Shear Stress Regulation of Endothelial Glycocalyx Structure Is Determined by Glucobiosynthesis

Glomerular Function and Structural Integrity Depend on Hyaluronan Synthesis by Glomerular Endothelium

(2019) Bernard M. van den Berg et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

An efficient and scalable pipeline for epitope tagging in mammalian stem cells using Cas9 ribonucleoprotein

(2018) Pooran Singh Dewari et al.   eLife

Oscillatory wall shear stress is a dominant flow characteristic affecting lesion progression patterns and plaque vulnerability in patients with coronary artery disease

(2017) Lucas H. Timmins et al.   Journal of the Royal Society Interface

Heparanase: roles in cell survival, extracellular matrix remodelling and the development of kidney disease

(2017) Ton J. Rabelink et al.   Nature Reviews Nephrology

Inhibition of the Glycolytic Activator PFKFB3 in Endothelium Induces Tumor Vessel Normalization, Impairs Metastasis, and Improves Chemotherapy

(2016) Anna Rita Cantelmo et al.   CANCER CELL

Atrasentan Reduces Albuminuria by Restoring the Glomerular Endothelial Glycocalyx Barrier in Diabetic Nephropathy

(2016) Margien G.S. Boels et al.   DIABETES

Hyaluronan synthase control of synthesis rate and hyaluronan product size are independent functions differentially affected by mutations in a conserved tandem B-X7-B motif

(2016) Bruce A Baggenstoss et al.   GLYCOBIOLOGY

The glycocalyx and its significance in human medicine

(2016) J. M. Tarbell et al.   JOURNAL OF INTERNAL MEDICINE

Regulation of Hyaluronan Synthesis in Vascular Diseases and Diabetes

(2015) Paola Moretto et al.   Journal of Diabetes Research

Hyaluronan Synthase 1: A Mysterious Enzyme with Unexpected Functions

(2015) Hanna Siiskonen et al.   Frontiers in Immunology

Effects of shear stress pattern and magnitude on mesenchymal transformation and invasion of aortic valve endothelial cells

(2014) Gretchen J. Mahler et al.   BIOTECHNOLOGY AND BIOENGINEERING

TSG-6 Inhibits Neutrophil Migration via Direct Interaction with the Chemokine CXCL8

(2014) D. P. Dyer et al.   JOURNAL OF IMMUNOLOGY

Deeper Penetration of Erythrocytes into the Endothelial Glycocalyx Is Associated with Impaired Microvascular Perfusion

(2014) Dae Hyun Lee et al.   PLoS One

Quaking, an RNA-Binding Protein, Is a Critical Regulator of Vascular Smooth Muscle Cell Phenotype

(2013) Eric P. van der Veer et al.   CIRCULATION RESEARCH

Tissue distribution and subcellular localization of hyaluronan synthase isoenzymes

(2013) Kari Törrönen et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Hyaluronan Synthase 1 (HAS1) Requires Higher Cellular UDP-GlcNAc Concentration than HAS2 and HAS3

(2013) Kirsi Rilla et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Metabolic control of hyaluronan synthases

(2013) Davide Vigetti et al.   MATRIX BIOLOGY

Genome engineering using the CRISPR-Cas9 system

(2013) F Ann Ran et al.   Nature Protocols

Role of UDP-N-Acetylglucosamine (GlcNAc) andO-GlcNAcylation of Hyaluronan Synthase 2 in the Control of Chondroitin Sulfate and Hyaluronan Synthesis

(2012) Davide Vigetti et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Shear stress increases endothelial hyaluronan synthase 2 and hyaluronan synthesis especially in regard to an atheroprotective flow profile

(2011) Julian Maroski et al.   EXPERIMENTAL PHYSIOLOGY

Imaging proteins inside cells with fluorescent tags

(2011) Georgeta Crivat et al.   TRENDS IN BIOTECHNOLOGY

Proinflammatory Cytokines Induce Hyaluronan Synthesis and Monocyte Adhesion in Human Endothelial Cells through Hyaluronan Synthase 2 (HAS2) and the Nuclear Factor-κB (NF-κB) Pathway

(2010) Davide Vigetti et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fluorescent labeling of tetracysteine-tagged proteins in intact cells

(2010) Carsten Hoffmann et al.   Nature Protocols

Endothelial Surface Layer Degradation by Chronic Hyaluronidase Infusion Induces Proteinuria in Apolipoprotein E-Deficient Mice

(2010) Marijn C. Meuwese et al.   PLoS One

O-GlcNAc signaling: a metabolic link between diabetes and cancer?

(2010) C. Slawson et al.   TRENDS IN BIOCHEMICAL SCIENCES

Endothelial glycocalyx as potential diagnostic and therapeutic target in cardiovascular disease

(2008) Lysette N Broekhuizen et al.   CURRENT OPINION IN LIPIDOLOGY