Neuropharmacological Potential and Delivery Prospects of Thymoquinone for Neurological Disorders
出版年份 2018 全文链接
标题
Neuropharmacological Potential and Delivery Prospects of Thymoquinone for Neurological Disorders
作者
关键词
-
出版物
Oxidative Medicine and Cellular Longevity
Volume 2018, Issue -, Pages 1-17
出版商
Hindawi Limited
发表日期
2018-03-21
DOI
10.1155/2018/1209801
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Inhibition of neuroinflammation by thymoquinone requires activation of Nrf2/ARE signalling
- (2017) Ravikanth Velagapudi et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- N-of-1 trial of thymoquinone and vorinostat in a patient with sialidosis type 1
- (2017) Christina Liang et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- Oral bioavailability enhancement and hepatoprotective effects of thymoquinone by self-nanoemulsifying drug delivery system
- (2017) Mohd Abul Kalam et al. Materials Science & Engineering C-Materials for Biological Applications
- AMPK and SIRT1 activation contribute to inhibition of neuroinflammation by thymoquinone in BV2 microglia
- (2017) Ravikanth Velagapudi et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Minocycline reduces inflammatory parameters in the brain structures and serum and reverses memory impairment caused by the administration of amyloid β (1-42) in mice
- (2017) Michelle Lima Garcez et al. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
- Thymoquinone exerts neuroprotective effect in animal model of Parkinson’s disease
- (2017) Seyedeh Shohreh Ebrahimi et al. TOXICOLOGY LETTERS
- Synaptic Impairment in Alzheimer’s Disease: A Dysregulated Symphony
- (2017) Stefania Forner et al. TRENDS IN NEUROSCIENCES
- Neuroprotective Role of Atractylenolide-I in an In Vitro and In Vivo Model of Parkinson’s Disease
- (2017) et al. Nutrients
- Thymoquinone as a Potential Adjuvant Therapy for Cancer Treatment: Evidence from Preclinical Studies
- (2017) A.G.M. Mostofa et al. Frontiers in Pharmacology
- Anthelmintic Potential of Thymoquinone and Curcumin on Fasciola gigantica
- (2017) Rizwan Ullah et al. PLoS One
- Thymoquinone: An IRAK1 inhibitor with in vivo and in vitro anti-inflammatory activities
- (2017) Muhammad Jahangir Hossen et al. Scientific Reports
- Thymoquinone, a bioactive component of Nigella sativa, normalizes insulin secretion from pancreatic β-cells under glucose overload via regulation of malonyl-CoA
- (2016) Joshua P. Gray et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Selecting Good ‘Drug-Like’ Properties to Optimize Small Molecule Blood-Brain Barrier Penetration
- (2016) Paul C. Trippier CURRENT MEDICINAL CHEMISTRY
- The Role ofNigella sativaand Its Active Constituents in Learning and Memory
- (2016) Mohamad Khairul Azali Sahak et al. Evidence-based Complementary and Alternative Medicine
- Quantification and evaluation of thymoquinone loaded mucoadhesive nanoemulsion for treatment of cerebral ischemia
- (2016) Niyaz Ahmad et al. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
- Acute and subacute toxicity profiles of thymoquinone-loaded nanostructured lipid carrier in BALB/c mice
- (2016) Yong Sze Ong et al. International Journal of Nanomedicine
- Neuroprotective effects of thymoquinone against spinal cord ischemia-reperfusion injury by attenuation of inflammation, oxidative stress, and apoptosis
- (2016) Emre Cemal Gökce et al. JOURNAL OF NEUROSURGERY-SPINE
- Thymoquinone ameliorates lead-induced suppression of the antioxidant system in rat kidneys
- (2016) Aymen Mabrouk et al. Libyan Journal of Medicine
- Effects of thymoquinone, the major constituent of Nigella sativa seeds, on penicillin-induced epileptiform activity in rats
- (2016) Ersin Beyazcicek et al. Neurosciences
- Potential antidepressant constituents of Nigella sativa seeds
- (2016) EhabS Elkhayat et al. Pharmacognosy Magazine
- Neuroprotective Effects of Thymoquinone on the Hippocampus in a Rat Model of Traumatic Brain Injury
- (2016) İsmail Gülşen et al. World Neurosurgery
- Evaluation of Neuroprotective Effect of Thymoquinone Nanoformulation in the Rodent Cerebral Ischemia-Reperfusion Model
