Organelle-specific autophagy in inflammatory diseases: a potential therapeutic target underlying the quality control of multiple organelles

Mitophagy Is Essential for Maintaining Cardiac Function During High Fat Diet-Induced Diabetic Cardiomyopathy

(2019) Mingming Tong et al.   CIRCULATION RESEARCH

Inhibition of ER Stress by 2-Aminopurine Treatment Modulates Cardiomyopathy in a Murine Chronic Chagas Disease Model

(2019) Janeesh Plakkal Ayyappan et al.   Biomolecules & Therapeutics

Autophagy regulates inflammatory programmed cell death via turnover of RHIM-domain proteins

(2019) Junghyun Lim et al.   eLife

The Multifunctional Sorting Protein PACS-2 Controls Mitophagosome Formation in Human Vascular Smooth Muscle Cells through Mitochondria-ER Contact Sites

(2019) Manon Moulis et al.   Cells

Autophagy: A Lysosome-Dependent Process with Implications in Cellular Redox Homeostasis and Human Disease

(2018) Stefan W. Ryter et al.   ANTIOXIDANTS & REDOX SIGNALING

Perfluoroalkyl acid exposure induces protective mitochondrial and endoplasmic reticulum autophagy in lung cells

(2018) Yan Xin et al.   ARCHIVES OF TOXICOLOGY

Catalase inhibition induces pexophagy through ROS accumulation

(2018) Joon No Lee et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Genetic aberrations in macroautophagy genes leading to diseases

(2018) Nienke van Beek et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Selective autophagy: The new player in the fight against neurodegenerative diseases?

(2018) Ming-Yue Wu et al.   BRAIN RESEARCH BULLETIN

Plastic mitochondria-endoplasmic reticulum (ER) contacts use chaperones and tethers to mould their structure and signaling

(2018) Thomas Simmen et al.   CURRENT OPINION IN CELL BIOLOGY

CCPG1 Is a Non-canonical Autophagy Cargo Receptor Essential for ER-Phagy and Pancreatic ER Proteostasis

(2018) Matthew D. Smith et al.   DEVELOPMENTAL CELL

Sepsis and septic shock

(2018) Maurizio Cecconi et al.   LANCET

NUFIP1 is a ribosome receptor for starvation-induced ribophagy

(2018) Gregory A. Wyant et al.   SCIENCE

Triggered recruitment of ESCRT machinery promotes endolysosomal repair

(2018) Michael L. Skowyra et al.   SCIENCE

Differential effects of reticulophagy and mitophagy on nonalcoholic fatty liver disease

(2018) Lijun Pang et al.   Cell Death & Disease

Pexophagy in yeast and mammals: an update on mysteries

(2018) Tanja Eberhart et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Parkin and PINK1 mitigate STING-induced inflammation

(2018) Danielle A. Sliter et al.   NATURE

Disrupted-in-schizophrenia-1 protects synaptic plasticity in a transgenic mouse model of Alzheimer’s disease as a mitophagy receptor

(2018) Zhao-Tao Wang et al.   AGING CELL

PRKN-regulated mitophagy and cellular senescence during COPD pathogenesis

(2018) Jun Araya et al.   Autophagy

NDP52 interacts with mitochondrial RNA poly(A) polymerase to promote mitophagy

(2018) Norihiko Furuya et al.   EMBO REPORTS

ER homeostasis and autophagy

(2017) Matthew Smith et al.   Essays in Biochemistry

Mitochondrial fission facilitates the selective mitophagy of protein aggregates

(2017) Jonathon L. Burman et al.   JOURNAL OF CELL BIOLOGY

Crosstalk of autophagy and apoptosis: Involvement of the dual role of autophagy under ER stress

(2017) Shuling Song et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Defective ATG16L1-mediated removal of IRE1α drives Crohn’s disease–like ileitis

(2017) Markus Tschurtschenthaler et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Autophagy protein ATG16L1 prevents necroptosis in the intestinal epithelium

(2017) Yu Matsuzawa-Ishimoto et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Progression of pathology in PINK1-deficient mouse brain from splicing via ubiquitination, ER stress, and mitophagy changes to neuroinflammation

