标题
Noninvasive Molecular Imaging of Neuroinflammation
作者
关键词
-
出版物
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
Volume 32, Issue 7, Pages 1393-1415
出版商
SAGE Publications
发表日期
2012-05-02
DOI
10.1038/jcbfm.2012.53
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Quantitative Preclinical Imaging of TSPO Expression in Glioma Using N,N-Diethyl-2-(2-(4-(2-18F-Fluoroethoxy)Phenyl)-5,7-Dimethylpyrazolo[1,5-a]Pyrimidin-3-yl)Acetamide
- (2012) D. Tang et al. JOURNAL OF NUCLEAR MEDICINE
- 125I-Labeled Gold Nanorods for Targeted Imaging of Inflammation
- (2011) Xia Shao et al. ACS Nano
- PET/CT in diagnosis of dementia
- (2011) Valentina Berti et al. Annals of the New York Academy of Sciences
- Fluorinated cannabinoid CB2 receptor ligands: Synthesis and in vitro binding characteristics of 2-oxoquinoline derivatives
- (2011) Nashaat Turkman et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Brain inflammation is induced by co-morbidities and risk factors for stroke
- (2011) Caroline Drake et al. BRAIN BEHAVIOR AND IMMUNITY
- Toll-like receptors 7 and 8 expression is associated with poor outcome and greater inflammatory response in acute ischemic stroke
- (2011) David Brea et al. CLINICAL IMMUNOLOGY
- Microglia Phenotype Diversity
- (2011) M. Olah et al. CNS & Neurological Disorders-Drug Targets
- The Yin and Yang of Microglia
- (2011) Melinda Czeh et al. DEVELOPMENTAL NEUROSCIENCE
- Imaging of neuroinflammation
- (2011) Andrea Ciarmiello EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
- Evaluation of [123I]-CLINDE as a potent SPECT radiotracer to assess the degree of astroglia activation in cuprizone-induced neuroinflammation
- (2011) Filomena Mattner et al. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
- Adapted focal experimental autoimmune encephalomyelitis to allow MRI exploration of multiple sclerosis features
- (2011) Thomas Tourdias et al. EXPERIMENTAL NEUROLOGY
- Role of microglia in CNS inflammation
- (2011) Manuel B. Graeber et al. FEBS LETTERS
- In Vivo Analysis of Uropod Function during Physiological T Cell Trafficking
- (2011) S. F. Soriano et al. JOURNAL OF IMMUNOLOGY
- Clinical and imaging correlates of the multiple sclerosis impact scale in secondary progressive multiple sclerosis
- (2011) T. Hayton et al. JOURNAL OF NEUROLOGY
- A PET Brain Reporter Gene System Based on Type 2 Cannabinoid Receptors
- (2011) C. Vandeputte et al. JOURNAL OF NUCLEAR MEDICINE
- In Vivo Expression of Cyclooxygenase-1 in Activated Microglia and Macrophages During Neuroinflammation Visualized by PET with 11C-Ketoprofen Methyl Ester
- (2011) M. Shukuri et al. JOURNAL OF NUCLEAR MEDICINE
- Circulating CD133+CD34+ progenitor cells inversely correlate with soluble ICAM-1 in early ischemic stroke patients
- (2011) Tanya Bogoslovsky et al. Journal of Translational Medicine
- Stroke and the immune system: from pathophysiology to new therapeutic strategies
- (2011) Richard Macrez et al. LANCET NEUROLOGY
- Infiltrating monocytes trigger EAE progression, but do not contribute to the resident microglia pool
- (2011) Bahareh Ajami et al. NATURE NEUROSCIENCE
- In Vivo Imaging Reveals Distinct Inflammatory Activity of CNS Microglia versus PNS Macrophages in a Mouse Model for ALS
- (2011) Payam Dibaj et al. PLoS One
- Detection and monitoring of the multiple inflammatory responses by photoacoustic molecular imaging using selectively targeted gold nanorods
- (2011) Seunghan Ha et al. Biomedical Optics Express
- Radiosynthesis of [18F]fluoromethyldeoxyspergualin for molecular imaging of heat shock proteins
- (2010) Pradip Ghosh et al. APPLIED RADIATION AND ISOTOPES
