Second‐Coordination Sphere Effects on Selectivity and Specificity of Heme and Nonheme Iron Enzymes

A Promiscuous Cytochrome P450 Hydroxylates Aliphatic and Aromatic C-H Bonds of Aromatic 2,5-Diketopiperazines

(2019) Guangde Jiang et al.   CHEMBIOCHEM

Significance of protein-substrate hydrogen bonding for the selectivity of P450 catalysed oxidations

(2019) James Joseph De Voss et al.   CHEMISTRY-A EUROPEAN JOURNAL

An Alternative Active Site Architecture for O2 Activation in the Ergothioneine Biosynthetic EgtB from Chloracidobacterium thermophilum

(2019) Anja R. Stampfli et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A New Microbial Pathway for Organophosphonate Degradation Catalyzed by Two Previously Misannotated Non-Heme-Iron Oxygenases

(2019) Lauren J. Rajakovich et al.   BIOCHEMISTRY

Substrate Specificity in Thiol Dioxygenases

(2019) Sekotilani Aloi et al.   BIOCHEMISTRY

The Hydrogen Bond and Beyond: Perspectives for Rotational Investigations of Non‐Covalent Interactions

(2019) Marcos Juanes et al.   CHEMISTRY-A EUROPEAN JOURNAL

Experimental and theoretical studies of the porphyrin ligand effect on the electronic structure and reactivity of oxoiron(iv) porphyrin π-cation-radical complexes

(2019) Yuri Ishimizu et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Mechanistic Investigation of Oxygen Rebound in a Mononuclear Nonheme Iron Complex

(2019) Thomas M. Pangia et al.   INORGANIC CHEMISTRY

Flavonol biosynthesis by nonheme iron dioxygenases: A computational study into the structure and mechanism

(2019) Neelam Zeb et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Second-Coordination Sphere Effect on the Reactivity of Vanadium–Peroxo Complexes: A Computational Study

(2019) M. Qadri E. Mubarak et al.   INORGANIC CHEMISTRY

Selective Hydrogen Atom Abstraction from Dihydroflavonol by a Nonheme Iron Center Is the Key Step in the Enzymatic Flavonol Synthesis and Avoids Byproducts

(2019) Sidra Ghafoor et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Diverging Mechanisms: Cytochrome-P450-Catalyzed Demethylation and γ-Lactone Formation in Bacterial Gibberellin Biosynthesis

(2018) Raimund Nagel et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Structure and function of the cytochrome P450 peroxygenase enzymes

(2018) Andrew W. Munro et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Mechanistic Investigation of Oxidative Decarboxylation Catalyzed by Two Iron(II)- and 2-Oxoglutarate-Dependent Enzymes

(2018) Jhih-Liang Huang et al.   BIOCHEMISTRY

Protein Engineering of the Progesterone Hydroxylating P450-Monooxygenase CYP17A1 Alters its Regioselectivity

(2018) Lisa Morlock et al.   CHEMBIOCHEM

2-Oxoglutarate regulates binding of hydroxylated hypoxia-inducible factor to prolyl hydroxylase domain 2

(2018) Martine I. Abboud et al.   CHEMICAL COMMUNICATIONS

Mechanistic Insight on the Activity and Substrate Selectivity of Nonheme Iron Dioxygenases

(2018) Sam P. de Visser   CHEMICAL RECORD

On the Structure and Reaction Mechanism of Human Acireductone Dioxygenase

(2018) Anna Miłaczewska et al.   CHEMISTRY-A EUROPEAN JOURNAL

On how the binding cavity of AsqJ dioxygenase controls the desaturation reaction regioselectivity: a QM/MM study

(2018) Zuzanna Wojdyla et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Remote C–H Hydroxylation by an α-Ketoglutarate-Dependent Dioxygenase Enables Efficient Chemoenzymatic Synthesis of Manzacidin C and Proline Analogs

(2018) Christian R. Zwick et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enzymatic Cascade Reactions in Biosynthesis

(2018) Christopher T. Walsh et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Studies on the Substrate Selectivity of the Hypoxia-Inducible Factor Prolyl Hydroxylase 2 Catalytic Domain

(2018) Martine I. Abboud et al.   CHEMBIOCHEM

Structural and catalytic properties of the peroxygenase P450 enzyme CYP152K6 from Bacillus methanolicus

(2018) Hazel M. Girvan et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

A Comparative Review on the Catalytic Mechanism of Nonheme Iron Hydroxylases and Halogenases