(2017) Sylvia Torres-Odio et al.   Journal of Neuroinflammation

Ubiquitination of exposed glycoproteins by SCFFBXO27directs damaged lysosomes for autophagy

(2017) Yukiko Yoshida et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Peroxisomal Dysfunction in Age-Related Diseases

(2017) Cynthia M. Cipolla et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Parkin-Independent Mitophagy Controls Chemotherapeutic Response in Cancer Cells

(2017) Elodie Villa et al.   Cell Reports

Proteomic Analysis of the Human Tankyrase Protein Interaction Network Reveals Its Role in Pexophagy

(2017) Xu Li et al.   Cell Reports

The Host Protein Reticulon 3.1A Is Utilized by Flaviviruses to Facilitate Membrane Remodelling

(2017) Turgut E. Aktepe et al.   Cell Reports

TBK1: a new player in ALS linking autophagy and neuroinflammation

(2017) James A. Oakes et al.   Molecular Brain

Full length RTN3 regulates turnover of tubular endoplasmic reticulum via selective autophagy

(2017) Paolo Grumati et al.   eLife

Mitophagy Failure in Fibroblasts and iPSC-Derived Neurons of Alzheimer’s Disease-Associated Presenilin 1 Mutation

(2017) Patricia Martín-Maestro et al.   Frontiers in Molecular Neuroscience

Mitochondrial alterations during oxidative stress in chronic obstructive pulmonary disease

(2017) Ying Jiang et al.   International Journal of Chronic Obstructive Pulmonary Disease

Phosphorylation of the mitochondrial autophagy receptor Nix enhances its interaction with LC3 proteins

(2017) Vladimir V. Rogov et al.   Scientific Reports

Effect of disrupted mitochondria as a source of damage-associated molecular patterns on the production of tumor necrosis factor α by splenocytes from dogs

(2016) Steven G. Friedenberg et al.   AMERICAN JOURNAL OF VETERINARY RESEARCH

FUNDC1 is a novel mitochondrial-associated-membrane (MAM) protein required for hypoxia-induced mitochondrial fission and mitophagy

(2016) Wenxian Wu et al.   Autophagy

Interplay of endoplasmic reticulum stress and autophagy in neurodegenerative disorders

(2016) Yu Cai et al.   Autophagy

A novel PINK1- and PARK2-dependent protective neuroimmune pathway in lethal sepsis

(2016) Rui Kang et al.   Autophagy

SESN2/sestrin2 suppresses sepsis by inducing mitophagy and inhibiting NLRP3 activation in macrophages

(2016) Min-Ji Kim et al.   Autophagy

Loss of lamin B receptor is necessary to induce cellular senescence

(2016) Emilie Lukášová et al.   BIOCHEMICAL JOURNAL

Autophagic degradation of peroxisomes in mammals

(2016) Katarzyna Zientara-Rytter et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Autophagy, Inflammation, and Immunity: A Troika Governing Cancer and Its Treatment

(2016) Zhenyu Zhong et al.   CELL

Mitochondrial SIRT3 Mediates Adaptive Responses of Neurons to Exercise and Metabolic and Excitatory Challenges

(2016) Aiwu Cheng et al.   Cell Metabolism

Cardiac Fibrosis

(2016) Joshua G. Travers et al.   CIRCULATION RESEARCH

The peroxisome as a cell signaling organelle

(2016) Durga Nand Tripathi et al.   CURRENT OPINION IN CELL BIOLOGY

A TRIM16-Galectin3 Complex Mediates Autophagy of Damaged Endomembranes

(2016) Milana Fraiberg et al.   DEVELOPMENTAL CELL

TRIMs and Galectins Globally Cooperate and TRIM16 and Galectin-3 Co-direct Autophagy in Endomembrane Damage Homeostasis

(2016) Santosh Chauhan et al.   DEVELOPMENTAL CELL

VCP/p97 cooperates with YOD1, UBXD1 and PLAA to drive clearance of ruptured lysosomes by autophagy

