation of kainic acid-induced status epilepticus by inhibition of endocannabinoid transport and degradation in guinea pigs
- (2015) Liubov Shubina et al. EPILEPSY RESEARCH
- Increased tonic cannabinoid CB1R activity and brain region-specific desensitization of CB1R Gi/o signaling axis in mice with global genetic knockout of monoacylglycerol lipase
- (2015) Dina Navia-Paldanius et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Cannabidiol stimulates Aml-1a-dependent glial differentiation and inhibits glioma stem-like cells proliferation by inducing autophagy in a TRPV2-dependent manner
- (2015) Massimo Nabissi et al. INTERNATIONAL JOURNAL OF CANCER
- Genetic deletion of monoacylglycerol lipase leads to impaired cannabinoid receptor CB1R signaling and anxiety-like behavior
- (2015) Roberta Imperatore et al. JOURNAL OF NEUROCHEMISTRY
- Changes in the endocannabinoid signaling system in CNS structures of TDP-43 transgenic mice: relevance for a neuroprotective therapy in TDP-43-related disorders
- (2015) Francisco Espejo-Porras et al. Journal of Neuroimmune Pharmacology
- Monoacylglycerol lipase inhibitor JZL184 reduces neuroinflammatory response in APdE9 mice and in adult mouse glial cells
- (2015) Rea Pihlaja et al. Journal of Neuroinflammation
- Endocannabinoid Degradation Inhibition Improves Neurobehavioral Function, Blood–Brain Barrier Integrity, and Neuroinflammation following Mild Traumatic Brain Injury
- (2015) Paige S. Katz et al. JOURNAL OF NEUROTRAUMA
- Anti-carcinogenic activity of anandamide on human glioma in vitro and in vivo
- (2015) CHAO MA et al. Molecular Medicine Reports
- Hypothalamic POMC neurons promote cannabinoid-induced feeding
- (2015) Marco Koch et al. NATURE
- Endocannabinoids — at the crossroads between the gut microbiota and host metabolism
- (2015) Patrice D. Cani et al. Nature Reviews Endocrinology
- Endocannabinoid regulation of amyloid-induced neuroinflammation
- (2015) Carmen Vázquez et al. NEUROBIOLOGY OF AGING
- Post-status epilepticus treatment with the cannabinoid agonist WIN 55,212-2 prevents chronic epileptic hippocampal damage in rats
- (2015) Roberto Di Maio et al. NEUROBIOLOGY OF DISEASE
- Tetrahydrocannabinol for neuropsychiatric symptoms in dementia: A randomized controlled trial
- (2015) G. A. H. van den Elsen et al. NEUROLOGY
- Chronic cannabinoid receptor stimulation selectively prevents motor impairments in a mouse model of Huntington's disease
- (2015) Susanna Pietropaolo et al. NEUROPHARMACOLOGY
- Activation of CB2 receptor is required for the therapeutic effect of ABHD6 inhibition in experimental autoimmune encephalomyelitis
- (2015) Jie Wen et al. NEUROPHARMACOLOGY
- Interaction between the protective effects of cannabidiol and palmitoylethanolamide in experimental model of multiple sclerosis in C57BL/6 mice
- (2015) A. Rahimi et al. NEUROSCIENCE
- Long-term disease-modifying effect of the endocannabinoid agonist WIN55,212-2 in a rat model of audiogenic epilepsy
- (2015) Lyudmila V. Vinogradova et al. Pharmacological Reports
- Involvement of PPAR receptors in the anticonvulsant effects of a cannabinoid agonist, WIN 55,212-2
- (2015) Borna Payandemehr et al. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
- Alternatively activated microglia and macrophages in the central nervous system
- (2015) Rafael Franco et al. PROGRESS IN NEUROBIOLOGY
- Adipose tissue NAPE-PLD controls fat mass development by altering the browning process and gut microbiota
- (2015) Lucie Geurts et al. Nature Communications
- Co-ultramicronized Palmitoylethanolamide/Luteolin in the Treatment of Cerebral Ischemia: from Rodent to Man
- (2015) Carlo Caltagirone et al. Translational Stroke Research
- Sativex in the Management of Multiple Sclerosis-Related Spasticity: Role of the Corticospinal Modulation
- (2015) Margherita Russo et al. NEURAL PLASTICITY
