Intraperitoneal Administration of Monoclonal Antibody Against Pathologic Aβ42 Aggregates Alleviated Cognitive Deficits and Synaptic Lesions in APP/PS1 Mice

Trehalose reduces retinal degeneration, neuroinflammation and storage burden caused by a lysosomal hydrolase deficiency

(2018) Parisa Lotfi et al.   Autophagy

Administration of Amyloid-β42 Oligomer-Specific Monoclonal Antibody Improved Memory Performance in SAMP8 Mice

(2018) Ying Zhang et al.   JOURNAL OF ALZHEIMERS DISEASE

The potential of solanezumab and gantenerumab to prevent Alzheimer’s disease in people with inherited mutations that cause its early onset

(2017) Francesco Panza et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Amyloid β-Derived Diffusible Ligands (ADDLs) Induce Abnormal Autophagy Associated with Aβ Aggregation Degree

(2017) Jie Wen et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Human Brain-Derived Aβ Oligomers Bind to Synapses and Disrupt Synaptic Activity in a Manner That Requires APP

(2017) Zemin Wang et al.   JOURNAL OF NEUROSCIENCE

Single Chain Variable Fragment Against Aβ Expressed in Baculovirus Inhibits Abeta Fibril Elongation and Promotes its Disaggregation

(2015) Ying Zhang et al.   PLoS One

Regional distribution of synaptic markers and APP correlate with distinct clinicopathological features in sporadic and familial Alzheimer’s disease

(2014) Mitsuru Shinohara et al.   BRAIN

Oxidative stress and mitochondrial dysfunction in Alzheimer's disease

(2013) Xinglong Wang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Synthetic Tau Fibrils Mediate Transmission of Neurofibrillary Tangles in a Transgenic Mouse Model of Alzheimer's-Like Tauopathy

(2013) M. Iba et al.   JOURNAL OF NEUROSCIENCE

SAMP8 mice have altered hippocampal gene expression in long term potentiation, phosphatidylinositol signaling, and endocytosis pathways

(2013) Harvey J. Armbrecht et al.   NEUROBIOLOGY OF AGING

Evodiamine improves congnitive abilities in SAMP8 and APPswe/PS1ΔE9 transgenic mouse models of Alzheimer's disease

(2011) Shu-min Yuan et al.   ACTA PHARMACOLOGICA SINICA

Amyloid   Precursor Protein Regulates Male Sexual Behavior

(2010) J. H. Park et al.   JOURNAL OF NEUROSCIENCE

Modulation of γ-Secretase Reduces β-Amyloid Deposition in a Transgenic Mouse Model of Alzheimer's Disease

(2010) Maria Z. Kounnas et al.   NEURON

Suppression of Amyloid Deposition Leads to Long-Term Reductions in Alzheimer's Pathologies in Tg2576 Mice

(2009) R. A. Karlnoski et al.   JOURNAL OF NEUROSCIENCE