Synthesis of Chalcone Derivatives: Inducing Apoptosis of HepG2 Cells via Regulating Reactive Oxygen Species and Mitochondrial Pathway
出版年份 2019 全文链接
标题
Synthesis of Chalcone Derivatives: Inducing Apoptosis of HepG2 Cells via Regulating Reactive Oxygen Species and Mitochondrial Pathway
作者
关键词
-
出版物
Frontiers in Pharmacology
Volume 10, Issue -, Pages -
出版商
Frontiers Media SA
发表日期
2019-11-16
DOI
10.3389/fphar.2019.01341
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- An orally antitumor chalcone hybrid inhibited HepG2 cells growth and migration as the tubulin binding agent
- (2019) Wang Yan et al. INVESTIGATIONAL NEW DRUGS
- How Does Chirality Determine the Selective Inhibition of Histone Deacetylase 6? A Lesson from Trichostatin A Enantiomers Based on Molecular Dynamics
- (2019) Yang Zhang et al. ACS Chemical Neuroscience
- An Improved Method for the Synthesis of Butein Using SOCl2/EtOH as Catalyst and Deciphering Its Inhibition Mechanism on Xanthine Oxidase
- (2019) Yu-Xue Hou et al. MOLECULES
- Discovery of a novel chalcone derivative inhibiting CFTR chloride channel via AMPK activation and its anti-diarrheal application
- (2019) Chamnan Yibcharoenporn et al. JOURNAL OF PHARMACOLOGICAL SCIENCES
- A novel chalcone derivative exerts anti-inflammatory and anti-oxidant effects after acute lung injury
- (2019) Yuting Lin et al. Aging-US
- Synthesis and biological evaluation of novel synthetic chalcone derivatives as anti-tumor agents targeting Cat L and Cat K
- (2018) Yali Wang et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Target ROS to induce apoptosis and cell cycle arrest by 5,7-dimethoxy-1,4-naphthoquinone derivative
- (2018) Kun Li et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Chalcones as putative hepatoprotective agents: Preclinical evidence and molecular mechanisms
- (2018) Elham Karimi-Sales et al. PHARMACOLOGICAL RESEARCH
- Toxicity of Cancer Therapies in Older Patients
- (2018) Olivia Le Saux et al. Current Oncology Reports
- Research progress on common adverse events caused by targeted therapy for colorectal cancer (Review)
- (2018) Bo Zhang et al. Oncology Letters
- Treatment of Elderly Patients with Colorectal Cancer
- (2018) Yoshiro Itatani et al. Biomed Research International
- Alpha-Santalol, a Component of Sandalwood Oil Inhibits Migration of Breast Cancer Cells by Targeting the β-catenin Pathway
- (2018) AJAY BOMMAREDDY et al. ANTICANCER RESEARCH
- Anti-Cancer Natural Products and Their Bioactive Compounds Inducing ER Stress-Mediated Apoptosis: A Review
- (2018) Changmin Kim et al. Nutrients
- A new chalcone derivative, 3-phenyl-1-(2,4,6-tris(methoxymethoxy)phenyl)prop-2-yn-1-one), inhibits phorbol ester-induced metastatic activity of colorectal cancer cells through upregulation of heme oxygenase-1
- (2018) Hao Jin et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Anti-Cancer and Protective Effects of Royal Jelly for Therapy-Induced Toxicities in Malignancies
- (2018) Yasuyoshi Miyata et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Synthesis of new chalcone-based homoserine lactones and their antiproliferative activity evaluation
- (2018) Bin Yu et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Synthesis and biological evaluation of novel pyrazolic chalcone derivatives as novel hepatocellular carcinoma therapeutics
- (2017) Mohammed M.A. Hawash et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Design, synthesis and cytotoxic activity of certain novel chalcone analogous compounds
- (2017) S. El-Meligie et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Novel 1-(7-ethoxy-1-benzofuran-2-yl) substituted chalcone derivatives: Synthesis, characterization and anticancer activity
