Extracellular Vesicles from Adipose-Derived Mesenchymal Stem Cells Downregulate Senescence Features in Osteoarthritic Osteoblasts

Paracrine effects of human adipose-derived mesenchymal stem cells in inflammatory stress-induced senescence features of osteoarthritic chondrocytes

(2016) Julia Platas et al.   Aging-US

Transplanted Senescent Cells Induce an Osteoarthritis-Like Condition in Mice

(2016) Ming Xu et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Anti-senescence and Anti-inflammatory Effects of the C-terminal Moiety of PTHrP Peptides in OA Osteoblasts

(2016) Julia Platas et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

The paracrine effect of adipose-derived stem cells inhibits osteoarthritis progression

(2015) Kazunari Kuroda et al.   BMC MUSCULOSKELETAL DISORDERS

Aging-related inflammation in osteoarthritis

(2015) M.A. Greene et al.   OSTEOARTHRITIS AND CARTILAGE

Mesenchymal stem cells for the management of inflammation in osteoarthritis: state of the art and perspectives

(2015) Y.-M. Pers et al.   OSTEOARTHRITIS AND CARTILAGE

Biogenesis, Secretion, and Intercellular Interactions of Exosomes and Other Extracellular Vesicles

(2014) Marina Colombo et al.   Annual Review of Cell and Developmental Biology

The Role of Inflammatory and Anti-Inflammatory Cytokines in the Pathogenesis of Osteoarthritis

(2014) Piotr Wojdasiewicz et al.   MEDIATORS OF INFLAMMATION

p16INK4a and its regulator miR-24 link senescence and chondrocyte terminal differentiation-associated matrix remodeling in osteoarthritis

(2014) Didier Philipot et al.   ARTHRITIS RESEARCH & THERAPY

Interleukin-10 Inhibits Bone Resorption: A Potential Therapeutic Strategy in Periodontitis and Other Bone Loss Diseases

(2014) Qian Zhang et al.   Biomed Research International

Osteoblast-Chondrocyte Interactions in Osteoarthritis

(2014) David M. Findlay et al.   Current Osteoporosis Reports

Adipose-Derived Mesenchymal Stem Cells Exert Antiinflammatory Effects on Chondrocytes and Synoviocytes From Osteoarthritis Patients Through Prostaglandin E2

(2013) Cristina Manferdini et al.   ARTHRITIS AND RHEUMATISM

Cellular senescence involves an intracrine prostaglandin E2 pathway in human fibroblasts

(2013) Sébastien Martien et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Cellular senescence and the senescent secretory phenotype: therapeutic opportunities

(2013) Tamara Tchkonia et al.   JOURNAL OF CLINICAL INVESTIGATION

Conditioned Media from Adipose-Tissue-Derived Mesenchymal Stem Cells Downregulate Degradative Mediators Induced by Interleukin-1βin Osteoarthritic Chondrocytes

(2013) Julia Platas et al.   MEDIATORS OF INFLAMMATION

Adipose mesenchymal stem cells protect chondrocytes from degeneration associated with osteoarthritis

(2013) Marie Maumus et al.   Stem Cell Research

Intra-articular delivery of adipose derived stromal cells attenuates osteoarthritis progression in an experimental rabbit model

(2013) Giovanna Desando et al.   ARTHRITIS RESEARCH & THERAPY

Antiinflammatory and chondroprotective effects of intraarticular injection of adipose-derived stem cells in experimental osteoarthritis

(2012) Menno ter Huurne et al.   ARTHRITIS AND RHEUMATISM

Aging processes and the development of osteoarthritis

(2012) Richard F. Loeser   CURRENT OPINION IN RHEUMATOLOGY

Subchondral bone and osteoarthritis: biological and cellular aspects

(2012) Y. Henrotin et al.   OSTEOPOROSIS INTERNATIONAL

Age-Related Disease Association of Endogenous γ-H2AX Foci in Mononuclear Cells Derived from Leukapheresis

(2012) Shepherd H. Schurman et al.   PLoS One

Senescence-associated intrinsic mechanisms of osteoblast dysfunctions

(2011) Moustapha Kassem et al.   AGING CELL

Heme oxygenase-1 mediates protective effects on inflammatory, catabolic and senescence responses induced by interleukin-1β in osteoarthritic osteoblasts

(2011) Victoria Clérigues et al.   BIOCHEMICAL PHARMACOLOGY

Increased proportion of hypermineralized osteocyte lacunae in osteoporotic and osteoarthritic human trabecular bone: Implications for bone remodeling

(2011) Vincent T. Carpentier et al.   BONE

Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders

(2011) Darren J. Baker et al.   NATURE

Decrease in the osteocyte lacunar density accompanied by hypermineralized lacunar occlusion reveals failure and delay of remodeling in aged human bone

(2010) Björn Busse et al.   AGING CELL

Inflammaging: The driving force in osteoporosis?

(2010) P. Lencel et al.   MEDICAL HYPOTHESES

Feedback between p21 and reactive oxygen production is necessary for cell senescence

(2010) João F Passos et al.   Molecular Systems Biology

Critical molecular regulators, histomorphometric indices and their correlations in the trabecular bone in primary hip osteoarthritis

(2010) D.D. Kumarasinghe et al.   OSTEOARTHRITIS AND CARTILAGE

Prostaglandins in bone: bad cop, good cop?

(2010) Katherine A. Blackwell et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Altered mineralization of human osteoarthritic osteoblasts is attributable to abnormal type I collagen production

(2009) Denis Couchourel et al.   ARTHRITIS AND RHEUMATISM

Aging and osteoarthritis: the role of chondrocyte senescence and aging changes in the cartilage matrix

(2009) R.F. Loeser   OSTEOARTHRITIS AND CARTILAGE

Enhanced expression of interleukin-6, matrix metalloproteinase-13, and receptor activator of NF-κB ligand in cells derived from osteoarthritic subchondral bone

(2008) Kei Sakao et al.   JOURNAL OF ORTHOPAEDIC SCIENCE

Proinflammatory cytokines inhibit osteogenic differentiation from stem cells: implications for bone repair during inflammation

(2008) D.C. Lacey et al.   OSTEOARTHRITIS AND CARTILAGE

Diacerein inhibits the synthesis of resorptive enzymes and reduces osteoclastic differentiation/survival in osteoarthritic subchondral bone: a possible mechanism for a protective effect against subchondral bone remodelling

(2008) Christelle Boileau et al.   ARTHRITIS RESEARCH & THERAPY