Glial Asthenia and Functional Paralysis

Reexamining Alzheimer's Disease: Evidence for a Protective Role for Amyloid-β Protein Precursor and Amyloid-β

(2017) Rudy J. Castellani et al.   JOURNAL OF ALZHEIMERS DISEASE

Astrocyte glutamine synthetase: pivotal in health and disease

(2015) Christopher F. Rose et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Myelin Membrane Wrapping of CNS Axons by PI(3,4,5)P3-Dependent Polarized Growth at the Inner Tongue

(2014) Nicolas Snaidero et al.   CELL

Differential deregulation of astrocytic calcium signalling by amyloid-β, TNFα, IL-1β and LPS

(2014) Virginia Ronco et al.   CELL CALCIUM

Astrocytosis measured by 11C-deprenyl PET correlates with decrease in gray matter density in the parahippocampus of prodromal Alzheimer’s patients

(2014) IL Han Choo et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Molecular Imaging in Sporadic Alzheimer's Disease Populations and Those Genetically at Risk

(2014) Agneta Nordberg   Neurodegenerative Diseases

Reactive Gliosis and the Multicellular Response to CNS Damage and Disease

(2014) Joshua E. Burda et al.   NEURON

Strippers Reveal Their Depressing Secrets: Removing AMPA Receptors

(2014) Graham L. Collingridge et al.   NEURON

The dual role of astrocyte activation and reactive gliosis

(2014) Milos Pekny et al.   NEUROSCIENCE LETTERS

Microglial Dynamics and Role in the Healthy and Diseased Brain

(2014) Diego Gomez-Nicola et al.   NEUROSCIENTIST

Astroglial cradle in the life of the synapse

(2014) A. Verkhratsky et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Myelin--More than Insulation

(2014) R. D. Fields   SCIENCE

Microglial response to Alzheimer’s disease is differentially modulated by voluntary wheel running and enriched environments

(2013) J. J. Rodríguez et al.   Brain Structure & Function

Microglial Senescence

(2013) Wolfgang Streit et al.   CNS & Neurological Disorders-Drug Targets

Neuronal and glial alterations, increased anxiety, and cognitive impairment before hippocampal amyloid deposition in PDAPP mice, model of Alzheimer's disease

(2013) Juan Beauquis et al.   HIPPOCAMPUS

3H-Deprenyl and 3H-PIB autoradiography show different laminar distributions of astroglia and fibrillar β-amyloid in Alzheimer brain

(2013) Amelia Marutle et al.   Journal of Neuroinflammation

Ammonia triggers neuronal disinhibition and seizures by impairing astrocyte potassium buffering

(2013) Vinita Rangroo Thrane et al.   NATURE MEDICINE

Microglia emerge from erythromyeloid precursors via Pu.1- and Irf8-dependent pathways

(2013) Katrin Kierdorf et al.   NATURE NEUROSCIENCE

Enhanced Ca2+-dependent glutamate release from astrocytes of the BACHD Huntington's disease mouse model

(2013) William Lee et al.   NEUROBIOLOGY OF DISEASE

Microglia: New Roles for the Synaptic Stripper

(2013) Helmut Kettenmann et al.   NEURON

Astrogliopathology

(2013) Alexei Verkhratsky et al.   NEUROSCIENTIST

Functional Impairment of Microglia Coincides with Beta-Amyloid Deposition in Mice with Alzheimer-Like Pathology

(2013) Grietje Krabbe et al.   PLoS One

Calcium-dependent N-cadherin up-regulation mediates reactive astrogliosis and neuroprotection after brain injury

(2013) K. Kanemaru et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Microglia and macrophages of the central nervous system: the contribution of microglia priming and systemic inflammation to chronic neurodegeneration

(2013) V. Hugh Perry et al.   Seminars in Immunopathology

Amyloid-β and Alzheimer’s disease type pathology differentially affects the calcium signalling toolkit in astrocytes from different brain regions

(2013) A A Grolla et al.   Cell Death & Disease

Neurological Diseases as Primary Gliopathies: A Reassessment of Neurocentrism

(2012) Alexei Verkhratsky et al.   ASN Neuro

Environmental enrichment prevents astroglial pathological changes in the hippocampus of APP transgenic mice, model of Alzheimer's disease

(2012) Juan Beauquis et al.   EXPERIMENTAL NEUROLOGY

Attenuating astrocyte activation accelerates plaque pathogenesis in APP/PS1 mice

(2012) Andrew W. Kraft et al.   FASEB JOURNAL

Artifact versus reality-How astrocytes contribute to synaptic events

(2012) Maiken Nedergaard et al.   GLIA

Effects of aging and sensory loss on glial cells in mouse visual and auditory cortices

