Online control of cell culture redox potential prevents antibody interchain disulfide bond reduction
出版年份 2020 全文链接
标题
Online control of cell culture redox potential prevents antibody interchain disulfide bond reduction
作者
关键词
-
出版物
BIOTECHNOLOGY AND BIOENGINEERING
Volume -, Issue -, Pages -
出版商
Wiley
发表日期
2020-01-20
DOI
10.1002/bit.27281
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Fc Sialylation Prolongs Serum Half-Life of Therapeutic Antibodies
- (2019) Mathilde Bas et al. JOURNAL OF IMMUNOLOGY
- Impact of depth filtration on disulfide bond reduction during downstream processing of monoclonal antibodies from CHO cell cultures
- (2019) Brian O'Mara et al. BIOTECHNOLOGY AND BIOENGINEERING
- Intracellular response of CHO cells to oxidative stress and its influence on metabolism and antibody production
- (2018) Michael W. Handlogten et al. BIOCHEMICAL ENGINEERING JOURNAL
- Antibodies to watch in 2018
- (2018) Hélène Kaplon et al. mAbs
- Characterization and analysis of scFv-IgG bispecific antibody size variants
- (2018) Mingyan Cao et al. mAbs
- Optimization of a micro-scale, high throughput process development tool and the demonstration of comparable process performance and product quality with biopharmaceutical manufacturing processes
- (2017) Steven T. Evans et al. JOURNAL OF CHROMATOGRAPHY A
- Glycation of antibodies: Modification, methods and potential effects on biological functions
- (2017) Bingchuan Wei et al. mAbs
- The making of bispecific antibodies
- (2017) Ulrich Brinkmann et al. mAbs
- Protein asparagine deamidation prediction based on structures with machine learning methods
- (2017) Lei Jia et al. PLoS One
- An automated laboratory-scale methodology for the generation of sheared mammalian cell culture samples
- (2017) Adrian Joseph et al. Biotechnology Journal
- Cell culture media impact on drug product solution stability
- (2016) Jennifer L. Purdie et al. BIOTECHNOLOGY PROGRESS
- The basics of thiols and cysteines in redox biology and chemistry
- (2015) Leslie B. Poole FREE RADICAL BIOLOGY AND MEDICINE
- Investigation of antibody disulfide reduction and re-oxidation and impact to biological activities
- (2015) Tian Wang et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
- Air sparging for prevention of antibody disulfide bond reduction in harvested CHO cell culture fluid
- (2014) Melissa Mun et al. BIOTECHNOLOGY AND BIOENGINEERING
- Monoclonal antibody disulfide reduction during manufacturing
- (2013) Katariina M. Hutterer et al. mAbs
- Control of redox potential in hybridoma cultures: effects on MAb production, metabolism, and apoptosis
- (2012) Angélica Meneses-Acosta et al. JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY
- High-mannose glycans on the Fc region of therapeutic IgG antibodies increase serum clearance in humans
- (2011) A. M. Goetze et al. GLYCOBIOLOGY
- Identification and prevention of antibody disulfide bond reduction during cell culture manufacturing
- (2010) Melody Trexler-Schmidt et al. BIOTECHNOLOGY AND BIOENGINEERING
- Mechanism of antibody reduction in cell culture production processes
- (2010) Yung-Hsiang Kao et al. BIOTECHNOLOGY AND BIOENGINEERING
- Cell culture processes for monoclonal antibody production
- (2010) Feng Li et al. mAbs
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