CD147 deficiency in T cells prevents thymic involution by inhibiting the EMT process in TECs in the presence of TGFβ

ACPAs promote IL-1β production in rheumatoid arthritis by activating the NLRP3 inflammasome

(2019) Xiwen Dong et al.   Cellular & Molecular Immunology

The Role of the Thymus in the Immune Response

(2019) Puspa Thapa et al.   Thoracic Surgery Clinics

Disrupting CD147-RAP2 interaction abrogates erythrocyte invasion byPlasmodium falciparum

(2018) Meng-Yao Zhang et al.   BLOOD

A critical epitope in CD147 facilitates memory CD4+ T-cell hyper-activation in rheumatoid arthritis

(2018) Na Guo et al.   Cellular & Molecular Immunology

Basolateral CD147 induces hepatocyte polarity loss by E-cadherin ubiquitination and degradation in hepatocellular carcinoma progress

(2018) Meng Lu et al.   HEPATOLOGY

Tumor-Associated Macrophages Derived TGF-β‒Induced Epithelial to Mesenchymal Transition in Colorectal Cancer Cells through Smad2,3-4/Snail Signaling Pathway

(2018) Jianhui Cai et al.   Cancer Research and Treatment

Annexin A2 overexpression associates with colorectal cancer invasiveness and TGF-ß induced epithelial mesenchymal transition via Src/ANXA2/STAT3

(2018) Murilo R. Rocha et al.   Scientific Reports

PPARgamma Deficiency Counteracts Thymic Senescence

(2017) David Ernszt et al.   Frontiers in Immunology

Targeting CD147 for T to NK Lineage Reprogramming and Tumor Therapy

(2017) Jie-Jie Geng et al.   EBioMedicine

Thymic homing of activated CD4+ T cells induces degeneration of the thymic epithelium through excessive RANK signaling

(2017) Chen Yin et al.   Scientific Reports

Molecular association of CD98, CD29, and CD147 critically mediates monocytic U937 cell adhesion

(2016) Mi-Yeon Kim et al.   KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY

EMMPRIN, an upstream regulator of MMPs, in CNS biology

(2015) Deepak Kumar Kaushik et al.   MATRIX BIOLOGY

HAb18G/CD147 is involved in TGF-β-induced epithelial-mesenchymal transition and hepatocellular carcinoma invasion

(2014) Ning-Yu Ru et al.   CELL BIOLOGY INTERNATIONAL

A chimeric antibody targeting CD147 inhibits hepatocellular carcinoma cell motility via FAK-PI3K-Akt-Girdin signaling pathway

(2014) Yuan Wang et al.   CLINICAL & EXPERIMENTAL METASTASIS

Important Functional Roles of Basigin in Thymocyte Development and T cell Activation

(2014) Hui Yao et al.   International Journal of Biological Sciences

The Biological Function and Clinical Utilization of CD147 in Human Diseases: A Review of the Current Scientific Literature

(2014) Lijuan Xiong et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

A regulatory role for TGF-β signaling in the establishment and function of the thymic medulla

(2014) Mathias Hauri-Hohl et al.   NATURE IMMUNOLOGY

Overexpressed FOXC2 in ovarian cancer enhances the epithelial-to-mesenchymal transition and invasion of ovarian cancer cells

(2014) BO LIU et al.   ONCOLOGY REPORTS

Novel regulators of spermatogenesis

(2014) Kin Lam Fok et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

CD147 in Cardiovascular Disease and Thrombosis

(2014) Leonard Kritharides et al.   SEMINARS IN THROMBOSIS AND HEMOSTASIS

Thymic rejuvenation and aging

(2013) Melissa S Ventevogel et al.   CURRENT OPINION IN IMMUNOLOGY

TGF-β type II receptor expression in thymic epithelial cells inhibits the development of Hassall’s corpuscles in mice

(2013) Chikako Odaka et al.   INTERNATIONAL IMMUNOLOGY

Inactivation of the RB family prevents thymus involution and promotes thymic function by direct control of Foxn1 expression

(2013) Phillip M. Garfin et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Changes in primary lymphoid organs with aging

(2012) Ivan K. Chinn et al.   SEMINARS IN IMMUNOLOGY

Thymic epithelial cells: working class heroes for T cell development and repertoire selection

(2012) Graham Anderson et al.   TRENDS IN IMMUNOLOGY

Structure and function of the thymic microenvironment

(2011) Nancy Ruth Manley   Frontiers in Bioscience-Landmark

HAb18G/CD147 promotes cell motility by regulating annexin II-activated RhoA and Rac1 signaling pathways in hepatocellular carcinoma cells

(2011) Pu Zhao et al.   HEPATOLOGY

HAb18G/CD147 promotes epithelial–mesenchymal transition through TGF-β signaling and is transcriptionally regulated by Slug

(2011) J Wu et al.   ONCOGENE

Involvement of HAb18G/CD147 in T cell activation and immunological synapse formation

(2010) Jinsong Hu et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Decision checkpoints in the thymus

(2010) Andrea C Carpenter et al.   NATURE IMMUNOLOGY

Wnt4 and LAP2alpha as Pacemakers of Thymic Epithelial Senescence

(2010) Krisztian Kvell et al.   PLoS One

FOXC2 controls formation and maturation of lymphatic collecting vessels through cooperation with NFATc1

(2009) Camilla Norrmén et al.   JOURNAL OF CELL BIOLOGY

Inhibition of Thymic Adipogenesis by Caloric Restriction Is Coupled with Reduction in Age-Related Thymic Involution

(2009) H. Yang et al.   JOURNAL OF IMMUNOLOGY

Thymic involution and immune reconstitution

(2009) Heather E. Lynch et al.   TRENDS IN IMMUNOLOGY

Thymus Organogenesis

(2008) Hans-Reimer Rodewald   Annual Review of Immunology

TGF-  signaling in thymic epithelial cells regulates thymic involution and postirradiation reconstitution

(2008) M. M. Hauri-Hohl et al.   BLOOD

Thymus development and function

(2008) Thomas Boehm   CURRENT OPINION IN IMMUNOLOGY

Deficient Ghrelin Receptor-mediated Signaling Compromises Thymic Stromal Cell Microenvironment by Accelerating Thymic Adiposity

(2008) Yun-Hee Youm et al.   JOURNAL OF BIOLOGICAL CHEMISTRY