标题
Intestinal microbiome and NAFLD: molecular insights and therapeutic perspectives
作者
关键词
-
出版物
JOURNAL OF GASTROENTEROLOGY
Volume 55, Issue 2, Pages 142-158
出版商
Springer Science and Business Media LLC
发表日期
2019-12-17
DOI
10.1007/s00535-019-01649-8
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Alcoholic and non-alcoholic steatohepatitis: global perspective and emerging science
- (2019) Gurmehr Brar et al. JOURNAL OF GASTROENTEROLOGY
- Randomized trial comparing effects of weight loss by liraglutide with lifestyle modification in non‐alcoholic fatty liver disease
- (2019) Joan Khoo et al. LIVER INTERNATIONAL
- Nonalcoholic fatty liver disease and the gut microbiome: Are bacteria responsible for fatty liver?
- (2019) Tien S Dong et al. EXPERIMENTAL BIOLOGY AND MEDICINE
- Fructose Promotes Leaky Gut, Endotoxemia and Liver Fibrosis through CYP 2E1‐Mediated Oxidative and Nitrative Stress
- (2019) Young‐Eun Cho et al. HEPATOLOGY
- Microbiota-driven gut vascular barrier disruption is a prerequisite for non-alcoholic steatohepatitis development
- (2019) Juliette Mouries et al. JOURNAL OF HEPATOLOGY
- The impact of short-chain fatty acids on GLP-1 and PYY secretion from the isolated perfused rat colon
- (2018) Charlotte Bayer Christiansen et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Safety, tolerability and pharmacodynamics of apical sodium-dependent bile acid transporter inhibition with volixibat in healthy adults and patients with type 2 diabetes mellitus: a randomised placebo-controlled trial
- (2018) Renger G. Tiessen et al. BMC GASTROENTEROLOGY
- Chitosan oligosaccharides improve the disturbance in glucose metabolism and reverse the dysbiosis of gut microbiota in diabetic mice
- (2018) Junping Zheng et al. CARBOHYDRATE POLYMERS
- Oral adsorbent AST-120 ameliorates gut environment and protects against the progression of renal impairment in CKD rats
- (2018) Ayumi Yoshifuji et al. Clinical and Experimental Nephrology
- Design and rationale of the INSYTE study: A randomised, placebo controlled study to test the efficacy of a synbiotic on liver fat, disease biomarkers and intestinal microbiota in non-alcoholic fatty liver disease
- (2018) Eleonora Scorletti et al. Contemporary Clinical Trials
- Histological improvement of non-alcoholic steatohepatitis with a prebiotic: a pilot clinical trial
- (2018) Marc R. Bomhof et al. EUROPEAN JOURNAL OF NUTRITION
- Intestine farnesoid X receptor agonist and the gut microbiota activate G-protein bile acid receptor-1 signaling to improve metabolism
- (2018) Preeti Pathak et al. HEPATOLOGY
- Chitin Oligosaccharide Modulates Gut Microbiota and Attenuates High-Fat-Diet-Induced Metabolic Syndrome in Mice
- (2018) Junping Zheng et al. Marine Drugs
- A randomised, double-blind, placebo-controlled phase 1 study of the safety, tolerability and pharmacodynamics of volixibat in overweight and obese but otherwise healthy adults: implications for treatment of non-alcoholic steatohepatitis
- (2018) Melissa Palmer et al. BMC Pharmacology & Toxicology
- Early differences in fecal microbiota composition in children may predict overweight
- (2018) Marko Kalliomäki et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Rifaximin in nonalcoholic fatty liver disease
- (2018) Ahmed Abdel-Razik et al. EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY
