Disease gene prioritization by integrating tissue-specific molecular networks using a robust multi-network model

Phenome-based gene discovery provides information about Parkinson’s disease drug targets

(2016) Yang Chen et al.   BMC GENOMICS

Phenome-driven disease genetics prediction toward drug discovery

(2015) Yang Chen et al.   BIOINFORMATICS

ARG-walker: inference of individual specific strengths of meiotic recombination hotspots by population genomics analysis

(2015) Hao Chen et al.   BMC GENOMICS

Understanding multicellular function and disease with human tissue-specific networks

(2015) Casey S Greene et al.   NATURE GENETICS

Concordance of gene expression in human protein complexes reveals tissue specificity and pathology

(2013) Daniela Börnigen et al.   NUCLEIC ACIDS RESEARCH

Prediction and Validation of Gene-Disease Associations Using Methods Inspired by Social Network Analyses

(2013) U. Martin Singh-Blom et al.   PLoS One

Computational tools for prioritizing candidate genes: boosting disease gene discovery

(2012) Yves Moreau et al.   NATURE REVIEWS GENETICS

Tissue-Specific Functional Networks for Prioritizing Phenotype and Disease Genes

(2012) Yuanfang Guan et al.   PLoS Computational Biology

Enhancing the Prioritization of Disease-Causing Genes through Tissue Specific Protein Interaction Networks

(2012) Oded Magger et al.   PLoS Computational Biology

Inferring disease and gene set associations with rank coherence in networks

(2011) TaeHyun Hwang et al.   BIOINFORMATICS

Uncover disease genes by maximizing information flow in the phenome-interactome network

(2011) Y. Chen et al.   BIOINFORMATICS

ProDiGe: Prioritization Of Disease Genes with multitask machine learning from positive and unlabeled examples

(2011) Fantine Mordelet et al.   BMC BIOINFORMATICS

Genome-wide inferring gene–phenotype relationship by walking on the heterogeneous network

(2010) Yongjin Li et al.   BIOINFORMATICS

A global map of human gene expression

(2010) Margus Lukk et al.   NATURE BIOTECHNOLOGY

Network medicine: a network-based approach to human disease

(2010) Albert-László Barabási et al.   NATURE REVIEWS GENETICS

Associating Genes and Protein Complexes with Disease via Network Propagation

(2010) Oron Vanunu et al.   PLoS Computational Biology

Align human interactome with phenome to identify causative genes and networks underlying disease families

(2008) Xuebing Wu et al.   BIOINFORMATICS

A large-scale analysis of tissue-specific pathology and gene expression of human disease genes and complexes

(2008) K. Lage et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Geometric Interpretation of Gene Coexpression Network Analysis

(2008) Steve Horvath et al.   PLoS Computational Biology