Amylin structure-function relationships and receptor pharmacology: implications for amylin mimetic drug development
出版年份 2016 全文链接
标题
Amylin structure-function relationships and receptor pharmacology: implications for amylin mimetic drug development
作者
关键词
-
出版物
BRITISH JOURNAL OF PHARMACOLOGY
Volume 173, Issue 12, Pages 1883-1898
出版商
Wiley
发表日期
2016-04-11
DOI
10.1111/bph.13496
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Receptor Activity-Modifying Proteins (RAMPs): New Insights and Roles
- (2016) Debbie L. Hay et al. Annual Review of Pharmacology and Toxicology
- Calcitonin and Amylin Receptor Peptide Interaction Mechanisms
- (2016) Sang-Min Lee et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Effect of Pramlintide on Postprandial Glucose Fluxes in Type 1 Diabetes
- (2016) Ling Hinshaw et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Islet Amyloid Polypeptide: Structure, Function, and Pathophysiology
- (2016) Rehana Akter et al. Journal of Diabetes Research
- The Concise Guide to PHARMACOLOGY 2015/16: G protein-coupled receptors
- (2015) Stephen PH Alexander et al. BRITISH JOURNAL OF PHARMACOLOGY
- Aspects of structural landscape of human islet amyloid polypeptide
- (2015) Jianfeng He et al. JOURNAL OF CHEMICAL PHYSICS
- Short Hydrophobic Peptides with Cyclic Constraints Are Potent Glucagon-like Peptide-1 Receptor (GLP-1R) Agonists
- (2015) Huy N. Hoang et al. JOURNAL OF MEDICINAL CHEMISTRY
- Structural Basis for Receptor Activity-Modifying Protein-Dependent Selective Peptide Recognition by a G Protein-Coupled Receptor
- (2015) Jason M. Booe et al. MOLECULAR CELL
- The role of copper(II) and zinc(II) in the degradation of human and murine IAPP by insulin-degrading enzyme
- (2014) Francesco Bellia et al. JOURNAL OF MASS SPECTROMETRY
- Anti-diabetic activity of insulin-degrading enzyme inhibitors mediated by multiple hormones
- (2014) Juan Pablo Maianti et al. NATURE
- Convergent chemoenzymatic synthesis of a library of glycosylated analogues of pramlintide: structure–activity relationships for amylin receptor agonism
- (2014) Renata Kowalczyk et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Preparation and Characterization of PEGylated Amylin
- (2013) Luiz Henrique Guerreiro et al. AAPS PHARMSCITECH
- Selectively N-Methylated Soluble IAPP Mimics as Potent IAPP Receptor Agonists and Nanomolar Inhibitors of Cytotoxic Self-Assembly of Both IAPP and Aβ40
- (2013) Li-Mei Yan et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Effect of Proline Mutations on the Monomer Conformations of Amylin
- (2013) Chi-cheng Chiu et al. BIOPHYSICAL JOURNAL
- Structure-activity relationships of the N-terminus of calcitonin gene-related peptide: key roles of alanine-5 and threonine-6 in receptor activation
- (2013) Debbie L Hay et al. BRITISH JOURNAL OF PHARMACOLOGY
- Glycosylation of Pramlintide: Synthetic Glycopeptides that Display In Vitro and In Vivo Activities as Amylin Receptor Agonists
- (2013) Yusuke Tomabechi et al. CHEMISTRY-A EUROPEAN JOURNAL
- Activity of Pramlintide, Rat and Human Amylin but not Aβ1–42at Human Amylin Receptors
- (2013) Joseph J. Gingell et al. ENDOCRINOLOGY
- Bifunctional PEGylated Exenatide-Amylinomimetic Hybrids to Treat Metabolic Disorders: An Example of Long-Acting Dual Hormonal Therapeutics
- (2013) Chengzao Sun et al. JOURNAL OF MEDICINAL CHEMISTRY
- The IUPHAR/BPS Guide to PHARMACOLOGY: an expert-driven knowledgebase of drug targets and their ligands
- (2013) Adam J. Pawson et al. NUCLEIC ACIDS RESEARCH
