标题
Thirty Years of Cancer Nanomedicine: Success, Frustration, and Hope
作者
关键词
-
出版物
Cancers
Volume 11, Issue 12, Pages 1855
出版商
MDPI AG
发表日期
2019-11-25
DOI
10.3390/cancers11121855
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Therapeutic Remodeling of the Tumor Microenvironment Enhances Nanoparticle Delivery
- (2019) Yuanxin Chen et al. Advanced Science
- Simultaneous T Cell Activation and Macrophage Polarization to Promote Potent Tumor Suppression by Iron Oxide-Embedded Large-Pore Mesoporous Organosilica Core-Shell Nanospheres
- (2019) Lin Chen et al. Advanced Healthcare Materials
- Polymeric Engineering of Nanoparticles for Highly Efficient Multifunctional Drug Delivery Systems
- (2019) Beatrice Fortuni et al. Scientific Reports
- Clinical cancer nanomedicine
- (2019) Joy Wolfram et al. Nano Today
- Nano-Strategies to Target Breast Cancer-Associated Fibroblasts: Rearranging the Tumor Microenvironment to Achieve Antitumor Efficacy
- (2019) Marta Truffi et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Combining Nanomedicine and Immunotherapy
- (2019) Yang Shi et al. ACCOUNTS OF CHEMICAL RESEARCH
- Nanomedicines for the Delivery of Biologics
- (2019) Wahlich et al. Pharmaceutics
- Co-Delivery of Natural Compounds with a Dual-Targeted Nanoparticle Delivery System for Improving Synergistic Therapy in an Orthotopic Tumor Model
- (2019) Pei-Yi Chu et al. ACS Applied Materials & Interfaces
- On the issue of transparency and reproducibility in nanomedicine
- (2019) Hon S. Leong et al. Nature Nanotechnology
- Engineering nanoparticles to locally activate T cells in the tumor microenvironment
- (2019) Dangge Wang et al. Science Immunology
- Survey of Clinical Translation of Cancer Nanomedicines—Lessons Learned from Successes and Failures
- (2019) Hongliang He et al. ACCOUNTS OF CHEMICAL RESEARCH
- Collagenase Nanoparticles Enhance the Penetration of Drugs into Pancreatic Tumors
- (2019) Assaf Zinger et al. ACS Nano
- Nanoparticle Interactions with the Tumor Microenvironment
- (2019) Yanyan Huai et al. BIOCONJUGATE CHEMISTRY
- Imatinib-loaded gold nanoparticles inhibit proliferation of fibroblasts and macrophages from systemic sclerosis patients and ameliorate experimental bleomycin-induced lung fibrosis
- (2019) Veronica Codullo et al. JOURNAL OF CONTROLLED RELEASE
- Are nanotechnological approaches the future of treating inflammatory diseases?
- (2019) Maria Antonietta Rizzuto et al. Nanomedicine
- A biodegradable nanocapsule delivers a Cas9 ribonucleoprotein complex for in vivo genome editing
- (2019) Guojun Chen et al. Nature Nanotechnology
- Linkage between endosomal escape of LNP-mRNA and loading into EVs for transport to other cells
- (2019) Marco Maugeri et al. Nature Communications
- Genetic programming of macrophages to perform anti-tumor functions using targeted mRNA nanocarriers
- (2019) F. Zhang et al. Nature Communications
- Directing Nanoparticle Biodistribution through Evasion and Exploitation of Stab2-Dependent Nanoparticle Uptake
- (2018) Frederick Campbell et al. ACS Nano
- Endosomal Size and Membrane Leakiness Influence Proton Sponge-Based Rupture of Endosomal Vesicles
- (2018) Lotte M. P. Vermeulen et al. ACS Nano
- Design of spherically structured 3D in vitro tumor models -Advances and prospects
- (2018) L.P. Ferreira et al. Acta Biomaterialia
- Perspectives on the past, present, and future of cancer nanomedicine
- (2018) Yu Seok Youn et al. ADVANCED DRUG DELIVERY REVIEWS
- Programmed Nanoparticle-Loaded Nanoparticles for Deep-Penetrating 3D Cancer Therapy
- (2018) Jinhwan Kim et al. ADVANCED MATERIALS
- Physical oncology: New targets for nanomedicine
- (2018) Alba Nicolas-Boluda et al. BIOMATERIALS
- Spred1 Safeguards Hematopoietic Homeostasis against Diet-Induced Systemic Stress
- (2018) Yuko Tadokoro et al. Cell Stem Cell