- Liraglutide modulates gut microbiota and reduces NAFLD in obese mice
- (2018) GV Moreira et al. JOURNAL OF NUTRITIONAL BIOCHEMISTRY
- Evaluation of the effect of Lactobacillus reuteri V3401 on biomarkers of inflammation, cardiovascular risk and liver steatosis in obese adults with metabolic syndrome: a randomized clinical trial (PROSIR)
- (2018) Carmen Tenorio-Jiménez et al. BMC Complementary and Alternative Medicine
- Antimicrobial proteins: intestinal guards to protect against liver disease
- (2018) Tim Hendrikx et al. JOURNAL OF GASTROENTEROLOGY
- Targeting the gut-liver axis in liver disease
- (2017) Reiner Wiest et al. JOURNAL OF HEPATOLOGY
- The FXR agonist PX20606 ameliorates portal hypertension by targeting vascular remodelling and sinusoidal dysfunction
- (2017) Philipp Schwabl et al. JOURNAL OF HEPATOLOGY
- Discovery of Tropifexor (LJN452), a Highly Potent Non-bile Acid FXR Agonist for the Treatment of Cholestatic Liver Diseases and Nonalcoholic Steatohepatitis (NASH)
- (2017) David C. Tully et al. JOURNAL OF MEDICINAL CHEMISTRY
- Bile acid–microbiota crosstalk in gastrointestinal inflammation and carcinogenesis
- (2017) Wei Jia et al. Nature Reviews Gastroenterology & Hepatology
- Expert consensus document: The International Scientific Association for Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of prebiotics
- (2017) Glenn R. Gibson et al. Nature Reviews Gastroenterology & Hepatology
- Global burden of NAFLD and NASH: trends, predictions, risk factors and prevention
- (2017) Zobair Younossi et al. Nature Reviews Gastroenterology & Hepatology
- Eubiotic properties of rifaximin: Disruption of the traditional concepts in gut microbiota modulation
- (2017) Francesca Romana Ponziani et al. WORLD JOURNAL OF GASTROENTEROLOGY
- Total fecal microbiota transplantation alleviates high-fat diet-induced steatohepatitis in mice via beneficial regulation of gut microbiota
- (2017) Da Zhou et al. Scientific Reports
- Intestinal Crosstalk between Bile Acids and Microbiota and Its Impact on Host Metabolism
- (2016) Annika Wahlström et al. Cell Metabolism
- Fungal microbiota dysbiosis in IBD
- (2016) Harry Sokol et al. GUT
- Gut microbiome and liver diseases
- (2016) Herbert Tilg et al. GUT
- Bile acids and nonalcoholic fatty liver disease: Molecular insights and therapeutic perspectives
- (2016) Juan P. Arab et al. HEPATOLOGY
- The severity of nonalcoholic fatty liver disease is associated with gut dysbiosis and shift in the metabolic function of the gut microbiota
- (2016) Jérôme Boursier et al. HEPATOLOGY
- Intestinal Dysbiosis, Barrier Dysfunction, and Bacterial Translocation Account for CKD–Related Systemic Inflammation
- (2016) Kirstin Andersen et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Liraglutide safety and efficacy in patients with non-alcoholic steatohepatitis (LEAN): a multicentre, double-blind, randomised, placebo-controlled phase 2 study
- (2016) Matthew James Armstrong et al. LANCET
- The multiple-hit pathogenesis of non-alcoholic fatty liver disease (NAFLD)
- (2016) Elena Buzzetti et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- The role of the gut microbiota in NAFLD
- (2016) Christopher Leung et al. Nature Reviews Gastroenterology & Hepatology
- The intestinal epithelial barrier: a therapeutic target?
