Pathogenesis of acute graft-versus-host disease: from intestinal microbiota alterations to donor T cell activation
出版年份 2016 全文链接
标题
Pathogenesis of acute graft-versus-host disease: from intestinal microbiota alterations to donor T cell activation
作者
关键词
-
出版物
BRITISH JOURNAL OF HAEMATOLOGY
Volume 175, Issue 2, Pages 191-207
出版商
Wiley
发表日期
2016-09-13
DOI
10.1111/bjh.14295
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Topical Ruxolitinib Protects LGR5+ Stem Cells in the Hair Follicle and Ameliorates Skin Graft-Versus-Host Disease
- (2016) Shuichiro Takahashi et al. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION
- No Evidence of Impact of Maraviroc on Outcome after Allogeneic Hematopoietic Stem Cell Transplant with Reduced Intensity Conditioning (RIC)
- (2016) William Adam Hammond et al. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION
- Atorvastatin for the Prophylaxis of Acute Graft-versus-Host Disease in Patients Undergoing HLA-Matched Related Donor Allogeneic Hematopoietic Stem Cell Transplantation (allo-HCT)
- (2016) Yvonne A. Efebera et al. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION
- Targeted Rho-associated kinase 2 inhibition suppresses murine and human chronic GVHD through a Stat3-dependent mechanism
- (2016) R. Flynn et al. BLOOD
- Caveolin-1 regulates TCR signal strength and regulatory T-cell differentiation into alloreactive T cells
- (2016) A. Schonle et al. BLOOD
- Peri-alloHCT IL-33 administration expands recipient T-regulatory cells that protect mice against acute GVHD
- (2016) B. M. Matta et al. BLOOD
- The PD-1 Axis Enforces an Anatomical Segregation of CTL Activity that Creates Tumor Niches after Allogeneic Hematopoietic Stem Cell Transplantation
- (2016) David Michonneau et al. IMMUNITY
- Metabolic reprogramming of alloantigen-activated T cells after hematopoietic cell transplantation
- (2016) Hung D. Nguyen et al. JOURNAL OF CLINICAL INVESTIGATION
- Normalizing the environment recapitulates adult human immune traits in laboratory mice
- (2016) Lalit K. Beura et al. NATURE
- Gut microbiome–derived metabolites modulate intestinal epithelial cell damage and mitigate graft-versus-host disease
- (2016) Nathan D Mathewson et al. NATURE IMMUNOLOGY
- Ipilimumab for Patients with Relapse after Allogeneic Transplantation
- (2016) Matthew S. Davids et al. NEW ENGLAND JOURNAL OF MEDICINE
- miR-146a and miR-155 Expression Levels in Acute Graft-Versus-Host Disease Incidence
- (2016) Sadaf Atarod et al. Frontiers in Immunology
- Interleukin-22: Immunobiology and Pathology
- (2015) Jarrod A. Dudakov et al. Annual Review of Immunology
- Targeting Syk-activated B cells in murine and human chronic graft-versus-host disease
- (2015) R. Flynn et al. BLOOD
- The IL-33/ST2 axis augments effector T-cell responses during acute GVHD
- (2015) D. K. Reichenbach et al. BLOOD
- MicroRNA-17-92 controls T-cell responses in graft-versus-host disease and leukemia relapse in mice
- (2015) Y. Wu et al. BLOOD
- B7-H3 expression in donor T cells and host cells negatively regulates acute graft-versus-host disease lethality
- (2015) R. G. Veenstra et al. BLOOD
- MicroRNA-155-deficient dendritic cells cause less severe GVHD through reduced migration and defective inflammasome activation
- (2015) S. Chen et al. BLOOD
- Umbilical cord blood-derived T regulatory cells to prevent GVHD: kinetics, toxicity profile, and clinical effect
- (2015) C. G. Brunstein et al. BLOOD
- Improved immune recovery after transplantation of TCRαβ/CD19-depleted allografts from haploidentical donors in pediatric patients
- (2015) P Lang et al. BONE MARROW TRANSPLANTATION
- Pharmacologic Inhibition of JAK1/JAK2 Signaling Reduces Experimental Murine Acute GVHD While Preserving GVT Effects
- (2015) C. Carniti et al. CLINICAL CANCER RESEARCH
- Retinoic Acid Is Essential for Th1 Cell Lineage Stability and Prevents Transition to a Th17 Cell Program
- (2015) Chrysothemis C. Brown et al. IMMUNITY
- Mature T cell responses are controlled by microRNA-142
- (2015) Yaping Sun et al. JOURNAL OF CLINICAL INVESTIGATION
- Donor colonic CD103+dendritic cells determine the severity of acute graft-versus-host disease
- (2015) Motoko Koyama et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Mechanistic Assessment of PD-1H Coinhibitory Receptor–Induced T Cell Tolerance to Allogeneic Antigens