- Selective blockade of the hydrolysis of the endocannabinoid 2-arachidonoylglycerol impairs learning and memory performance while producing antinociceptive activity in rodents
- (2015) Guy Griebel et al. Scientific Reports
- Peroxisome Proliferator-Activated Receptorsαandγare Linked with Alcohol Consumption in Mice and Withdrawal and Dependence in Humans
- (2014) Yuri A. Blednov et al. ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH
- Treatment of Tourette Syndrome with Cannabinoids
- (2014) Kirsten R. Müller-Vahl BEHAVIOURAL NEUROLOGY
- Regulation of cannabinoid receptor gene expression and endocannabinoid levels in lymphocyte subsets by interferon-β: a longitudinal study in multiple sclerosis patients
- (2014) A. J. Sánchez López et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
- Disease-Modifying Effects of RHC80267 and JZL184 in a Pilocarpine Mouse Model of Temporal Lobe Epilepsy
- (2014) Lei Ma et al. CNS Neuroscience & Therapeutics
- Changes in Endocannabinoid Receptors and Enzymes in the Spinal Cord of SOD1G93ATransgenic Mice and Evaluation of a Sativex®-like Combination of Phytocannabinoids: Interest for Future Therapies in Amyotrophic Lateral Sclerosis
- (2014) Miguel Moreno-Martet et al. CNS Neuroscience & Therapeutics
- Targeting CB2-GPR55 Receptor Heteromers Modulates Cancer Cell Signaling
- (2014) Estefanía Moreno et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Validating Antibodies to the Cannabinoid CB2 Receptor
- (2014) Yannick Marchalant et al. JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY
- Neuroprotective Potential of Adenosine A2Aand Cannabinoid CB1Receptor Antagonists in an Animal Model of Parkinson Disease
- (2014) Silvia Cerri et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Effects of cannabidiol in the treatment of patients with Parkinson’s disease: An exploratory double-blind trial
- (2014) Marcos Hortes N Chagas et al. JOURNAL OF PSYCHOPHARMACOLOGY
- The Combination of Cannabidiol and 9-Tetrahydrocannabinol Enhances the Anticancer Effects of Radiation in an Orthotopic Murine Glioma Model
- (2014) K. A. Scott et al. MOLECULAR CANCER THERAPEUTICS
- Microglial and macrophage polarization—new prospects for brain repair
- (2014) Xiaoming Hu et al. Nature Reviews Neurology
- The monoacylglycerol lipase inhibitor JZL184 is neuroprotective and alters glial cell phenotype in the chronic MPTP mouse model
- (2014) Diana Fernández-Suárez et al. NEUROBIOLOGY OF AGING
- Involvement of central TRPV1 receptors in pentylenetetrazole and amygdala-induced kindling in male rats
- (2014) Mohsen Shirazi et al. NEUROLOGICAL SCIENCES
- ABHD6 Blockade Exerts Antiepileptic Activity in PTZ-Induced Seizures and in Spontaneous Seizures in R6/2 Mice
- (2014) Alipi V. Naydenov et al. NEURON
- Pre- and postsynaptic type-1 cannabinoid receptors control the alterations of glutamate transmission in experimental autoimmune encephalomyelitis
- (2014) Alessandra Musella et al. NEUROPHARMACOLOGY
- The fatty acid amide hydrolase inhibitor PF-3845 promotes neuronal survival, attenuates inflammation and improves functional recovery in mice with traumatic brain injury
- (2014) Flaubert Tchantchou et al. NEUROPHARMACOLOGY
- Neuroprotective Properties of Cannabigerol in Huntington’s Disease: Studies in R6/2 Mice and 3-Nitropropionate-lesioned Mice
- (2014) Sara Valdeolivas et al. Neurotherapeutics
- A restricted population of CB1 cannabinoid receptors with neuroprotective activity
- (2014) A. Chiarlone et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Pregnenolone Can Protect the Brain from Cannabis Intoxication
- (2014) Monique Vallée et al. SCIENCE
- Role of PPARγin the Differentiation and Function of Neurons
- (2014) Rodrigo A. Quintanilla et al. PPAR Research
- Amyotrophic Lateral Sclerosis Treatment with Ultramicronized Palmitoylethanolamide: A Case Report
