Local changes in lipid environment of TCR microclusters regulate membrane binding by the CD3ε cytoplasmic domain

Self-reactive human CD4 T cell clones form unusual immunological synapses

(2012) David A. Schubert et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Phosphatidylserine dynamics in cellular membranes

(2012) Jason G. Kay et al.   MOLECULAR BIOLOGY OF THE CELL

High-resolution mapping reveals topologically distinct cellular pools of phosphatidylserine

(2011) Gregory D. Fairn et al.   JOURNAL OF CELL BIOLOGY

The CD3   Subunit Contains a Phosphoinositide-Binding Motif That Is Required for the Stable Accumulation of TCR-CD3 Complex at the Immunological Synapse

(2011) L. M. DeFord-Watts et al.   JOURNAL OF IMMUNOLOGY

Investigating protein-protein interactions in living cells using fluorescence lifetime imaging microscopy

(2011) Yuansheng Sun et al.   Nature Protocols

Phosphatidylinositol (4,5) Bisphosphate Controls T Cell Activation by Regulating T Cell Rigidity and Organization

(2011) Yi Sun et al.   PLoS One

Basic residues in the T-cell receptor   cytoplasmic domain mediate membrane association and modulate signaling

(2011) H. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Essential Role of Ubiquitin and TSG101 Protein in Formation and Function of the Central Supramolecular Activation Cluster

(2010) Santosha Vardhana et al.   IMMUNITY

T-Cell Receptor Microclusters Critical for T-Cell Activation Are Formed Independently of Lipid Raft Clustering

(2010) A. Hashimoto-Tane et al.   MOLECULAR AND CELLULAR BIOLOGY

Calcium-dependent phospholipid scrambling by TMEM16F

(2010) Jun Suzuki et al.   NATURE

The kinetics of two-dimensional TCR and pMHC interactions determine T-cell responsiveness

(2010) Jun Huang et al.   NATURE

TCR–peptide–MHC interactions in situ show accelerated kinetics and increased affinity

(2010) Johannes B. Huppa et al.   NATURE

Coordination of Receptor Signaling in Multiple Hematopoietic Cell Lineages by the Adaptor Protein SLP-76

(2010) M. S. Jordan et al.   Cold Spring Harbor Perspectives in Biology

The LAT Story: A Tale of Cooperativity, Coordination, and Choreography

(2010) L. Balagopalan et al.   Cold Spring Harbor Perspectives in Biology

ZAP-70: An Essential Kinase in T-cell Signaling

(2010) H. Wang et al.   Cold Spring Harbor Perspectives in Biology

P4 ATPases - Lipid flippases and their role in disease

(2009) Dineke E. Folmer et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Quantitative Comparison of Different Fluorescent Protein Couples for Fast FRET-FLIM Acquisition

(2009) Sergi Padilla-Parra et al.   BIOPHYSICAL JOURNAL

Phosphoinositide 3-kinase-regulated adapters in lymphocyte activation

(2009) Ting-ting Zhang et al.   IMMUNOLOGICAL REVIEWS

Phosphatidylserine decarboxylases, key enzymes of lipid metabolism

(2009) Irmgard Schuiki et al.   IUBMB LIFE

Contribution of phosphatidylserine to membrane surface charge and protein targeting during phagosome maturation

(2009) Tony Yeung et al.   JOURNAL OF CELL BIOLOGY

In Vivo Enhancement of Peptide Display by MHC Class II Molecules with Small Molecule Catalysts of Peptide Exchange

(2009) Melissa J. Call et al.   JOURNAL OF IMMUNOLOGY

The Cytoplasmic Tail of the T Cell Receptor CD3   Subunit Contains a Phospholipid-Binding Motif that Regulates T Cell Functions

(2009) L. M. DeFord-Watts et al.   JOURNAL OF IMMUNOLOGY

Regulation of T Cell Receptor Activation by Dynamic Membrane Binding of the CD3ɛ Cytoplasmic Tyrosine-Based Motif

(2008) Chenqi Xu et al.   CELL

Membrane Phosphatidylserine Regulates Surface Charge and Protein Localization

(2008) T. Yeung et al.   SCIENCE