(2016) Chrisovalantis Papadopoulos et al.   EMBO JOURNAL

FUNDC1 regulates mitochondrial dynamics at the ER–mitochondrial contact site under hypoxic conditions

(2016) Wenxian Wu et al.   EMBO JOURNAL

The PINK1, synphilin-1 and SIAH-1 complex constitutes a novel mitophagy pathway

(2016) Raymonde Szargel et al.   HUMAN MOLECULAR GENETICS

Syntaxin-17 delivers PINK1/parkin-dependent mitochondrial vesicles to the endolysosomal system

(2016) Gian-Luca McLelland et al.   JOURNAL OF CELL BIOLOGY

PINK1 disables the anti-fission machinery to segregate damaged mitochondria for mitophagy

(2016) Kenneth R. Pryde et al.   JOURNAL OF CELL BIOLOGY

PEX2 is the E3 ubiquitin ligase required for pexophagy during starvation

(2016) Graeme Sargent et al.   JOURNAL OF CELL BIOLOGY

FAM134B, the Selective Autophagy Receptor for Endoplasmic Reticulum Turnover, Inhibits Replication of Ebola Virus Strains Makona and Mayinga

(2016) Abhilash I. Chiramel et al.   JOURNAL OF INFECTIOUS DISEASES

Constitutive Autophagy and Nucleophagy during Epidermal Differentiation

(2016) Olufolake Akinduro et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

In Brief: Mitophagy: mechanisms and role in human disease

(2016) Maya Z Springer et al.   JOURNAL OF PATHOLOGY

CpG-ODN promotes phagocytosis and autophagy through JNK/P38 signal pathway in Staphylococcus aureus-stimulated macrophage

(2016) Hui-Mei Wu et al.   LIFE SCIENCES

Translocon component Sec62 acts in endoplasmic reticulum turnover during stress recovery

(2016) Fiorenza Fumagalli et al.   NATURE CELL BIOLOGY

Mitochondrial dynamics and mitophagy in Parkinson's disease: A fly point of view

(2016) Sophia Von Stockum et al.   NEUROBIOLOGY OF DISEASE

Phosphorylation of OPTN by TBK1 enhances its binding to Ub chains and promotes selective autophagy of damaged mitochondria

(2016) Benjamin Richter et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dynamic recruitment and activation of ALS-associated TBK1 with its target optineurin are required for efficient mitophagy

(2016) Andrew S. Moore et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

AMP-activated protein kinase mediates mitochondrial fission in response to energy stress

(2016) E. Q. Toyama et al.   SCIENCE

Mitophagy acts as a safeguard mechanism against human vascular smooth muscle cell apoptosis induced by atherogenic lipids

(2016) Audrey Swiader et al.   Oncotarget

The endoplasmic reticulum, not the pH gradient, drives calcium refilling of lysosomes

(2016) Abigail G Garrity et al.   eLife

The nuclear lamina in health and disease

(2016) Agnieszka Dobrzynska et al.   Nucleus

The nuclear lamina in health and disease

(2016) Agnieszka Dobrzynska et al.   Nucleus

Mitofusin 2 as a Driver That Controls Energy Metabolism and Insulin Signaling

(2015) Antonio Zorzano et al.   ANTIOXIDANTS & REDOX SIGNALING

EPAS1/HIF-2α is a driver of mammalian pexophagy

(2015) Miriam J Schönenberger et al.   Autophagy

PARK2-mediated mitophagy is involved in regulation of HBEC senescence in COPD pathogenesis

(2015) Saburo Ito et al.   Autophagy

Export-deficient monoubiquitinated PEX5 triggers peroxisome removal in SV40 large T antigen-transformed mouse embryonic fibroblasts

(2015) Marcus Nordgren et al.   Autophagy

Impaired mitophagy leads to cigarette smoke stress-induced cellular senescence: implications for chronic obstructive pulmonary disease

(2015) Tanveer Ahmad et al.   FASEB JOURNAL

The three ‘P’s of mitophagy: PARKIN, PINK1, and post-translational modifications

(2015) Thomas M. Durcan et al.   GENES & DEVELOPMENT

The mitochondrial protein BNIP3L is the substrate of PARK2 and mediates mitophagy in PINK1/PARK2 pathway