- Synthesis and biodistribution of [11C]A-836339, a new potential radioligand for PET imaging of cannabinoid type 2 receptors (CB2)
- (2010) Andrew G. Horti et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Positron emission tomography imaging and clinical progression in relation to molecular pathology in the first Pittsburgh Compound B positron emission tomography patient with Alzheimer’s disease
- (2010) Ahmadul Kadir et al. BRAIN
- Mechanisms Underlying Inflammation in Neurodegeneration
- (2010) Christopher K. Glass et al. CELL
- Microglia dynamics and function in the CNS
- (2010) Christopher N Parkhurst et al. CURRENT OPINION IN NEUROBIOLOGY
- New approaches to neuroimaging of central nervous system inflammation
- (2010) Guido Stoll et al. CURRENT OPINION IN NEUROLOGY
- Positron emission tomography imaging in multiple sclerosis-current status and future applications
- (2010) L. Kiferle et al. EUROPEAN JOURNAL OF NEUROLOGY
- In vivo imaging of neuroinflammation in the rodent brain with [11C]SSR180575, a novel indoleacetamide radioligand of the translocator protein (18 kDa)
- (2010) Fabien Chauveau et al. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
- In vivo imaging of neuroinflammation: a comparative study between [18F]PBR111, [11C]CLINME and [11C]PK11195 in an acute rodent model
- (2010) Nadja Van Camp et al. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
- In vivo changes in microglial activation and amyloid deposits in brain regions with hypometabolism in Alzheimer’s disease
- (2010) Masamichi Yokokura et al. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
- Treatment with minocycline after disease onset alters astrocyte reactivity and increases microgliosis in SOD1 mutant mice
- (2010) A. Florence Keller et al. EXPERIMENTAL NEUROLOGY
- Superior sensitivity of novel molecular imaging probe: simultaneously targeting two types of endothelial injury markers
- (2010) Dawei Sun et al. FASEB JOURNAL
- Time-dependent changes in proinflammatory and neurotrophic responses of microglia and astrocytes in a rat model of osmotic demyelination syndrome
- (2010) Shintaro Iwama et al. GLIA
- Translocator protein (18 kDa)/peripheral benzodiazepine receptor specific ligands induce microglia functions consistent with an activated state
- (2010) Judy Choi et al. GLIA
- In Vivo Imaging of Partially Reversible Th17 Cell-Induced Neuronal Dysfunction in the Course of Encephalomyelitis
- (2010) Volker Siffrin et al. IMMUNITY
- Inflammation in neurodegenerative diseases
- (2010) Sandra Amor et al. IMMUNOLOGY
- In Vivo Volumetric Intravascular Ultrasound Visualization of Early/Inflammatory Arterial Atheroma Using Targeted Echogenic Immunoliposomes
- (2010) Hyunggun Kim et al. INVESTIGATIVE RADIOLOGY
- Molecular Magnetic Resonance Imaging of Acute Vascular Cell Adhesion Molecule-1 Expression in a Mouse Model of Cerebral Ischemia
- (2010) Lisa C Hoyte et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Differential Roles for Endothelial ICAM-1, ICAM-2, and VCAM-1 in Shear-Resistant T Cell Arrest, Polarization, and Directed Crawling on Blood-Brain Barrier Endothelium
- (2010) O. Steiner et al. JOURNAL OF IMMUNOLOGY
- Neuroinflammatory processes in Alzheimer’s disease
- (2010) Michael T. Heneka et al. JOURNAL OF NEURAL TRANSMISSION
- Mixed-Affinity Binding in Humans with 18-kDa Translocator Protein Ligands
- (2010) D. R. J. Owen et al. JOURNAL OF NUCLEAR MEDICINE
- The Temporal Dynamics of Poststroke Neuroinflammation: A Longitudinal Diffusion Tensor Imaging-Guided PET Study with 11C-PK11195 in Acute Subcortical Stroke