(2012) Marie-Ève Tremblay et al.   GLIA

Astrocytic regulation of glutamate homeostasis in epilepsy

(2012) Douglas A. Coulter et al.   GLIA

Astrocytic cytoskeletal atrophy in the medial prefrontal cortex of a triple transgenic mouse model of Alzheimer’s disease

(2012) Magdalena Kulijewicz-Nawrot et al.   JOURNAL OF ANATOMY

Glial cells in (patho)physiology

(2012) Vladimir Parpura et al.   JOURNAL OF NEUROCHEMISTRY

Alexander Disease

(2012) A. Messing et al.   JOURNAL OF NEUROSCIENCE

Evidence for Astrocytosis in Prodromal Alzheimer Disease Provided by 11C-Deuterium-L-Deprenyl: A Multitracer PET Paradigm Combining 11C-Pittsburgh Compound B and 18F-FDG

(2012) S. F. Carter et al.   JOURNAL OF NUCLEAR MEDICINE

Glia and Methylmercury Neurotoxicity

(2012) Mingwei Ni et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES

Plasticity in gray and white: neuroimaging changes in brain structure during learning

(2012) Robert J Zatorre et al.   NATURE NEUROSCIENCE

TREM2 Variants in Alzheimer's Disease

(2012) Rita Guerreiro et al.   NEW ENGLAND JOURNAL OF MEDICINE

Alzheimer's disease models and functional genomics—How many needles are there in the haystack?

(2012) Jürgen Götz et al.   Frontiers in Physiology

Early Astrocytic Atrophy in the Entorhinal Cortex of a Triple Transgenic Animal Model of Alzheimer's Disease

(2011) Chia-Yu Yeh et al.   ASN Neuro

Neuron–astrocyte signaling and epilepsy

(2011) Gerald Seifert et al.   EXPERIMENTAL NEUROLOGY

The evolutionary origins of glia

(2011) Daniel K. Hartline   GLIA

The Role of Microglia in the Healthy Brain

(2011) M.-E. Tremblay et al.   JOURNAL OF NEUROSCIENCE

Compounding artefacts with uncertainty, and an amyloid cascade hypothesis that is ‘too big to fail’

(2011) Rudy J Castellani et al.   JOURNAL OF PATHOLOGY

Omnis cellula e cellula revisited: cell biology as the foundation of pathology

(2011) Nicholas A Wright et al.   JOURNAL OF PATHOLOGY

Age-dependent decrease in glutamine synthetase expression in the hippocampal astroglia of the triple transgenic Alzheimer's disease mouse model: mechanism for deficient glutamatergic transmission?

(2011) Markel Olabarria et al.   Molecular Neurodegeneration

The amyloid cascade hypothesis for Alzheimer's disease: an appraisal for the development of therapeutics

(2011) Eric Karran et al.   NATURE REVIEWS DRUG DISCOVERY

NG2-glia as Multipotent Neural Stem Cells: Fact or Fantasy?

(2011) William D. Richardson et al.   NEURON

Physiology of Microglia

(2011) Helmut Kettenmann et al.   PHYSIOLOGICAL REVIEWS

Brain Glucose Hypometabolism and Oxidative Stress in Preclinical Alzheimer's Disease

(2010) Lisa Mosconi et al.   Annals of the New York Academy of Sciences

Hematopoietic Origin of Pathological Grooming in Hoxb8 Mutant Mice

(2010) Shau-Kwaun Chen et al.   CELL

Microglia in the degenerating brain are capable of phagocytosis of beads and of apoptotic cells, but do not efficiently remove PrPSc, even upon LPS stimulation

(2010) Martina M. Hughes et al.   GLIA

Rett Syndrome Microglia Damage Dendrites and Synapses by the Elevated Release of Glutamate

(2010) I. Maezawa et al.   JOURNAL OF NEUROSCIENCE

Regulation of synaptic connectivity by glia

(2010) Cagla Eroglu et al.   NATURE

The use of PET in Alzheimer disease

(2010) Agneta Nordberg et al.   Nature Reviews Neurology

Microglia in neurodegenerative disease

(2010) V. Hugh Perry et al.   Nature Reviews Neurology

Altered glial–neuronal crosstalk: Cornerstone in the pathogenesis of hepatic encephalopathy

(2010) Roger F. Butterworth   NEUROCHEMISTRY INTERNATIONAL

Probing the Biology of Alzheimer's Disease in Mice

(2010) Karen H. Ashe et al.   NEURON

Astrocytes in Alzheimer’s disease

(2010) Alexei Verkhratsky et al.   Neurotherapeutics

Astrocyte glutamine synthetase: Importance in hyperammonemic syndromes and potential target for therapy