- Inhalable particulate drug delivery systems for lung cancer therapy: Nanoparticles, microparticles, nanocomposites and nanoaggregates
- (2018) Hadeer M. Abdelaziz et al. JOURNAL OF CONTROLLED RELEASE
- Regulatory T cell-targeted hybrid nanoparticles combined with immuno-checkpoint blockage for cancer immunotherapy
- (2018) Wenquan Ou et al. JOURNAL OF CONTROLLED RELEASE
- Nanoparticle transport pathways into tumors
- (2018) S. M. Moghimi et al. JOURNAL OF NANOPARTICLE RESEARCH
- Repolarization of Tumor-Associated Macrophages in a Genetically Engineered Nonsmall Cell Lung Cancer Model by Intraperitoneal Administration of Hyaluronic Acid-Based Nanoparticles Encapsulating MicroRNA-125b
- (2018) Neha N. Parayath et al. NANO LETTERS
- Nanomedicine for tumor microenvironment modulation and cancer treatment enhancement
- (2018) Jingjing Liu et al. Nano Today
- Factors relating to the biodistribution & clearance of nanoparticles & their effects on in vivo application
- (2018) Yanchun Wei et al. Nanomedicine
- Regulatory T cells in autoimmune disease
- (2018) Margarita Dominguez-Villar et al. NATURE IMMUNOLOGY
- Strategies to improve tumor penetration of nanomedicines through nanoparticle design
- (2018) Ya-Ru Zhang et al. Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology
- Progress and challenges towards targeted delivery of cancer therapeutics
- (2018) Daniel Rosenblum et al. Nature Communications
- Chick chorioallantoic membrane assay as an in vivo model to study the effect of nanoparticle-based anticancer drugs in ovarian cancer
- (2018) Binh Thanh Vu et al. Scientific Reports
- Biomimetic nanoparticles with enhanced affinity towards activated endothelium as versatile tools for theranostic drug delivery
- (2018) Jonathan O. Martinez et al. Theranostics
- Endogenous pH-responsive nanoparticles with programmable size changes for targeted tumor therapy and imaging applications
- (2018) Wei Wu et al. Theranostics
- The effects of surface charge on the intra-tumor penetration of drug delivery vehicles with tumor progression
- (2018) Donglin Han et al. Journal of Materials Chemistry B
- Current Trends and Challenges in the Clinical Translation of Nanoparticulate Nanomedicines: Pathways for Translational Development and Commercialization
- (2018) Susan Hua et al. Frontiers in Pharmacology
- Dual-Responsive Core Crosslinking Glycopolymer-Drug Conjugates Nanoparticles for Precise Hepatocarcinoma Therapy
- (2018) Jing Wu et al. Frontiers in Pharmacology
- Safety and Efficacy of BIND-014, a Docetaxel Nanoparticle Targeting Prostate-Specific Membrane Antigen for Patients With Metastatic Castration-Resistant Prostate Cancer
- (2018) Karen A. Autio et al. JAMA Oncology
- Nose-to-brain delivery of temozolomide-loaded PLGA nanoparticles functionalized with anti-EPHA3 for glioblastoma targeting
- (2018) Liuxiang Chu et al. DRUG DELIVERY
- The potential of biomimetic nanoparticles for tumor-targeted drug delivery
- (2018) Bowen Li et al. Nanomedicine
- Minimum information reporting in bio–nano experimental literature
- (2018) Matthew Faria et al. Nature Nanotechnology
- Size, Shape, and Protein Corona Determine Cellular Uptake and Removal Mechanisms of Gold Nanoparticles
- (2018) Lin Ding et al. Small
- Combination of NIR therapy and regulatory T cell modulation using layer-by-layer hybrid nanoparticles for effective cancer photoimmunotherapy
- (2018) Wenquan Ou et al. Theranostics
- Nanoparticle-Mediated Remodeling of the Tumor Microenvironment to Enhance Immunotherapy
- (2018) Sara Musetti et al. ACS Nano
- Stimuli-Responsive Nano-Architecture Drug-Delivery Systems to Solid Tumor Micromilieu: Past, Present, and Future Perspectives
- (2018) Hossam S. El-Sawy et al. ACS Nano
- The Endosomal Escape of Nanoparticles: Toward More Efficient Cellular Delivery
- (2018) Samuel A. Smith et al. BIOCONJUGATE CHEMISTRY
