Eact, a small molecule activator of TMEM16A, activates TRPV1 and elicits pain- and itch-related behaviours

The Concise Guide to PHARMACOLOGY 2015/16: Other ion channels

(2015) Stephen PH Alexander et al.   BRITISH JOURNAL OF PHARMACOLOGY

9-Phenanthrol inhibits recombinant and arterial myocyte TMEM16A channels

(2015) Sarah K Burris et al.   BRITISH JOURNAL OF PHARMACOLOGY

The Concise Guide to PHARMACOLOGY 2015/16: Voltage-gated ion channels

(2015) Stephen PH Alexander et al.   BRITISH JOURNAL OF PHARMACOLOGY

The Concise Guide to PHARMACOLOGY 2015/16: Enzymes

(2015) Stephen PH Alexander et al.   BRITISH JOURNAL OF PHARMACOLOGY

Experimental design and analysis and their reporting: new guidance for publication in BJP

(2015) Michael J Curtis et al.   BRITISH JOURNAL OF PHARMACOLOGY

Implementing guidelines on reporting research using animals (ARRIVE etc.): new requirements for publication in BJP

(2015) John C McGrath et al.   BRITISH JOURNAL OF PHARMACOLOGY

Molecular and cellular mechanisms that initiate pain and itch

(2015) Jialie Luo et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Anoctamin-1 Cl− Channels in Nociception: Activation by an N-Aroylaminothiazole and Capsaicin and Inhibition by T16A[inh]-A01

(2015) Farah Deba et al.   Molecular Pain

Role of Anoctamin-1 and Bestrophin-1 in Spinal Nerve Ligation-Induced Neuropathic Pain in Rats

(2015) Jorge Baruch Pineda-Farias et al.   Molecular Pain

Etiology of distinct membrane excitability in pre- and posthearing auditory neurons relies on activity of Cl−channel TMEM16A

(2015) Xiao-Dong Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pain-enhancing mechanism through interaction between TRPV1 and anoctamin 1 in sensory neurons

(2015) Yasunori Takayama et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Secreted CLCA1 modulates TMEM16A to activate Ca2+-dependent chloride currents in human cells

(2015) Monica Sala-Rabanal et al.   eLife

Expression of transient receptor potential vanilloid 1 and anoctamin 1 in rat trigeminal ganglion neurons innervating the tongue

(2014) Takuya Kanazawa et al.   BRAIN RESEARCH BULLETIN

Anoctamin 1 Calcium-Activated Chloride Channel Downregulates Estrogen Production in Mouse Ovarian Granulosa Cells

(2014) Meiyan Sun et al.   ENDOCRINOLOGY

Modulation of water efflux through functional interaction between TRPV4 and TMEM16A/anoctamin 1

(2014) Yasunori Takayama et al.   FASEB JOURNAL

Ano1, a Ca2+-activated Cl−channel, coordinates contractility in mouse intestine by Ca2+transient coordination between interstitial cells of Cajal

(2014) Raman Deep Singh et al.   JOURNAL OF PHYSIOLOGY-LONDON

Anoctamin 1 Contributes to Inflammatory and Nerve-Injury Induced Hypersensitivity

(2014) Byeongjun Lee et al.   Molecular Pain

LE135, a retinoid acid receptor antagonist, produces pain through direct activation of TRP channels

(2013) Shijin Yin et al.   BRITISH JOURNAL OF PHARMACOLOGY

Retinoids activate the irritant receptor TRPV1 and produce sensory hypersensitivity

(2013) Shijin Yin et al.   JOURNAL OF CLINICAL INVESTIGATION

Distinctive Changes in Plasma Membrane Phosphoinositides Underlie Differential Regulation of TRPV1 in Nociceptive Neurons

(2013) V. Lukacs et al.   JOURNAL OF NEUROSCIENCE

The IUPHAR/BPS Guide to PHARMACOLOGY: an expert-driven knowledgebase of drug targets and their ligands

(2013) Adam J. Pawson et al.   NUCLEIC ACIDS RESEARCH

Activation of the Cl- Channel ANO1 by Localized Calcium Signals in Nociceptive Sensory Neurons Requires Coupling with the IP3 Receptor

(2013) X. Jin et al.   Science Signaling

Potent vasorelaxant activity of the TMEM16A inhibitor T16Ainh-A01

(2012) Alison J Davis et al.   BRITISH JOURNAL OF PHARMACOLOGY

Epidermal growth factor chronically upregulates Ca2+-dependent Cl−conductance and TMEM16A expression in intestinal epithelial cells

(2012) Magdalena S. Mroz et al.   JOURNAL OF PHYSIOLOGY-LONDON

The calcium-activated chloride channel anoctamin 1 acts as a heat sensor in nociceptive neurons

(2012) Hawon Cho et al.   NATURE NEUROSCIENCE

Potassium and ANO1/ TMEM16A chloride channel profiles distinguish atypical and typical smooth muscle cells from interstitial cells in the mouse renal pelvis

(2011) Javed Iqbal et al.   BRITISH JOURNAL OF PHARMACOLOGY

The biophysical and molecular basis of TRPV1 proton gating

(2011) Eduardo Aneiros et al.   EMBO JOURNAL

Small-molecule activators of TMEM16A, a calcium-activated chloride channel, stimulate epithelial chloride secretion and intestinal contraction

(2011) Wan Namkung et al.   FASEB JOURNAL

Animal research: Reporting in vivo experiments: The ARRIVE guidelines

(2010) Carol Kilkenny et al.   BRITISH JOURNAL OF PHARMACOLOGY

The acute nociceptive signals induced by bradykinin in rat sensory neurons are mediated by inhibition of M-type K+ channels and activation of Ca2+-activated Cl– channels

(2010) Boyi Liu et al.   JOURNAL OF CLINICAL INVESTIGATION

Cellular and Molecular Mechanisms of Pain

(2009) Allan I. Basbaum et al.   CELL

Activation of TRPV1 and TRPA1 leads to muscle nociception and mechanical hyperalgesia

(2009) Jin Y. Ro et al.   PAIN

TRPV1-expressing primary afferents generate behavioral responses to pruritogens via multiple mechanisms

(2009) N. Imamachi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Studies on expression and function of the TMEM16A calcium-activated chloride channel

(2009) Fen Huang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cellular Basis of Itch Sensation

(2009) Y.-G. Sun et al.   SCIENCE

Expression Cloning of TMEM16A as a Calcium-Activated Chloride Channel Subunit

(2008) Björn Christian Schroeder et al.   CELL

TMEM16A confers receptor-activated calcium-dependent chloride conductance

(2008) Young Duk Yang et al.   NATURE