(2018) Amy Timmins et al.   Catalysts

Elucidating the Reaction Pathway of Decarboxylation-Assisted Olefination Catalyzed by a Mononuclear Non-Heme Iron Enzyme

(2018) Cheng-Ping Yu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Mechanistic Studies of Fatty Acid Activation by CYP152 Peroxygenases Reveal Unexpected Desaturase Activity

(2018) Mathias Pickl et al.   ACS Catalysis

Mechanisms of Cytochrome P450-Catalyzed Oxidations

(2018) F. Peter Guengerich   ACS Catalysis

Does Substrate Positioning Affect the Selectivity and Reactivity in the Hectochlorin Biosynthesis Halogenase?

(2018) Amy Timmins et al.   Frontiers in Chemistry

Theoretical Study of the Mechanism of the Nonheme Iron Enzyme EgtB

(2017) Wen-Jie Wei et al.   INORGANIC CHEMISTRY

Catalytic Determinants of Alkene Production by the Cytochrome P450 Peroxygenase OleTJE

(2017) Sarah Matthews et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structures and Mechanisms of the Non-Heme Fe(II)- and 2-Oxoglutarate-Dependent Ethylene-Forming Enzyme: Substrate Binding Creates a Twist

(2017) Salette Martinez et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Sulfoxide Synthase versus Cysteine Dioxygenase Reactivity in a Nonheme Iron Enzyme

(2017) Abayomi S. Faponle et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Understanding How Prolyl-4-hydroxylase Structure Steers a Ferryl Oxidant toward Scission of a Strong C–H Bond

(2017) Amy Timmins et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structural and stereoelectronic insights into oxygenase-catalyzed formation of ethylene from 2-oxoglutarate

(2017) Zhihong Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biosynthesis of methyl-proline containing griselimycins, natural products with anti-tuberculosis activity

(2017) Peer Lukat et al.   Chemical Science

Harnessing non-covalent interactions to exert control over regioselectivity and site-selectivity in catalytic reactions

(2017) Holly J. Davis et al.   Chemical Science

Biochemical and Spectroscopic Characterization of the Non-Heme Fe(II)- and 2-Oxoglutarate-Dependent Ethylene-Forming Enzyme from Pseudomonas syringae pv. phaseolicola PK2

(2016) Salette Martinez et al.   BIOCHEMISTRY

Role of the Proximal Cysteine Hydrogen Bonding Interaction in Cytochrome P450 2B4 Studied by Cryoreduction, Electron Paramagnetic Resonance, and Electron–Nuclear Double Resonance Spectroscopy

(2016) Roman Davydov et al.   BIOCHEMISTRY

Enantioselective Benzylic Hydroxylation Catalysed by P450 Monooxygenases: Characterisation of a P450cam Mutant Library and Molecular Modelling

(2016) Anja Eichler et al.   CHEMBIOCHEM

Active Site Crowding of Cytochrome P450 3A4 as a Strategy To Alter Its Selectivity

(2016) Paolo Schiavini et al.   CHEMBIOCHEM

Intersection of the Roles of Cytochrome P450 Enzymes with Xenobiotic and Endogenous Substrates: Relevance to Toxicity and Drug Interactions

(2016) F. Peter Guengerich   CHEMICAL RESEARCH IN TOXICOLOGY

Origin of the Regioselective Fatty-Acid Hydroxylation versus Decarboxylation by a Cytochrome P450 Peroxygenase: What Drives the Reaction to Biofuel Production?

(2016) Abayomi S. Faponle et al.   CHEMISTRY-A EUROPEAN JOURNAL

Catalytic strategies of the non-heme iron dependent oxygenases and their roles in plant biology

(2016) Mark D White et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Is It Fe(III)-Oxyl Radical That Abstracts Hydrogen in the C–H Activation of TauD? A Theoretical Study Based on the DFT Potential Energy Surfaces

(2016) Binh Khanh Mai et al.   INORGANIC CHEMISTRY

Influence of cysteine 164 on active site structure in rat cysteine dioxygenase

(2016) Matthias Fellner et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Beyond ferryl-mediated hydroxylation: 40 years of the rebound mechanism and C–H activation

(2016) Xiongyi Huang et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Mechanism of O2 Activation by α-Ketoglutarate Dependent Oxygenases Revisited. A Quantum Chemical Study