(2010) Saul W. Brusilow et al.   Neurotherapeutics

Metal Toxicity, Liver Disease and Neurodegeneration

(2010) Roger F. Butterworth   NEUROTOXICITY RESEARCH

Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages

(2010) F. Ginhoux et al.   SCIENCE

Increase in the density of resting microglia precedes neuritic plaque formation and microglial activation in a transgenic model of Alzheimer's disease

(2010) J J Rodríguez et al.   Cell Death & Disease

Neurovascular mechanisms and blood–brain barrier disorder in Alzheimer’s disease

(2009) Robert D. Bell et al.   ACTA NEUROPATHOLOGICA

Astrocytes: biology and pathology

(2009) Michael V. Sofroniew et al.   ACTA NEUROPATHOLOGICA

Microglial Physiology: Unique Stimuli, Specialized Responses

(2009) Richard M. Ransohoff et al.   Annual Review of Immunology

Astrocytic dysfunction: Insights on the role in neurodegeneration

(2009) Daniela Rossi et al.   BRAIN RESEARCH BULLETIN

Neuroglia in neurodegeneration

(2009) Michael T. Heneka et al.   BRAIN RESEARCH REVIEWS

Calcium dyshomeostasis in white matter pathology

(2009) Carlos Matute   CELL CALCIUM

Adenosine signaling and function in glial cells

(2009) D Boison et al.   CELL DEATH AND DIFFERENTIATION

Population Variation in Glial Fibrillary Acidic Protein Levels in Brain Ageing: Relationship to Alzheimer-Type Pathology and Dementia

(2009) S.B. Wharton et al.   DEMENTIA AND GERIATRIC COGNITIVE DISORDERS

The amyloid hypothesis for Alzheimer’s disease: a critical reappraisal

(2009) John Hardy   JOURNAL OF NEUROCHEMISTRY

Rett Syndrome Astrocytes Are Abnormal and Spread MeCP2 Deficiency through Gap Junctions

(2009) I. Maezawa et al.   JOURNAL OF NEUROSCIENCE

Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease

(2009) Jean-Charles Lambert et al.   NATURE GENETICS

The phylogeny of invertebrates and the evolution of myelin

(2009) Betty I. Roots   Neuron Glia Biology

Synchronous Hyperactivity and Intercellular Calcium Waves in Astrocytes in Alzheimer Mice

(2009) K. V. Kuchibhotla et al.   SCIENCE

Molecular dissection of reactive astrogliosis and glial scar formation

(2009) Michael V. Sofroniew   TRENDS IN NEUROSCIENCES

The amyloid cascade hypothesis

(2008) Amos D. Korczyn   Alzheimers & Dementia

Focal degeneration of astrocytes in amyotrophic lateral sclerosis

(2008) D Rossi et al.   CELL DEATH AND DIFFERENTIATION

Astroglia in dementia and Alzheimer's disease

(2008) J J Rodríguez et al.   CELL DEATH AND DIFFERENTIATION

The origin of the myelination program in vertebrates

(2008) B. Zalc et al.   CURRENT BIOLOGY

Triple-transgenic Alzheimer's disease mice exhibit region-specific abnormalities in brain myelination patterns prior to appearance of amyloid and tau pathology

(2008) Maya K. Desai et al.   GLIA

Astrocytes as determinants of disease progression in inherited amyotrophic lateral sclerosis

(2008) Koji Yamanaka et al.   NATURE NEUROSCIENCE

Polydendrocytes (NG2 cells): multifunctional cells with lineage plasticity

(2008) Akiko Nishiyama et al.   NATURE REVIEWS NEUROSCIENCE

Astrocyte phenotype in relation to Alzheimer-type pathology in the ageing brain

(2008) J.E. Simpson et al.   NEUROBIOLOGY OF AGING

The Blood-Brain Barrier in Health and Chronic Neurodegenerative Disorders

(2008) Berislav V. Zlokovic   NEURON

Oligodendrocytes Changing the Rules: Action Potentials in Glia and Oligodendrocytes Controlling Action Potentials

(2008) R. Douglas Fields   NEUROSCIENTIST

NEUROSCIENCE: A New Glance at Glia

(2008) A. Reichenbach et al.   SCIENCE

Glia Are Essential for Sensory Organ Function in C. elegans

(2008) T. Bacaj et al.   SCIENCE

White matter in learning, cognition and psychiatric disorders

(2008) R. Douglas Fields   TRENDS IN NEUROSCIENCES

Dysfunctional astrocytes as key players in the pathogenesis of central nervous system disorders

(2007) Jacques De Keyser et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES