Thymoquinone as a Potential Neuroprotector in Acute and Chronic Forms of Cerebral Pathology

Neuroprotective Effects of Thymoquinone in Acrylamide-Induced Peripheral Nervous System Toxicity Through MAPKinase and Apoptosis Pathways in Rat

(2019) Jamshid Tabeshpour et al.   NEUROCHEMICAL RESEARCH

Thymoquinone therapy remediates elevated brain tissue inflammatory mediators induced by chronic administration of food preservatives

(2019) Ahmed Mohsen Hamdan et al.   Scientific Reports

SkQThy, a novel and promising mitochondria-targeted antioxidant

(2019) T.N. Goleva et al.   MITOCHONDRION

Thymoquinone prevents neurodegeneration against MPTP in vivo and modulates α-synuclein aggregation in vitro

(2019) Mustafa T. Ardah et al.   NEUROCHEMISTRY INTERNATIONAL

Thymoquinone alleviates arsenic induced hippocampal toxicity and mitochondrial dysfunction by modulating mPTP in Wistar rats

(2018) Fakiha Firdaus et al.   BIOMEDICINE & PHARMACOTHERAPY

Thymoquinone activates MAPK pathway in hippocampus of streptozotocin-treated rat model

(2018) Tugce Dalli et al.   BIOMEDICINE & PHARMACOTHERAPY

A Review on Possible Therapeutic Effect of Nigella sativa and Thymoquinone in Neurodegenerative Diseases

(2018) Saeed Samarghndian et al.   CNS & Neurological Disorders-Drug Targets

The Neuroprotective Effects of Thymoquinone: A Review

(2018) Tahereh Farkhondeh et al.   Dose-Response

Thymoquinone loaded solid lipid nanoparticles counteracts 3-Nitropropionic acid induced motor impairments and neuroinflammation in rat model of Huntington’s disease

(2018) Surekha Ramachandran et al.   METABOLIC BRAIN DISEASE

Neuropharmacological Potential and Delivery Prospects of Thymoquinone for Neurological Disorders

(2018) Md. Jakaria et al.   Oxidative Medicine and Cellular Longevity

Dissecting the Potential Roles of Nigella sativa and Its Constituent Thymoquinone on the Prevention and on the Progression of Alzheimer's Disease

(2018) Marco Cascella et al.   Frontiers in Aging Neuroscience

Thymoquinone inhibits the metastasis of RCC cells by inducing autophagy via AMPK/mTOR signaling pathway

(2018) Yujiao Zhang et al.   CANCER SCIENCE

Evaluation of phyto-medicinal efficacy of thymoquinone against Arsenic induced mitochondrial dysfunction and cytotoxicity in SH-SY5Y cells

(2018) Fakiha Firdaus et al.   PHYTOMEDICINE

Thymoquinone exerts neuroprotective effect in animal model of Parkinson’s disease

(2017) Seyedeh Shohreh Ebrahimi et al.   TOXICOLOGY LETTERS

Therapeutic Potential and Pharmaceutical Development of Thymoquinone: A Multitargeted Molecule of Natural Origin

(2017) Sameer N. Goyal et al.   Frontiers in Pharmacology

Cardiolipin in Central Nervous System Physiology and Pathology

(2016) Caitlin B. Pointer et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

The Role ofNigella sativaand Its Active Constituents in Learning and Memory

(2016) Mohamad Khairul Azali Sahak et al.   Evidence-based Complementary and Alternative Medicine

Quantification and evaluation of thymoquinone loaded mucoadhesive nanoemulsion for treatment of cerebral ischemia

(2016) Niyaz Ahmad et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Preclinical and clinical effects of Nigella sativa and its constituent, thymoquinone: A review

(2016) Zahra Gholamnezhad et al.   JOURNAL OF ETHNOPHARMACOLOGY

Neuroprotective effects of thymoquinone against spinal cord ischemia-reperfusion injury by attenuation of inflammation, oxidative stress, and apoptosis

(2016) Emre Cemal Gökce et al.   JOURNAL OF NEUROSURGERY-SPINE

Neuroprotective properties of mitochondria-targeted antioxidants of the SkQ-type

(2016) Nickolay K. Isaev et al.   REVIEWS IN THE NEUROSCIENCES

Traumatic brain injury: a risk factor for neurodegenerative diseases

(2016) Rajaneesh Gupta et al.   REVIEWS IN THE NEUROSCIENCES

Neuroprotective Effects of Thymoquinone on the Hippocampus in a Rat Model of Traumatic Brain Injury

(2016) İsmail Gülşen et al.   World Neurosurgery

Anti-aggregation effects of thymoquinone against Alzheimers -amyloid in vitro

(2016) Norsharina Ismail et al.   Journal of Medicinal Plants Research

Mitochondria-targeted antioxidant SkQT1 decreases trauma-induced neurological deficit in rat and prevents amyloid-β-induced impairment of long-term potentiation in rat hippocampal slices