- (2015) Dallas B. Flies et al. JOURNAL OF IMMUNOLOGY
- A Novel Function for P2Y2 in Myeloid Recipient–Derived Cells during Graft-versus-Host Disease
- (2015) Verena Klämbt et al. JOURNAL OF IMMUNOLOGY
- Interleukin-22 promotes intestinal-stem-cell-mediated epithelial regeneration
- (2015) Caroline A. Lindemans et al. NATURE
- LRRK2 and Nod2 promote lysozyme sorting in Paneth cells
- (2015) Juliana D B Rocha et al. NATURE IMMUNOLOGY
- PD-1 Blockade with Nivolumab in Relapsed or Refractory Hodgkin's Lymphoma
- (2015) Stephen M. Ansell et al. NEW ENGLAND JOURNAL OF MEDICINE
- ST2 blockade reduces sST2-producing T cells while maintaining protective mST2-expressing T cells during graft-versus-host disease
- (2015) Jilu Zhang et al. Science Translational Medicine
- Metagenomic Analysis of the Stool Microbiome in Patients Receiving Allogeneic Stem Cell Transplantation: Loss of Diversity Is Associated with Use of Systemic Antibiotics and More Pronounced in Gastrointestinal Graft-versus-Host Disease
- (2014) Ernst Holler et al. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION
- Donor CD4+ Foxp3+ regulatory T cells are necessary for posttransplantation cyclophosphamide-mediated protection against GVHD in mice
- (2014) S. Ganguly et al. BLOOD
- MiR-146a regulates the TRAF6/TNF-axis in donor T cells during GVHD
- (2014) N. Stickel et al. BLOOD
- Therapeutic activity of multiple common -chain cytokine inhibition in acute and chronic GVHD
- (2014) A.-K. Hechinger et al. BLOOD
- The effects of intestinal tract bacterial diversity on mortality following allogeneic hematopoietic stem cell transplantation
- (2014) Y. Taur et al. BLOOD
- HLA-haploidentical transplantation with regulatory and conventional T-cell adoptive immunotherapy prevents acute leukemia relapse
- (2014) M. F. Martelli et al. BLOOD
- Activity of therapeutic JAK 1/2 blockade in graft-versus-host disease
- (2014) S. Spoerl et al. BLOOD
- Microbiota-Generated Metabolites Promote Metabolic Benefits via Gut-Brain Neural Circuits
- (2014) Filipe De Vadder et al. CELL
- Serum microRNA155 is increased in patients with acute graft-versus-host disease
- (2014) Lin-Na Xie et al. CLINICAL TRANSPLANTATION
- The mucus and mucins of the goblet cells and enterocytes provide the first defense line of the gastrointestinal tract and interact with the immune system
- (2014) Thaher Pelaseyed et al. IMMUNOLOGICAL REVIEWS
- Multi-Institutional Study of Post-Transplantation Cyclophosphamide As Single-Agent Graft-Versus-Host Disease Prophylaxis After Allogeneic Bone Marrow Transplantation Using Myeloablative Busulfan and Fludarabine Conditioning
- (2014) Christopher G. Kanakry et al. JOURNAL OF CLINICAL ONCOLOGY
- The Indoleamine 2,3-Dioxygenase Pathway Is Essential for Human Plasmacytoid Dendritic Cell-Induced Adaptive T Regulatory Cell Generation
- (2014) W. Chen et al. JOURNAL OF IMMUNOLOGY
- Interleukin-22 Aggravates Murine Acute Graft-Versus-Host Disease by Expanding Effector T Cell and Reducing Regulatory T Cell
- (2014) Kai Zhao et al. JOURNAL OF INTERFERON AND CYTOKINE RESEARCH
- Addition of interleukin-6 inhibition with tocilizumab to standard graft-versus-host disease prophylaxis after allogeneic stem-cell transplantation: a phase 1/2 trial
- (2014) Glen A Kennedy et al. LANCET ONCOLOGY
- Neutrophil granulocytes recruited upon translocation of intestinal bacteria enhance graft-versus-host disease via tissue damage
- (2014) Lukas Schwab et al. NATURE MEDICINE
- Role of Lymphocyte Activation Gene-3 (Lag-3) in Conventional and Regulatory T Cell Function in Allogeneic Transplantation
- (2014) Emanuela I. Sega et al. PLoS One
- In Vivo T Cell Costimulation Blockade with Abatacept for Acute Graft-versus-Host Disease Prevention: A First-in-Disease Trial
- (2013) Divya T. Koura et al. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION
- Inflammatory neovascularization during graft-versus-host disease is regulated by v integrin and miR-100
- (2013) F. Leonhardt et al. BLOOD
- Host programmed death ligand 1 is dominant over programmed death ligand 2 expression in regulating graft-versus-host disease lethality
- (2013) A. Saha et al. BLOOD
- Effector T cells require fatty acid metabolism during murine graft-versus-host disease
- (2013) C. A. Byersdorfer et al. BLOOD