(2015) Feng Gao et al.   HUMAN MOLECULAR GENETICS

PARK2 enhancement is able to compensate mitophagy alterations found in sporadic Alzheimer's disease

(2015) Patricia Martín-Maestro et al.   HUMAN MOLECULAR GENETICS

UCP2-induced fatty acid synthase promotes NLRP3 inflammasome activation during sepsis

(2015) Jong-Seok Moon et al.   JOURNAL OF CLINICAL INVESTIGATION

Functional implications of mitofusin 2-mediated mitochondrial-SR tethering

(2015) Gerald W. Dorn et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Mitochondrial and lysosomal biogenesis are activated following PINK1/parkin-mediated mitophagy

(2015) Davor Ivankovic et al.   JOURNAL OF NEUROCHEMISTRY

Autophagy mediates degradation of nuclear lamina

(2015) Zhixun Dou et al.   NATURE

Regulation of endoplasmic reticulum turnover by selective autophagy

(2015) Aliaksandr Khaminets et al.   NATURE

Receptor-mediated selective autophagy degrades the endoplasmic reticulum and the nucleus

(2015) Keisuke Mochida et al.   NATURE

The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy

(2015) Michael Lazarou et al.   NATURE

ATM functions at the peroxisome to induce pexophagy in response to ROS

(2015) Jiangwei Zhang et al.   NATURE CELL BIOLOGY

Haploinsufficiency of TBK1 causes familial ALS and fronto-temporal dementia

(2015) Axel Freischmidt et al.   NATURE NEUROSCIENCE

SQSTM1splice site mutation in distal myopathy with rimmed vacuoles

(2015) Robert C. Bucelli et al.   NEUROLOGY

The Roles of PINK1, Parkin, and Mitochondrial Fidelity in Parkinson’s Disease

(2015) Alicia M. Pickrell et al.   NEURON

Parkin-mediated mitophagy directs perinatal cardiac metabolic maturation in mice

(2015) G. Gong et al.   SCIENCE

Bcl-2-like protein 13 is a mammalian Atg32 homologue that mediates mitophagy and mitochondrial fragmentation

(2015) Tomokazu Murakawa et al.   Nature Communications

Mitochondrial dynamics and mitochondrial quality control

(2015) Hong-Min Ni et al.   Redox Biology

NIX induces mitochondrial autophagy in reticulocytes

(2014) Ji Zhang et al.   Autophagy

Is the Rsp5 ubiquitin ligase involved in the regulation of ribophagy?

(2014) Claudine Kraft et al.   Autophagy

Autophagic degradation of nuclear components in mammalian cells

(2014) Young-Eun Park et al.   Autophagy

Choline dehydrogenase interacts with SQSTM1/p62 to recruit LC3 and stimulate mitophagy

(2014) Sungwoo Park et al.   Autophagy

The membrane peroxin PEX3 induces peroxisome-ubiquitination-linked pexophagy

(2014) Shun-ichi Yamashita et al.   Autophagy

AMBRA1 is able to induce mitophagy via LC3 binding, regardless of PARKIN and p62/SQSTM1

(2014) F Strappazzon et al.   CELL DEATH AND DIFFERENTIATION

Receptor-mediated mitophagy in yeast and mammalian systems

(2014) Lei Liu et al.   CELL RESEARCH

Reticulon 3 interacts with NS4B of the hepatitis C virus and negatively regulates viral replication by disrupting NS4B self-interaction

(2014) Ming-Jhan Wu et al.   CELLULAR MICROBIOLOGY

Loss of the m-AAA protease subunit AFG3L2 causes mitochondrial transport defects and tau hyperphosphorylation

(2014) A. K. Kondadi et al.   EMBO JOURNAL

ULK1 translocates to mitochondria and phosphorylates FUNDC1 to regulate mitophagy

(2014) W. Wu et al.   EMBO REPORTS

Cellular senescence and its effector programs

(2014) R. Salama et al.   GENES & DEVELOPMENT

Peroxin Pex14p is the key component for coordinated autophagic degradation of mammalian peroxisomes by direct binding to LC3-II