- (2010) A. Thiel et al. JOURNAL OF NUCLEAR MEDICINE
- Quantitative, Preclinical PET of Translocator Protein Expression in Glioma Using 18F-N-Fluoroacetyl-N-(2,5-Dimethoxybenzyl)-2-Phenoxyaniline
- (2010) J. R. Buck et al. JOURNAL OF NUCLEAR MEDICINE
- Advanced MRI and PET imaging for assessment of treatment response in patients with gliomas
- (2010) Frederic G Dhermain et al. LANCET NEUROLOGY
- Reduced PBR/TSPO Expression After Minocycline Treatment in a Rat Model of Focal Cerebral Ischemia: A PET Study Using [18F]DPA-714
- (2010) Abraham Martín et al. MOLECULAR IMAGING AND BIOLOGY
- Translocator protein (18 kDa) (TSPO) as a therapeutic target for neurological and psychiatric disorders
- (2010) Rainer Rupprecht et al. NATURE REVIEWS DRUG DISCOVERY
- Microglia in neurodegenerative disease
- (2010) V. Hugh Perry et al. Nature Reviews Neurology
- Activated MAO-B in the brain of Alzheimer patients, demonstrated by [11C]-l-deprenyl using whole hemisphere autoradiography
- (2010) Balázs Gulyás et al. NEUROCHEMISTRY INTERNATIONAL
- The Science of Stroke: Mechanisms in Search of Treatments
- (2010) Michael A. Moskowitz et al. NEURON
- The time window of MRI of murine atherosclerotic plaques after administration of CB2 receptor targeted micelles: inter-scan variability and relation between plaque signal intensity increase and gadolinium content of inversion recovery prepared versus non-
- (2010) B. C. M. te Boekhorst et al. NMR IN BIOMEDICINE
- Calpain 2 Controls Turnover of LFA-1 Adhesions on Migrating T Lymphocytes
- (2010) Lena Svensson et al. PLoS One
- Locus ceruleus controls Alzheimer's disease pathology by modulating microglial functions through norepinephrine
- (2010) M. T. Heneka et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages
- (2010) F. Ginhoux et al. SCIENCE
- Knocking at the brain’s door: intravital two-photon imaging of autoreactive T cell interactions with CNS structures
- (2010) Naoto Kawakami et al. Seminars in Immunopathology
- Intracellular Nanoparticle Coating Stability Determines Nanoparticle Diagnostics Efficacy and Cell Functionality
- (2010) Stefaan J. H. Soenen et al. Small
- Minocycline to Improve Neurologic Outcome in Stroke (MINOS)
- (2010) Susan C. Fagan et al. STROKE
- A Simple Positron Emission Tomography-Based Calibration for Perfusion-Weighted Magnetic Resonance Maps to Optimize Penumbral Flow Detection in Acute Stroke
- (2010) Olivier Zaro-Weber et al. STROKE
- Multimodal microglia imaging of fiber tracts in acute subcortical stroke
- (2009) Basia A. Radlinska et al. ANNALS OF NEUROLOGY
- Myocardial Ischemia/Reperfusion Injury Is Mediated by Leukocytic Toll-Like Receptor-2 and Reduced by Systemic Administration of a Novel Anti–Toll-Like Receptor-2 Antibody
- (2009) Fatih Arslan et al. CIRCULATION
- Functional and Molecular Ultrasound Imaging: Concepts and Contrast Agents
- (2009) F. Kiessling et al. CURRENT MEDICINAL CHEMISTRY
- Radiolabelled Molecules for Imaging the Translocator Protein (18 kDa) Using Positron Emission Tomography
- (2009) Frederic Dolle et al. CURRENT MEDICINAL CHEMISTRY
- Spatial diversity of blood–brain barrier alteration and macrophage invasion in experimental autoimmune encephalomyelitis: A comparative MRI study
- (2009) Gesa Ladewig et al. EXPERIMENTAL NEUROLOGY
- Evaluation of the PBR/TSPO Radioligand [18F]DPA-714 in a Rat Model of Focal Cerebral Ischemia
- (2009) Abraham Martín et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Neuroinflammation Extends Brain Tissue at Risk to Vital Peri-Infarct Tissue: A Double Tracer [11C]PK11195- and [18F]FDG-PET Study