- (2016) Xiao-Yu Xiao et al. Biomed Research International
- Comparative Nephroprotective Effects of Silymarin, N-Acetylcysteine, and Thymoquinone Against Carbon Tetrachloride-Induced Nephrotoxicity in Rats
- (2016) Lokman Ustyol et al. Iranian Red Crescent Medical Journal
- The Effect of Thymoquinone, α7 Receptor Agonist and α7 Receptor Allosteric Modulator on the Cerebral Cortex in Experimentally Induced Alzheimer's Disease in Relation to MSCs Activation
- (2016) Lamiaa Ibrahim AbdEl Fattah et al. International Journal of Stem Cells
- Anti-aggregation effects of thymoquinone against Alzheimers -amyloid in vitro
- (2016) Norsharina Ismail et al. Journal of Medicinal Plants Research
- Xuefu Zhuyu decoction, a traditional Chinese medicine, provides neuroprotection in a rat model of traumatic brain injury via an anti-inflammatory pathway
- (2016) Zhihua Xing et al. Scientific Reports
- Thymoquinone Alleviates the Experimental Diabetic Peripheral Neuropathy by Modulation of Inflammation
- (2016) Long Chen et al. Scientific Reports
- Enhancement of Bioavailability and Pharmacodynamic Effects of Thymoquinone Via Nanostructured Lipid Carrier (NLC) Formulation
- (2015) Mohammed Elmowafy et al. AAPS PHARMSCITECH
- PEGylated-thymoquinone-nanoparticle mediated retardation of breast cancer cell migration by deregulation of cytoskeletal actin polymerization through miR-34a
- (2015) Saurav Bhattacharya et al. BIOMATERIALS
- An Evaluation of the Protective Effects of Thymoquinone on Amikacin-Induced Ototoxicity in Rats
- (2015) Fadlullah Aksoy et al. Clinical and Experimental Otorhinolaryngology
- Thymoquinone Protects against Myocardial Ischemic Injury by Mitigating Oxidative Stress and Inflammation
- (2015) Shreesh Ojha et al. Evidence-based Complementary and Alternative Medicine
- Immunomodulatory and cytotoxic effects of Nigella sativa and thymoquinone on rat splenocytes
- (2015) Zahra Gholamnezhad et al. FOOD AND CHEMICAL TOXICOLOGY
- Mitochondrial oxidative stress and dysfunction in arsenic neurotoxicity: A review
- (2015) Chandra Prakash et al. JOURNAL OF APPLIED TOXICOLOGY
- Anti-inflammatory effects of thymoquinone in activated BV-2 microglial cells
- (2015) Equar Taka et al. JOURNAL OF NEUROIMMUNOLOGY
- Neuroprotective Effects of Mitochondria-Targeted Plastoquinone and Thymoquinone in a Rat Model of Brain Ischemia/Reperfusion Injury
- (2015) Denis Silachev et al. MOLECULES
- Melatonin Attenuates Oxidative Damage Induced by Acrylamide In Vitro and In Vivo
- (2015) Xiaoqi Pan et al. Oxidative Medicine and Cellular Longevity
- Antipsychotic activity of standardizedBacopaextract against ketamine-induced experimental psychosis in mice: Evidence for the involvement of dopaminergic, serotonergic, and cholinergic systems
- (2015) Manavi Chatterjee et al. PHARMACEUTICAL BIOLOGY
- Black Cumin (Nigella sativa) and Its Active Constituent, Thymoquinone: An Overview on the Analgesic and Anti-inflammatory Effects
- (2015) Bahareh Amin et al. PLANTA MEDICA
- Thymoquinone Inhibits Escherichia coli ATP Synthase and Cell Growth
- (2015) Zulfiqar Ahmad et al. PLoS One
- Thymoquinone-Loaded Nanostructured Lipid Carrier Exhibited Cytotoxicity towards Breast Cancer Cell Lines (MDA-MB-231 and MCF-7) and Cervical Cancer Cell Lines (HeLa and SiHa)
- (2015) Wei Keat Ng et al. Biomed Research International
- Ameliorating effects of thymoquinone in rodent models of schizophrenia
- (2014) Ali Khan Rashid et al. African Journal of Pharmacy and Pharmacology
- Protective role of thymoquinone against liver damage induced by tamoxifen in female rats
- (2014) Ghada M. Suddek CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY
- Therapeutic Effects of Thymoquinone in a Model of Neuropathic Pain
- (2014) Feyzi Çelik et al. CURRENT THERAPEUTIC RESEARCH-CLINICAL AND EXPERIMENTAL
- Pharmacokinetic plasma behaviors of intravenous and oral bioavailability of thymoquinone in a rabbit model
- (2014) Khalid M. Alkharfy et al. EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS
- Chrysin Protects against Focal Cerebral Ischemia/Reperfusion Injury in Mice through Attenuation of Oxidative Stress and Inflammation