(2014) Li Jiang et al.   GENES TO CELLS

PINK1 Kinase Catalytic Activity Is Regulated by Phosphorylation on Serines 228 and 402

(2014) Liesbeth Aerts et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitophagy of damaged mitochondria occurs locally in distal neuronal axons and requires PINK1 and Parkin

(2014) Ghazaleh Ashrafi et al.   JOURNAL OF CELL BIOLOGY

PINK1 phosphorylates ubiquitin to activate Parkin E3 ubiquitin ligase activity

(2014) Lesley A. Kane et al.   JOURNAL OF CELL BIOLOGY

ER-associated degradation: Protein quality control and beyond

(2014) Annamaria Ruggiano et al.   JOURNAL OF CELL BIOLOGY

ER-phagy mediates selective degradation of endoplasmic reticulum independently of the core autophagy machinery

(2014) S. Schuck et al.   JOURNAL OF CELL SCIENCE

Mitophagy-dependent necroptosis contributes to the pathogenesis of COPD

(2014) Kenji Mizumura et al.   JOURNAL OF CLINICAL INVESTIGATION

Ultrastructural Characterization and Three-Dimensional Architecture of Replication Sites in Dengue Virus-Infected Mosquito Cells

(2014) J. Junjhon et al.   JOURNAL OF VIROLOGY

Translational and posttranslational regulation of XIAP by eIF2α and ATF4 promotes ER stress–induced cell death during the unfolded protein response

(2014) Nobuhiko Hiramatsu et al.   MOLECULAR BIOLOGY OF THE CELL

A Regulatory Signaling Loop Comprising the PGAM5 Phosphatase and CK2 Controls Receptor-Mediated Mitophagy

(2014) Guo Chen et al.   MOLECULAR CELL

Quality Control Autophagy Degrades Soluble ERAD-Resistant Conformers of the Misfolded Membrane Protein GnRHR

(2014) Scott A. Houck et al.   MOLECULAR CELL

Ubiquitin is phosphorylated by PINK1 to activate parkin

(2014) Fumika Koyano et al.   NATURE

MUL1 acts in parallel to the PINK1/parkin pathway in regulating mitofusin and compensates for loss of PINK1/parkin

(2014) Jina Yun et al.   eLife

Mutations in SQSTM1 encoding p62 in amyotrophic lateral sclerosis: genetics and neuropathology

(2013) Elisa Teyssou et al.   ACTA NEUROPATHOLOGICA

Mechanisms of Cardiac and Renal Dysfunction in Patients Dying of Sepsis

(2013) Osamu Takasu et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

When ER stress reaches a dead end

(2013) Hery Urra et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

SnapShot: Selective Autophagy

(2013) Meiyan Jin et al.   CELL

The machinery of macroautophagy

(2013) Yuchen Feng et al.   CELL RESEARCH

Uncoupling Protein 2 Deficiency Mimics the Effects of Hypoxia and Endoplasmic Reticulum Stress on Mitochondria and Triggers Pseudohypoxic Pulmonary Vascular Remodeling and Pulmonary Hypertension

(2013) Peter Dromparis et al.   CIRCULATION RESEARCH

Autophagy sequesters damaged lysosomes to control lysosomal biogenesis and kidney injury

(2013) Ikuko Maejima et al.   EMBO JOURNAL

Lamin B1 depletion in senescent cells triggers large-scale changes in gene expression and the chromatin landscape

(2013) P. P. Shah et al.   GENES & DEVELOPMENT

Autophagosomes form at ER–mitochondria contact sites

(2013) Maho Hamasaki et al.   NATURE

Cardiolipin externalization to the outer mitochondrial membrane acts as an elimination signal for mitophagy in neuronal cells

(2013) Charleen T. Chu et al.   NATURE CELL BIOLOGY

Permeability transition pore-mediated mitochondrial superoxide flashes mediate an early inhibitory effect of amyloid beta1−42 on neural progenitor cell proliferation