- (2009) Michael Schroeter et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Two-photon laser scanning microscopy imaging of intact spinal cord and cerebral cortex reveals requirement for CXCR6 and neuroinflammation in immune cell infiltration of cortical injury sites
- (2009) Jiyun V. Kim et al. JOURNAL OF IMMUNOLOGICAL METHODS
- Distinct spatiotemporal pattern of CNS lesions revealed by USPIO-enhanced MRI in MOG-induced EAE rats implicates the involvement of spino-olivocerebellar pathways
- (2009) Chih-Liang Chin et al. JOURNAL OF NEUROIMMUNOLOGY
- The P2X7 Receptor Drives Microglial Activation and Proliferation: A Trophic Role for P2X7R Pore
- (2009) M. Monif et al. JOURNAL OF NEUROSCIENCE
- Radioisotopic Imaging of Neuroinflammation
- (2009) A. Winkeler et al. JOURNAL OF NUCLEAR MEDICINE
- 11C-PK11195 PET for the In Vivo Evaluation of Neuroinflammation in the Rat Brain After Cortical Spreading Depression
- (2009) Y. Cui et al. JOURNAL OF NUCLEAR MEDICINE
- Comparative Evaluation of the Translocator Protein Radioligands 11C-DPA-713, 18F-DPA-714, and 11C-PK11195 in a Rat Model of Acute Neuroinflammation
- (2009) F. Chauveau et al. JOURNAL OF NUCLEAR MEDICINE
- Neuroinflammation in Schizophrenia-Related Psychosis: A PET Study
- (2009) J. Doorduin et al. JOURNAL OF NUCLEAR MEDICINE
- Imipramine, in Part through Tumor Necrosis Factor Inhibition, Prevents Cognitive Decline and -Amyloid Accumulation in a Mouse Model of Alzheimer's Disease
- (2009) F. Chavant et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Methods to monitor gene therapy with molecular imaging
- (2009) Yannic Waerzeggers et al. METHODS
- [11C]-DPA-713 and [18F]-DPA-714 as New PET Tracers for TSPO: A Comparison with [11C]-(R)-PK11195 in a Rat Model of Herpes Encephalitis
- (2009) Janine Doorduin et al. MOLECULAR IMAGING AND BIOLOGY
- Does neuroinflammation fan the flame in neurodegenerative diseases?
- (2009) Tamy C Frank-Cannon et al. Molecular Neurodegeneration
- Minocycline 1-year therapy in multiple-system-atrophy: Effect on clinical symptoms and [11C](R)-PK11195 PET (MEMSA-trial)
- (2009) Richard Dodel et al. MOVEMENT DISORDERS
- Effector T cell interactions with meningeal vascular structures in nascent autoimmune CNS lesions
- (2009) Ingo Bartholomäus et al. NATURE
- A tissue-scale gradient of hydrogen peroxide mediates rapid wound detection in zebrafish
- (2009) Philipp Niethammer et al. NATURE
- T time in the brain
- (2009) Eng H Lo NATURE MEDICINE
- Pivotal role of cerebral interleukin-17–producing γδT cells in the delayed phase of ischemic brain injury
- (2009) Takashi Shichita et al. NATURE MEDICINE
- Regulatory T cells are key cerebroprotective immunomodulators in acute experimental stroke
- (2009) Arthur Liesz et al. NATURE MEDICINE
- Imaging outcomes for neuroprotection and repair in multiple sclerosis trials
- (2009) Frederik Barkhof et al. Nature Reviews Neurology
- Microglial activation and amyloid deposition in mild cognitive impairment: A PET study
- (2009) A. Okello et al. NEUROLOGY
- Taking Advantage of the Systemic Immune System to Cure Brain Diseases
- (2009) V. Wee Yong et al. NEURON
- Synthesis and biological evaluation of carbon-11- and fluorine-18-labeled 2-oxoquinoline derivatives for type 2 cannabinoid receptor positron emission tomography imaging
- (2009) Nele Evens et al. NUCLEAR MEDICINE AND BIOLOGY
- Evaluation of [11C]-DAA1106 for imaging and quantification of neuroinflammation in a rat model of herpes encephalitis
- (2009) Janine Doorduin et al. NUCLEAR MEDICINE AND BIOLOGY
- [11C]-PK11195 PET: Quantification of neuroinflammation and a monitor of anti-inflammatory treatment in Parkinson's disease?