- (2013) Simonetta Clemente CNS & Neurological Disorders-Drug Targets
- Functional Autoradiography Shows Unaltered Cannabinoid CB1 Receptor Signalling in Hippocampus and Cortex of APP/PS1 Transgenic Mice
- (2013) E. Karkkainen et al. CNS & Neurological Disorders-Drug Targets
- Effects of cannabinoids and endocannabinoid hydrolysis inhibition on pentylenetetrazole-induced seizure and electroencephalographic activity in rats
- (2013) Luciano R. Vilela et al. EPILEPSY RESEARCH
- Effects of WIN 55,212-2 mesylate on the anticonvulsant action of lamotrigine, oxcarbazepine, pregabalin and topiramate against maximal electroshock-induced seizures in mice
- (2013) Jarogniew J. Luszczki et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- In vivo type 1 cannabinoid receptor availability in Alzheimer's disease
- (2013) Rawaha Ahmad et al. EUROPEAN NEUROPSYCHOPHARMACOLOGY
- In vitroandin vivomodels of Huntington's disease show alterations in the endocannabinoid system
- (2013) Monica Bari et al. FEBS Journal
- N-arachidonoyl-L-serine (AraS) Possesses Proneurogenic Properties in Vitro and in Vivo after Traumatic Brain Injury
- (2013) Ayelet Cohen-Yeshurun et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Control of experimental spasticity by targeting the degradation of endocannabinoids using selective fatty acid amide hydrolase inhibitors
- (2013) G Pryce et al. Multiple Sclerosis Journal
- Cannabidiol provides long-lasting protection against the deleterious effects of inflammation in a viral model of multiple sclerosis: A role for A2A receptors
- (2013) M. Mecha et al. NEUROBIOLOGY OF DISEASE
- Oleoylethanolamide reduces L-DOPA-induced dyskinesia via TRPV1 receptor in a mouse model of Parkinson´s disease
- (2013) Ramiro González-Aparicio et al. NEUROBIOLOGY OF DISEASE
- Role of CB2 Cannabinoid Receptors in the Rewarding, Reinforcing and Physical Effects of Nicotine
- (2013) Francisco Navarrete et al. NEUROPSYCHOPHARMACOLOGY
- Monoacylglycerols Activate TRPV1 – A Link between Phospholipase C and TRPV1
- (2013) Peter M. Zygmunt et al. PLoS One
- Cannabinoid- and lysophosphatidylinositol-sensitive receptor GPR55 boosts neurotransmitter release at central synapses
- (2013) S. Sylantyev et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The inhibition of 2-arachidonoyl-glycerol (2-AG) biosynthesis, rather than enhancing striatal damage, protects striatal neurons from malonate-induced death: a potential role of cyclooxygenase-2-dependent metabolism of 2-AG
- (2013) S Valdeolivas et al. Cell Death & Disease
- Astroglial CB1 cannabinoid receptors regulate leptin signaling in mouse brain astrocytes
- (2013) Barbara Bosier et al. Molecular Metabolism
- Administration of palmitoylethanolamide (PEA) protects the neurovascular unit and reduces secondary injury after traumatic brain injury in mice
- (2012) Akbar Ahmad et al. BRAIN BEHAVIOR AND IMMUNITY
- Cannabidivarin is anticonvulsant in mouse and rat
- (2012) AJ Hill et al. BRITISH JOURNAL OF PHARMACOLOGY
- β−Amyloid exacerbates inflammation in astrocytes lacking fatty acid amide hydrolase through a mechanism involving PPAR-α, PPAR-γ and TRPV1, but not CB1 or CB2 receptors
- (2012) Cristina Benito et al. BRITISH JOURNAL OF PHARMACOLOGY
- Triggering of the TRPV2 channel by cannabidiol sensitizes glioblastoma cells to cytotoxic chemotherapeutic agents
- (2012) Massimo Nabissi et al. CARCINOGENESIS
- Involvement of transient receptor potential vanilloid type 1 channels in the pro-convulsant effect of anandamide in pentylenetetrazole-induced seizures
- (2012) Shyamshree S.S. Manna et al. EPILEPSY RESEARCH
- Identification and Quantification of a New Family of Peptide Endocannabinoids (Pepcans) Showing Negative Allosteric Modulation at CB1Receptors