(2013) Yan Hou et al.   NEUROBIOLOGY OF AGING

The eIF2α/ATF4 pathway is essential for stress-induced autophagy gene expression

(2013) Wafa B’chir et al.   NUCLEIC ACIDS RESEARCH

PINK1-Phosphorylated Mitofusin 2 Is a Parkin Receptor for Culling Damaged Mitochondria

(2013) Y. Chen et al.   SCIENCE

Spatiotemporally controlled induction of autophagy-mediated lysosome turnover

(2013) Yu-Hsien Hung et al.   Nature Communications

Endothelial Peroxisomal Dysfunction and Impaired Pexophagy Promotes Oxidative Damage in Lipopolysaccharide-Induced Acute Kidney Injury

(2012) Radovan Vasko et al.   ANTIOXIDANTS & REDOX SIGNALING

Mitophagy is triggered by mild oxidative stress in a mitochondrial fission dependent manner

(2012) Magdalena Frank et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

A Vesicular Transport Pathway Shuttles Cargo from Mitochondria to Lysosomes

(2012) Vincent Soubannier et al.   CURRENT BIOLOGY

The RING-type ubiquitin ligases Pex2p, Pex10p and Pex12p form a heteromeric complex that displays enhanced activity in an ubiquitin conjugating enzyme-selective manner

(2012) Fouzi El Magraoui et al.   FEBS Journal

Endoplasmic reticulum stress and its regulator XBP-1 contributes to dendritic cell maturation and activation induced by high mobility group box-1 protein

(2012) Xiao-mei Zhu et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Microtubule-associated Protein 1 Light Chain 3 (LC3) Interacts with Bnip3 Protein to Selectively Remove Endoplasmic Reticulum and Mitochondria via Autophagy

(2012) Rita A. Hanna et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The impact of the unfolded protein response on human disease

(2012) Shiyu Wang et al.   JOURNAL OF CELL BIOLOGY

NBR1 acts as an autophagy receptor for peroxisomes

(2012) E. Deosaran et al.   JOURNAL OF CELL SCIENCE

Ablation of ALCAT1 Mitigates Hypertrophic Cardiomyopathy through Effects on Oxidative Stress and Mitophagy

(2012) X. Liu et al.   MOLECULAR AND CELLULAR BIOLOGY

NLRP3 is activated in Alzheimer’s disease and contributes to pathology in APP/PS1 mice

(2012) Michael T. Heneka et al.   NATURE

Mitochondrial outer-membrane protein FUNDC1 mediates hypoxia-induced mitophagy in mammalian cells

(2012) Lei Liu et al.   NATURE CELL BIOLOGY

Decreased parkin solubility is associated with impairment of autophagy in the nigrostriatum of sporadic Parkinson’s disease

(2012) I. Lonskaya et al.   NEUROSCIENCE

A Late Form of Nucleophagy in Saccharomyces cerevisiae

(2012) Dalibor Mijaljica et al.   PLoS One

PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65

(2012) C. Kondapalli et al.   Open Biology

Mitochondrial autophagy by Bnip3 involves Drp1-mediated mitochondrial fission and recruitment of Parkin in cardiac myocytes

(2011) Youngil Lee et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Autophagy: Renovation of Cells and Tissues

(2011) Noboru Mizushima et al.   CELL

The role of nuclear lamin B1 in cell proliferation and senescence

(2011) T. Shimi et al.   GENES & DEVELOPMENT

Peroxisome assembly: matrix and membrane protein biogenesis

(2011) Changle Ma et al.   JOURNAL OF CELL BIOLOGY

Parkin Interacts with Ambra1 to Induce Mitophagy

(2011) C. Van Humbeeck et al.   JOURNAL OF NEUROSCIENCE

UBQLN2/P62 cellular recycling pathways in amyotrophic lateral sclerosis and frontotemporal dementia

(2011) Faisal Fecto et al.   MUSCLE & NERVE

Nucleolar Disruption and Cajal Body Disassembly are Nuclear Hallmarks of DNA Damage-Induced Neurodegeneration in Purkinje Cells

