Structure-activity relationships for α-calcitonin gene-related peptide

The role of the extracellular loops of the CGRP receptor, a family B GPCR

(2012) James Barwell et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Receptor activity-modifying protein-dependent impairment of calcitonin receptor splice variant Δ(1-47)hCT(a)function

(2012) T Qi et al.   BRITISH JOURNAL OF PHARMACOLOGY

The structure of secretin family GPCR peptide ligands: implications for receptor pharmacology and drug development

(2012) Harriet A. Watkins et al.   DRUG DISCOVERY TODAY

CGRP receptor antagonists: an expanding drug class for acute migraine?

(2012) Andrea Negro et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Structure and membrane orientation of IAPP in its natively amidated form at physiological pH in a membrane environment

(2011) Ravi Prakash Reddy Nanga et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Structure of micelle-bound adrenomedullin: A first step toward the analysis of its interactions with receptors and small molecules

(2011) Javier Pérez-Castells et al.   BIOPOLYMERS

VPAC receptors: structure, molecular pharmacology and interaction with accessory proteins

(2011) Alain Couvineau et al.   BRITISH JOURNAL OF PHARMACOLOGY

Calcitonin and calcitonin receptor-like receptors: common themes with family B GPCRs?

(2011) James Barwell et al.   BRITISH JOURNAL OF PHARMACOLOGY

Novel GLP-1 receptor agonists for diabetes

(2011) Alan J Garber   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Discovery of potent, cyclic calcitonin gene-related peptide receptor antagonists

(2011) Liang Zeng Yan et al.   JOURNAL OF PEPTIDE SCIENCE

Biomimetic Screening of Class-B G Protein-Coupled Receptors

(2011) Christian Devigny et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Shared and separate functions of the RAMP-based adrenomedullin receptors

(2011) Kenji Kuwasako et al.   PEPTIDES

Structural insights into RAMP modification of secretin family G protein-coupled receptors: implications for drug development

(2011) Julia K. Archbold et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Mapping the CGRP receptor ligand binding domain: Tryptophan-84 of RAMP1 is critical for agonist and antagonist binding

(2010) E.L. Moore et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Calcitonin Gene-Related Peptide (CGRP) Receptor Antagonists in the Treatment of Migraine

(2010) Paul L. Durham et al.   CNS DRUGS

Crystal Structure of the Ectodomain Complex of the CGRP Receptor, a Class-B GPCR, Reveals the Site of Drug Antagonism

(2010) Ernst ter Haar et al.   STRUCTURE

Dynamic α-Helix Structure of Micelle-bound Human Amylin

(2009) Sharadrao M. Patil et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Basis for Parathyroid Hormone-related Protein Binding to the Parathyroid Hormone Receptor and Design of Conformation-selective Peptides

(2009) Augen A. Pioszak et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal Structure of Glucagon-like Peptide-1 in Complex with the Extracellular Domain of the Glucagon-like Peptide-1 Receptor

(2009) Christina Rye Underwood et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Novel Peptide Antagonists of Adrenomedullin and Calcitonin Gene-Related Peptide Receptors: Identification, Pharmacological Characterization, and Interactions with Position 74 in Receptor Activity-Modifying Protein 1/3

(2009) S. D. Robinson et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Mapping interaction sites within the N-terminus of the calcitonin gene-related peptide receptor; the role of residues 23–60 of the calcitonin receptor-like receptor

(2009) James Barwell et al.   PEPTIDES

Functional characterization of two human receptor activity-modifying protein 3 variants

(2009) Richard J. Bailey et al.   PEPTIDES

Passing the baton in class B GPCRs: peptide hormone activation via helix induction?

(2009) Christoph Parthier et al.   TRENDS IN BIOCHEMICAL SCIENCES

Crystal Structure of the Ligand-bound Glucagon-like Peptide-1 Receptor Extracellular Domain

(2008) Steffen Runge et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of Potent, Selective, and Metabolically Stable Peptide Antagonists to the Calcitonin Gene-Related Peptide (CGRP) Receptor

(2008) Les P. Miranda et al.   JOURNAL OF MEDICINAL CHEMISTRY

Pharmacologic study of C-terminal fragments of frog skin calcitonin gene-related peptide

(2008) Ali Ladram et al.   PEPTIDES

International Union of Pharmacology. LXIX. Status of the Calcitonin Gene-Related Peptide Subtype 2 Receptor

(2008) D. L. Hay et al.   PHARMACOLOGICAL REVIEWS

Molecular recognition of parathyroid hormone by its G protein-coupled receptor

(2008) Augen A. Pioszak et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Class-B GPCR activation: is ligand helix-capping the key?

(2008) Jean-Michel Neumann et al.   TRENDS IN BIOCHEMICAL SCIENCES