- Improved Glucose Control and Reduced Body Weight in Rodents with Dual Mechanism of Action Peptide Hybrids
- (2013) James L. Trevaskis et al. PLoS One
- Amylin Conjugation with Methoxyl Polyethyleneglycol
- (2013) Mariana F. A. N. Guterres et al. PROTEIN AND PEPTIDE LETTERS
- Selective CGRP and adrenomedullin peptide binding by tethered RAMP-calcitonin receptor-like receptor extracellular domain fusion proteins
- (2013) Heather E. Moad et al. PROTEIN SCIENCE
- Structural Similarities and Differences between Amyloidogenic and Non-Amyloidogenic Islet Amyloid Polypeptide (IAPP) Sequences and Implications for the Dual Physiological and Pathological Activities of These Peptides
- (2013) Chun Wu et al. PLoS Computational Biology
- Synthesis and evaluation of disulfide bond mimetics of amylin-(1–8) as agents to treat osteoporosis
- (2012) Renata Kowalczyk et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Receptor activity-modifying protein-dependent impairment of calcitonin receptor splice variant Δ(1-47)hCT(a)function
- (2012) T Qi et al. BRITISH JOURNAL OF PHARMACOLOGY
- Structure-activity relationships for α-calcitonin gene-related peptide
- (2012) Harriet A Watkins et al. BRITISH JOURNAL OF PHARMACOLOGY
- The structure of secretin family GPCR peptide ligands: implications for receptor pharmacology and drug development
- (2012) Harriet A. Watkins et al. DRUG DISCOVERY TODAY
- Calcitonin and calcitonin receptor-like receptors: common themes with family B GPCRs?
- (2011) James Barwell et al. BRITISH JOURNAL OF PHARMACOLOGY
- Pharmacological characterization of rat amylin receptors: implications for the identification of amylin receptor subtypes
- (2011) RJ Bailey et al. BRITISH JOURNAL OF PHARMACOLOGY
- Glucoregulatory effects and prolonged duration of action of davalintide: a novel amylinomimetic peptide
- (2011) C. M. Mack et al. DIABETES OBESITY & METABOLISM
- Delivery of Therapeutic Proteins
- (2010) Dipak S. Pisal et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Davalintide (AC2307), a novel amylin-mimetic peptide: enhanced pharmacological properties over native amylin to reduce food intake and body weight
- (2009) C M Mack et al. INTERNATIONAL JOURNAL OF OBESITY
- Eleven Amino Acid Glucagon-like Peptide-1 Receptor Agonists with Antidiabetic Activity
- (2009) Claudio Mapelli et al. JOURNAL OF MEDICINAL CHEMISTRY
- Molecular Basis for the Recognition and Cleavages of IGF-II, TGF-α, and Amylin by Human Insulin-Degrading Enzyme
- (2009) Qing Guo et al. JOURNAL OF MOLECULAR BIOLOGY
- Three-Dimensional Structure and Orientation of Rat Islet Amyloid Polypeptide Protein in a Membrane Environment by Solution NMR Spectroscopy
- (2009) Ravi Prakash Reddy Nanga et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Structures of Rat and Human Islet Amyloid Polypeptide IAPP1−19in Micelles by NMR Spectroscopy†
- (2008) Ravi Prakash Reddy Nanga et al. BIOCHEMISTRY
- Receptor Activity-Modifying Proteins Differentially Modulate the G Protein-Coupling Efficiency of Amylin Receptors
- (2008) Maria Morfis et al. ENDOCRINOLOGY
- A Biophysical Characterization of the Peptide Drug Pramlintide (AC137) Using Empirical Phase Diagrams
- (2007) Akihisa Nonoyama et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- The effects of C-terminal truncation of receptor activity modifying proteins on the induction of amylin receptor phenotype from human CTb receptors
- (2007) Madhara Udawela et al. REGULATORY PEPTIDES
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started