Practical synthesis of C1 deuterated aldehydes enabled by NHC catalysis

Applications of deuterium in medicinal chemistry

(2019) Tracey Pirali et al.   JOURNAL OF MEDICINAL CHEMISTRY

Catalytic α-Selective Deuteration of Styrene Derivatives

(2019) Thomas R. Puleo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Highly Selective Directed Iridium-Catalyzed Hydrogen Isotope Exchange Reactions of Aliphatic Amides

(2018) Mégane Valero et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium/Rhodium Cooperative Catalysis for the Production of Aryl Aldehydes and Their Deuterated Analogues Using the Water-Gas Shift Reaction

(2018) Malek Y. S. Ibrahim et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Deuterium- and Tritium-Labelled Compounds: Applications in the Life Sciences

(2018) Jens Atzrodt et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

C−H Functionalisation for Hydrogen Isotope Exchange

(2018) Jens Atzrodt et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A General Strategy for Site-Selective Incorporation of Deuterium and Tritium into Pyridines, Diazines, and Pharmaceuticals

(2018) J. Luke Koniarczyk et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

One-Pot Synthesis of Deuterated Aldehydes from Arylmethyl Halides

(2018) Xiangmin Li et al.   ORGANIC LETTERS

Hydrogen/Deuterium (H/D) Exchange Catalysis in Alkanes

(2018) Aaron Sattler   ACS Catalysis

General and Practical Potassium Methoxide/Disilane-Mediated Dehalogenative Deuteration of (Hetero)Arylhalides

(2018) Xin Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Deoxygenative Deuteration of Carboxylic Acids with D2 O

(2018) Muliang Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

First deuterated drug approved

(2017) Charles Schmidt   NATURE BIOTECHNOLOGY

Recent advances in N-heterocyclic carbene catalyzed achiral synthesis

(2017) Qiao Ren et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Photoredox-catalyzed deuteration and tritiation of pharmaceutical compounds

(2017) Yong Yao Loh et al.   SCIENCE

Catalytic Deuteration of Aldehydes with D2O

(2017) Stephen Newman et al.   SYNLETT

Efficient Brønsted-Acid-Catalyzed Deuteration of Arenes and Their Transformation to Functionalized Deuterated Products

(2017) Xuewei Liang et al.   Asian Journal of Organic Chemistry

Stereoretentive Deuteration of α-Chiral Amines with D2O

(2016) Lillian V. A. Hale et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Iron-catalysed tritiation of pharmaceuticals

(2016) Renyuan Pony Yu et al.   NATURE

Deuterated drugs draw heavier backing

(2016) Asher Mullard   NATURE REVIEWS DRUG DISCOVERY

Divergent CH Insertion-Cyclization Cascades ofN-Allyl Ynamides

(2015) Holly V. Adcock et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Organocatalytic Reactions Enabled by N-Heterocyclic Carbenes

(2015) Darrin M. Flanigan et al.   CHEMICAL REVIEWS

Experimental and Theoretical Mechanistic Investigation of the Iridium-Catalyzed Dehydrogenative Decarbonylation of Primary Alcohols

(2015) Esben P. K. Olsen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

On the Mechanism of N-Heterocyclic Carbene-Catalyzed Reactions Involving Acyl Azoliums

(2014) Jessada Mahatthananchai et al.   ACCOUNTS OF CHEMICAL RESEARCH

Metal and carbene organocatalytic relay activation of alkynes for stereoselective reactions

(2014) Kayambu Namitharan et al.   Nature Communications

Organocatalytic umpolung: N-heterocyclic carbenes and beyond

(2012) Xavier Bugaut et al.   CHEMICAL SOCIETY REVIEWS

Method for regio-, chemo- and stereoselective deuterium labeling of sugars based on ruthenium-catalyzed C–H bond activation

(2010) Yuta Fujiwara et al.   CHEMICAL COMMUNICATIONS