- Inhibiting retinoic acid signaling ameliorates graft-versus-host disease by modifying T-cell differentiation and intestinal migration
- (2013) K. Aoyama et al. BLOOD
- Plasma microRNA signature as a noninvasive biomarker for acute graft-versus-host disease
- (2013) B. Xiao et al. BLOOD
- Sibling Donor and Recipient Immune Modulation With Atorvastatin for the Prophylaxis of Acute Graft-Versus-Host Disease
- (2013) Mehdi Hamadani et al. JOURNAL OF CLINICAL ONCOLOGY
- The Nlrp3 inflammasome regulates acute graft-versus-host disease
- (2013) Dragana Jankovic et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Treg induction by a rationally selected mixture of Clostridia strains from the human microbiota
- (2013) Koji Atarashi et al. NATURE
- FTY720 Markedly Increases Alloengraftment but Does Not Eliminate Host Anti-Donor T Cells that Cause Graft Rejection on Its Withdrawal
- (2012) Patricia A. Taylor et al. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION
- First- and Second-Line Systemic Treatment of Acute Graft-versus-Host Disease: Recommendations of the American Society of Blood and Marrow Transplantation
- (2012) Paul J. Martin et al. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION
- Contrasting acute graft-versus-host disease effects of Tim-3/galectin-9 pathway blockade dependent upon the presence of donor regulatory T cells
- (2012) R. G. Veenstra et al. BLOOD
- Graft-versus-host disease disrupts intestinal microbial ecology by inhibiting Paneth cell production of -defensins
- (2012) Y. Eriguchi et al. BLOOD
- Regulation of acute graft-versus-host disease by microRNA-155
- (2012) P. Ranganathan et al. BLOOD
- Inhibition of protein geranylgeranylation and farnesylation protects against graft-versus-host disease via effects on CD4 effector T cells
- (2012) A.-K. Hechinger et al. HAEMATOLOGICA
- Interleukin-22 Protects Intestinal Stem Cells from Immune-Mediated Tissue Damage and Regulates Sensitivity to Graft versus Host Disease
- (2012) Alan M. Hanash et al. IMMUNITY
- Bortezomib-Based Graft-Versus-Host Disease Prophylaxis in HLA-Mismatched Unrelated Donor Transplantation
- (2012) John Koreth et al. JOURNAL OF CLINICAL ONCOLOGY
- Regulation of intestinal inflammation by microbiota following allogeneic bone marrow transplantation
- (2012) Robert R. Jenq et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Profound Depletion of Host Conventional Dendritic Cells, Plasmacytoid Dendritic Cells, and B Cells Does Not Prevent Graft-versus-Host Disease Induction
- (2012) H. Li et al. JOURNAL OF IMMUNOLOGY
- Blockade of Lymphocyte Chemotaxis in Visceral Graft-versus-Host Disease
- (2012) Ran Reshef et al. NEW ENGLAND JOURNAL OF MEDICINE
- IDO in Human Gut Graft-versus-Host Disease
- (2011) Philippe Ratajczak et al. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION
- Blocking IL-21 signaling ameliorates xenogeneic GVHD induced by human lymphocytes
- (2011) K. L. Hippen et al. BLOOD
- Abrogation of donor T-cell IL-21 signaling leads to tissue-specific modulation of immunity and separation of GVHD from GVL
- (2011) A. M. Hanash et al. BLOOD
- Induction of acute GVHD by sex-mismatched H-Y antigens in the absence of functional radiosensitive host hematopoietic-derived antigen-presenting cells
- (2011) T. Toubai et al. BLOOD
- Dichotomous regulation of GVHD through bidirectional functions of the BTLA-HVEM pathway
- (2011) Y. Sakoda et al. BLOOD
- Tregs prevent GVHD and promote immune reconstitution in HLA-haploidentical transplantation
- (2011) M. Di Ianni et al. BLOOD
- IL-33 synergizes with TCR and IL-12 signaling to promote the effector function of CD8+T cells
- (2011) Qianting Yang et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Vstm3 is a member of the CD28 family and an important modulator of T-cell function
- (2011) Steven D. Levin et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Integrated T-cell receptor and costimulatory signals determine TGF-β-dependent differentiation and maintenance of Foxp3+ regulatory T cells
- (2011) Leona Gabryšová et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Pretransplant CSF-1 therapy expands recipient macrophages and ameliorates GVHD after allogeneic hematopoietic cell transplantation
- (2011) Daigo Hashimoto et al. JOURNAL OF EXPERIMENTAL MEDICINE