- (2016) Matthew A. Odenwald et al. Nature Reviews Gastroenterology & Hepatology
- Inhibition of ileal bile acid uptake protects against nonalcoholic fatty liver disease in high-fat diet–fed mice
- (2016) Anuradha Rao et al. Science Translational Medicine
- Structural modulation of the gut microbiota and the relationship with body weight: compared evaluation of liraglutide and saxagliptin treatment
- (2016) Lin Wang et al. Scientific Reports
- The FXR Agonist Obeticholic Acid Prevents Gut Barrier Dysfunction and Bacterial Translocation in Cholestatic Rats
- (2015) Len Verbeke et al. AMERICAN JOURNAL OF PATHOLOGY
- Gut microbiota manipulation with prebiotics in patients with non-alcoholic fatty liver disease: a randomized controlled trial protocol
- (2015) Jennifer E. Lambert et al. BMC GASTROENTEROLOGY
- The gut microbiome in health and in disease
- (2015) Andrew B. Shreiner et al. CURRENT OPINION IN GASTROENTEROLOGY
- Efficacy of rifaximin on circulating endotoxins and cytokines in patients with nonalcoholic fatty liver disease
- (2015) Venkatanarayana Gangarapu et al. EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY
- Systematic review on intervention with prebiotics/probiotics in patients with obesity-related nonalcoholic fatty liver disease
- (2015) Giovanni Tarantino et al. Future Microbiology
- Nonalcoholic Steatohepatitis Is the Second Leading Etiology of Liver Disease Among Adults Awaiting Liver Transplantation in the United States
- (2015) Robert J. Wong et al. GASTROENTEROLOGY
- Dysbiotic gut microbiota causes transmissible Crohn's disease-like ileitis independent of failure in antimicrobial defence
- (2015) Monika Schaubeck et al. GUT
- Pharmacological inhibition of apical sodium-dependent bile acid transporter changes bile composition and blocks progression of sclerosing cholangitis in multidrug resistance 2 knockout mice
- (2015) Alexander G. Miethke et al. HEPATOLOGY
- Effects of dietary inulin on bacterial growth, short-chain fatty acid production and hepatic lipid metabolism in gnotobiotic mice
- (2015) Karolin Weitkunat et al. JOURNAL OF NUTRITIONAL BIOCHEMISTRY
- Farnesoid X nuclear receptor ligand obeticholic acid for non-cirrhotic, non-alcoholic steatohepatitis (FLINT): a multicentre, randomised, placebo-controlled trial
- (2015) Brent A Neuschwander-Tetri et al. LANCET
- A gut-vascular barrier controls the systemic dissemination of bacteria
- (2015) Ilaria Spadoni et al. SCIENCE
- Diagnosis and Assessment of NAFLD: Definitions and Histopathological Classification
- (2015) Carolin Lackner et al. SEMINARS IN LIVER DISEASE
- The human gut sterolbiome: bile acid-microbiome endocrine aspects and therapeutics
- (2015) Jason M. Ridlon et al. Acta Pharmaceutica Sinica B
- Randomised clinical trial: the beneficial effects of VSL#3 in obese children with non-alcoholic steatohepatitis
- (2014) A. Alisi et al. ALIMENTARY PHARMACOLOGY & THERAPEUTICS
- Synbiotic supplementation in nonalcoholic fatty liver disease: a randomized, double-blind, placebo-controlled pilot study
- (2014) Tannaz Eslamparast et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Interactions Between the Intestinal Microbiome and Liver Diseases
- (2014) Bernd Schnabl et al. GASTROENTEROLOGY
- Pilot study of liraglutide effects in non-alcoholic steatohepatitis and non-alcoholic fatty liver disease with glucose intolerance in Japanese patients (LEAN-J)
- (2014) Yuichiro Eguchi et al. HEPATOLOGY RESEARCH
- Intestinal transport and metabolism of bile acids
- (2014) Paul A. Dawson et al. JOURNAL OF LIPID RESEARCH
- FXR agonist GW4064 alleviates endotoxin-induced hepatic inflammation by repressing macrophage activation
- (2014) Jun Yao WORLD JOURNAL OF GASTROENTEROLOGY
- Gut-liver axis and probiotics: Their role in non-alcoholic fatty liver disease
- (2014) Giulia Paolella WORLD JOURNAL OF GASTROENTEROLOGY
- Microbial Modulation of Energy Availability in the Colon Regulates Intestinal Transit
- (2013) Anita Wichmann et al. Cell Host & Microbe
- Glucagon-like peptide-1 analogue, liraglutide, improves liver fibrosis markers in obese women with polycystic ovary syndrome and nonalcoholic fatty liver disease
- (2013) H. Kahal et al. CLINICAL ENDOCRINOLOGY