- (2012) Mark Bauer et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Increased Expression of TRPV1 in the Cortex and Hippocampus from Patients with Mesial Temporal Lobe Epilepsy
- (2012) Fei-Ji Sun et al. JOURNAL OF MOLECULAR NEUROSCIENCE
- Mechanism of anti-glioma activity and in vivo efficacy of the cannabinoid ligand KM-233
- (2012) Steven N. Gurley et al. JOURNAL OF NEURO-ONCOLOGY
- Cannabinoid Receptor 2 Signaling in Peripheral Immune Cells Modulates Disease Onset and Severity in Mouse Models of Huntington's Disease
- (2012) J. Bouchard et al. JOURNAL OF NEUROSCIENCE
- A cannabinoid type 2 receptor agonist attenuates blood-brain barrier damage and neurodegeneration in a murine model of traumatic brain injury
- (2012) Peter S. Amenta et al. JOURNAL OF NEUROSCIENCE RESEARCH
- Selective Inhibition of Alpha/Beta-Hydrolase Domain 6 Attenuates Neurodegeneration, Alleviates Blood Brain Barrier Breakdown, and Improves Functional Recovery in a Mouse Model of Traumatic Brain Injury
- (2012) Flaubert Tchantchou et al. JOURNAL OF NEUROTRAUMA
- Neural precursor cells induce cell death of high-grade astrocytomas through stimulation of TRPV1
- (2012) Kristin Stock et al. NATURE MEDICINE
- Mitochondrial CB1 receptors regulate neuronal energy metabolism
- (2012) Giovanni Bénard et al. NATURE NEUROSCIENCE
- A CB1/CB2 receptor agonist, WIN 55,212-2, exerts its therapeutic effect in a viral autoimmune model of multiple sclerosis by restoring self-tolerance to myelin
- (2012) Angel Arevalo-Martin et al. NEUROPHARMACOLOGY
- Cannabidiol administration after hypoxia–ischemia to newborn rats reduces long-term brain injury and restores neurobehavioral function
- (2012) M.R. Pazos et al. NEUROPHARMACOLOGY
- Palmitoylethanolamide Protects Against the Amyloid-β25-35-Induced Learning and Memory Impairment in Mice, an Experimental Model of Alzheimer Disease
- (2012) Giuseppe D'Agostino et al. NEUROPSYCHOPHARMACOLOGY
- Effects of Cannabinoid Receptor Agonist WIN 55,212-2 on Blood-Brain Barrier Disruption in Focal Cerebral Ischemia in Rats
- (2012) Oak Z. Chi et al. PHARMACOLOGY
- Epigenetic Regulation of Fatty Acid Amide Hydrolase in Alzheimer Disease
- (2012) Claudio D'Addario et al. PLoS One
- Anti-inflammatory lipoxin A4 is an endogenous allosteric enhancer of CB1 cannabinoid receptor
- (2012) F. A. Pamplona et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cannabidiol exerts anti-convulsant effects in animal models of temporal lobe and partial seizures
- (2012) Nicholas A. Jones et al. SEIZURE-EUROPEAN JOURNAL OF EPILEPSY
- GPR119 as a fat sensor
- (2012) Harald S. Hansen et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- A Dysregulated Endocannabinoid-Eicosanoid Network Supports Pathogenesis in a Mouse Model of Alzheimer's Disease
- (2012) Justin R. Piro et al. Cell Reports
- Monoacylglycerol Lipase Is a Therapeutic Target for Alzheimer's Disease
- (2012) Rongqing Chen et al. Cell Reports
- Presence, formation and putative biological activities of N-acyl serotonins, a novel class of fatty-acid derived mediators, in the intestinal tract
- (2011) Kitty C.M. Verhoeckx et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Molecular reorganization of endocannabinoid signalling in Alzheimer’s disease
- (2011) Jan Mulder et al. BRAIN
- Symptom-relieving and neuroprotective effects of the phytocannabinoid Δ9-THCV in animal models of Parkinson's disease
- (2011) C García et al. BRITISH JOURNAL OF PHARMACOLOGY
- Cannabidiol inhibits pathogenic T cells, decreases spinal microglial activation and ameliorates multiple sclerosis-like disease in C57BL/6 mice
- (2011) Ewa Kozela et al. BRITISH JOURNAL OF PHARMACOLOGY
- Monoacylglycerol Lipase Exerts Dual Control over Endocannabinoid and Fatty Acid Pathways to Support Prostate Cancer
- (2011) Daniel K. Nomura et al. CHEMISTRY & BIOLOGY