(2016) Anna Wójcik et al.   JOURNAL OF PHYSICAL CHEMISTRY A

Reactivity of an FeIV-Oxo Complex with Protons and Oxidants

(2016) Ethan A. Hill et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Mechanistic Investigation of a Non-Heme Iron Enzyme Catalyzed Epoxidation in (−)-4′-Methoxycyclopenin Biosynthesis

(2016) Wei-chen Chang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Divergent non-heme iron enzymes in the nogalamycin biosynthetic pathway

(2016) Vilja Siitonen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Recent Structural Insights into Cytochrome P450 Function

(2016) F. Peter Guengerich et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Selective Chlorination of Substrates by the Halogenase SyrB2 Is Controlled by the Protein According to a Combined Quantum Mechanics/Molecular Mechanics and Molecular Dynamics Study

(2016) Jing Huang et al.   ACS Catalysis

Structure of the Sulfoxide Synthase EgtB from the Ergothioneine Biosynthetic Pathway

(2015) Kristina V. Goncharenko et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Oxidative Decarboxylation of Short-Chain Fatty Acids to 1-Alkenes

(2015) Alexander Dennig et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Active site diversification of P450cam with indole generates catalysts for benzylic oxidation reactions

(2015) Paul P Kelly et al.   Beilstein Journal of Organic Chemistry

Drug Metabolism by Cytochrome P450 Enzymes: What Distinguishes the Pathways Leading to Substrate Hydroxylation Over Desaturation?

(2015) Li Ji et al.   CHEMISTRY-A EUROPEAN JOURNAL

The Cysteine Dioxygenase Homologue fromPseudomonas aeruginosaIs a 3-Mercaptopropionate Dioxygenase

(2015) Egor P. Tchesnokov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Contributions of Ionic Interactions and Protein Dynamics to Cytochrome P450 2D6 (CYP2D6) Substrate and Inhibitor Binding

(2015) An Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Decarboxylation of Fatty Acids to Terminal Alkenes by Cytochrome P450 Compound I

(2015) Job L. Grant et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Endoperoxide formation by an α-ketoglutarate-dependent mononuclear non-haem iron enzyme

(2015) Wupeng Yan et al.   NATURE

Hydrogen peroxide-independent production of α-alkenes by OleTJE P450 fatty acid decarboxylase

(2014) Yi Liu et al.   Biotechnology for Biofuels

Ethylene-forming enzyme and bioethylene production

(2014) Carrie Eckert et al.   Biotechnology for Biofuels

More than just a Halogenase: Modification of Fatty Acyl Moieties by a Trifunctional Metal Enzyme

(2014) Sarah M. Pratter et al.   CHEMBIOCHEM

Heme Enzyme Structure and Function

(2014) Thomas L. Poulos   CHEMICAL REVIEWS

Quantum Chemical Studies of Mechanisms for Metalloenzymes

(2014) Margareta R. A. Blomberg et al.   CHEMICAL REVIEWS

Structure and Biochemical Properties of the Alkene Producing Cytochrome P450 OleTJE(CYP152L1) from theJeotgalicoccussp. 8456 Bacterium

(2014) James Belcher et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Role of Chloride in the Mechanism of O2 Activation at the Mononuclear Nonheme Fe(II) Center of the Halogenase HctB

(2014) Sarah M. Pratter et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Geometric and Electronic Structure Contributions to Function in Non-heme Iron Enzymes

(2013) Edward I. Solomon et al.   ACCOUNTS OF CHEMICAL RESEARCH

Differential Hydrogen Bonding in Human CYP17 Dictates Hydroxylation versus Lyase Chemistry

(2013) Michael Gregory et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Inversion of Enantioselectivity of a Mononuclear Non-Heme Iron(II)-dependent Hydroxylase by Tuning the Interplay of Metal-Center Geometry and Protein Structure

(2013) Sarah M. Pratter et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synergistic Effects of Mutations in Cytochrome P450cam Designed To Mimic CYP101D1

(2013) Dipanwita Batabyal et al.   BIOCHEMISTRY

Inverse Solvent Isotope Effects Arising from Substrate Triggering in the Factor Inhibiting Hypoxia Inducible Factor

(2013) John A. Hangasky et al.   BIOCHEMISTRY

Quantum Mechanics/Molecular Mechanics Study on the Oxygen Binding and Substrate Hydroxylation Step in AlkB Repair Enzymes

(2013) Matthew G. Quesne et al.   CHEMISTRY-A EUROPEAN JOURNAL

Resonance Raman and Electrocatalytic Behavior of Thiolate and Imidazole Bound Iron Porphyrin Complexes on Self Assembled Monolayers: Functional Modeling of Cytochrome P450