- (2009) A.L. Bartels et al. PARKINSONISM & RELATED DISORDERS
- Microglial Involvement in Neuroplastic Changes Following Focal Brain Ischemia in Rats
- (2009) Alexandre Madinier et al. PLoS One
- Image-guided, noninvasive, spatiotemporal control of gene expression
- (2009) R. Deckers et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Temporal and Spatial Dynamics of Cerebral Immune Cell Accumulation in Stroke
- (2009) Mathias Gelderblom et al. STROKE
- Early-Stage Investigations of Ultrasmall Superparamagnetic Iron Oxide-Induced Signal Change After Permanent Middle Cerebral Artery Occlusion in Mice
- (2009) Virginie Desestret et al. STROKE
- Neuronal regulation of immune responses in the central nervous system
- (2009) Li Tian et al. TRENDS IN IMMUNOLOGY
- Longitudinal in Vivo Positron Emission Tomography Imaging of Infected and Activated Brain Macrophages in a Macaque Model of Human Immunodeficiency Virus Encephalitis Correlates with Central and Peripheral Markers of Encephalitis and Areas of Synaptic Degeneration
- (2008) Sriram Venneti et al. AMERICAN JOURNAL OF PATHOLOGY
- Pluriformity of inflammation in multiple sclerosis shown by ultra-small iron oxide particle enhancement
- (2008) Machteld M. Vellinga et al. BRAIN
- Myeloperoxidase-targeted imaging of active inflammatory lesions in murine experimental autoimmune encephalomyelitis
- (2008) J. W. Chen et al. BRAIN
- Debris clearance by microglia: an essential link between degeneration and regeneration
- (2008) H. Neumann et al. BRAIN
- Evaluation of CLINDE as potent translocator protein (18 kDa) SPECT radiotracer reflecting the degree of neuroinflammation in a rat model of microglial activation
- (2008) Nicolas Arlicot et al. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
- Nuclear imaging of neuroinflammation: a comprehensive review of [11C]PK11195 challengers
- (2008) Fabien Chauveau et al. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
- Bioluminescence in vivo imaging of autoimmune encephalomyelitis predicts disease
- (2008) Jian Luo et al. Journal of Neuroinflammation
- Novel Reference Region Model Reveals Increased Microglial and Reduced Vascular Binding of 11C-(R)-PK11195 in Patients with Alzheimer's Disease
- (2008) G. Tomasi et al. JOURNAL OF NUCLEAR MEDICINE
- DPA-714, a New Translocator Protein-Specific Ligand: Synthesis, Radiofluorination, and Pharmacologic Characterization
- (2008) M. L. James et al. JOURNAL OF NUCLEAR MEDICINE
- MRI in multiple sclerosis: current status and future prospects
- (2008) Rohit Bakshi et al. LANCET NEUROLOGY
- Origin and physiological roles of inflammation
- (2008) Ruslan Medzhitov NATURE
- PK11195 labels activated microglia in Alzheimer's disease and in vivo in a mouse model using PET
- (2008) Sriram Venneti et al. NEUROBIOLOGY OF AGING
- Microglia, amyloid, and cognition in Alzheimer's disease: An [11C](R)PK11195-PET and [11C]PIB-PET study
- (2008) Paul Edison et al. NEUROBIOLOGY OF DISEASE
- Non-invasive visualization of CNS inflammation with nuclear and optical imaging
- (2008) A. Wunder et al. NEUROSCIENCE
- Tracking the inflammatory response in stroke in vivo by sensing the enzyme myeloperoxidase
- (2008) M. O. Breckwoldt et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Live Imaging of Neuroinflammation Reveals Sex and Estrogen Effects on Astrocyte Response to Ischemic Injury
- (2008) Pierre Cordeau et al. STROKE
- Functional neuroimaging in multiple sclerosis with radiolabelled glia markers: Preliminary comparative PET studies with [11C]vinpocetine and [11C]PK11195 in patients
- (2007) Ádám Vas et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
- The high affinity peripheral benzodiazepine receptor ligand DAA1106 binds to activated and infected brain macrophages in areas of synaptic degeneration: Implications for PET imaging of neuroinflammation in lentiviral encephalitis
- (2007) Sriram Venneti et al. NEUROBIOLOGY OF DISEASE
- Evaluation of [11C]rofecoxib as PET tracer for cyclooxygenase 2 overexpression in rat models of inflammation
- (2007) Erik F.J. de Vries et al. NUCLEAR MEDICINE AND BIOLOGY
Become a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get StartedAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started