Production of riboflavin and related cofactors by biotechnological processes

Improvement of stress tolerance and riboflavin production of Bacillus subtilis by introduction of heat shock proteins from thermophilic bacillus strains

(2019) Junyang Wang et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Modular engineering of the flavin pathway in Escherichia coli for improved flavin mononucleotide and flavin adenine dinucleotide production

(2019) Shuang Liu et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Beneficial effect of a mixture of vitamin-producing and immune-modulating lactic acid bacteria as adjuvant for therapy in a recurrent mouse colitis model

(2019) Romina Levit et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Quinoa pasta fermented with lactic acid bacteria prevents nutritional deficiencies in mice

(2019) Silvana L. Carrizo et al.   FOOD RESEARCH INTERNATIONAL

Improved riboflavin production with Ashbya gossypii from vegetable oil based on 13 C metabolic network analysis with combined labeling analysis by GC/MS, LC/MS, 1D, and 2D NMR

(2018) Susanne Katharina Schwechheimer et al.   METABOLIC ENGINEERING

Integrated whole-genome and transcriptome sequence analysis reveals the genetic characteristics of a riboflavin-overproducing Bacillus subtilis

(2018) Guanglu Wang et al.   METABOLIC ENGINEERING

Protective effect of the riboflavin-overproducing strain Lactobacillus plantarum CRL2130 on intestinal mucositis in mice

(2018) Romina Levit et al.   NUTRITION

The Dimer-of-Trimers Assembly Prevents Catalysis at the Transferase Site of Prokaryotic FAD Synthase

(2018) Isaias Lans et al.   BIOPHYSICAL JOURNAL

Metabolic flux analysis in Ashbya gossypii using 13C-labeled yeast extract: industrial riboflavin production under complex nutrient conditions

(2018) Susanne Katharina Schwechheimer et al.   Microbial Cell Factories

In situ riboflavin fortification of different kefir-like cereal-based beverages using selected Andean LAB strains

(2018) Alba Yépez et al.   FOOD MICROBIOLOGY

Biofortification of riboflavin and folate in idli batter, based on fermented cereal and pulse, by Lactococcus lactis N8 and Saccharomyces boulardii SAA655

(2017) S.C. Chandrasekar Rajendran et al.   JOURNAL OF APPLIED MICROBIOLOGY

Effect of riboflavin-producing bacteria against chemically induced colitis in mice

(2017) R. Levit et al.   JOURNAL OF APPLIED MICROBIOLOGY

Evaluation of the effect of soymilk fermented by a riboflavin-producing Lactobacillus plantarum strain in a murine model of colitis

(2017) R. Levit et al.   Beneficial Microbes

The trimer interface in the quaternary structure of the bifunctional prokaryotic FAD synthetase from Corynebacterium ammoniagenes

(2017) Ana Serrano et al.   Scientific Reports

Biotechnology of riboflavin

(2016) Susanne Katharina Schwechheimer et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Increased riboflavin production by knockout of 6-phosphofructokinase I and blocking the Entner–Doudoroff pathway in Escherichia coli

(2016) Shuang Liu et al.   BIOTECHNOLOGY LETTERS

Engineering Cellular Metabolism

(2016) Jens Nielsen et al.   CELL

Overlapping riboflavin supply pathways in bacteria

(2016) Víctor Antonio García-Angulo   CRITICAL REVIEWS IN MICROBIOLOGY

Screening of Riboflavin-Producing Lactobacilli by a Polymerase-Chain-Reaction-Based Approach and Microbiological Assay

(2016) Kiran Thakur et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Invitro study of riboflavin producing lactobacilli as potential probiotic

(2016) Kiran Thakur et al.   LWT-FOOD SCIENCE AND TECHNOLOGY

Identification and characterization of the missing phosphatase on the riboflavin biosynthesis pathway inArabidopsis thaliana

(2016) Na Sa et al.   PLANT JOURNAL

Increased riboflavin production by manipulation of inosine 5′-monophosphate dehydrogenase in Ashbya gossypii

