Inversion of Enantioselectivity of a Mononuclear Non-Heme Iron(II)-dependent Hydroxylase by Tuning the Interplay of Metal-Center Geometry and Protein Structure

Achieving Regio- and Enantioselectivity of P450-Catalyzed Oxidative CH Activation of Small Functionalized Molecules by Structure-Guided Directed Evolution

(2012) Rubén Agudo et al.   CHEMBIOCHEM

Evolving P450pyr hydroxylase for highly enantioselective hydroxylation at non-activated carbon atom

(2012) Son Quang Pham et al.   CHEMICAL COMMUNICATIONS

Evidence for the Mechanism of Hydroxylation by 4-Hydroxyphenylpyruvate Dioxygenase and Hydroxymandelate Synthase from Intermediate Partitioning in Active Site Variants

(2011) Dhara D. Shah et al.   BIOCHEMISTRY

Chemistry: It's not easy being green

(2011) Katharine Sanderson   NATURE

Regio- and stereoselectivity of P450-catalysed hydroxylation of steroids controlled by laboratory evolution

(2011) Sabrina Kille et al.   Nature Chemistry

Cytochrome P450 monooxygenases: an update on perspectives for synthetic application

(2011) Vlada B. Urlacher et al.   TRENDS IN BIOTECHNOLOGY

Product Analysis and Inhibition Studies of a Causative Asn to Ser Variant of 4-Hydroxyphenylpyruvate Dioxygenase Suggest a Simple Route to the Treatment of Hawkinsinuria

(2010) June M. Brownlee et al.   BIOCHEMISTRY

Inverting the enantioselectivity of P450pyr monooxygenase by directed evolution

(2010) Weng Lin Tang et al.   CHEMICAL COMMUNICATIONS

Two Roads Diverged:  The Structure of Hydroxymandelate Synthase fromAmycolatopsis orientalisin Complex with 4-Hydroxymandelate†,‡

(2008) June Brownlee et al.   BIOCHEMISTRY

Versatility of biological non-heme Fe(II) centers in oxygen activation reactions

(2008) Elena G Kovaleva et al.   Nature Chemical Biology