- The Wnt agonist R-spondin1 regulates systemic graft-versus-host disease by protecting intestinal stem cells
- (2011) Shuichiro Takashima et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Silencing MicroRNA-155 Ameliorates Experimental Autoimmune Encephalomyelitis
- (2011) G. Murugaiyan et al. JOURNAL OF IMMUNOLOGY
- Recipient nonhematopoietic antigen-presenting cells are sufficient to induce lethal acute graft-versus-host disease
- (2011) Motoko Koyama et al. NATURE MEDICINE
- Retinoic Acid and Rapamycin Differentially Affect and Synergistically Promote the Ex Vivo Expansion of Natural Human T Regulatory Cells
- (2011) Tatiana N. Golovina et al. PLoS One
- PD-L1 blockade effectively restores strong graft-versus-leukemia effects without graft-versus-host disease after delayed adoptive transfer of T-cell receptor gene-engineered allogeneic CD8+ T cells
- (2010) W. Koestner et al. BLOOD
- Blockade of interleukin-23 signaling results in targeted protection of the colon and allows for separation of graft-versus-host and graft-versus-leukemia responses
- (2010) R. Das et al. BLOOD
- SMAD3 prevents graft-versus-host disease by restraining Th1 differentiation and granulocyte-mediated tissue damage
- (2010) M. Giroux et al. BLOOD
- Infusion of ex vivo expanded T regulatory cells in adults transplanted with umbilical cord blood: safety profile and detection kinetics
- (2010) C. G. Brunstein et al. BLOOD
- Bone marrow myeloid-derived suppressor cells (MDSCs) inhibit graft-versus-host disease (GVHD) via an arginase-1-dependent mechanism that is up-regulated by interleukin-13
- (2010) S. L. Highfill et al. BLOOD
- Interleukin-2 receptor downstream events in regulatory T cells: Implications for the choice of immunosuppressive drug therapy
- (2010) Robert Zeiser et al. CELL CYCLE
- Interleukin-6 Modulates Graft-versus-Host Responses after Experimental Allogeneic Bone Marrow Transplantation
- (2010) I. Tawara et al. CLINICAL CANCER RESEARCH
- Alloantigen expression on non-hematopoietic cells reduces graft-versus-leukemia effects in mice
- (2010) Shoji Asakura et al. JOURNAL OF CLINICAL INVESTIGATION
- TCR ligand density and affinity determine peripheral induction of Foxp3 in vivo
- (2010) Rachel A. Gottschalk et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Graft-versus-host disease is enhanced by extracellular ATP activating P2X7R
- (2010) Konrad Wilhelm et al. NATURE MEDICINE
- Plasmacytoid dendritic cells prime alloreactive T cells to mediate graft-versus-host disease as antigen-presenting cells
- (2009) M. Koyama et al. BLOOD
- Inducing the tryptophan catabolic pathway, indoleamine 2,3-dioxygenase (IDO), for suppression of graft-versus-host disease (GVHD) lethality
- (2009) L. K. Jasperson et al. BLOOD
- IL-21 blockade reduces graft-versus-host disease mortality by supporting inducible T regulatory cell generation
- (2009) C. Bucher et al. BLOOD
- Donor statin treatment protects against severe acute graft-versus-host disease after related allogeneic hematopoietic cell transplantation
- (2009) M. Rotta et al. BLOOD
- Graft-versus-host disease: regulation by microbe-associated molecules and innate immune receptors
- (2009) O. Penack et al. BLOOD
- Blockade of interleukin-6 signaling augments regulatory T-cell reconstitution and attenuates the severity of graft-versus-host disease
- (2009) X. Chen et al. BLOOD
- Addition of Infliximab to Standard Acute Graft-versus-Host Disease Prophylaxis following Allogeneic Peripheral Blood Cell Transplantation
- (2008) Mehdi Hamadani et al. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION
- CTLA4 blockade with ipilimumab to treat relapse of malignancy after allogeneic hematopoietic cell transplantation
- (2008) A. Bashey et al. BLOOD
- STAT-3 and ERK 1/2 phosphorylation are critical for T-cell alloactivation and graft-versus-host disease
- (2008) S. X. Lu et al. BLOOD
- Control of protein synthesis and mRNA degradation by microRNAs
- (2008) Jidong Liu CURRENT OPINION IN CELL BIOLOGY
- The surface protein TIGIT suppresses T cell activation by promoting the generation of mature immunoregulatory dendritic cells
- (2008) Xin Yu et al. NATURE IMMUNOLOGY
- Indoleamine 2,3-dioxygenase is a critical regulator of acute graft-versus-host disease lethality
- (2007) L. K. Jasperson et al. BLOOD
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