(2015) Elisaveta E. Genrikhs et al.   JOURNAL OF DRUG TARGETING

Neuroprotective Effects of Mitochondria-Targeted Plastoquinone and Thymoquinone in a Rat Model of Brain Ischemia/Reperfusion Injury

(2015) Denis Silachev et al.   MOLECULES

Thymoquinone and its therapeutic potentials

(2015) Sara Darakhshan et al.   PHARMACOLOGICAL RESEARCH

Role of zinc and copper ions in the pathogenetic mechanisms of Alzheimer’s and Parkinson’s diseases

(2014) E. V. Stelmashook et al.   BIOCHEMISTRY-MOSCOW

Effect of thymoquinone on the lung pathology and cytokine levels of ovalbumin-sensitized guinea pigs

(2014) Rana Keyhanmanesh et al.   Pharmacological Reports

Thymoquinone Attenuates Trauma Induced Spinal Cord Damage in an Animal Model

(2014) Nilgun Ustun et al.   Ulusal Travma ve Acil Cerrahi Dergisi-Turkish Journal of Trauma & Emergency Surgery

Thymoquinone protects cultured rat primary neurons against amyloid β-induced neurotoxicity

(2013) A.H. Alhebshi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Thymoquinone Prevents β-Amyloid Neurotoxicity in Primary Cultured Cerebellar Granule Neurons

(2013) Norsharina Ismail et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

In search of novel highly active mitochondria-targeted antioxidants: Thymoquinone and its cationic derivatives

(2013) Inna I. Severina et al.   FEBS LETTERS

A Practical Synthesis and X-ray Crystallographic Analysis of Dithymoquinone, a Photodimer of Thymoquinone

(2013) Alan L. Myers et al.   LETTERS IN ORGANIC CHEMISTRY

Thymoquinone protects cultured hippocampal and human induced pluripotent stem cells-derived neurons against α-synuclein-induced synapse damage

(2013) A.H. Alhebshi et al.   NEUROSCIENCE LETTERS

Thymoquinone Inhibits Autophagy and Induces Cathepsin-Mediated, Caspase-Independent Cell Death in Glioblastoma Cells

(2013) Ira O. Racoma et al.   PLoS One

Dementia Resulting From Traumatic Brain Injury

(2012) Sharon Shively et al.   ARCHIVES OF NEUROLOGY

Neuroprotection with metformin and thymoquinone against ethanol-induced apoptotic neurodegeneration in prenatal rat cortical neurons

(2012) Ikram Ullah et al.   BMC NEUROSCIENCE

Depletion of GGA1 and GGA3 Mediates Postinjury Elevation of BACE1

(2012) K. R. Walker et al.   JOURNAL OF NEUROSCIENCE

Attenuation of Aβ-induced neurotoxicity by thymoquinone via inhibition of mitochondrial dysfunction and oxidative stress

(2012) Andleeb Khan et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

The Mitochondria-Targeted Antioxidants and Remote Kidney Preconditioning Ameliorate Brain Damage through Kidney-to-Brain Cross-Talk

(2012) Denis N. Silachev et al.   PLoS One

In vivo injected mitochondria-targeted plastoquinone antioxidant SkQR1 prevents β-amyloid-induced decay of long-term potentiation in rat hippocampal slices

(2011) N. A. Kapay et al.   BIOCHEMISTRY-MOSCOW

Amyloid  -Induced Impairments in Hippocampal Synaptic Plasticity Are Rescued by Decreasing Mitochondrial Superoxide

(2011) T. Ma et al.   JOURNAL OF NEUROSCIENCE

Prevention of cardiolipin oxidation and fatty acid cycling as two antioxidant mechanisms of cationic derivatives of plastoquinone (SkQs)

(2010) Vladimir P. Skulachev et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Protective effects of thymoquinone on the neuronal injury in frontal cortex after chronic toluene exposure

(2010) Mehmet Kanter   JOURNAL OF MOLECULAR HISTOLOGY

α-Synuclein and dopamine at the crossroads of Parkinson's disease

(2010) Lara Lourenço Venda et al.   TRENDS IN NEUROSCIENCES

Mitochondrial and apoptotic neuronal death signaling pathways in cerebral ischemia

(2009) Kuniyasu Niizuma et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

A review of Parkinson's disease

(2008) C. A. Davie   BRITISH MEDICAL BULLETIN

Stroke

(2008) Geoffrey A Donnan et al.   LANCET

Thymoquinone protects dopaminergic neurons against MPP+and rotenone

(2008) Khaled Radad et al.   PHYTOTHERAPY RESEARCH