- (2014) Yang Yao et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Pomegranate extract protects against cerebral ischemia/reperfusion injury and preserves brain DNA integrity in rats
- (2014) Maha A.E. Ahmed et al. LIFE SCIENCES
- Thymoquinone and Vitamin C Attenuates Pentylenetetrazole-Induced Seizures Via Activation of GABAB1 Receptor in Adult Rats Cortex and Hippocampus
- (2014) Ikram Ullah et al. NEUROMOLECULAR MEDICINE
- Thymoquinone produced antianxiety-like effects in mice through modulation of GABA and NO levels
- (2014) Neeraj Gilhotra et al. Pharmacological Reports
- Effects of Intraperitoneal Thymoquinone on Chronic Neuropathic Pain in Rats
- (2014) Bahareh Amin et al. PLANTA MEDICA
- Thymoquinone Attenuates Trauma Induced Spinal Cord Damage in an Animal Model
- (2014) Nilgun Ustun et al. Ulusal Travma ve Acil Cerrahi Dergisi-Turkish Journal of Trauma & Emergency Surgery
- Neuroinflammation in the pathogenesis of Alzheimer’s disease. A rational framework for the search of novel therapeutic approaches
- (2014) Inelia Morales et al. Frontiers in Cellular Neuroscience
- Global prevalence and incidence of traumatic spinal cord injury
- (2014) Michael Fehlings et al. Clinical Epidemiology
- Thymoquinone protects cultured rat primary neurons against amyloid β-induced neurotoxicity
- (2013) A.H. Alhebshi et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- RETRACTED ARTICLE: Protective and antidiabetic effects of extract from Nigella sativa on blood glucose concentrations against streptozotocin (STZ)-induced diabetic in rats: an experimental study with histopathological evaluation
- (2013) Samad Alimohammadi et al. Diagnostic Pathology
- Inhibition of brain oxidative stress and inducible nitric oxide synthase expression by thymoquinone attenuates the development of morphine tolerance and dependence in mice
- (2013) Ahmed O. Abdel-Zaher et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Thymoquinone ameliorates lead-induced brain damage in Sprague Dawley rats
- (2013) Khaled Radad et al. EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY
- The effect of Nigella sativa Linn. seed on memory, attention and cognition in healthy human volunteers
- (2013) Muhammad Shahdaat Bin Sayeed et al. JOURNAL OF ETHNOPHARMACOLOGY
- Antioxidant Property, Thymoquinone Content and Chemical Characteristics of Different Extracts from Nigella sativa L. Seeds
- (2013) Zeinab Solati et al. JOURNAL OF THE AMERICAN OIL CHEMISTS SOCIETY
- Study on the Potential Toxicity of a Thymoquinone-Rich Fraction Nanoemulsion in Sprague Dawley Rats
- (2013) Zaki Tubesha et al. MOLECULES
- Radiation-modifying abilities of Nigella sativa and Thymoquinone on radiation-induced nitrosative stress in the brain tissue
- (2013) Adem Ahlatci et al. PHYTOMEDICINE
- Efficacy of Iranian Traditional Medicine in the Treatment of Epilepsy
- (2013) Mehri Abdollahi Fard et al. Biomed Research International
- Protective Effect ofThunbergia laurifolia(Linn.) on Lead Induced Acetylcholinesterase Dysfunction and Cognitive Impairment in Mice
- (2013) Moe Pwint Phyu et al. Biomed Research International
- The role of thymoquinone as antioxidant protection on oxidative stress induced by imidacloprid in male and female Swiss albino mice
- (2013) Sinan Ince et al. TOXICOLOGICAL AND ENVIRONMENTAL CHEMISTRY
- Neuroprotection with metformin and thymoquinone against ethanol-induced apoptotic neurodegeneration in prenatal rat cortical neurons
- (2012) Ikram Ullah et al. BMC NEUROSCIENCE
- Nanocarrier based formulation of Thymoquinone improves oral delivery: Stability assessment, in vitro and in vivo studies
- (2012) Anjali Singh et al. COLLOIDS AND SURFACES B-BIOINTERFACES
- Thymoquinone in liposomes: a study of loading efficiency and biological activity towards breast cancer
- (2012) Fadwa Odeh et al. DRUG DELIVERY
- Protective effect of thymoquinone against cisplatin-induced ototoxicity
- (2012) Mustafa Sagit et al. EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
- The influence of lipophilicity in drug discovery and design
- (2012) John A Arnott et al. Expert Opinion on Drug Discovery
