The antimetastatic activity of orlistat is accompanied by an antitumoral immune response in mouse melanoma
出版年份 2019 全文链接
标题
The antimetastatic activity of orlistat is accompanied by an antitumoral immune response in mouse melanoma
作者
关键词
-
出版物
CANCER CHEMOTHERAPY AND PHARMACOLOGY
Volume 85, Issue 2, Pages 321-330
出版商
Springer Science and Business Media LLC
发表日期
2019-12-20
DOI
10.1007/s00280-019-04010-1
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- An unexpected link between fatty acid synthase and cholesterol synthesis in proinflammatory macrophage activation
- (2018) Richard G. Carroll et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Targeted agents and immunotherapies: optimizing outcomes in melanoma
- (2017) Jason J. Luke et al. Nature Reviews Clinical Oncology
- FASN Inhibition and Taxane Treatment Combine to Enhance Anti-tumor Efficacy in Diverse Xenograft Tumor Models through Disruption of Tubulin Palmitoylation and Microtubule Organization and FASN Inhibition-Mediated Effects on Oncogenic Signaling and Gene Expression
- (2017) Timothy S. Heuer et al. EBioMedicine
- Effects of fatty acid synthase inhibitors on lymphatic vessels: an in vitro and in vivo study in a melanoma model
- (2016) Débora C Bastos et al. LABORATORY INVESTIGATION
- Potentiating the antitumour response of CD8+ T cells by modulating cholesterol metabolism
- (2016) Wei Yang et al. NATURE
- Inhibition of de novo Palmitate Synthesis by Fatty Acid Synthase Induces Apoptosis in Tumor Cells by Remodeling Cell Membranes, Inhibiting Signaling Pathways, and Reprogramming Gene Expression
- (2015) Richard Ventura et al. EBioMedicine
- IL-12 Produced by Dendritic Cells Augments CD8+ T Cell Activation through the Production of the Chemokines CCL1 and CCL17
- (2014) C. J. Henry et al. JOURNAL OF IMMUNOLOGY
- Role of Fatty-Acid Synthesis in Dendritic Cell Generation and Function
- (2013) A. Rehman et al. JOURNAL OF IMMUNOLOGY
- CD81 Controls Sustained T Cell Activation Signaling and Defines the Maturation Stages of Cognate Immunological Synapses
- (2013) V. Rocha-Perugini et al. MOLECULAR AND CELLULAR BIOLOGY
- The Fatty Acid Synthase Inhibitor Orlistat Reduces the Growth and Metastasis of Orthotopic Tongue Oral Squamous Cell Carcinomas
- (2013) M. Agostini et al. MOLECULAR CANCER THERAPEUTICS
- Therapy for metastatic melanoma: the past, present, and future
- (2012) Laura Finn et al. BMC Medicine
- The fatty acid synthase inhibitor orlistat reduces experimental metastases and angiogenesis in B16-F10 melanomas
- (2012) F Seguin et al. BRITISH JOURNAL OF CANCER
- Immunotype and Immunohistologic Characteristics of Tumor-Infiltrating Immune Cells Are Associated with Clinical Outcome in Metastatic Melanoma
- (2012) G. Erdag et al. CANCER RESEARCH
- Local changes in lipid environment of TCR microclusters regulate membrane binding by the CD3ε cytoplasmic domain
- (2012) Etienne Gagnon et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Elevated lipogenesis in epithelial stem-like cell confers survival advantage in ductal carcinoma in situ of breast cancer
- (2012) P R Pandey et al. ONCOGENE
- Imidazopyridine-Based Fatty Acid Synthase Inhibitors That Show Anti-HCV Activity and in Vivo Target Modulation
- (2012) Johan D. Oslob et al. ACS Medicinal Chemistry Letters
- Selective BRAF Inhibitors Induce Marked T-cell Infiltration into Human Metastatic Melanoma
- (2011) James S. Wilmott et al. CLINICAL CANCER RESEARCH
- Systematic Review of Medical Treatment in Melanoma: Current Status and Future Prospects
- (2011) C. Garbe et al. ONCOLOGIST
- Expression of fatty acid synthase (FASN) in oral nevi and melanoma
- (2011) BAB de Andrade et al. ORAL DISEASES
- Visualizing inhibition of fatty acid synthase through mass spectrometric analysis of mitochondria from melanoma cells
- (2011) Karina G. Zecchin et al. RAPID COMMUNICATIONS IN MASS SPECTROMETRY
- Cancer resistance of SR/CR mice in the genetic knockout backgrounds of leukocyte effector mechanisms: determinations for functional requirements
- (2010) Anne M Sanders et al. BMC CANCER
- Dacarbazine Treatment before Peptide Vaccination Enlarges T-Cell Repertoire Diversity of Melan-A-Specific, Tumor-Reactive CTL in Melanoma Patients
- (2010) B. Palermo et al. CANCER RESEARCH
- The paradox of tumor-associated neutrophils: Fueling tumor growth with cytotoxic substances
- (2010) A. McGarry Houghton CELL CYCLE
- Chemotherapy enhances tumor cell susceptibility to CTL-mediated killing during cancer immunotherapy in mice
- (2010) Rupal Ramakrishnan et al. JOURNAL OF CLINICAL INVESTIGATION
- Inhibition of fatty acid synthase in melanoma cells activates the intrinsic pathway of apoptosis
- (2010) Karina G Zecchin et al. LABORATORY INVESTIGATION
- Fatty Acid Synthase: A Metabolic Enzyme and Candidate Oncogene in Prostate Cancer
- (2009) Toshiro Migita et al. JNCI-Journal of the National Cancer Institute
- Chemomodulation of human dendritic cell function by antineoplastic agents in low noncytotoxic concentrations
- (2009) Ramon Kaneno et al. Journal of Translational Medicine
- Fatty acid synthase is up-regulated during hepatitis C virus infection and regulates hepatitis C virus entry and production
- (2008) Wei Yang et al. HEPATOLOGY
- Fatty acid synthase inhibition with Orlistat promotes apoptosis and reduces cell growth and lymph node metastasis in a mouse melanoma model
- (2008) Marco A. Carvalho et al. INTERNATIONAL JOURNAL OF CANCER
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExplorePublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More