Narcolepsy Type 1 Is Associated with a Systemic Increase and Activation of Regulatory T Cells and with a Systemic Activation of Global T Cells

Elevated Anti-Streptococcal Antibodies in Patients with Recent Narcolepsy Onset

(2017) Adi Aran et al.   SLEEP

HLA-DPB1 and HLA Class I Confer Risk of and Protection from Narcolepsy

(2015) Hanna M. Ollila et al.   AMERICAN JOURNAL OF HUMAN GENETICS

TCR sequences and tissue distribution discriminate the subsets of naïve and activated/memory Treg cells in mice

(2015) Anne-Sophie Bergot et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Autoantibodies against ganglioside GM3 are associated with narcolepsy-cataplexy developing after Pandemrix vaccination against 2009 pandemic H1N1 type influenza virus

(2015) Anna-Helena Saariaho et al.   JOURNAL OF AUTOIMMUNITY

Impact of cytokine in type 1 narcolepsy: Role of pandemic H1N1 vaccination ?

(2015) Michel Lecendreux et al.   JOURNAL OF AUTOIMMUNITY

Increased β-haemolytic group A streptococcal M6 serotype and streptodornase B-specific cellular immune responses in Swedish narcolepsy cases

(2015) A. Ambati et al.   JOURNAL OF INTERNAL MEDICINE

Hypocretin (orexin) biology and the pathophysiology of narcolepsy with cataplexy

(2015) Roland S Liblau et al.   LANCET NEUROLOGY

Narcolepsy link to pandemic flu vaccine becomes clearer

(2015) G. Vogel   SCIENCE

Antibodies to influenza nucleoprotein cross-react with human hypocretin receptor 2

(2015) Syed Sohail Ahmed et al.   Science Translational Medicine

Decline of FoxP3+ Regulatory CD4 T Cells in Peripheral Blood of Children Heavily Exposed to Malaria

(2015) Michelle J. Boyle et al.   PLoS Pathogens

Narcolepsy, 2009 A(H1N1) pandemic influenza, and pandemic influenza vaccinations: What is known and unknown about the neurological disorder, the role for autoimmunity, and vaccine adjuvants

(2014) S. Sohail Ahmed et al.   JOURNAL OF AUTOIMMUNITY

Low Thymic Output, Peripheral Homeostasis Deregulation, and Hastened Regulatory T Cells Differentiation in Children with 22q11.2 Deletion Syndrome

(2014) Sara Ferrando-Martínez et al.   JOURNAL OF PEDIATRICS

CSF beta-amyloid levels are altered in narcolepsy: a link with the inflammatory hypothesis?

(2014) Claudio Liguori et al.   JOURNAL OF SLEEP RESEARCH

Narcolepsy as an autoimmune disease: the role of H1N1 infection and vaccination

(2014) Markku Partinen et al.   LANCET NEUROLOGY

Narcolepsy and influenza A(H1N1) pandemic 2009 vaccination in the United States

(2014) J. Duffy et al.   NEUROLOGY

Increased risk of narcolepsy in children and adults after pandemic H1N1 vaccination in France

(2013) Yves Dauvilliers et al.   BRAIN

Translational profiling of hypocretin neurons identifies candidate molecules for sleep regulation

(2013) J. Dalal et al.   GENES & DEVELOPMENT

Passive transfer of narcolepsy: Anti-TRIB2 autoantibody positive patient IgG causes hypothalamic orexin neuron loss and sleep attacks in mice

(2013) Aviva Katzav et al.   JOURNAL OF AUTOIMMUNITY

Increased childhood incidence of narcolepsy in western Sweden after H1N1 influenza vaccination

(2013) A. Szakacs et al.   NEUROLOGY

Changes in Natural Foxp3+Treg but Not Mucosally-Imprinted CD62LnegCD38+Foxp3+Treg in the Circulation of Celiac Disease Patients

(2013) Marieke A. van Leeuwen et al.   PLoS One

Increased plasma level of tumor necrosis factor α in patients with narcolepsy in Taiwan

(2013) Yun-Hsiang Chen et al.   SLEEP MEDICINE

Childhood narcolepsy with cataplexy: comparison between post-H1N1 vaccination and sporadic cases

(2013) Fabio Pizza et al.   SLEEP MEDICINE

Genome Wide Analysis of Narcolepsy in China Implicates Novel Immune Loci and Reveals Changes in Association Prior to Versus After the 2009 H1N1 Influenza Pandemic

(2013) Fang Han et al.   PLoS Genetics

ImmunoChip Study Implicates Antigen Presentation to T Cells in Narcolepsy

(2013) Juliette Faraco et al.   PLoS Genetics

Decreased incidence of childhood narcolepsy 2 years after the 2009 H1N1 winter flu pandemic

(2012) Fang Han et al.   ANNALS OF NEUROLOGY

Mechanism for Hypocretin-mediated sleep-to-wake transitions

(2012) M. E. Carter et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Narcolepsy as an adverse event following immunization: Case definition and guidelines for data collection, analysis and presentation

(2012) Francesca Poli et al.   VACCINE

Narcolepsy onset is seasonal and increased following the 2009 H1N1 pandemic in china

(2011) Fang Han et al.   ANNALS OF NEUROLOGY

Regulatory T-Cell Responses to Low-Dose Interleukin-2 in HCV-Induced Vasculitis

(2011) David Saadoun et al.   NEW ENGLAND JOURNAL OF MEDICINE

T Regulatory Cells Are Markers of Disease Activity in Multiple Sclerosis Patients

(2011) Dacia Dalla Libera et al.   PLoS One

Narcolepsy: autoimmunity, effector T cell activation due to infection, or T cell independent, major histocompatibility complex class II induced neuronal loss?

(2010) Adriano Fontana et al.   BRAIN

Elevated Tribbles homolog 2–specific antibody levels in narcolepsy patients

(2010) Vesna Cvetkovic-Lopes et al.   JOURNAL OF CLINICAL INVESTIGATION

Common variants in P2RY11 are associated with narcolepsy

(2010) Birgitte R Kornum et al.   NATURE GENETICS

Increased Th17 cells are accompanied by FoxP3+ Treg cell accumulation and correlated with psoriasis disease severity

(2009) Li Zhang et al.   CLINICAL IMMUNOLOGY

Defects in IL-2R Signaling Contribute to Diminished Maintenance of FOXP3 Expression in CD4+CD25+ Regulatory T-Cells of Type 1 Diabetic Subjects

(2009) S. A. Long et al.   DIABETES

Polymorphism located in TCRA locus confers susceptibility to essential hypersomnia with HLA-DRB1*1501-DQB1*0602 haplotype

(2009) Taku Miyagawa et al.   JOURNAL OF HUMAN GENETICS

Narcolepsy is strongly associated with the T-cell receptor alpha locus

(2009) Joachim Hallmayer et al.   NATURE GENETICS

Regulatory T cells exert checks and balances on self tolerance and autoimmunity

(2009) Kajsa Wing et al.   NATURE IMMUNOLOGY

Regulatory T Cells and Immune Tolerance

(2008) Shimon Sakaguchi et al.   CELL