- Thymoquinone as an anticancer agent: evidence from inhibition of cancer cells viability and invasion in vitro and tumor growthin vivo
- (2012) Samir Attoub et al. FUNDAMENTAL & CLINICAL PHARMACOLOGY
- Anti-inflammatory and antioxidant activity of thymoquinone in a rat model of acute bacterial prostatitis
- (2012) M Inci et al. HUMAN & EXPERIMENTAL TOXICOLOGY
- Characterization of Thymoquinone Binding to Human α1-Acid Glycoprotein
- (2012) Giulio Lupidi et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- The protective effect of green tea extract on lead induced oxidative and DNA damage on rat brain
- (2012) A.A. Khalaf et al. NEUROTOXICOLOGY
- Evidence of acrylamide induced oxidative stress and neurotoxicity in Drosophila melanogaster – Its amelioration with spice active enrichment: Relevance to neuropathy
- (2012) Sathya N. Prasad et al. NEUROTOXICOLOGY
- Antinociceptive Activity of Thymoquinone and its Structural Analogues: A Structure-Activity Relationship Study
- (2012) DP De Sousa et al. TROPICAL JOURNAL OF PHARMACEUTICAL RESEARCH
- Antibacterial activity of Thymoquinone, an active principle of Nigella sativa and its potency to prevent bacterial biofilm formation
- (2011) Kamel Chaieb et al. BMC Complementary and Alternative Medicine
- Radiosensitization in human breast carcinoma cells by thymoquinone: role of cell cycle and apoptosis
- (2011) Reelma Velho‑Pereira et al. CELL BIOLOGY INTERNATIONAL
- Neurobiology of Delusions in Alzheimer’s Disease
- (2011) Zahinoor Ismail et al. Current Psychiatry Reports
- RETRACTED: Thymoquinone poly (lactide-co-glycolide) nanoparticles exhibit enhanced anti-proliferative, anti-inflammatory, and chemosensitization potential
- (2010) Jayaraj Ravindran et al. BIOCHEMICAL PHARMACOLOGY
- Delivery of antiinflammatory nutraceuticals by nanoparticles for the prevention and treatment of cancer
- (2010) Hareesh B. Nair et al. BIOCHEMICAL PHARMACOLOGY
- Protective Effect of Nigella sativa Extract and Thymoquinone on Serum/Glucose Deprivation-Induced PC12 Cells Death
- (2010) S. H. Mousavi et al. CELLULAR AND MOLECULAR NEUROBIOLOGY
- Nigella sativa: Reduces the Risk of Various Maladies
- (2010) Masood Sadiq Butt et al. CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
- The effect of thymoquinone on intractable pediatric seizures (pilot study)
- (2010) Javad Akhondian et al. EPILEPSY RESEARCH
- Protective effects of thymoquinone on the neuronal injury in frontal cortex after chronic toluene exposure
- (2010) Mehmet Kanter JOURNAL OF MOLECULAR HISTOLOGY
- Thymoquinone, a potential therapeutic agent of Nigella sativa, binds to site I of human serum albumin
- (2010) G. Lupidi et al. PHYTOMEDICINE
- Impact of protein binding on thymoquinone's analytical detection
- (2010) N El-Najjar et al. PLANTA MEDICA
- Anti-inflammatory effects of the Nigella sativa seed extract, thymoquinone, in pancreatic cancer cells
- (2010) Navdeep Chehl et al. HPB
- Neuropathic Pain: A Maladaptive Response of the Nervous System to Damage
- (2009) Michael Costigan et al. Annual Review of Neuroscience
- Parkinson's Disease: From Molecular Pathways in Disease to Therapeutic Approaches
- (2009) Bobby Thomas ANTIOXIDANTS & REDOX SIGNALING
- Dry olive leaf extract ameliorates experimental autoimmune encephalomyelitis
- (2009) Djordje Miljković et al. CLINICAL NUTRITION
- Thymoquinone-induced suicidal erythrocyte death
- (2009) Syed M. Qadri et al. FOOD AND CHEMICAL TOXICOLOGY
- Effects of Nigella sativa Oil and Thymoquinone on Oxidative Stress and Neuropathy in Streptozotocin-Induced Diabetic Rats
- (2009) Nadia M. Hamdy et al. PHARMACOLOGY
- Thymoquinone supplementation induces quinone reductase and glutathione transferase in mice liver: possible role in protection against chemical carcinogenesis and toxicity
- (2009) Mahmoud N. Nagi et al. PHYTOTHERAPY RESEARCH
- In vitro toxicological properties of thymoquinone
- (2008) M. Khader et al. FOOD AND CHEMICAL TOXICOLOGY
- Thymoquinone protects dopaminergic neurons against MPP+and rotenone
- (2008) Khaled Radad et al. PHYTOTHERAPY RESEARCH
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