(2010) Fernando C. Baltanás et al.   BRAIN PATHOLOGY

Cdc48 and Ufd3, new partners of the ubiquitin protease Ubp3, are required for ribophagy

(2010) Batool Ossareh-Nazari et al.   EMBO REPORTS

α-Synuclein impairs macroautophagy: implications for Parkinson’s disease

(2010) Ashley R. Winslow et al.   JOURNAL OF CELL BIOLOGY

Mutation in FAM134B causing severe hereditary sensory neuropathy: Figure 1

(2010) Sinéad M Murphy et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Mutations of optineurin in amyotrophic lateral sclerosis

(2010) Hirofumi Maruyama et al.   NATURE

PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1

(2010) Sven Geisler et al.   NATURE CELL BIOLOGY

Mechanisms of mitophagy

(2010) Richard J. Youle et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Exome Sequencing Reveals VCP Mutations as a Cause of Familial ALS

(2010) Janel O. Johnson et al.   NEURON

An Autophagy-Enhancing Drug Promotes Degradation of Mutant  1-Antitrypsin Z and Reduces Hepatic Fibrosis

(2010) T. Hidvegi et al.   SCIENCE

A ‘garbage can’ for ribosomes: how eukaryotes degrade their ribosomes

(2010) Denis L.J. Lafontaine   TRENDS IN BIOCHEMICAL SCIENCES

PINK1 Is Selectively Stabilized on Impaired Mitochondria to Activate Parkin

(2010) Derek P. Narendra et al.   PLOS BIOLOGY

Regulation Mechanisms and Signaling Pathways of Autophagy

(2009) Congcong He et al.   Annual Review of Genetics

Selective types of autophagy in yeast

(2009) Claudine Kraft et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Nix is a selective autophagy receptor for mitochondrial clearance

(2009) Ivana Novak et al.   EMBO REPORTS

Reduced Amyloid Deposition in Mice Overexpressing RTN3 Is Adversely Affected by Preformed Dystrophic Neurites

(2009) Q. Shi et al.   JOURNAL OF NEUROSCIENCE

Endoplasmic Reticulum Stress-Mediated Autophagy/Apoptosis Induced by Capsaicin (8-Methyl-N-vanillyl-6-nonenamide) and Dihydrocapsaicin is Regulated by the Extent of c-Jun NH2-Terminal Kinase/Extracellular Signal-Regulated Kinase Activation in WI38 Lung Epithelial Fibroblast Cells

(2009) S.-H. Oh et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Hypoxia-Induced Autophagy Is Mediated through Hypoxia-Inducible Factor Induction of BNIP3 and BNIP3L via Their BH3 Domains

(2009) G. Bellot et al.   MOLECULAR AND CELLULAR BIOLOGY

Mutations in FAM134B, encoding a newly identified Golgi protein, cause severe sensory and autonomic neuropathy

(2009) Ingo Kurth et al.   NATURE GENETICS

The peroxin Pex14p is involved in LC3-dependent degradation of mammalian peroxisomes

(2008) Sayuri Hara-Kuge et al.   EXPERIMENTAL CELL RESEARCH

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

(2008) Derek Narendra et al.   JOURNAL OF CELL BIOLOGY

Ordered Organelle Degradation during Starvation-induced Autophagy

(2008) Anders Riis Kristensen et al.   MOLECULAR & CELLULAR PROTEOMICS

Piecemeal Microautophagy of the Nucleus Requires the Core Macroautophagy Genes

(2008) R. Krick et al.   MOLECULAR BIOLOGY OF THE CELL

Mitofusin 2 tethers endoplasmic reticulum to mitochondria

(2008) Olga Martins de Brito et al.   NATURE

Autophagy fights disease through cellular self-digestion

(2008) Noboru Mizushima et al.   NATURE

Mature ribosomes are selectively degraded upon starvation by an autophagy pathway requiring the Ubp3p/Bre5p ubiquitin protease

(2008) Claudine Kraft et al.   NATURE CELL BIOLOGY

Ubiquitin signals autophagic degradation of cytosolic proteins and peroxisomes

(2008) P. K. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA