The double edge of anti-CD40 siRNA therapy: It increases renal microcapillar density but favours the generation of an inflammatory milieu in the kidneys of ApoE−/− mice

Synthetic Lethality: From Research to Precision Cancer Nanomedicine

(2018) Anuradha Gupta et al.   CURRENT CANCER DRUG TARGETS

OUP accepted manuscript

(2018)   Database-The Journal of Biological Databases and Curation

RNA Therapeutics in Cardiovascular Precision Medicine

(2018) Ageliki Laina et al.   Frontiers in Physiology

RNA Interference (RNAi)-Based Therapeutics: Delivering on the Promise?

(2016) Maggie L. Bobbin et al.   Annual Review of Pharmacology and Toxicology

Silencing of CD40 in vivo reduces progression of experimental atherogenesis through an NF-κB/miR-125b axis and reveals new potential mediators in the pathogenesis of atherosclerosis

(2016) Miguel Hueso et al.   ATHEROSCLEROSIS

Development and Validation of a Histological Method to Measure Microvessel Density in Whole-Slide Images of Cancer Tissue

(2016) Koen M. Marien et al.   PLoS One

Preclinical and clinical development of siRNA-based therapeutics

(2015) Gulnihal Ozcan et al.   ADVANCED DRUG DELIVERY REVIEWS

Fighting against kidney diseases with small interfering RNA: opportunities and challenges

(2015) Cheng Yang et al.   Journal of Translational Medicine

CD154-CD40 T-cell co-stimulation pathway is a key mechanism in kidney ischemia-reperfusion injury

(2015) Laura de Ramon et al.   KIDNEY INTERNATIONAL

The siRNA Non-seed Region and Its Target Sequences Are Auxiliary Determinants of Off-Target Effects

(2015) Piotr J. Kamola et al.   PLoS Computational Biology

Mechanisms of immune system activation in mammalians by small interfering RNA (siRNA)

(2015) Behzad Mansoori et al.   Artificial Cells Nanomedicine and Biotechnology

New paradigms in inflammatory signaling in vascular endothelial cells

(2013) Lei Xiao et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Delivery materials for siRNA therapeutics

(2013) Rosemary Kanasty et al.   NATURE MATERIALS

CD40 Gene Silencing Reduces the Progression of Experimental Lupus Nephritis Modulating Local Milieu and Systemic Mechanisms

(2013) Èlia Ripoll et al.   PLoS One

SeedSeq: Off-Target Transcriptome Database

(2013) Shaoli Das et al.   Biomed Research International

Naked caspase 3 small interfering RNA is effective in cold preservation but not in autotransplantation of porcine kidneys

(2012) Cheng Yang et al.   JOURNAL OF SURGICAL RESEARCH

C911: A Bench-Level Control for Sequence Specific siRNA Off-Target Effects

(2012) Eugen Buehler et al.   PLoS One

In vivo therapeutic efficacy of intra-renal CD40 silencing in a model of humoral acute rejection

(2011) E Ripoll et al.   GENE THERAPY

Modified siRNA Structure With a Single Nucleotide Bulge Overcomes Conventional siRNA-mediated Off-target Silencing

(2011) Pooja Dua et al.   MOLECULAR THERAPY

siRNA Off-Target Effects Can Be Reduced at Concentrations That Match Their Individual Potency

(2011) Daniel R. Caffrey et al.   PLoS One

Deficient CD40-TRAF6 signaling in leukocytes prevents atherosclerosis by skewing the immune response toward an antiinflammatory profile

(2010) Esther Lutgens et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Microvascular thrombosis and CD40/CD40L signaling

(2010) F. N. E. GAVINS et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Endothelial activation and circulating markers of endothelial activation in kidney disease

(2010) Ton J. Rabelink et al.   Nature Reviews Nephrology

Molecular mechanism and function of CD40/CD40L engagement in the immune system

(2009) Raul Elgueta et al.   IMMUNOLOGICAL REVIEWS

Selection of hyperfunctional siRNAs with improved potency and specificity

(2009) Xiaowei Wang et al.   NUCLEIC ACIDS RESEARCH

siRNA and Innate Immunity

(2009) Marjorie Robbins et al.   OLIGONUCLEOTIDES

Pathogenic Role of NF-κB Activation in Tubulointerstitial Inflammatory Lesions in Human Lupus Nephritis

(2008) Ling Zheng et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Apolipoprotein E knock-out and knock-in mice: atherosclerosis, metabolic syndrome, and beyond: Fig. 1.

(2008) Avani A. Pendse et al.   JOURNAL OF LIPID RESEARCH