(2015) Rubén M. Buey et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Covalent Docking Predicts Substrates for Haloalkanoate Dehalogenase Superfamily Phosphatases

(2015) Nir London et al.   BIOCHEMISTRY

Quaternary organization in a bifunctional prokaryotic FAD synthetase: Involvement of an arginine at its adenylyltransferase module on the riboflavin kinase activity

(2015) Ana Serrano et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Catalysis of an Essential Step in Vitamin B2Biosynthesis by a Consortium of Broad Spectrum Hydrolases

(2015) Sonja Sarge et al.   CHEMBIOCHEM

Improvement of the riboflavin production by engineering the precursor biosynthesis pathways in Escherichia coli

(2015) Zhibo Xu et al.   CHINESE JOURNAL OF CHEMICAL ENGINEERING

Comparative metabolic flux analysis of an Ashbya gossypii wild type strain and a high riboflavin-producing mutant strain

(2015) Bo-Young Jeong et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

Structural insights into the synthesis of FMN in prokaryotic organisms

(2015) Beatriz Herguedas et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Lactic acid bacteria as a cell factory for riboflavin production

(2015) Kiran Thakur et al.   Microbial Biotechnology

Metabolic and bioprocess engineering of the yeast Candida famata for FAD production

(2014) Valentyna Y. Yatsyshyn et al.   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

Enhancement of riboflavin production by deregulating gluconeogenesis in Bacillus subtilis

(2014) Guanglu Wang et al.   WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY

The human flavoproteome

(2013) Wolf-Dieter Lienhart et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

The “Super Mutant” of Yeast FMN Adenylyltransferase Enhances the Enzyme Turnover Rate by Attenuating Product Inhibition

(2013) Carlos Huerta et al.   BIOCHEMISTRY

Detection of a quaternary organization into dimer of trimers of Corynebacterium ammoniagenes FAD synthetase at the single-molecule level and at the in cell level

(2013) Carlos Marcuello et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Enzymes from the Haloacid Dehalogenase (HAD) Superfamily Catalyse the Elusive Dephosphorylation Step of Riboflavin Biosynthesis

(2013) Ilka Haase et al.   CHEMBIOCHEM

Construction and fed-batch cultivation of Candida famata with enhanced riboflavin production

(2013) Kostyantyn Dmytruk et al.   JOURNAL OF BIOTECHNOLOGY

Enhanced riboflavin production by recombinant Bacillus subtilis RF1 through the optimization of agitation speed

(2013) Zai-wei Man et al.   WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY

Oversynthesis of Riboflavin in the Yeast Pichia guilliermondii is Accompanied by Reduced Catalase and Superoxide Dismutases Activities

(2012) Tetyana M. Prokopiv et al.   CURRENT MICROBIOLOGY

Development of fluorescent reporter tagged RIB gene cassettes for replicative transformation, early expression, and enhanced riboflavin production in Eremothecium ashbyi

(2012) Sudeshna Sengupta et al.   Fungal Biology

Flavoenzymes: Versatile catalysts in biosynthetic pathways

(2012) Christopher T. Walsh et al.   NATURAL PRODUCT REPORTS

The characterization of internal promoters in the Bacillus subtilis riboflavin biosynthesis operon

(2012) S. A. Sklyarova et al.   RUSSIAN JOURNAL OF GENETICS

The improvement of riboflavin production in Ashbya gossypii via disparity mutagenesis and DNA microarray analysis

(2011) Enoch Y. Park et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Riboflavin production by Ashbya gossypii

(2011) Tatsuya Kato et al.   BIOTECHNOLOGY LETTERS

RibM from Streptomyces davawensis is a riboflavin/roseoflavin transporter and may be useful for the optimization of riboflavin production strains

(2011) Sabrina Hemberger et al.   BMC BIOTECHNOLOGY

Flavogenomics - a genomic and structural view of flavin-dependent proteins

(2011) Peter Macheroux et al.   FEBS Journal

Improvement of Riboflavin Production byLactobacillus fermentumIsolated from Yogurt

