Effect of APOE Genotype on Plasma Docosahexaenoic Acid (DHA), Eicosapentaenoic Acid, Arachidonic Acid, and Hippocampal Volume in the Alzheimer’s Disease Cooperative Study-Sponsored DHA Clinical Trial

The eicosapentaenoic acid:arachidonic acid ratio and its clinical utility in cardiovascular disease

(2019) J. R. Nelson et al.   POSTGRADUATE MEDICINE

Altered SPMs and age-associated decrease in brain DHA in APOE4 female mice

(2019) Anneloes Martinsen et al.   FASEB JOURNAL

The impact of APOE genotype on survival: Results of 38,537 participants from six population-based cohorts (E2-CHARGE)

(2019) Frank J. Wolters et al.   PLoS One

Cardiovascular Risk Reduction with Icosapent Ethyl for Hypertriglyceridemia

(2018) Deepak L. Bhatt et al.   NEW ENGLAND JOURNAL OF MEDICINE

24-month intervention with a specific multinutrient in people with prodromal Alzheimer's disease (LipiDiDiet): a randomised, double-blind, controlled trial

(2017) Hilkka Soininen et al.   LANCET NEUROLOGY

Retroconversion is a minor contributor to increases in eicosapentaenoic acid following docosahexaenoic acid feeding as determined by compound specific isotope analysis in rat liver

(2017) Adam H. Metherel et al.   Nutrition & Metabolism

DHA brain uptake and APOE4 status: a PET study with [1-11C]-DHA

(2017) Hussein N. Yassine et al.   Alzheimers Research & Therapy

Apolipoprotein E Genotype and Sex Risk Factors for Alzheimer Disease

(2017) Scott C. Neu et al.   JAMA Neurology

Association of Docosahexaenoic Acid Supplementation With Alzheimer Disease Stage in Apolipoprotein E ε4 Carriers

(2017) Hussein N. Yassine et al.   JAMA Neurology

Measurement of Circulating Phospholipid Fatty Acids: Association between Relative Weight Percentage and Absolute Concentrations

(2016) Xiaoling Song et al.   JOURNAL OF THE AMERICAN COLLEGE OF NUTRITION

Influence of APOE Genotype on Hippocampal Atrophy over Time - An N=1925 Surface-Based ADNI Study

(2016) Bolun Li et al.   PLoS One

The effect of APOE genotype on the delivery of DHA to cerebrospinal fluid in Alzheimer’s disease

(2016) Hussein N. Yassine et al.   Alzheimers Research & Therapy

Association of Serum Docosahexaenoic Acid With Cerebral Amyloidosis

(2016) Hussein N. Yassine et al.   JAMA Neurology

The EADC-ADNI Harmonized Protocol for manual hippocampal segmentation on magnetic resonance: Evidence of validity

(2015) Giovanni B. Frisoni et al.   Alzheimers & Dementia

Delphi definition of the EADC-ADNI Harmonized Protocol for hippocampal segmentation on magnetic resonance

(2015) Marina Boccardi et al.   Alzheimers & Dementia

Interaction between BMI and APOE genotype is associated with changes in the plasma long-chain–PUFA response to a fish-oil supplement in healthy participants

(2015) Raphaël Chouinard-Watkins et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Relationship of medial temporal lobe atrophy, APOE genotype, and cognitive reserve in preclinical Alzheimer's disease

(2015) Anja Soldan et al.   HUMAN BRAIN MAPPING

Balancing proportions of competing omega-3 and omega-6 highly unsaturated fatty acids (HUFA) in tissue lipids

(2015) Doug Bibus et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

Genetic influence of apolipoprotein E4 genotype on hippocampal morphometry: AnN= 725 surface-based Alzheimer's disease neuroimaging initiative study

(2014) Jie Shi et al.   HUMAN BRAIN MAPPING

Higher RBC EPA + DHA corresponds with larger total brain and hippocampal volumes: WHIMS-MRI Study

(2014) J. V. Pottala et al.   NEUROLOGY

Apolipoprotein E isoforms disrupt long-chain fatty acid distribution in the plasma, the liver and the adipose tissue of mice

(2014) Valérie Conway et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

n-3 polyunsaturated fatty acids supplementation enhances hippocampal functionality in aged mice

(2014) Debora Cutuli et al.   Frontiers in Aging Neuroscience

Molecular Mechanisms Responsible for the Differential Effects of ApoE3 and ApoE4 on Plasma Lipoprotein–Cholesterol Levels

(2013) Hui Li et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Disturbance in uniformly 13C-labelled DHA metabolism in elderly human subjects carrying the apoE ε4 allele

(2013) R. Chouinard-Watkins et al.   BRITISH JOURNAL OF NUTRITION

Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy

(2013) Chia-Chen Liu et al.   Nature Reviews Neurology

Food-frequency questionnaire for assessing long-chain ω-3 fatty-acid intake

(2013) Connye Kuratko   NUTRITION

Red blood cell omega-3 fatty acid levels and markers of accelerated brain aging

(2012) Z. S. Tan et al.   NEUROLOGY

Phospholipase A2 and arachidonic acid in Alzheimer's disease

(2010) Rene O. Sanchez-Mejia et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Docosahexaenoic Acid Supplementation and Cognitive Decline in Alzheimer Disease

(2010) Joseph F. Quinn et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Excitotoxicity through Ca2+-permeable AMPA receptors requires Ca2+-dependent JNK activation

(2010) M. Vieira et al.   NEUROBIOLOGY OF DISEASE

Hippocampal atrophy rates and CSF biomarkers in elderly APOE2 normal subjects

(2010) G. C. Chiang et al.   NEUROLOGY

MRI of hippocampal volume loss in early Alzheimer's disease in relation to ApoE genotype and biomarkers

(2009) N. Schuff et al.   BRAIN

Fish, docosahexaenoic acid and Alzheimer’s disease

(2009) S.C. Cunnane et al.   PROGRESS IN LIPID RESEARCH

Phospholipase A2 reduction ameliorates cognitive deficits in a mouse model of Alzheimer's disease

(2008) Rene O Sanchez-Mejia et al.   NATURE NEUROSCIENCE

Dietary eicosapentaenoic acid and docosahexaenoic acid equally incorporate as decosahexaenoic acid but differ in inflammatory effects

(2008) Saleta Sierra et al.   NUTRITION