- Pro-epileptic effects of the cannabinoid receptor antagonist SR141716 in a model of audiogenic epilepsy
- (2011) Lyudmila V. Vinogradova et al. EPILEPSY RESEARCH
- A randomized, double-blind, placebo-controlled, parallel-group, enriched-design study of nabiximols* (Sativex®), as add-on therapy, in subjects with refractory spasticity caused by multiple sclerosis
- (2011) A. Novotna et al. EUROPEAN JOURNAL OF NEUROLOGY
- CB2Cannabinoid Receptors Promote Neural Progenitor Cell Proliferation via mTORC1 Signaling
- (2011) Javier Palazuelos et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Alteration of endocannabinoid system in human gliomas
- (2011) Xiyue Wu et al. JOURNAL OF NEUROCHEMISTRY
- Acute Effects of a Selective Cannabinoid-2 Receptor Agonist on Neuroinflammation in a Model of Traumatic Brain Injury
- (2011) Melanie B. Elliott et al. JOURNAL OF NEUROTRAUMA
- A Combined Preclinical Therapy of Cannabinoids and Temozolomide against Glioma
- (2011) S. Torres et al. MOLECULAR CANCER THERAPEUTICS
- Cannabidiol and Other Cannabinoids Reduce Microglial Activation In Vitro and In Vivo: Relevance to Alzheimer's Disease
- (2011) A. M. Martin-Moreno et al. MOLECULAR PHARMACOLOGY
- Brain cannabinoid CB2 receptors modulate cocaine's actions in mice
- (2011) Zheng-Xiong Xi et al. NATURE NEUROSCIENCE
- Regional changes in type 1 cannabinoid receptor availability in Parkinson's disease in vivo
- (2011) Koen Van Laere et al. NEUROBIOLOGY OF AGING
- An amyloid β42-dependent deficit in anandamide mobilization is associated with cognitive dysfunction in Alzheimer's disease
- (2011) Kwang-Mook Jung et al. NEUROBIOLOGY OF AGING
- Worsening of Huntington disease phenotype in CB1 receptor knockout mice
- (2011) Stéphane Mievis et al. NEUROBIOLOGY OF DISEASE
- Cannabidiol Reduces Brain Damage and Improves Functional Recovery After Acute Hypoxia-Ischemia in Newborn Pigs
- (2011) Hector Lafuente et al. PEDIATRIC RESEARCH
- Cannabinoid Type 2 Receptor Activation Downregulates Stroke-Induced Classic and Alternative Brain Macrophage/Microglial Activation Concomitant to Neuroprotection
- (2011) Juan G. Zarruk et al. STROKE
- Effects of fatty acid amide hydrolase inhibition on neuronal responses to nicotine, cocaine and morphine in the nucleus accumbens shell and ventral tegmental area: involvement of PPAR-α nuclear receptors
- (2010) Antonio Luchicchi et al. ADDICTION BIOLOGY
- Loss of cannabinoid CB1 receptor expression in the 6-hydroxydopamine-induced nigrostriatal terminal lesion model of Parkinson's disease in the rat
- (2010) Sinéad Walsh et al. BRAIN RESEARCH BULLETIN
- Inhibition of fatty acid amide hydrolase unmasks CB1receptor and TRPV1 channel-mediated modulation of glutamatergic synaptic transmission in midbrain periaqueductal grey
- (2010) H Kawahara et al. BRITISH JOURNAL OF PHARMACOLOGY
- Possible Anandamide and Palmitoylethanolamide involvement in human stroke
- (2010) Marcello Naccarato et al. Lipids in Health and Disease
- The endocannabinoid system links gut microbiota to adipogenesis
- (2010) Giulio G Muccioli et al. Molecular Systems Biology
- Dynamic changes of anandamide in the cerebrospinal fluid of Parkinson's disease patients
- (2010) Valerio Pisani et al. MOVEMENT DISORDERS
- TRPV1 activation by endogenous anandamide triggers postsynaptic long-term depression in dentate gyrus
- (2010) Andrés E Chávez et al. NATURE NEUROSCIENCE
- Opposite changes in cannabinoid CB1 and CB2 receptor expression in human gliomas
- (2010) Maider López De Jesús et al. NEUROCHEMISTRY INTERNATIONAL
- Intact cannabinoid CB1 receptors in the Alzheimer's disease cortex
- (2010) Jasinda H. Lee et al. NEUROCHEMISTRY INTERNATIONAL
- Cannabinoid-Mediated Inhibition of Recurrent Excitatory Circuitry in the Dentate Gyrus in a Mouse Model of Temporal Lobe Epilepsy
- (2010) Muthu D. Bhaskaran et al. PLoS One