- Nano-targeted relaxin impairs fibrosis and tumor growth in pancreatic cancer and improves the efficacy of gemcitabine in vivo
- (2018) Deby F. Mardhian et al. JOURNAL OF CONTROLLED RELEASE
- Turning foes to friends: targeting cancer-associated fibroblasts
- (2018) Xueman Chen et al. NATURE REVIEWS DRUG DISCOVERY
- Cloaking nanoparticles with protein corona shield for targeted drug delivery
- (2018) Jun Yong Oh et al. Nature Communications
- Protein corona: a new approach for nanomedicine design
- (2017) Van Hong Nguyen et al. International Journal of Nanomedicine
- A potential non-invasive glioblastoma treatment: Nose-to-brain delivery of farnesylthiosalicylic acid incorporated hybrid nanoparticles
- (2017) Emine Sekerdag et al. JOURNAL OF CONTROLLED RELEASE
- Convection enhanced delivery of cisplatin-loaded brain penetrating nanoparticles cures malignant glioma in rats
- (2017) Clark Zhang et al. JOURNAL OF CONTROLLED RELEASE
- Lipid-coated calcium phosphate nanoparticle and beyond: a versatile platform for drug delivery
- (2017) Jia-Lin Huang et al. JOURNAL OF DRUG TARGETING
- Parameters Affecting the Enhanced Permeability and Retention Effect: The Need for Patient Selection
- (2017) Az Alddien Natfji et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Tumor Microenvironment-Responsive Multistaged Nanoplatform for Systemic RNAi and Cancer Therapy
- (2017) Xiaoding Xu et al. NANO LETTERS
- Protein nanocages that penetrate airway mucus and tumor tissue
- (2017) Xinglu Huang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Drug nanocarriers to treat autoimmunity and chronic inflammatory diseases
- (2017) Davide Prosperi et al. SEMINARS IN IMMUNOLOGY
- Biological Identity of Nanoparticles In Vivo : Clinical Implications of the Protein Corona
- (2017) Giulio Caracciolo et al. TRENDS IN BIOTECHNOLOGY
- Nanoescapology: progress toward understanding the endosomal escape of polymeric nanoparticles
- (2017) Laura I. Selby et al. Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology
- Targeting the Tumor Stroma: the Biology and Clinical Development of Pegylated Recombinant Human Hyaluronidase (PEGPH20)
- (2017) Kit Man Wong et al. Current Oncology Reports
- Biodegradable Hollow Mesoporous Silica Nanoparticles for Regulating Tumor Microenvironment and Enhancing Antitumor Efficiency
- (2017) Miao Kong et al. Theranostics
- Impact of semi-solid formulations on skin penetration of iron oxide nanoparticles
- (2017) Umberto M. Musazzi et al. JOURNAL OF NANOBIOTECHNOLOGY
- Modulating the Tumor Microenvironment to Enhance Tumor Nanomedicine Delivery
- (2017) Bo Zhang et al. Frontiers in Pharmacology
- Celecoxib normalizes the tumor microenvironment and enhances small nanotherapeutics delivery to A549 tumors in nude mice
- (2017) Bo Zhang et al. Scientific Reports
- A chloroquine-induced macrophage-preconditioning strategy for improved nanodelivery
- (2017) Joy Wolfram et al. Scientific Reports
- Smart Superstructures with Ultrahigh pH-Sensitivity for Targeting Acidic Tumor Microenvironment: Instantaneous Size Switching and Improved Tumor Penetration
- (2016) Hong-Jun Li et al. ACS Nano
- Absorption mechanism of DHP107, an oral paclitaxel formulation that forms a hydrated lipidic sponge phase
- (2016) Yura Jang et al. ACTA PHARMACOLOGICA SINICA
- Nanodrug Delivery: Is the Enhanced Permeability and Retention Effect Sufficient for Curing Cancer?
- (2016) Yuko Nakamura et al. BIOCONJUGATE CHEMISTRY
- Hypoxia-Responsive Polymersomes for Drug Delivery to Hypoxic Pancreatic Cancer Cells
- (2016) Prajakta Kulkarni et al. BIOMACROMOLECULES
- Low dose gemcitabine-loaded lipid nanocapsules target monocytic myeloid-derived suppressor cells and potentiate cancer immunotherapy
- (2016) Maria Stella Sasso et al. BIOMATERIALS
- Cancer nanomedicines: oversold or underappreciated?