(2013) Kushal Sengupta et al.   INORGANIC CHEMISTRY

Substrate Placement Influences Reactivity in Non-heme Fe(II) Halogenases and Hydroxylases

(2013) Heather J. Kulik et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cysteine Dioxygenase Structures from pH4 to 9: Consistent Cys-Persulfenate Formation at Intermediate pH and a Cys-Bound Enzyme at Higher pH

(2013) Camden M. Driggers et al.   JOURNAL OF MOLECULAR BIOLOGY

Mechanistic Insights on the ortho-Hydroxylation of Aromatic Compounds by Non-heme Iron Complex: A Computational Case Study on the Comparative Oxidative Ability of Ferric-Hydroperoxo and High-Valent FeIV═O and FeV═O Intermediates

(2013) Azaj Ansari et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Secondary Coordination Sphere Influence on the Reactivity of Nonheme Iron(II) Complexes: An Experimental and DFT Approach

(2013) Sumit Sahu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Experimental Documentation of the Structural Consequences of Hydrogen-Bonding Interactions to the Proximal Cysteine of a Cytochrome P450

(2012) Piotr J. Mak et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Mechanism of Benzylic Hydroxylation by 4-Hydroxymandelate Synthase. A Computational Study

(2012) Anna Wójcik et al.   BIOCHEMISTRY

Inverse Solvent Isotope Effects Demonstrate Slow Aquo Release from Hypoxia Inducible Factor-Prolyl Hydroxylase (PHD2)

(2012) Shannon C. Flagg et al.   BIOCHEMISTRY

Structure and function of atypically coordinated enzymatic mononuclear non-heme-Fe(II) centers

(2012) Daniela Buongiorno et al.   COORDINATION CHEMISTRY REVIEWS

Understanding the mechanism of cytochrome P450 3A4: recent advances and remaining problems

(2012) Irina F. Sevrioukova et al.   DALTON TRANSACTIONS

Model Iron–Oxo Species and the Oxidation of Imidazole: Insights into the Mechanism of OvoA and EgtB?

(2012) Eric A. C. Bushnell et al.   INORGANIC CHEMISTRY

Regioselectivity of substrate hydroxylation versus halogenation by a nonheme iron(IV)–oxo complex: possibility of rearrangement pathways

(2012) Matthew G. Quesne et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

The biology and chemistry of high-valent iron–oxo and iron–nitrido complexes

(2012) Johannes Hohenberger et al.   Nature Communications

Terminal Olefin (1-Alkene) Biosynthesis by a Novel P450 Fatty Acid Decarboxylase fromJeotgalicoccusSpecies

(2011) Mathew A. Rude et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Requirements for Skp1 Processing by Cytosolic Prolyl 4(trans)-Hydroxylase and α-N-Acetylglucosaminyltransferase Enzymes Involved in O2Signaling inDictyostelium

(2011) Hanke van der Wel et al.   BIOCHEMISTRY

Effect of the Axial Ligand on Substrate Sulfoxidation Mediated by Iron(IV)-Oxo Porphyrin Cation Radical Oxidants

(2011) Devesh Kumar et al.   CHEMISTRY-A EUROPEAN JOURNAL

Perferryl FeV–Oxo Nonheme Complexes: Do They Have High-Spin or Low-Spin Ground States?

(2011) Hui Chen et al.   Journal of Chemical Theory and Computation

DFT and Ab Initio Study of Iron-Oxo Porphyrins: May They Have a Low-Lying Iron(V)-Oxo Electromer?

(2011) Mariusz Radoń et al.   Journal of Chemical Theory and Computation

Theoretical Study on the Mechanism of the Oxygen Activation Process in Cysteine Dioxygenase Enzymes

(2011) Devesh Kumar et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Unprecedented Peroxidase-like Activity ofRhodnius prolixusNitrophorin 2: Identification of the [FeIV═O Por•]+and [FeIV═O Por](Tyr38•) Intermediates and Their Role(s) in Substrate Oxidation

(2010) Rahul Singh et al.   BIOCHEMISTRY

Prolyl 4-hydroxylase

(2010) Kelly L. Gorres et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Molecular Characterization of a Class I P450 Electron Transfer System fromNovosphingobium aromaticivoransDSM12444

