Design and tailoring of an artificial DNA scaffolding system for efficient lycopene synthesis using zinc-finger-guided assembly

Assembly of TALE-based DNA scaffold for the enhancement of exogenous multi-enzymatic pathway

(2019) Si-si Xie et al.   JOURNAL OF BIOTECHNOLOGY

Synthetic Multienzyme Complexes, Catalytic Nanomachineries for Cascade Biosynthesis In Vivo

(2019) Jiale Qu et al.   ACS Nano

Efficient production of lycopene by engineered E. coli strains harboring different types of plasmids

(2018) Jiali Xu et al.   BIOPROCESS AND BIOSYSTEMS ENGINEERING

Enhanced production of biosynthesized lycopene via heterogenous MVA pathway based on chromosomal multiple position integration strategy plus plasmid systems in Escherichia coli

(2018) Yanlong Wei et al.   BIORESOURCE TECHNOLOGY

Can lycopene be considered an effective protection against cardiovascular disease?

(2018) J. Costa-Rodrigues et al.   FOOD CHEMISTRY

Programming Integrative Extracellular and Intracellular Biocatalysis for Rapid, Robust, and Recyclable Synthesis of Trehalose

(2018) Ling Jiang et al.   ACS Catalysis

Engineering membrane morphology and manipulating synthesis for increased lycopene accumulation in Escherichia coli cell factories

(2018) Tao Wu et al.   3 Biotech

Engineering membrane morphology and manipulating synthesis for increased lycopene accumulation in Escherichia coli cell factories

(2018) Tao Wu et al.   3 Biotech

Double-slit photoelectron interference in strong-field ionization of the neon dimer

(2018) Maksim Kunitski et al.   Nature Communications

Lipid engineering combined with systematic metabolic engineering of Saccharomyces cerevisiae for high-yield production of lycopene

(2018) Tian Ma et al.   METABOLIC ENGINEERING

Scale translation from shaken to diffused bubble aerated systems for lycopene production by Blakeslea trispora under stimulated conditions

(2016) Fani Th Mantzouridou et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

A high-throughput screening method for identifying lycopene-overproducing E. coli strain based on an antioxidant capacity assay

(2016) Xian Xu et al.   BIOCHEMICAL ENGINEERING JOURNAL

Waste cooking oil: A new substrate for carotene production by Blakeslea trispora in submerged fermentation

(2016) Konstantina Nanou et al.   BIORESOURCE TECHNOLOGY

Gene expression pattern analysis of a recombinant Escherichia coli strain possessing high growth and lycopene production capability when using fructose as carbon source

(2016) Wen Du et al.   BIOTECHNOLOGY LETTERS

Engineering Cellular Metabolism

(2016) Jens Nielsen et al.   CELL

Isopentenyl diphosphate (IPP)-bypass mevalonate pathways for isopentenol production

(2016) Aram Kang et al.   METABOLIC ENGINEERING

Lycopene overproduction in Saccharomyces cerevisiae through combining pathway engineering with host engineering

(2016) Yan Chen et al.   Microbial Cell Factories

Substrate channelling as an approach to cascade reactions

(2016) Ian Wheeldon et al.   Nature Chemistry

Lycopene: Progress in microbial production

(2016) Ayerim Hernández-Almanza et al.   TRENDS IN FOOD SCIENCE & TECHNOLOGY

Putative carotenoid genes expressed under the regulation of Shine–Dalgarno regions in Escherichia coli for efficient lycopene production

(2015) Weiyue Jin et al.   BIOTECHNOLOGY LETTERS

Lycopene and Its Antioxidant Role in the Prevention of Cardiovascular Diseases—A Critical Review

(2015) Lars Müller et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Engineering of Escherichia coli for Lycopene Production Through Promoter Engineering

(2015) Hong-Jie Shen et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Sequential control of biosynthetic pathways for balanced utilization of metabolic intermediates in Saccharomyces cerevisiae

(2015) Wenping Xie et al.   METABOLIC ENGINEERING

Targeted engineering and scale up of lycopene overproduction in Escherichia coli

(2015) Fayin Zhu et al.   PROCESS BIOCHEMISTRY

Microbial production strategies and applications of lycopene and other terpenoids

(2015) Tian Ma et al.   WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY

A novel approach for metabolic pathway optimization: Oligo-linker mediated assembly (OLMA) method

(2015) Shasha Zhang et al.   Journal of Biological Engineering

Production of lycopene by metabolically-engineered Escherichia coli

(2014) Tao Sun et al.   BIOTECHNOLOGY LETTERS

Assembly of zinc finger motif-fused enzymes on a dsDNA scaffold for catalyzing consecutive reactions with a proximity effect

(2014) Hisakage Funabashi et al.   BIOTECHNOLOGY LETTERS

Enhanced production of n-alkanes in Escherichia coli by spatial organization of biosynthetic pathway enzymes

(2014) Ziaur Rahman et al.   JOURNAL OF BIOTECHNOLOGY

Spatial modulation of key pathway enzymes by DNA-guided scaffold system and respiration chain engineering for improved N-acetylglucosamine production by Bacillus subtilis

(2014) Yanfeng Liu et al.   METABOLIC ENGINEERING

Production of Lycopene in the Non-Carotenoid-Producing Yeast Yarrowia lipolytica

(2013) Falk Matthäus et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Lycopene production in recombinant strains of Escherichia coli is improved by knockout of the central carbon metabolism gene coding for glucose-6-phosphate dehydrogenase

(2013) Yan Zhou et al.   BIOTECHNOLOGY LETTERS

Chromosomal evolution of Escherichia coli for the efficient production of lycopene

(2013) Yun-Yan Chen et al.   BMC BIOTECHNOLOGY

Mechanistic Aspects of Carotenoid Biosynthesis

(2013) Alexander R. Moise et al.   CHEMICAL REVIEWS

Improved Production of l-Threonine in Escherichia coli by Use of a DNA Scaffold System

(2012) Jun Hyoung Lee et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Substrate channeling and enzyme complexes for biotechnological applications

(2011) Y.-H. Percival Zhang   BIOTECHNOLOGY ADVANCES

DNA-guided assembly of biosynthetic pathways promotes improved catalytic efficiency

(2011) Robert J. Conrado et al.   NUCLEIC ACIDS RESEARCH

Isoprenoid Pathway Optimization for Taxol Precursor Overproduction in Escherichia coli

(2010) P. K. Ajikumar et al.   SCIENCE

Synthetic protein scaffolds provide modular control over metabolic flux

(2009) John E Dueber et al.   NATURE BIOTECHNOLOGY