- (2016) Roy van der Meel et al. Expert Opinion on Drug Delivery
- Insights into Protein–Ligand Interactions: Mechanisms, Models, and Methods
- (2016) Xing Du et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- To exploit the tumor microenvironment: Since the EPR effect fails in the clinic, what is the future of nanomedicine?
- (2016) F. Danhier JOURNAL OF CONTROLLED RELEASE
- Vascular bursts enhance permeability of tumour blood vessels and improve nanoparticle delivery
- (2016) Yu Matsumoto et al. Nature Nanotechnology
- Oral delivery of insulin via polyethylene imine-based nanoparticles for colonic release allows glycemic control in diabetic rats
- (2016) Lucia Salvioni et al. PHARMACOLOGICAL RESEARCH
- Tumour homing and therapeutic effect of colloidal nanoparticles depend on the number of attached antibodies
- (2016) Miriam Colombo et al. Nature Communications
- Optimization of the tumor microenvironment and nanomedicine properties simultaneously to improve tumor therapy
- (2016) Bo Zhang et al. Oncotarget
- Nanometronomic treatment of 4T1 breast cancer with nanocaged doxorubicin prevents drug resistance and circumvents cardiotoxicity
- (2016) Serena Mazzucchelli et al. Oncotarget
- Analysis of nanoparticle delivery to tumours
- (2016) Stefan Wilhelm et al. Nature Reviews Materials
- Surface modification of nanoparticles enables selective evasion of phagocytic clearance by distinct macrophage phenotypes
- (2016) Yaqing Qie et al. Scientific Reports
- Bioconjugated Manganese Dioxide Nanoparticles Enhance Chemotherapy Response by Priming Tumor-Associated Macrophages toward M1-like Phenotype and Attenuating Tumor Hypoxia
- (2015) Manli Song et al. ACS Nano
- Multistage Nanovehicle Delivery System Based on Stepwise Size Reduction and Charge Reversal for Programmed Nuclear Targeting of Systemically Administered Anticancer Drugs
- (2015) Lian Li et al. ADVANCED FUNCTIONAL MATERIALS
- Protein Corona of Nanoparticles: Distinct Proteins Regulate the Cellular Uptake
- (2015) Sandra Ritz et al. BIOMACROMOLECULES
- Preclinical Mouse Cancer Models: A Maze of Opportunities and Challenges
- (2015) Chi-Ping Day et al. CELL
- The nanoparticle biomolecule corona: lessons learned – challenge accepted?
- (2015) D. Docter et al. CHEMICAL SOCIETY REVIEWS
- Methoxy poly (ethylene glycol)-block-poly (glutamic acid)-graft-6-(2-nitroimidazole) hexyl amine nanoparticles for potential hypoxia-responsive delivery of doxorubicin
- (2015) Zaheer Ahmad et al. JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION
- Paclitaxel tumor priming promotes delivery and transfection of intravenous lipid-siRNA in pancreatic tumors
- (2015) Jie Wang et al. JOURNAL OF CONTROLLED RELEASE
- Improving drug delivery to solid tumors: Priming the tumor microenvironment
- (2015) Iftikhar Ali Khawar et al. JOURNAL OF CONTROLLED RELEASE
- RES blockade: A strategy for boosting efficiency of nanoparticle drug
- (2015) Ting Liu et al. Nano Today
- Tumour-associated macrophages act as a slow-release reservoir of nano-therapeutic Pt(IV) pro-drug
- (2015) Miles A. Miller et al. Nature Communications
- Radioactive 198Au-Doped Nanostructures with Different Shapes for In Vivo Analyses of Their Biodistribution, Tumor Uptake, and Intratumoral Distribution
- (2014) Kvar C. L. Black et al. ACS Nano
- Protein nanocages for self-triggered nuclear delivery of DNA-targeted chemotherapeutics in Cancer Cells
- (2014) Michela Bellini et al. JOURNAL OF CONTROLLED RELEASE
- Antiproliferative Effect of ASC-J9 Delivered by PLGA Nanoparticles against Estrogen-Dependent Breast Cancer Cells
- (2014) Paolo Verderio et al. MOLECULAR PHARMACEUTICS
- Overcoming the challenges in administering biopharmaceuticals: formulation and delivery strategies
