Absence of VEGFR‐1/Flt‐1 signaling pathway in mice results in insensitivity to discogenic low back pain in an established disc injury mouse model

Development of an in vivo mouse model of discogenic low back pain

(2018) Changgui Shi et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Animal models for studying the etiology and treatment of low back pain

(2018) Changgui Shi et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Vascular Endothelial Growth Factor in Cartilage Development and Osteoarthritis

(2017) Masashi Nagao et al.   Scientific Reports

PKCδnull mutations in a mouse model of osteoarthritis alter osteoarthritic pain independently of joint pathology by augmenting NGF/TrkA-induced axonal outgrowth

(2016) Ranjan Kc et al.   ANNALS OF THE RHEUMATIC DISEASES

Targeting VEGF and Its Receptors for the Treatment of Osteoarthritis and Associated Pain

(2016) John L Hamilton et al.   JOURNAL OF BONE AND MINERAL RESEARCH

MicroRNA-146a reduces IL-1 dependent inflammatory responses in the intervertebral disc

(2015) Su-Xi Gu et al.   GENE

Exploratory study for identifying systemic biomarkers that correlate with pain response in patients with intervertebral disc disorders

(2015) K. T. Weber et al.   IMMUNOLOGIC RESEARCH

Bevacizumab, an anti-vascular endothelial growth factor antibody, inhibits osteoarthritis

(2014) Toshihiro Nagai et al.   ARTHRITIS RESEARCH & THERAPY

Relationship between neovascularization and degenerative changes in herniated lumbar intervertebral discs

(2013) Tõnu Rätsep et al.   EUROPEAN SPINE JOURNAL

Lactoferricin enhances BMP7-stimulated anabolic pathways in intervertebral disc cells

(2013) Michael B. Ellman et al.   GENE

Lactoferricin mediates anti-inflammatory and anti-catabolic effects via inhibition of IL-1 and LPS activity in the intervertebral disc

(2013) Jae-Sung Kim et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Glia and pain: Is chronic pain a gliopathy?

(2013) Ru-Rong Ji et al.   PAIN

Clinical diagnosis for discogenic low back pain

(2012) Yin-gang Zhang et al.   International Journal of Biological Sciences

Injection of vascular endothelial growth factor into knee joints induces osteoarthritis in mice

(2012) A. Ludin et al.   OSTEOARTHRITIS AND CARTILAGE

Lactoferricin mediates anabolic and anti-catabolic effects in the intervertebral disc

(2011) Jae-Sung Kim et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Degenerative Magnetic Resonance Imaging Changes in Patients With Chronic Low Back Pain

(2011) Dean Chou et al.   SPINE

Insulin-like growth factor 1 synergizes with bone morphogenetic protein 7-mediated anabolism in bovine intervertebral disc cells

(2010) Jae-Sung Kim et al.   ARTHRITIS AND RHEUMATISM

Alteration of sensory neurons and spinal response to an experimental osteoarthritis pain model

(2010) Hee-Jeong Im et al.   ARTHRITIS AND RHEUMATISM

VEGF and its receptor-2 involved in neuropathic pain transmission mediated by P2X2/3 receptor of primary sensory neurons

(2010) Jiari Lin et al.   BRAIN RESEARCH BULLETIN

Targeting astrocyte signaling for chronic pain

(2010) Yong-Jing Gao et al.   Neurotherapeutics

Frequency of Lumbar Intervertebral Disc Calcification and Angiogenesis, and Their Correlation With Clinical, Surgical, and Magnetic Resonance Imaging Findings

(2010) Saeid Karamouzian et al.   SPINE

VEGFR1 Activity Modulates Myeloid Cell Infiltration in Growing Lung Metastases but Is Not Required for Spontaneous Metastasis Formation

(2009) Michelle R. Dawson et al.   PLoS One

Pathological and protective roles of glia in chronic pain

(2008) Erin D. Milligan et al.   NATURE REVIEWS NEUROSCIENCE

A systematic review of low back pain cost of illness studies in the United States and internationally

(2008) Simon Dagenais et al.   Spine Journal

Action of fibroblast growth factor-2 on the intervertebral disc

(2008) Xin Li et al.   ARTHRITIS RESEARCH & THERAPY