- Gut microbiota, enteroendocrine functions and metabolism
- (2013) Patrice D Cani et al. CURRENT OPINION IN PHARMACOLOGY
- Benefits of Liraglutide Treatment in Overweight and Obese Older Individuals With Prediabetes
- (2013) S. H. Kim et al. DIABETES CARE
- Clostridium Butyricum MIYAIRI 588 Improves High-Fat Diet-Induced Non-Alcoholic Fatty Liver Disease in Rats
- (2013) Makoto Seo et al. DIGESTIVE DISEASES AND SCIENCES
- Efficacy and Safety of the Farnesoid X Receptor Agonist Obeticholic Acid in Patients With Type 2 Diabetes and Nonalcoholic Fatty Liver Disease
- (2013) Sunder Mudaliar et al. GASTROENTEROLOGY
- Increased De Novo Lipogenesis Is a Distinct Characteristic of Individuals With Nonalcoholic Fatty Liver Disease
- (2013) Jennifer E. Lambert et al. GASTROENTEROLOGY
- Yin Yang 1 promotes hepatic steatosis through repression of farnesoid X receptor in obese mice
- (2013) Yan Lu et al. GUT
- Side effects of antibiotics during bacterial infection: Mitochondria, the main target in host cell
- (2013) Rochika Singh et al. MITOCHONDRION
- Synthetic FXR Agonist GW4064 Prevents Diet-Induced Hepatic Steatosis and Insulin Resistance
- (2013) Yongjie Ma et al. PHARMACEUTICAL RESEARCH
- Butyrate-Producing Probiotics Reduce Nonalcoholic Fatty Liver Disease Progression in Rats: New Insight into the Probiotics for the Gut-Liver Axis
- (2013) Hitoshi Endo et al. PLoS One
- Farnesoid X receptor targeting to treat nonalcoholic steatohepatitis
- (2012) Luciano Adorini et al. DRUG DISCOVERY TODAY
- PMO-128 Effects of oral nanoporous carbon therapy in leptin null mice as a model of non-alcoholic steatohepatitis
- (2012) J Macnaughtan et al. GUT
- Insight into the prebiotic concept: lessons from an exploratory, double blind intervention study with inulin-type fructans in obese women
- (2012) Evelyne M Dewulf et al. GUT
- Intestinal microbiota determines development of non-alcoholic fatty liver disease in mice
- (2012) Tiphaine Le Roy et al. GUT
- Effect of colesevelam on liver fat quantified by magnetic resonance in nonalcoholic steatohepatitis: A randomized controlled trial
- (2012) Thuy-Anh Le et al. HEPATOLOGY
- Characterization of gut microbiomes in nonalcoholic steatohepatitis (NASH) patients: A connection between endogenous alcohol and NASH
- (2012) Lixin Zhu et al. HEPATOLOGY
- The interpersonal and intrapersonal diversity of human-associated microbiota in key body sites
- (2012) Luke K. Ursell et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Prebiotic approach alleviates hepatic steatosis: Implication of fatty acid oxidative and cholesterol synthesis pathways
- (2012) Barbara D. Pachikian et al. MOLECULAR NUTRITION & FOOD RESEARCH
- Functional interactions between the gut microbiota and host metabolism
- (2012) Valentina Tremaroli et al. NATURE
- Bifidobacterium longum supplementation improved high-fat-fed-induced metabolic syndrome and promoted intestinal Reg I gene expression
- (2011) Jin Jin Chen et al. EXPERIMENTAL BIOLOGY AND MEDICINE
- Bile Acid Is a Host Factor That Regulates the Composition of the Cecal Microbiota in Rats
- (2011) K.B.M. Saiful Islam et al. GASTROENTEROLOGY
- AST-120 (spherical carbon adsorbent) lowers ammonia levels and attenuates brain edema in bile duct-ligated rats
- (2011) Cristina R. Bosoi et al. HEPATOLOGY
- Probiotics as an emerging therapeutic strategy to treat NAFLD: focus on molecular and biochemical mechanisms
- (2011) Anna Iacono et al. JOURNAL OF NUTRITIONAL BIOCHEMISTRY
- The potential role of prebiotic fibre for treatment and management of non-alcoholic fatty liver disease and associated obesity and insulin resistance
- (2011) Jill A. Parnell et al. LIVER INTERNATIONAL
- Uremic Toxins and Oral Adsorbents
- (2011) Shunsuke Goto et al. THERAPEUTIC APHERESIS AND DIALYSIS
- Efficacy and safety of the probiotic Saccharomyces boulardii for the prevention and therapy of gastrointestinal disorders
- (2011) Theodoros Kelesidis et al. Therapeutic Advances in Gastroenterology
- Regulation of human epithelial tight junction proteins by Lactobacillus plantarum in vivo and protective effects on the epithelial barrier
- (2010) Jurgen Karczewski et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Interaction of probiotics and pathogens—benefits to human health?