- (2017) Demet Coskun et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Chalcone Derivatives: Promising Starting Points for Drug Design
- (2017) Marcelo Gomes et al. MOLECULES
- A novel chalcone derivative S17 induces apoptosis through ROS dependent DR5 up-regulation in gastric cancer cells
- (2017) Saiyang Zhang et al. Scientific Reports
- A novel quinazolinone chalcone derivative induces mitochondrial dependent apoptosis and inhibits PI3K/Akt/mTOR signaling pathway in human colon cancer HCT-116 cells
- (2016) Zahoor Ahmad Wani et al. FOOD AND CHEMICAL TOXICOLOGY
- Synthesis, Evaluation, and Mechanism Study of Novel Indole-Chalcone Derivatives Exerting Effective Antitumor Activity Through Microtubule Destabilization in Vitro and in Vivo
- (2016) Jun Yan et al. JOURNAL OF MEDICINAL CHEMISTRY
- Evaluation of Novel Chalcone Oximes as Inhibitors of Tyrosinase and Melanin Formation in B16 Cells
- (2015) Sini K. Radhakrishnan et al. ARCHIV DER PHARMAZIE
- Synthesis of apoptotic chalcone analogues in HepG2 human hepatocellular carcinoma cells
- (2015) Cheon-Soo Park et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Synthesis of Xanthohumol Analogues and Discovery of Potent Thioredoxin Reductase Inhibitor as Potential Anticancer Agent
- (2015) Baoxin Zhang et al. JOURNAL OF MEDICINAL CHEMISTRY
- Recent developments in biological activities of chalcones: A mini review
- (2014) Parvesh Singh et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Synthesis and Biological Evaluation of Novel Millepachine Derivatives As a New Class of Tubulin Polymerization Inhibitors
- (2014) Zhuang Yang et al. JOURNAL OF MEDICINAL CHEMISTRY
- Licochalcone A Suppresses Migration and Invasion of Human Hepatocellular Carcinoma Cells through Downregulation of MKK4/JNK via NF-κB Mediated Urokinase Plasminogen Activator Expression
- (2014) Jen-Pi Tsai et al. PLoS One
- Sulfenome mining in Arabidopsis thaliana
- (2014) C. Waszczak et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Deletion of MCL-1 causes lethal cardiac failure and mitochondrial dysfunction
- (2013) X. Wang et al. GENES & DEVELOPMENT
- Exploring Pharmacological Significance of Chalcone Scaffold: A Review
- (2012) N. K. Sahu et al. CURRENT MEDICINAL CHEMISTRY
- Curcumin targeting the thioredoxin system elevates oxidative stress in HeLa cells
- (2012) Wenqing Cai et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- zVAD-induced autophagic cell death requires c-Src-dependent ERK and JNK activation and reactive oxygen species generation
- (2011) Szu-Ying Chen et al. Autophagy
- Mitochondrial calcium regulates rat liver regeneration through the modulation of apoptosis
- (2011) Mateus T. Guerra et al. HEPATOLOGY
- Emerging role of Garcinol, the antioxidant chalcone from Garcinia indica Choisy and its synthetic analogs
- (2009) Subhash Padhye et al. Journal of Hematology & Oncology
- Bioenergetic pathways in tumor mitochondria as targets for cancer therapy and the importance of the ROS-induced apoptotic trigger
- (2009) Stephen J. Ralph et al. MOLECULAR ASPECTS OF MEDICINE
- Design, synthesis, and biological evaluation of Mannich bases of heterocyclic chalcone analogs as cytotoxic agents
- (2008) M. Vijaya Bhaskar Reddy et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Syntheses and potential anti-prostate cancer activities of ionone-based chalcones
- (2008) Jinming Zhou et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Studies of structure–activity relationship on plant polyphenol-induced suppression of human liver cancer cells
- (2008) Jacky Loa et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- SOCl2/EtOH: Catalytic system for synthesis of chalcones
- (2007) Ognyan Petrov et al. CATALYSIS COMMUNICATIONS
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