(2011) S. Jayashree et al.   FOOD BIOTECHNOLOGY

An FMN Hydrolase of the Haloacid Dehalogenase Superfamily Is Active in Plant Chloroplasts

(2011) Renu Rawat et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genetic Control of Biosynthesis and Transport of Riboflavin and Flavin Nucleotides and Construction of Robust Biotechnological Producers

(2011) C. A. Abbas et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Cofactor Trapping, a New Method To Produce Flavin Mononucleotide

(2010) Ulrich Krauss et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Enhancement of riboflavin production with Bacillus subtilis by expression and site-directed mutagenesis of zwf and gnd gene from Corynebacterium glutamicum

(2010) Zhiwen Wang et al.   BIORESOURCE TECHNOLOGY

Evolutionary divergence of chloroplast FAD synthetase proteins

(2010) Inmaculada Yruela et al.   BMC EVOLUTIONARY BIOLOGY

Enhanced Riboflavin Production by Expressing Heterologous Riboflavin Operon from B. cereus ATCC14579 in Bacillus subtilis

(2010) Yunxia DUAN et al.   CHINESE JOURNAL OF CHEMICAL ENGINEERING

Crystal Structure of Yeast FAD Synthetase (Fad1) in Complex with FAD

(2010) Nicolas Leulliot et al.   JOURNAL OF MOLECULAR BIOLOGY

Oligomeric State in the Crystal Structure of Modular FAD Synthetase Provides Insights into Its Sequential Catalysis in Prokaryotes

(2010) Beatriz Herguedas et al.   JOURNAL OF MOLECULAR BIOLOGY

Flavin Adenine Dinucleotide Rescues the Phenotype of Frataxin Deficiency

(2010) Pilar Gonzalez-Cabo et al.   PLoS One

The microbial synthesis of flavin nucleotides: A review

(2009) V. Yu. Yatsyshyn et al.   APPLIED BIOCHEMISTRY AND MICROBIOLOGY

Overexpression of glucose-6-phosphate dehydrogenase enhances riboflavin production in Bacillus subtilis

(2009) Yun Xia Duan et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Increased production of riboflavin by metabolic engineering of the purine pathway in Bacillus subtilis

(2009) Shuobo Shi et al.   BIOCHEMICAL ENGINEERING JOURNAL

Medium optimization for production of flavin mononucleotide by the recombinant strain of the yeast Candida famata using statistical designs

(2009) Valentyna Y. Yatsyshyn et al.   BIOCHEMICAL ENGINEERING JOURNAL

Mutual Exchange of Kinetic Properties by Extended Mutagenesis in Two Short LOV Domain Proteins fromPseudomonas putida

(2009) Katrin Jentzsch et al.   BIOCHEMISTRY

Biosynthesis of riboflavin

(2009) Martin Lehmann et al.   FEBS Journal

Thapsigargin and flavin adenine dinucleotide ex vivo treatment rescues trafficking-defective gp91phox in chronic granulomatous disease leukocytes

(2009) Ya-Fang Huang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Increased riboflavin production from activated bleaching earth by a mutant strain of Ashbya gossypii

(2009) Satoshi Tajima et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

Isolation of an oxalate-resistant Ashbya gossypii strain and its improved riboflavin production

(2009) Takashi Sugimoto et al.   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

Production of flavin mononucleotide by metabolically engineered yeast Candida famata

(2009) Valentyna Y. Yatsyshyn et al.   METABOLIC ENGINEERING

Transcriptome analysis guided metabolic engineering of Bacillus subtilis for riboflavin production

(2009) Shuobo Shi et al.   METABOLIC ENGINEERING

Phosphoribosyl pyrophosphate synthetase activity affects growth and riboflavin production in Ashbya gossypii

(2008) Alberto Jiménez et al.   BMC BIOTECHNOLOGY

Structural analysis of FAD synthetase from Corynebacterium ammoniagenes

(2008) Susana Frago et al.   BMC MICROBIOLOGY

Screening of Bacillus subtilis transposon mutants with altered riboflavin production

(2008) Simon Tännler et al.   METABOLIC ENGINEERING