In vivo clonal expansion and phenotypes of hypocretin-specific CD4+ T cells in narcolepsy patients and controls

CD8+ T cells from patients with narcolepsy and healthy controls recognize hypocretin neuron-specific antigens

(2019) Natasja Wulff Pedersen et al.   Nature Communications

Improved methods for predicting peptide binding affinity to MHC class II molecules

(2018) Kamilla Kjaergaard Jensen et al.   IMMUNOLOGY

Disease-driving CD4+ T cell clonotypes persist for decades in celiac disease

(2018) Louise F. Risnes et al.   JOURNAL OF CLINICAL INVESTIGATION

Isolation of a Structural Mechanism for Uncoupling T Cell Receptor Signaling from Peptide-MHC Binding

(2018) Leah V. Sibener et al.   CELL

Pancreatic islets communicate with lymphoid tissues via exocytosis of insulin peptides

(2018) Xiaoxiao Wan et al.   NATURE

T cells in patients with narcolepsy target self-antigens of hypocretin neurons

(2018) Daniela Latorre et al.   NATURE

Autoimmunity to hypocretin and molecular mimicry to flu in type 1 narcolepsy

(2018) Guo Luo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identifying specificity groups in the T cell receptor repertoire

(2017) Jacob Glanville et al.   NATURE

Antigen presentation profiling reveals recognition of lymphoma immunoglobulin neoantigens

(2017) Michael S. Khodadoust et al.   NATURE

Absence of anti-hypocretin receptor 2 autoantibodies in post pandemrix narcolepsy cases

(2017) Guo Luo et al.   PLoS One

Narcolepsy Type 1 Is Associated with a Systemic Increase and Activation of Regulatory T Cells and with a Systemic Activation of Global T Cells

(2017) Michel Lecendreux et al.   PLoS One

High-dimensional single-cell analysis reveals the immune signature of narcolepsy

(2016) Felix J. Hartmann et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Large-scale detection of antigen-specific T cells using peptide-MHC-I multimers labeled with DNA barcodes

(2016) Amalie Kai Bentzen et al.   NATURE BIOTECHNOLOGY

CD8 T cell-mediated killing of orexinergic neurons induces a narcolepsy-like phenotype in mice

(2016) Raphaël Bernard-Valnet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CD4+ T-Cell Reactivity to Orexin/Hypocretin in Patients With Narcolepsy Type 1

(2016) Melanie Ramberger et al.   SLEEP

Re-examining the Nature and Function of Self-Reactive T cells

(2016) David M. Richards et al.   TRENDS IN IMMUNOLOGY

Atypical natural killer T-cell receptor recognition of CD1d–lipid antigens

(2016) Jérôme Le Nours et al.   Nature Communications

Efficient ex vivo analysis of CD4+ T-cell responses using combinatorial HLA class II tetramer staining

(2016) Hannes Uchtenhagen et al.   Nature Communications

CD4+ T-Cell Reactivity to Orexin/Hypocretin in Patients With Narcolepsy Type 1

(2016) Melanie Ramberger et al.   SLEEP

Development of a novel cell sorting method that samples population diversity in flow cytometry

(2015) Geoffrey W. Osborne et al.   CYTOMETRY PART A

Autoantibodies against ganglioside GM3 are associated with narcolepsy-cataplexy developing after Pandemrix vaccination against 2009 pandemic H1N1 type influenza virus

(2015) Anna-Helena Saariaho et al.   JOURNAL OF AUTOIMMUNITY

Antibodies to influenza nucleoprotein cross-react with human hypocretin receptor 2

(2015) Syed Sohail Ahmed et al.   Science Translational Medicine

pH-susceptibility of HLA-DO tunes DO/DM ratios to regulate HLA-DM catalytic activity

(2015) Wei Jiang et al.   Scientific Reports

International Classification of Sleep Disorders-Third Edition

(2014) Michael J Sateia   CHEST

Linking T-cell receptor sequence to functional phenotype at the single-cell level

(2014) Arnold Han et al.   NATURE BIOTECHNOLOGY

DQB1 Locus Alone Explains Most of the Risk and Protection in Narcolepsy with Cataplexy in Europe

(2014) et al.   SLEEP

T cell immunodominance is dictated by the positively selecting self-peptide

(2014) Wan-Lin Lo et al.   eLife

Virus-Specific CD4+ Memory-Phenotype T Cells Are Abundant in Unexposed Adults

(2013) Laura F. Su et al.   IMMUNITY

Cytokine-Dependent Induction of CD4+ T cells with Cytotoxic Potential during Influenza Virus Infection

(2013) L. Hua et al.   JOURNAL OF VIROLOGY

Combinatorial tetramer staining and mass cytometry analysis facilitate T-cell epitope mapping and characterization

(2013) Evan W Newell et al.   NATURE BIOTECHNOLOGY

Genome Wide Analysis of Narcolepsy in China Implicates Novel Immune Loci and Reveals Changes in Association Prior to Versus After the 2009 H1N1 Influenza Pandemic

(2013) Fang Han et al.   PLoS Genetics

ImmunoChip Study Implicates Antigen Presentation to T Cells in Narcolepsy

(2013) Juliette Faraco et al.   PLoS Genetics

Collaboration gets the most out of software

(2013) Andrew Morin et al.   eLife

Dissection of T-cell Antigen Specificity in Human Melanoma

(2012) R. S. Andersen et al.   CANCER RESEARCH

Increased Incidence and Clinical Picture of Childhood Narcolepsy following the 2009 H1N1 Pandemic Vaccination Campaign in Finland

(2012) Markku Partinen et al.   PLoS One

iMOSFLM: a new graphical interface for diffraction-image processing withMOSFLM

(2011) T. Geoff G. Battye et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Narcolepsy onset is seasonal and increased following the 2009 H1N1 pandemic in china

(2011) Fang Han et al.   ANNALS OF NEUROLOGY

Structural Basis of Specificity and Cross-Reactivity in T Cell Receptors Specific for Cytochrome c-I-E

(2011) E. W. Newell et al.   JOURNAL OF IMMUNOLOGY

Joint X-ray and neutron refinement withphenix.refine

(2010) Pavel V. Afonine et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Elevated Tribbles homolog 2–specific antibody levels in narcolepsy patients

(2010) Vesna Cvetkovic-Lopes et al.   JOURNAL OF CLINICAL INVESTIGATION

Common variants in P2RY11 are associated with narcolepsy

(2010) Birgitte R Kornum et al.   NATURE GENETICS

Narcolepsy is strongly associated with the T-cell receptor alpha locus

(2009) Joachim Hallmayer et al.   NATURE GENETICS

Epstein-Barr virus nuclear antigen 1-specific CD4+T cells directly kill Epstein-Barr virus-carrying natural killer and T cells

(2008) Ayako Demachi-Okamura et al.   CANCER SCIENCE

TGF-β: A Master of All T Cell Trades

(2008) Ming O. Li et al.   CELL

IMGT/V-QUEST: the highly customized and integrated system for IG and TR standardized V-J and V-D-J sequence analysis

(2008) X. Brochet et al.   NUCLEIC ACIDS RESEARCH