- (2014) Samir Mitragotri et al. NATURE REVIEWS DRUG DISCOVERY
- A high M1/M2 ratio of tumor-associated macrophages is associated with extended survival in ovarian cancer patients
- (2014) Meiying Zhang et al. Journal of Ovarian Research
- Biodistribution of Different Sized Nanoparticles Assessed by Positron Emission Tomography: A General Strategy for Direct Activation of Metal Oxide Particles
- (2013) Carlos Pérez-Campaña et al. ACS Nano
- Targeting of Tumor-Associated Macrophages Made Possible by PEG-Sheddable, Mannose-Modified Nanoparticles
- (2013) Saijie Zhu et al. MOLECULAR PHARMACEUTICS
- Influence of tumour micro-environment heterogeneity on therapeutic response
- (2013) Melissa R. Junttila et al. NATURE
- Strategies for advancing cancer nanomedicine
- (2013) Vikash P. Chauhan et al. NATURE MATERIALS
- Stimuli-responsive nanocarriers for drug delivery
- (2013) Simona Mura et al. NATURE MATERIALS
- Microenvironmental regulation of tumor progression and metastasis
- (2013) Daniela F Quail et al. NATURE MEDICINE
- Rapid formation of plasma protein corona critically affects nanoparticle pathophysiology
- (2013) Stefan Tenzer et al. Nature Nanotechnology
- Peripherally Administered Nanoparticles Target Monocytic Myeloid Cells, Secondary Lymphoid Organs and Tumors in Mice
- (2013) Iraklis C. Kourtis et al. PLoS One
- Enhanced anticancer activity of nanopreparation containing an MMP2-sensitive PEG-drug conjugate and cell-penetrating moiety
- (2013) L. Zhu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Minimal "Self" Peptides That Inhibit Phagocytic Clearance and Enhance Delivery of Nanoparticles
- (2013) P. L. Rodriguez et al. SCIENCE
- Softer Zwitterionic Nanogels for Longer Circulation and Lower Splenic Accumulation
- (2012) Lei Zhang et al. ACS Nano
- Analysis on the current status of targeted drug delivery to tumors
- (2012) Il Keun Kwon et al. JOURNAL OF CONTROLLED RELEASE
- The big picture on nanomedicine: the state of investigational and approved nanomedicine products
- (2012) Michael L. Etheridge et al. Nanomedicine-Nanotechnology Biology and Medicine
- Normalization of tumour blood vessels improves the delivery of nanomedicines in a size-dependent manner
- (2012) Vikash P. Chauhan et al. Nature Nanotechnology
- Causes, consequences, and remedies for growth-induced solid stress in murine and human tumors
- (2012) T. Stylianopoulos et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Physicochemical Characteristics of Nanoparticles Affect Circulation, Biodistribution, Cellular Internalization, and Trafficking
- (2012) Xiaopin Duan et al. Small
- Nanoparticle Delivery of Cancer Drugs
- (2011) Andrew Z. Wang et al. Annual Review of Medicine
- Drug targeting to tumors: Principles, pitfalls and (pre-) clinical progress
- (2011) Twan Lammers et al. JOURNAL OF CONTROLLED RELEASE
- Gadolinium Chloride Augments Tumor-Specific Imaging of Targeted Quantum Dots In Vivo
- (2010) Parmeswaran Diagaradjane et al. ACS Nano
- Diffusion of Particles in the Extracellular Matrix: The Effect of Repulsive Electrostatic Interactions
- (2010) Triantafyllos Stylianopoulos et al. BIOPHYSICAL JOURNAL
- Complement activation cascade triggered by PEG–PL engineered nanomedicines and carbon nanotubes: The challenges ahead
- (2010) S.M. Moghimi et al. JOURNAL OF CONTROLLED RELEASE
- Small-molecule delivery by nanoparticles for anticancer therapy
- (2010) Zhuo (Georgia) Chen TRENDS IN MOLECULAR MEDICINE
- Controlled and targeted tumor chemotherapy by ultrasound-activated nanoemulsions/microbubbles
- (2009) Natalya Y. Rapoport et al. JOURNAL OF CONTROLLED RELEASE
- Pharmacokinetics and Biodistribution of Nanoparticles
- (2008) Shyh-Dar Li et al. MOLECULAR PHARMACEUTICS
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now