- Microglial CB2 cannabinoid receptors are neuroprotective in Huntington's disease excitotoxicity
- (2009) Javier Palazuelos et al. BRAIN
- Cannabis-based treatment induces polarity-reversing plasticity assessed by theta burst stimulation in humans
- (2009) Giacomo Koch et al. Brain Stimulation
- Involvement of nitrergic system in the anticonvulsant effect of the cannabinoid CB1 agonist ACEA in the pentylenetetrazole-induced seizure in mice
- (2009) Arash Bahremand et al. EPILEPSY RESEARCH
- Single application of a CB1 receptor antagonist rapidly following head injury prevents long-term hyperexcitability in a rat model
- (2009) Julio Echegoyen et al. EPILEPSY RESEARCH
- Cannabinoid CB2receptor agonists protect the striatum against malonate toxicity: Relevance for Huntington's disease
- (2009) Onintza Sagredo et al. GLIA
- Cannabidiol Displays Antiepileptiform and Antiseizure Properties In Vitro and In Vivo
- (2009) N. A. Jones et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Plasma endocannabinoid levels in multiple sclerosis
- (2009) L. Jean-Gilles et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
- CB2 receptor activation attenuates microcirculatory dysfunction during cerebral ischemic/reperfusion injury
- (2009) Ming Zhang et al. MICROVASCULAR RESEARCH
- A pilot study using nabilone for symptomatic treatment in Huntington's disease
- (2009) Adrienne Curtis et al. MOVEMENT DISORDERS
- An endocannabinoid tone limits excitotoxicity in vitro and in a model of multiple sclerosis
- (2009) F. Loría et al. NEUROBIOLOGY OF DISEASE
- The neuroprotective effect of cannabidiol in an in vitro model of newborn hypoxic–ischemic brain damage in mice is mediated by CB2 and adenosine receptors
- (2009) A. Castillo et al. NEUROBIOLOGY OF DISEASE
- Altered CB1 receptor and endocannabinoid levels precede motor symptom onset in a transgenic mouse model of Huntington's disease
- (2009) M.J. Dowie et al. NEUROSCIENCE
- Endocannabinoids mediate neuroprotection after transient focal cerebral ischemia
- (2008) Markus Schomacher et al. BRAIN RESEARCH
- Identification and pharmacological characterization of the prostaglandin FP receptor and FP receptor variant complexes
- (2008) Y Liang et al. BRITISH JOURNAL OF PHARMACOLOGY
- Study of the regulation of the endocannabinoid system in a virus model of multiple sclerosis reveals a therapeutic effect of palmitoylethanolamide
- (2008) Frida Loría et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Altered presymptomatic AMPA and cannabinoid receptor trafficking in motor neurons of ALS model mice: implications for excitotoxicity
- (2008) Pingwei Zhao et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Abnormalities in the cerebrospinal fluid levels of endocannabinoids in multiple sclerosis
- (2008) M Di Filippo et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- The Endocannabinoid 2-Arachidonoylglycerol Is Responsible for the Slow Self-Inhibition in Neocortical Interneurons
- (2008) S. Marinelli et al. JOURNAL OF NEUROSCIENCE
- Endocannabinoid signaling as a synaptic circuit breaker in neurological disease
- (2008) István Katona et al. NATURE MEDICINE
- Targeting the endocannabinoid system: to enhance or reduce?
- (2008) Vincenzo Di Marzo NATURE REVIEWS DRUG DISCOVERY
- Neuroprotective Effects of the Nonpsychoactive Cannabinoid Cannabidiol in Hypoxic-Ischemic Newborn Piglets
- (2008) Francisco J Alvarez et al. PEDIATRIC RESEARCH
- Biology and therapeutic potential of cannabinoid CB2receptor inverse agonists
- (2007) C A Lunn et al. BRITISH JOURNAL OF PHARMACOLOGY
- Symptom-related changes of endocannabinoid and palmitoylethanolamide levels in brain areas of R6/2 mice, a transgenic model of Huntington's disease
- (2007) Tiziana Bisogno et al. NEUROCHEMISTRY INTERNATIONAL
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