CD8+ T cells from patients with narcolepsy and healthy controls recognize hypocretin neuron-specific antigens

T cells in patients with narcolepsy target self-antigens of hypocretin neurons

(2018) Daniela Latorre et al.   NATURE

Autoimmunity to hypocretin and molecular mimicry to flu in type 1 narcolepsy

(2018) Guo Luo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Large-scale detection of antigen-specific T cells using peptide-MHC-I multimers labeled with DNA barcodes

(2016) Amalie Kai Bentzen et al.   NATURE BIOTECHNOLOGY

Molecular interrogation of hypothalamic organization reveals distinct dopamine neuronal subtypes

(2016) Roman A Romanov et al.   NATURE NEUROSCIENCE

CD8 T cell-mediated killing of orexinergic neurons induces a narcolepsy-like phenotype in mice

(2016) Raphaël Bernard-Valnet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Narcolepsy-Associated HLA Class I Alleles Implicate Cell-Mediated Cytotoxicity

(2016) Mehdi Tafti et al.   SLEEP

Narcolepsy-Associated HLA Class I Alleles Implicate Cell-Mediated Cytotoxicity

(2016) Mehdi Tafti et al.   SLEEP

HLA-DPB1 and HLA Class I Confer Risk of and Protection from Narcolepsy

(2015) Hanna M. Ollila et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Type 1 narcolepsy: a CD8+ T cell-mediated disease?

(2015) Matilda Degn et al.   Annals of the New York Academy of Sciences

Preproinsulin specific CD8+ T cells in subjects with latent autoimmune diabetes show lower frequency and different pathophysiological characteristics than those with type 1 diabetes

(2015) Naresh Sachdeva et al.   CLINICAL IMMUNOLOGY

Evolutionarily conserved regulation of hypocretin neuron specification by Lhx9

(2015) J. Liu et al.   DEVELOPMENT

Comment on “Antibodies to influenza nucleoprotein cross-react with human hypocretin receptor 2”

(2015) Anne Vassalli et al.   Science Translational Medicine

HLA DQB1*06:02 Negative Narcolepsy with Hypocretin/Orexin Deficiency

(2014) Fang Han et al.   SLEEP

Increased risk of narcolepsy in children and adults after pandemic H1N1 vaccination in France

(2013) Yves Dauvilliers et al.   BRAIN

Translational profiling of hypocretin neurons identifies candidate molecules for sleep regulation

(2013) J. Dalal et al.   GENES & DEVELOPMENT

Analysis of the Human Tissue-specific Expression by Genome-wide Integration of Transcriptomics and Antibody-based Proteomics

(2013) Linn Fagerberg et al.   MOLECULAR & CELLULAR PROTEOMICS

Increased Incidence and Clinical Picture of Childhood Narcolepsy following the 2009 H1N1 Pandemic Vaccination Campaign in Finland

(2012) Markku Partinen et al.   PLoS One

Narcolepsy onset is seasonal and increased following the 2009 H1N1 pandemic in china

(2011) Fang Han et al.   ANNALS OF NEUROLOGY

NetMHCcons: a consensus method for the major histocompatibility complex class I predictions

(2011) Edita Karosiene et al.   IMMUNOGENETICS

Counting absolute numbers of molecules using unique molecular identifiers

(2011) Teemu Kivioja et al.   NATURE METHODS

Elevated Tribbles homolog 2–specific antibody levels in narcolepsy patients

(2010) Vesna Cvetkovic-Lopes et al.   JOURNAL OF CLINICAL INVESTIGATION

The clinical features of cataplexy: A questionnaire study in narcolepsy patients with and without hypocretin-1 deficiency

(2010) Sebastiaan Overeem et al.   SLEEP MEDICINE

A scaling normalization method for differential expression analysis of RNA-seq data

(2010) Mark D Robinson et al.   GENOME BIOLOGY

IGFBP3 Colocalizes with and Regulates Hypocretin (Orexin)

(2009) Makoto Honda et al.   PLoS One

Design of 240,000 orthogonal 25mer DNA barcode probes

(2009) Q. Xu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Blood CD8+T cell responses against myelin determinants in multiple sclerosis and healthy individuals

(2008) Laureline Berthelot et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Nocturnal aspects of narcolepsy with cataplexy

(2008) Giuseppe Plazzi et al.   SLEEP MEDICINE REVIEWS