(2010) Wen Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Steric Factors Override Thermodynamic Driving Force in Regioselectivity of Proline Hydroxylation by Prolyl-4-hydroxylase Enzymes

(2010) Baharan Karamzadeh et al.   JOURNAL OF PHYSICAL CHEMISTRY A

A Remarkably Bent Diiron(III)-μ-Hydroxo Bisporphyrin: Unusual Stabilization of Two Spin States of Iron in a Single Molecular Framework

(2010) Sudip Kumar Ghosh et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Mechanism of Selective Halogenation by SyrB2: A Computational Study

(2010) Tomasz Borowski et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cytochrome P450 Compound I: Capture, Characterization, and C-H Bond Activation Kinetics

(2010) J. Rittle et al.   SCIENCE

A Non-Heme Iron-Mediated Chemical Demethylation in DNA and RNA

(2009) Chengqi Yi et al.   ACCOUNTS OF CHEMICAL RESEARCH

Substrate-Triggered Formation and Remarkable Stability of the C−H Bond-Cleaving Chloroferryl Intermediate in the Aliphatic Halogenase, SyrB2

(2009) Megan L. Matthews et al.   BIOCHEMISTRY

Origin of the Correlation of the Rate Constant of Substrate Hydroxylation by Nonheme Iron(IV)-oxo Complexes with the Bond-Dissociation Energy of the CH Bond of the Substrate

(2009) Reza Latifi et al.   CHEMISTRY-A EUROPEAN JOURNAL

Why does the enzyme SyrB2 chlorinate, but does not hydroxylate, saturated hydrocarbons? A density functional theory (DFT) study

(2009) Shanthi Pandian et al.   DALTON TRANSACTIONS

The Crystal Structure of an Algal Prolyl 4-Hydroxylase Complexed with a Proline-rich Peptide Reveals a Novel Buried Tripeptide Binding Motif

(2009) M. Kristian Koski et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Effect of Porphyrin Ligands on the Regioselective Dehydrogenation versus Epoxidation of Olefins by Oxoiron(IV) Mimics of Cytochrome P450

(2009) Devesh Kumar et al.   JOURNAL OF PHYSICAL CHEMISTRY A

Compound I Reactivity Defines Alkene Oxidation Selectivity in Cytochrome P450cam

(2009) Richard Lonsdale et al.   JOURNAL OF PHYSICAL CHEMISTRY B

First-Principles Study of Non-heme Fe(II) Halogenase SyrB2 Reactivity

(2009) Heather J. Kulik et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The Molecular Mechanism of the Catalase Reaction

(2009) Mercedes Alfonso-Prieto et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Trends in Substrate Hydroxylation Reactions by Heme and Nonheme Iron(IV)-Oxo Oxidants Give Correlations between Intrinsic Properties of the Oxidant with Barrier Height

(2009) Sam P. de Visser   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Mechanistic considerations of halogenating enzymes

(2009) Alison Butler et al.   NATURE

Mononuclear non-heme iron enzymes with the 2-His-1-carboxylate facial triad: recent developments in enzymology and modeling studies

(2008) Pieter C. A. Bruijnincx et al.   CHEMICAL SOCIETY REVIEWS

Non-heme iron-dependent dioxygenases: unravelling catalytic mechanisms for complex enzymatic oxidations

(2008) Timothy DH Bugg et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Comparative Quantum Mechanics/Molecular Mechanics (QM/MM) and Density Functional Theory Calculations on the Oxo−Iron Species of Taurine/α-Ketoglutarate Dioxygenase

(2008) Elizabeth Godfrey et al.   JOURNAL OF PHYSICAL CHEMISTRY A

Carbon Dioxide: A Waste Product in the Catalytic Cycle of α-Ketoglutarate Dependent Halogenases Prevents the Formation of Hydroxylated By-Products

(2008) Sam P. de Visser et al.   JOURNAL OF PHYSICAL CHEMISTRY B

A Valence Bond Modeling of Trends in Hydrogen Abstraction Barriers and Transition States of Hydroxylation Reactions Catalyzed by Cytochrome P450 Enzymes

(2008) Sason Shaik et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Versatility of biological non-heme Fe(II) centers in oxygen activation reactions

(2008) Elena G Kovaleva et al.   Nature Chemical Biology

Significance of Prolyl Hydroxylase 2 in the Interference of Aryl Hydrocarbon Receptor and Hypoxia-Inducible Factor-1α Signaling

(2007) Anja Seifert et al.   CHEMICAL RESEARCH IN TOXICOLOGY