- (2010) Seppo Salminen et al. CURRENT OPINION IN BIOTECHNOLOGY
- High-dose ursodeoxycholic acid therapy for nonalcoholic steatohepatitis: a double-blind, randomized, placebo-controlled trial
- (2010) Ulrich F. H. Leuschner et al. HEPATOLOGY
- Effects of nuclear receptor FXR on the regulation of liver lipid metabolism in patients with non-alcoholic fatty liver disease
- (2010) Zhao-Xia Yang et al. Hepatology International
- Elevated endotoxin levels in non-alcoholic fatty liver disease
- (2010) Alison L Harte et al. Journal of Inflammation-London
- Rifaximin Treatment in Hepatic Encephalopathy
- (2010) Nathan M. Bass et al. NEW ENGLAND JOURNAL OF MEDICINE
- Increased intestinal permeability and tight junction alterations in nonalcoholic fatty liver disease
- (2009) Luca Miele et al. HEPATOLOGY
- Treatment of nonalcoholic steatohepatitis with colestimide
- (2009) Makiko Taniai et al. HEPATOLOGY RESEARCH
- Farnesoid X receptor agonist WAY-362450 attenuates liver inflammation and fibrosis in murine model of non-alcoholic steatohepatitis
- (2009) Songwen Zhang et al. JOURNAL OF HEPATOLOGY
- FXR activation reverses insulin resistance and lipid abnormalities and protects against liver steatosis in Zucker (fa/fa) obese rats
- (2009) Sabrina Cipriani et al. JOURNAL OF LIPID RESEARCH
- Bile acids: regulation of synthesis
- (2009) John Y. L. Chiang JOURNAL OF LIPID RESEARCH
- Discovery of XL335 (WAY-362450), a Highly Potent, Selective, and Orally Active Agonist of the Farnesoid X Receptor (FXR)
- (2009) Brenton Flatt et al. JOURNAL OF MEDICINAL CHEMISTRY
- Colesevelam HCl effects on atherogenic lipoprotein subclasses in subjects with type 2 diabetes
- (2008) Robert S. Rosenson et al. ATHEROSCLEROSIS
- Bile Salts Control the Antimicrobial Peptide Cathelicidin Through Nuclear Receptors in the Human Biliary Epithelium
- (2008) Emilie D'Aldebert et al. GASTROENTEROLOGY
- Antibiotics protect against fructose-induced hepatic lipid accumulation in mice: Role of endotoxin
- (2008) Ina Bergheim et al. JOURNAL OF HEPATOLOGY
- Genes and Molecules of Lactobacilli Supporting Probiotic Action
- (2008) S. Lebeer et al. MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS
- Targeting bile-acid signalling for metabolic diseases
- (2008) Charles Thomas et al. NATURE REVIEWS DRUG DISCOVERY
- Small intestinal bacteria overgrowth decreases small intestinal motility in the NASH rats
- (2008) Wan-Chun Wu et al. WORLD JOURNAL OF GASTROENTEROLOGY
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